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      • KCI등재후보

        Postoperative biological and clinical outcomes following uncomplicated pancreaticoduodenectomy

        Emilie Lermite,Tao Wu,Alain Sauvanet,Christophe Mariette,Francois paye,Fabrice Muscari,Antonio Sa Cunha,Bernard Sastre,Jean-Pierre Arnaud,Patrick Pessaux 한국간담췌외과학회 2016 Annals of hepato-biliary-pancreatic surgery Vol.20 No.1

        Backgrounds/Aims: The aim of this study was to describe clinical and biological changes in a group of patients who underwent pancreaticoduodenectomy (PD) without any complication during the postoperative period. These changes reflect the “natural history” of PD, and a deviation should be considered as a warning sign. Methods: Between January 2000 and December 2009, 131 patients underwent PD. We prospectively collected and retrospectively analyzed demographic data, pathological variables, associated pathological conditions, and preoperative, intraoperative, and postoperative variables. Postoperative variables were validated using an external prospective database of 158 patients. Results: The mean postoperative length of hospital stay was 20.3±4 days. The mean number of days until removal of nasogastric tube was 6.3±1.6 days. The maximal fall in hemoglobin level occurred on day 3 and began to increase after postoperative day (POD) 5, in patients with or without transfusions. The white blood cell count increased on POD 1 and persisted until POD 7. There was a marked rise in aminotransferase levels at POD 3. The peak was significantly higher in patients with hepatic pedicle occlusion (866±236 IU/L versus 146±48 IU/L; p<0.001). For both γ-glutamyl transpeptidase and alkaline phosphatase, there was a fall on POD1, which persisted until POD 5, followed with a stabilization. Bilirubin decreased progressively from POD 1 onwards. Conclusions: This study facilitates a standardized biological and clinical pathway of follow-up. Patients who do not follow this recovery indicator could be at risk of complications and additional exams should be made to prevent consequences of such complications.

      • SCOPUSSCIEKCI등재

        Innovative customized CAD/CAM nickel-titanium lingual retainer versus standard stainless-steel lingual retainer: A randomized controlled trial

        Emilie Gelin,Laurence Seidel,Annick Bruwier,Adelin Albert,Carole Charavet 대한치과교정학회 2020 대한치과교정학회지 Vol.50 No.6

        Objective: To compare computer-aided design and computer-aided manufacturing (CAD/CAM) customized nitinol retainers with standard stainless-steel fixed retainers over a 12-month study period. Methods: This randomized controlled trial (RCT) was conducted on 62 patients randomly allocated to a control group that received stainless-steel retainers or a test group that received customized CAD/CAM nickel-titanium retainers. Four time points were defined: retainer placement (T0) and 1-month (T1), 6-month (T2), and 12-month (T3) follow-up appointments. At each time point, Little’s irregularity index (LII) (primary endpoint) and dental stability measurements such as intercanine width were recorded in addition to assessment of periodontal parameters. Radiological measurements such as the incisor mandibular plane angle (IMPA) were recorded at T0 and T3. Failure events (wire integrity or debonding) were assessed at each time point. Results: From T0 to T3, LII and other dental measurements showed no significant differences between the two groups. The data for periodontal parameters remained stable over the study period, except for the gingival index, which was slightly, but significantly, higher in the test group at T3 (p = 0.039). The IMPA angle showed no intergroup difference. The two groups showed no significant difference in debonding events. Conclusions: This RCT conducted over a 12-month period demonstrated no significant difference between customized CAD/CAM nickel-titanium lingual retainers and standard stainless-steel lingual retainers in terms of dental anterior stability and retainer survival. Both retainers eventually appeared to be equally effective in maintaining periodontal health.

      • Perceived Effectiveness of High-Fidelity Simulation in the Acquisition of the Cognitive, Psychomotor and Affective Learning in a Department of Nursing in South Korea

        Emilie M. Lopez 한국간호과학회 2021 한국간호과학회 학술대회 Vol.2021 No.10

        Aim(s): This descriptive-correlative study determined Junior & Senior nursing students’ perceived effectiveness of High-Fidelity Simulation (HFS) and assessed specific behavioral indicators in the acquisition of learning among the three domains of learning. Method(s): A total of 124 out of 166 respondents were randomly chosen after retrieval of the gathered 30-item questionnaires during the Fall and Spring Semesters, Academic Years 2016-2018 at a nursing department in the Republic of South Korea. Data were statistically treated using frequency and percentage distribution, weighted mean, Cramer’s V and Pearson’s Moment of Correlation. Result(s): Findings of the study revealed that the respondents perceived as highly effective the use of HFS in the acquisition of learning in the three domains of learning. There was a marked significant relationship that existed between the students’ perception on the effectiveness of HFS and their year level in the cognitive and affective domains, but not in the psychomotor learning domain. On the other hand, acceptance of the null hypothesis was noted between perceived effectiveness of HFS in the three domains of learning and gender variable. Conclusion(s): Majority of the female Senior Nursing students perceived HFS as highly effective in the acquisition of their learning with affective domain ranked as the highest and cognitive as the lowest. On significant relationship that was established between the variables correlated, it was more evident to have higher learning on the cognitive and affective domains of learning among Senior nursing students than the psychomotor domains. All were engaged and performed regardless of their year level and gender into the expected performance in this simulation class. For better understanding of the specific context of students’ appreciation of their learning gains in the domains of learning, succeeding study may further explore about their simulation learning experiences per se to comprehensively explain complex issues of acquisition of learning.

