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      • SCIESCOPUSKCI등재

        Marginal Zinc Deficiency Affects Biochemical and Physiological Parameters in Beef Heifer Calves

        Engle, T.E.,Nockels, C.F.,Hossner, K.L.,Kimberling, C.V.,Toombs, R.E.,Yemm, R.S.,Weaber, D.L.,Johnson, A.B. Asian Australasian Association of Animal Productio 1997 Animal Bioscience Vol.10 No.5

        A study detennined whether certain biochemical and physiological variables were altered during marginal Zn deficiency. Ten weaned crossbred Hereford Angus heifer calves, weighing $163{\pm}2kg$, were utilized. Five calves were fed a Zn - deficient (- Zn) brome-alfalfa hay diet containing 17 mg Zn/kg diet DM, and five calves were fed a Zn-adequate (+Zn) diet with 23 mg Zn/kg diet DM from $ZnSO_4$ added to the - Zn diet (total diet, 40 mg Zn/kg diet DM), for 32 d. At 21 d the - Zn calves had a reduction (p < .05) in feed efficiency. By 25 d, plasma Zn and alkaline phosphatase concentrations were reduced (p < .05) in the - Zn calves. Blood urea nitrogen, glucose, insulin, IGF-I, Cu plasma concentration and Zn and Cu concentrations of red blood cell (RBC) and liver were not altered (p > .05) by the - Zn diet through 25 d. In response to a single i. m. injection of dexamethasone (20 mg) on d 25, calves fed the two dietary Zn amounts showed no changes (p > .05) in plasma or RBC Zn and Cu concentrations, serum IGF-I, insulin, and glucose when measured at 6, 12, 24, 48, 72, and 96 h after injection. In response to an intradermal injection of phytohemagglutinin on d 30, cell mediated immune (CMI) response was reduced (p < .05) in the - Zn calves. These observations indicate that during a marginal Zn deficiency in calves, there was a decrease in feed efficiency, plasma Zn, serum alkaline phosphatase, and CMI response.

      • SCOPUSKCI등재

        X-Ray, UV and Optical Observations of Classical Cepheids: New Insights into Cepheid Evolution, and the Heating and Dynamics of Their Atmospheres

        Engle, Scott G.,Guinan, Edward F. 한국우주과학회 2012 Journal of Astronomy and Space Sciences Vol.29 No.2

        To broaden the understanding of classical Cepheid structure, evolution and atmospheres, we have extended our continuing secret lives of Cepheids program by obtaining XMM/Chandra X-ray observations, and Hubble space telescope (HST) / cosmic origins spectrograph (COS) FUV-UV spectra of the bright, nearby Cepheids Polaris, δ Cep and β Dor. Previous studies made with the international ultraviolet explorer (IUE) showed a limited number of UV emission lines in Cepheids. The well-known problem presented by scattered light contamination in IUE spectra for bright stars, along with the excellent sensitivity & resolution combination offered by HST/COS, motivated this study, and the spectra obtained were much more rich and complex than we had ever anticipated. Numerous emission lines, indicating 104 K up to ~3 x 105 K plasmas, have been observed, showing Cepheids to have complex, dynamic outer atmospheres that also vary with the photospheric pulsation period. The FUV line emissions peak in the phase range φ ≈ 0.8-1.0 and vary by factors as large as 10x. A more complete picture of Cepheid outer atmospheres is accomplished when the HST/COS results are combined with X-ray observations that we have obtained of the same stars with XMM-Newton & Chandra. The Cepheids detected to date have X-ray luminosities of log LX ≈ 28.5-29.1 ergs/sec, and plasma temperatures in the 2-8 x 106 K range. Given the phase-timing of the enhanced emissions, the most plausible explanation is the formation of a pulsation-induced shocks that excite (and heat) the atmospheric plasmas surrounding the photosphere. A pulsation-driven α2 equivalent dynamo mechanism is also a viable and interesting alternative. However, the tight phase-space of enhanced emission (peaking near 0.8-1.0 φ) favor the shock heating mechanism hypothesis.

      • KCI등재

        X-Ray, UV and Optical Observations of Classical Cepheids: New Insights into Cepheid Evolution, and the Heating and Dynamics of Their Atmospheres

        Scott G. Engle,Edward F. Guinan 한국우주과학회 2012 Journal of Astronomy and Space Sciences Vol.29 No.2

        To broaden the understanding of classical Cepheid structure, evolution and atmospheres, we have extended our continuing secret lives of Cepheids program by obtaining XMM/Chandra X-ray observations, and Hubble space telescope (HST) / cosmic origins spectrograph (COS) FUV-UV spectra of the bright, nearby Cepheids Polaris, δ Cep and β Dor. Previous studies made with the international ultraviolet explorer (IUE) showed a limited number of UV emission lines in Cepheids. The well-known problem presented by scattered light contamination in IUE spectra for bright stars, along with the excellent sensitivity & resolution combination offered by HST/COS, motivated this study, and the spectra obtained were much more rich and complex than we had ever anticipated. Numerous emission lines, indicating 104 K up to ~3 × 105 K plasmas, have been observed, showing Cepheids to have complex, dynamic outer atmospheres that also vary with the photospheric pulsation period. The FUV line emissions peak in the phase range φ ? 0.8-1.0 and vary by factors as large as 10×. A more complete picture of Cepheid outer atmospheres is accomplished when the HST/COS results are combined with X-ray observations that we have obtained of the same stars with XMM-Newton & Chandra. The Cepheids detected to date have X-ray luminosities of log LX ? 28.5-29.1 ergs/sec, and plasma temperatures in the 2-8 × 106 K range. Given the phase-timing of the enhanced emissions, the most plausible explanation is the formation of a pulsation-induced shocks that excite (and heat) the atmospheric plasmas surrounding the photosphere. A pulsation-driven α2 equivalent dynamo mechanism is also a viable and interesting alternative. However, the tight phase-space of enhanced emission (peaking near 0.8-1.0 φ) favor the shock heating mechanism hypothesis.

