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      • KCI등재

        Graphene oxide based heterojunction TiO2–ZnO catalysts with outstanding photocatalytic performance for bisphenol-A, ibuprofen and flurbiprofen

        Esra Bilgin Simsek,Bayram Kilic,Mansur Asgin,Ayse Akan 한국공업화학회 2018 Journal of Industrial and Engineering Chemistry Vol.59 No.-

        Reduced graphene oxide based TiO2–ZnO nanostructures (RGO/TiO2/ZnO) are growth by hydrothermal method and characterized by SEM, XPS, XRD, and UV–vis analyses. XRD analysis confirmed the formation of wurtzite ZnO and anatase TiO2 over the tandem nanostructure. The UV–vis spectrum indicated that the hybrid catalyst has the lowest band gap energy (Eg = 2.5 eV). Photocatalytic degradation of the catalysts towards estrogen (bisphenol-A) and pharmaceuticals (ibuprofen, flurbiprofen) was investigated under UV and visible light irradiation. The heterojunction RGO/TiO2/ZnO catalyst exhibited greater photocatalytic activity than bifunctional RGO/TiO2 and TiO2/ZnO.

      • KCI등재

        Simultaneous ICP-OES determination of trace metals in water and food samples after their preconcentration on silica gel functionalized with N-(2-aminoethyl)-2,3-dihydroxybenzaldimine

        Esra Durduran,Huseyin Altundag,Mustafa Imamoglu,Salih Zeki Yıldız,Mustafa Tuzen 한국공업화학회 2015 Journal of Industrial and Engineering Chemistry Vol.27 No.-

        Silica gel was functionalized with N-(2-aminoethyl)-2,3-dihydroxybenzaldimine group (AEDHB-SG) andcharacterized by elemental analysis and FT-IR spectroscopy. Preconcentration conditions of Cd(II), Cu(II),Ni(II) and Pb(II) were investigated on the AEDHB-SG loaded column using a solid phase extractiontechnique. The effects of parameters such as the pH, sample volume, flow rates, matrix ions wereexamined. Adsorption capacity of AEDHB-SG for Cd(II), Cu(II), Ni(II) and Pb(II) was 0.40, 0.56, 0.50 and0.23 mmol g 1. The accuracy of the developed method was confirmed by certified reference materials. Optimized method was applied to water and food samples for the determination of trace metals usingICP-OES.

      • KCI등재

        Prospective English teachers' views on the physical environment, human resources, and program of their departments

        Esra Eret 서울대학교 교육연구소 2010 Asia Pacific Education Review Vol.11 No.4

        The quality of teacher education, in general, is affected from a number of variables such as physical environment of the institutions, instructor quality, the curriculum implemented, administrative support, and others. As the input of the system, the perspectives of the students on those variables also influence the direction and the quality of the education taking place in the colleges of education. Regarding this, the purpose of the present study is to identify and compare the perspectives of fourth-year English Language Teaching students on the physical environment, human resources, and the program of three ELT departments at three different state universities. As part of the survey research design, the questionnaire was administered to totally 278 prospective English Teachers from the ELT departments at state universities in Ankara. The results of the study, unlike the past research on the issue, presented that the prospective English teachers had positive views on the instructors and program generally; however, they stated problems on the physical environment of their departments. Moreover, there were significant differences in students' views on the physical environment, resources, and its sub-dimensions. The students from the institution, which was renovated before the study, had more positive views on their department than the others. The results suggested it might be useful to reevaluate and reconsider the current conditions of the English language teacher education in relation to the departments' human resources, program and especially the physical environment.