      • KCI등재

        Anal Dysplasia Among Patients With Multiple Human Papillomavirus Anal Lesions: Mosaic or Homogeneity?

        Emilie Lafferre,Laurent Abramowitz,Francine Walker,Dalila Benabderrhamanne,Anne Laurain,Xavier Duval,Florence Tubach 대한대장항문학회 2021 Annals of Coloproctolgy Vol.37 No.4

        Purpose: Anal dysplasia is caused by chronic infection with the human papillomavirus and exposes to the risk of anal cancer. The aim of this study was to evaluate the distribution of dysplasia anal grade among patients operated on for multiple anal condylomas with no macroscopic differences.Methods: This is a cross-sectional study of patients operated on for multiple anal condylomas including a mapping of dysplasia by performing systematically for each patient one biopsy on visible lesion from each of the 4 quadrants on anal margin and in anal canal. All biopsies were read independently by 2 different pathologists.Results: Among 72 patients, 60 were men and 48 were human immunodeficiency virus (HIV)-infected with a median age of 37.5 years. The proportion of high-grade squamous intraepithelial lesion (HSIL) was higher in the anal canal (41.7%) compared to the margin (20.8%) (P = 0.004). HSIL frequency did not differ according to the quadrant (anterior, posterior, right, and left) of the 2 areas. HSIL on anal canal was not associated with HSIL on anal margin and vice versa (P = 0.390). Neither age nor sex was associated to HSIL but HIV positivity increased the risk of HSIL on the anal margin (P = 0.010).Conclusion: Anal dysplasia is heterogeneously distributed in the anal canal as well as between anal canal and anal margin. The diagnostic of the grade of dysplasia for a person should require multiple biopsies on the canal and anal margin.

      • KCI등재후보

        Postoperative biological and clinical outcomes following uncomplicated pancreaticoduodenectomy

        Emilie Lermite,Tao Wu,Alain Sauvanet,Christophe Mariette,Francois paye,Fabrice Muscari,Antonio Sa Cunha,Bernard Sastre,Jean-Pierre Arnaud,Patrick Pessaux 한국간담췌외과학회 2016 한국간담췌외과학회지 Vol.20 No.1

        Backgrounds/Aims: The aim of this study was to describe clinical and biological changes in a group of patients who underwent pancreaticoduodenectomy (PD) without any complication during the postoperative period. These changes reflect the “natural history” of PD, and a deviation should be considered as a warning sign. Methods: Between January 2000 and December 2009, 131 patients underwent PD. We prospectively collected and retrospectively analyzed demographic data, pathological variables, associated pathological conditions, and preoperative, intraoperative, and postoperative variables. Postoperative variables were validated using an external prospective database of 158 patients. Results: The mean postoperative length of hospital stay was 20.3±4 days. The mean number of days until removal of nasogastric tube was 6.3±1.6 days. The maximal fall in hemoglobin level occurred on day 3 and began to increase after postoperative day (POD) 5, in patients with or without transfusions. The white blood cell count increased on POD 1 and persisted until POD 7. There was a marked rise in aminotransferase levels at POD 3. The peak was significantly higher in patients with hepatic pedicle occlusion (866±236 IU/L versus 146±48 IU/L; p<0.001). For both γ-glutamyl transpeptidase and alkaline phosphatase, there was a fall on POD1, which persisted until POD 5, followed with a stabilization. Bilirubin decreased progressively from POD 1 onwards. Conclusions: This study facilitates a standardized biological and clinical pathway of follow-up. Patients who do not follow this recovery indicator could be at risk of complications and additional exams should be made to prevent consequences of such complications.

      • KCI등재
      • KCI등재
      • Rare earth element distributions and fractionation in plankton from the northwestern Mediterranean Sea

        Strady, Emilie,Kim, Intae,Radakovitch, Olivier,Kim, Guebuem Elsevier 2015 CHEMOSPHERE - Vol.119 No.-

        <P><B>Abstract</B></P> <P>Rare earth element (REE) concentrations were measured for the first time in plankton from the northwestern Mediterranean Sea. The REE concentrations in phytoplankton (60–200μm) were 5–15 times higher than those in four size fractions of zooplankton: 200–500μm, 500–1000μm, 1000–2000μm and >2000μm. The concentrations within these zooplankton fractions exhibited the same ranges with some variation attributed to differences in zooplankton taxonomy. The REE concentrations in plankton were poorly related to the reported REE concentrations of seawater, but they correlated well with the calculated REE<SUP>3+</SUP>, concentrations especially with regard to middle REE (MREEs) and heavy REEs (HREEs). Plankton and seawater revealed different PAAS-normalised REE distributions, with the greatest differences observed in the light REEs. Interestingly, a comparison of PAAS-normalized sediment particles from the study of Fowler et al. (1992) showed concentrations of the same order of magnitude and a similar REE distribution without MREE enrichment. Based on this comparison, we propose a conceptual model that emphasizes the importance of biological scavenging of REEs (especially LREEs) in surface waters.</P> <P><B>Highlights</B></P> <P> <UL> <LI> REE concentrations were measured for the first time in plankton from Mediterranean Sea. </LI> <LI> REE concentrations in plankton were poorly related to the reported REE concentrations of seawater. </LI> <LI> REE concentrations in plankton correlated well with calculated free REE(III). </LI> <LI> PAAS–REE concentrations are in the same order of magnitude than PAAS-normalized sediment particles. </LI> <LI> PAAS–REE concentrations have similar distribution than PAAS-normalized sediment particles except MREE. </LI> </UL> </P>

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