      • Pd(II)-Catalyzed Enantioselective C–H Activation of Cyclopropanes

        Wasa, Masayuki,Engle, Keary M.,Lin, David W.,Yoo, Eun Jeong,Yu, Jin-Quan American Chemical Society 2011 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY - Vol.133 No.49

        <P>Systematic ligand development has led to the identification of novel mono-<I>N</I>-protected amino acid ligands for Pd(II)-catalyzed enantioselective C–H activation of cyclopropanes. A diverse range of organoboron reagents can be used as coupling partners, and the reaction proceeds under mild conditions. These results provide a new retrosynthetic disconnection for the construction of enantioenriched <I>cis</I>-substituted cyclopropanecarboxylic acids.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/jacsat/2011/jacsat.2011.133.issue-49/ja207607s/production/images/medium/ja-2011-07607s_0009.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/ja207607s'>ACS Electronic Supporting Info</A></P>

      • KCI등재

        Rehabilitation of Individuals With Cancer

        Robert Samuel Mayer,Jessica Engle 대한재활의학회 2022 Annals of Rehabilitation Medicine Vol.46 No.2

        The survival rate of cancer is increasing as treatment improves. As patients with cancer now live longer, impairments may arise that impact quality of life (QOL) and function. Therefore, a focus on QOL is often as important as survival. An interdisciplinary team can achieve goal-oriented and patient-centered rehabilitation, which can optimize function and QOL, and minimize impairments, restrictions, and activity limitations. In most cases, cancer patients must be active participants in therapy and exhibit carryover. Patients with cancer often have impairments that include fatigue, pain, brain fog, impaired cognition, paresis, mood disorders, difficulty with activities of daily living (ADL), bowel/bladder/sexual dysfunction, and bone and soft tissue involvement. Adaptive equipment, exercise, and ADL training can mitigate restrictions on activity. The trajectory and phase of the disease along the continuum of cancer care may influence the goals of rehabilitation in that time window. QOL is often influenced by participation in vocational, recreational, and home-based activities. A holistic perspective should include an analysis of distress, socioeconomic barriers, and transportation limitations when addressing issues.

      • SCIESCOPUSKCI등재

        Effects of Trace Mineral Supplementation and Source, 30 Days Post-weaning and 28 Days Post Receiving, on Performance and Health of Feeder Cattle

        Dorton, K.L.,Engle, T.E.,Enns, R.M. Asian Australasian Association of Animal Productio 2006 Animal Bioscience Vol.19 No.10

        Three hundred and seventy-five steers (approximately 7 mo of age and $239.0{\pm}10.4kg$) were utilized to determine the effects of trace mineral (TM) supplementation and source on performance during the on-farm backgrounding and feedlot receiving phases of beef cattle production. At their respective ranches, steers were stratified by body weight into six groups. Groups were then assigned to one of six pens and pens were randomly assigned to treatments. Treatments consisted of: 1) control (no supplemental Cu, Zn, Mn, and Co), 2) inorganic trace mineral ($CuSO_4$, $ZnSO_4$, $MnSO_4$, and $CoCO_3$), and 3) organic trace mineral (iso-amounts of organic Cu, Zn, Mn, and Co). Mineral treatments were fed in alfalfa pellets formulated to supply 360 mg of Zn, 200 mg of Mn, 125 mg of Cu, and 12.5 mg of Co per head per day from either organic or inorganic trace mineral sources. Control steers received alfalfa pellets with no additional Cu, Zn, Mn, or Co. Steers were allowed free access to harvested alfalfa-grass hay throughout the 30-d on-farm backgrounding phase. On day 30 post-weaning, steers were weighed and transported to the feedlot. Steers were blocked by treatment within ranch, stratified by initial body weight, and randomly assigned to one of 36 pens (9-12 head per pen; 12 pens per treatment). Steers remained on the same on-farm backgrounding trace mineral treatments, however, trace mineral treatments were included in the total mixed growing ration. Steers were fed a corn silage-based growing diet throughout the 28 d feedlot receiving period. There was no effect of TM supplementation on performance of steers during the on-farm backgrounding phase. By the end of the 28-d feedlot receiving phase, ADG was similar between control and trace mineral supplemented steers. Steers supplemented with organic TM had greater (p<0.05) ADG than steers supplemented with inorganic TM by the end of the 28-d feedlot receiving phase. Morbidity and mortality rates were similar across treatments.

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