      • KCI등재

        Anticancer activities of bioactive peptides derived from rice husk both in free and encapsulated form in chitosan

        Esra Ilhan-Ayisigi,Gozde Budak,Melih Soner Celiktas,Canan Sevimli-Gur,Ozlem Yesil-Celiktas 한국공업화학회 2021 Journal of Industrial and Engineering Chemistry Vol.103 No.-

        Cereal grain-derived protein hydrolysates exert beneficial effects for human health, thus utilization of byproductswith high protein content has drawn attention. In this study, hot water extraction of rice huskhas been optimized to obtain protein hydrolysate with the highest anticancer activity. The optimum proteinvalue was obtained as 2.40 g/L corresponding to 43.2 g protein/kg dried rice husk under the conditionsof 60 C, 2.0 mL/min flow rate and pH 10.0. The protein hydrolysate was encapsulated with chitosan,where the mean particle size of protein hydrolysate (0.3 %) loaded chitosan nanoparticles was 256.4 ± 33. 4 nm with 89 % encapsulation efficiency and a 65% release at the end of 6 days. Cytotoxicity assaysshowed that the lowest cell viabilities have been achieved with A549 and MCF7 cells with IC50 valuesof 1.98 and 3.58 mg/mL, respectively, whereas nuclear fragmentation and apoptotic bodies were observedthrough Hoechst 33342 staining. The cytotoxic effect might be associated with the wide variety of peptide/protein subunits ranging from 10 kDa to more than 180 kDa in the protein hydrolysate of rice husk.

      • KCI등재

        Evaluation of Serum Omentin-1, Vaspin, Leptin, Adiponectin Levels in Obese/Overweight Children and Their Relationship With Non-Alcoholic Fatty Liver Disease

        Esra Akyüz Özkan,Allahverdi Sadigov,Osman Öztürk 한국임상영양학회 2022 Clinical Nutrition Research Vol.11 No.3

        To investigate adipokines (vaspin, omentin-1, adiponectin and leptin) and their correlation with hepatosteatosis degree in obese/overweight (O/O) children. We analyzed adipokine levels of 81 children (49 O/O, [body mass index (BMI) > 95th] and 32 non-obese (BMI = 5-85th) admitted to the pediatric outpatient clinic. Serum triglyceride, glucose, low density lipoprotein-cholesterol, total cholesterol, high density lipoprotein-cholesterol, alanine aminotransferase, aspartate aminotransferase (AST), insulin, HbA1c levels and leptin, omentin-1, vaspin, adiponectin levels were studied. O/O children with hepatosteatosis were divided into grades 1, 2 and 3 according to the degree of hepatosteatosis determined by ultrasonography. While AST (p = 0.001), triglyceride (p = 0.006), BMI percentile (p = 0.000), HOMA index (p = 0.002), systolic blood pressure (p = 0.02), leptin (p = 0.001), omentin-1 (p = 0.001), adiponectin (p = 0.001) levels were higher, vaspin level was lower (p = 0.008) in the (O/O) group compared to the controls. There was a positive correlation between HDL and vaspin, and a negative correlation between HDL and omentin-1 in the O/O group. Also it was observed that as the degree of hepatosteotosis increased, leptin (p = 0.004), omentin-1 (p = 0.001) levels were increased. There was no significant change in vaspin level (p = 0.128). The high levels of omentin-1, leptin and adiponectin have an association with the development of hepatosteatosis in O/O children.

      • KCI등재

        Deferred invariant statistical convergence of order $\eta$ for set sequences

        Esra Gulle 호남수학회 2022 호남수학학술지 Vol.44 No.1

        In this paper, we introduce the concepts of Wijsman invariant statistical, Wijsman deferred invariant statistical and Wijsman strongly deferred invariant convergence of order $\eta$ ($0<\eta\leq 1$) for set sequences. Also, we investigate some properties of these concepts and some relationships between them.

      • KCI등재

        Levels of Salivary Sialic Acid in Children with Autism Spectrum Disorder; Could It Be Related to Stereotypes and Hyperactivity?

        Esra Demirci,Yunus Guler,Sevgi Ozmen,Mehmet Canpolat,Sefer Kumandas 대한정신약물학회 2019 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.17 No.3

        Objective: Sialic acid (Sia) is an essential nutrient for brain development, learning, memory and cognition and plays a role in neurodevelopment of infants. The aim of this study was to determine whether Sia levels are significantly associated with the autism spectrum disorder (ASD). Methods: Forty-six ASD children and 30 typically developing children aged 3 to 10 years were included in the study. Behavioral symptoms in ASD children was assessed by the Autism Behavior Checklist (AuBC), the Childhood Autism Rating Scale, and the Aberrant Behavior Checklist (ABC). After the collection of saliva samples, the supernatant was separated. All the samples kept at −80°C until Sia analysis was done. Results: Sia level was found to be significantly lower in the ASD group when compared to healthy controls (p = 0.013). There was no correlation between severity of ASD and salivary Sia levels. We found a negative correlation between AuBC scores and Sia levels and a negative correlation in both ABC Stereotypic Behavior and Hyperactivity/Noncompliance subscales with Sia levels in ASD group. Conclusion: The obtained data indicate that Sia levels could have an effect on autism-like behaviors, particularly on stereotypes and hyperactivity.

