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Chemical constituents and antihepatotoxic effect of the berries of Juniperus Phoenicea Part II
Maha Aboul-Ela1,*,,Nagwa El-Shaer1, and,Tarek Abd El-Azim2 한국생약학회 2005 Natural Product Sciences Vol.11 No.4
Phytochemica investigation of the berries of Juniperus phoenicea led to the isolation of 4 compounds,namely; scutellarin, isoscutellarin, shikimic acid and the new palmitoyl lactone derivative 16-hydroxy palmitic-1,16-olide. This is the first report for the occurrence of these compounds in the species grown in Libya. Theidentification of the isolated compounds was based on the application of different spectroscopic techniques. Inaddition, the antihepatotoxic effect of the aqueous decoction of the berries was investigated..
Simsek, Ela Nur,Uysal, Tuna Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.11
Apoptotic and cytotoxic activity of plant extracts obtaining from naturally growing Cynara syriaca in Turkey and cultivated C cardunculus against DLD1 colorectal cancer cells was determined. Extracts from wild and cultivated Cynara species were obtained from their vegetative parts and receptacles using hexane and applied with five different dose (0.1-1 mg/ml) as well as apigenin for MTT tests for three time periods (24, 48 and 72 hours). After cells were treated with $IC_{50}$ doses for each extract total DNA and RNA were isolated for determination of the cause of cell death. From isolated RNAs, cDNA were synthesized and amplification of p21, BCL-2 and BAX gene regions was carried out. Consequently, we found that pro-apoptotic (BAX) gene expression and a cell cycle inhibitor (p21) were induced in the presence of our artichoke extracts. In contrast, anti-apoptotic BCL-2 gene expression was reduced compared to the control group. In addition DNA fragmentation results demonstrated DLD1 cell death via apoptosis.
Sule Erten-Ela,Kasim Ocakoglu 한국공업화학회 2014 Journal of Industrial and Engineering Chemistry Vol.20 No.2
Two ruthenium complexes with carboxyl and sulfonyl groups have been synthesized, [RuII(L1)2(NCS)2]RuIIbis(4,7-diphenyl-1,10-phenanthroline-disulfonic acid disodium salt)-di(thiocyanate) [K313],[RuII(L1)2(dcbpy)] RuII bis(4,7-diphenyl-1,10-phenanthroline-disulfonic acid disodium salt)(4,40-dicarboxy-2,20-bipyridyl) [K314] as photosensitizers. UV–vis, fluorescence emission, AFM and CVmeasurements are also supplied for ruthenium complexes. Photovoltaic properties of dye sensitizednanocrystalline semiconductor solar cells based on Ruthenium complexes which bear carboxyl andsunfonyl groups have been tested under standard AM 1.5 sunlight. Under the standard global AM 1.5solar conditions, K314 and K313-sensitized solar cells demonstrate short circuit photocurrentdensities of 14.92 mA/cm2 and 11.23 mA/cm2 and overall conversion efficiencies of 5.09% and 4.02%,respectively.
Sule Erten-Ela,Magdalena Marszalek,Serpil Tekoglu,Mustafa Can,Siddik Icli 한국물리학회 2010 Current Applied Physics Vol.10 No.3
We report the synthesis, electrochemical and photovoltaic properties of triphenylamine based novel organic sensitizer, comprising donor, electron-conducting and anchoring group. Different triphenylamines were synthesized as donor unit and connected to cyano-acidic acid acceptor over vinyl group. In this work, we studied on two novel dyes (TPA2, TPA3) by attaching methyl to m-position and diphenylamine to p-position of the basic triphenylamine structure, respectively. All derivatives absorb at visible region of solar spectrum in the range of 350–632 nm. By introducing strong electron injection groups to triphenylamine ring, band gap becomes narrower while EHOMO–ELUMO levels are tuned. All current voltage (I–V)measurements were done under 100 mW/㎠ light intensity and AM 1.5 conditions. TPA3 chromophore with the lowest band gap shows the best cell performance with an efficiency (η) of 4.12%, a short-circuit photocurrent density (Isc) of 8.07 mA/㎠, an open-circuit voltage (Voc) of 714 mV and a fill factor (FF) of 0.72.