      • KCI등재

        Increased Neutrophil/Lymphocyte Ratio in Patients with Depression is Correlated with the Severity of Depression and Cardiovascular Risk Factors

        Esra Aydin Sunbul,Murat Sunbul,Omer Yanartas,Fatma Cengiz,Mehmet Bozbay,Ibrahim Sari,Huseyin Gulec 대한신경정신의학회 2016 PSYCHIATRY INVESTIGATION Vol.13 No.1

        ObjectiveaaChronic inflammation is associated with cardiovascular (CV) risk factors and psychiatric disorders. The neutrophil to lymphocyte ratio (NLR) has been investigated as a new biomarker for systemic inflammatory response. The aim of the study is to investigate the relation of NLR with severity of depression and CV risk factors. MethodsaaThe study population consisted of 256 patients with depressive disorder. Patients were evaluated with the Hamilton Rating Scale for Depression (HAM-D). Patients were classified into four groups according to their HAM-D score such as mild, moderate, severe, and very severe depression. Patients were also evaluated in terms of CV risk factors. ResultsaaPatients with higher HAM-D score had significantly higher NLR levels compared to patients with lower HAM-D score. Correlation analysis revealed that severity of depression was associated with NLR in depressive patients (r=0.333, p<0.001). Patients with one or more CV risk factors have significantly higher NLR levels. Correlation analysis revealed that CV risk factors were associated with NLR in depressive patients (r=0.132, p=0.034). In logistic regression analyses, NLR levels were an independent predictor of severe or very severe depression (odds ratio: 3.02, 95% confidence interval: 1.867–4.884, p<0.001). A NLR of 1.57 or higher predicted severe or very severe depression with a sensitivity of 61.4% and specificity of 61.2%. ConclusionaaHigher HAM-D scores are associated with higher NLR levels in depressive patients. NLR more than 1.57 was an independent predictor of severe or very severe depression. A simple, cheap white blood cell count may give an idea about the severity of depression.

      • KCI등재

        Depressive Temperament in Relatives of Patients with Schizophrenia Is Associated with Suicidality in Patients with Schizophrenia

        Esra Yazici,Zerrin Cimen,Ipen Ilknur Unlu Akyollu,Ahmet Bulent Yazici,Betul Aslan Turkmen,Atila Erol 대한정신약물학회 2018 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.16 No.3

        Objective: Suicide is a major cause of death in patients with schizophrenia; thus, predicting and preventing suicide in patients with schizophrenia is examined in various studies. Affective temperaments which are accepted as precursors of mood disorders may be an important factor in predicting suicidality. This study investigated the relationship between affective temperaments of relatives of schizophrenia patients and suicidal thoughts and other clinical correlates of patients with schizophrenia. Methods: Patients with schizophrenia and their first degree relatives are included to the study. All of the participants were evaluated with Structured Clinical Interview for DSM-IV axis I disorders and relatives with active psychiatric diagnosis were excluded. Positive and Negative Symptom Scale, Clinical Global Impression Scale, Turkish version of cognitive assessment interview were administered congruently to the patients. Relatives of the patients were evaluated with Temperament Evaluation of Memphis, Pisa, Paris and San Diego-Auto-questionnaire. Results: Depressive temperament scores of relatives of schizophrenic patients who had suicidal thoughts were higher than the scores of the relatives of the patients who did not have suicidal thoughts. Depressive temperament also predicted number of suicide attempts in regression analysis. Number of suicide attempts was also related with number of hospitalization and functionality of the patient. Conclusion: Suicidality in schizophrenia is related with relatives’ affective temperaments and patients’ own positive symptom scores. The relationship between suicidal thoughts and depressive temperament is high lightened in this study

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