Abou El-Ela Adel A.,El-Sehiemy Ragab A.,Shaheen Abdullah M.,Shalaby Ayman S. 대한전기학회 2023 Journal of Electrical Engineering & Technology Vol.18 No.6
As the wind speed is intermittent and unpredictable, statistical distribution approaches have been used to describe wind dates. The Weibull distribution with two parameters is thought to be the most accurate way for modeling wind data. This study seeks wind energy assessment via searching for optimal parameter estimation of the Weibull distribution. For this target, several analytical and heuristic methods are investigated. The analytical methods such as maximum likelihood method, moment method, energy pattern factor method (EPFM), and empirical method (EM) are used to find these optimal parameters. Also, these parameters are obtained by four heuristic optimization algorithms called particle swarm, crow search, aquila optimizer, and bald eagle search optimizers. The simulation results of analytical and heuristics are assessed together to identify the best probability density function (PDF) of wind data. In addition, these competitive models are submitted to find the most appropriate model to represent wind energy production. In all methods, the error between actual and estimated wind energy density is computed as the target fitness function. The simulation tests are carried out based on per year real data that are collected from Zafaranah and Shark El-Ouinate sites in Egypt. Also, different indicators of fitness properties are assessed such as the root mean square error (RMSE), determination coefficient (R2), mean absolute error (MAE), and wind production deviation (WPD). The simulation results declare that the proposed bald eagle search optimization algorithm offers greater accuracy than other analytical and heuristic algorithms in estimating the Weibull parameters. Besides, statistical analysis of the compared methods demonstrates the high stability of the BES algorithm. Moreover, the BES algorithm presents the fastest convergence compared to the others. Furthermore, different models are analyzed to deduce the nonlinear relationship between the wind output power and the regarding speed where the error of wind energy density between actual and estimated is greatly minimized using the cubic model at least values of statistical indicators.
Hybrid solar cells using nanorod zinc oxide electrodes and perylene monoimide–monoanhydride dyes
Sule Erten-Ela,Sadik Cogal,Siddik Icli,Gulsah Turkmen 한국물리학회 2010 Current Applied Physics Vol.10 No.1
Hybrid solar cells have been fabricated using perylene monoimide.monoanhydride dyes with nanorod zinc oxide electrodes as electron transporting layers. We have investigated the influence of the spacer alkyl chain length of perylene monoimide.monoanhydride (PMIMA) dyes on the device performance in hybrid solar cells using nanorod zinc oxide electrodes. Nanorod zinc oxide electrodes with 50. 150 nm of diameter were synthesized in the presence of PEG400 by using microwave heating method. We observed that the dyes with longer and brunched alkyl chains exhibit higher efficiencies in hybrid solar cells. We report the highest efficiency obtained with zinc oxide nanorods under standard conditions for perylene monoimide.monoanhydride derivative with PMIMA_1 that performs 400 mV open circuit voltage, 2.81 mA/cm2 short-circuit current and 0.59% overall conversion efficiency.
Higher Expression of Toll-like Receptors 3, 7, 8, and 9 in Pityriasis Rosea
Mostafa Abou El-Ela,Rania Abdel Hay,Mohamed El-Komy,Rehab Hegazy,Amin Sharobim,Laila Rashed,Khalda Amr 대한병리학회 2017 Journal of Pathology and Translational Medicine Vol.51 No.2
Background: Pityriasis rosea (PR) is a common papulosquamous skin disease in which an infective agent may be implicated. Toll-like receptors (TLRs) play an important role in immune responses and in the pathophysiology of inflammatory skin diseases. Our aim was to determine the possible roles of TLRs 3, 7, 8, and 9 in the pathogenesis of PR. Methods: Twenty-four PR patients and 24 healthy individuals (as controls) were included in this case control study. All recruits were subjected to routine laboratory investigations. Biopsies were obtained from one active PR lesion and from healthy skin of controls for the detection of TLR 3, 7, 8, and 9 gene expression using real-time polymerase chain reaction. Results: This study included 24 patients (8 females and 16 males) with active PR lesions, with a mean age of 28.62 years. Twenty four healthy age- and sex-matched individuals were included as controls (8 females and 16 males, with a mean age of 30.83 years). The results of the routine laboratory tests revealed no significant differences between both groups. Significantly elevated expression of all studied TLRs were detected in PR patients relative to healthy controls (p < .001). Conclusions: TLRs 3, 7, 8, and 9 might be involved in the pathogenesis of PR.