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      • KCI등재

        The Cellular Architecture of the Primo Vascular System

        Fatma El-Zahraa A. Mustafa 사단법인약침학회 2022 Journal of Acupuncture & Meridian Studies Vol.15 No.1

        The primo vascular system (PVS) is of great interest to scientists in the last few years. The PVS plays a role in stem cell migration, immune function, erythropoiesis, tissue regeneration, and cancer metastasis. Discovered by Bong Han Kim in 1960, the PVS was described as a new, independent system that is distributed in the body of different animals. Since then, several cells have been discovered as important constituents of the PVS. Endothelial cells are hallmarks for the identification of the PVS, as they line the sinuses of the primo vessels and are characterized by their arrangement of rod-shaped nuclei in a parallel, broken-line fashion along the primo vessels. Immune cells as mast cells, eosinophils, neutrophils, and lymphocytes are also hallmarks for the identification of the PVS. One of the most interesting cells in the PVS are p-microcells. Primo nodes are a stem cell niche due to their p-microcells content, which express stem cell biomarkers CD133 and Oct 4. Mature erythrocytes and hematopoietic stem cells have also been observed in the PVS. Hematopoietic stem cells were observed in the PVS. Hematopoietic Stem Cells are the source of the cellular component of blood. Additionally, adrenaline and noradrenaline-producing cells, mesothelial cells, and smooth-muscle-like cells have also been described in the PVS.

      • KCI등재

        Putative Primo-Vascular System in Rabbit Placenta

        Fatma El-Zahraa A. Mustafa 사단법인약침학회 2019 Journal of Acupuncture & Meridian Studies Vol.12 No.1

        The primo vascular system (PVS) is a very important topic of study nowadays because of their role in transport and regeneration of tissue and in cell migration and cancer metastasis. The PVS was detected in different organs of the rabbit but not in the placenta. In this work, we observe the PVS inside the blood vessels of the placenta for the first time. The main characteristic features of the primo vessels (PVs) from the rabbit placenta were in agreement with the PVS in different organs of animals, including the rod-shaped nuclei and their arrangement.

      • KCI등재

        Gallbladder Paraganglioma Associated with SDHD Mutation: a Potential Pitfall on 18F-FDOPA PET Imaging

        Zahraa Abdul Sater,Abhishek Jha,Adel Mandl,Sheila K. Mangelen,Jorge A. Carrasquillo,Alexander Ling,Melissa K. Gonzales,Osorio Lopes Abath Neto,Markku Miettinen,Karen T. Adams,Pavel Nockel,Mustapha El 대한핵의학회 2019 핵의학 분자영상 Vol.53 No.2

        A 36-year-old male patient initially presented with hypertension, tinnitus, bilateral carotid masses, a right jugular foramen, and a periaortic arch mass with an elevated plasma dopamine level but an otherwise normal biochemical profile. On surveillance MRI 4 years after initial presentation, he was found to have a 2.2-cm T2 hyperintense lesion with arterial enhancement adjacent to the gallbladder, which demonstrated avidity on 68Ga-DOTATATE PET/CTand retrospectively on 18F-FDOPA PET/CT but was nonavid on 18F-FDG PET/CT. Biochemical work-up including plasma catecholamines, metanephrines, and chromogranin A levels were found to be within normal limits. This lesion was surgically resected and was confirmed to be a paraganglioma (PGL) originating from the gallbladder wall on histopathology. Pheochromocytoma (PHEO) and PGL are rare tumors of the autonomic nervous system. Succinate dehydrogenase subunit D (SDHD) pathogenic variants of the succinate dehydrogenase complex are usually involved in parasympathetic, extra-adrenal, multifocal head, and neck PGLs.We report an unusual location of PGL in the gallbladder associated with SDHD mutation which could present as a potential pitfall on 18F-FDOPA PET/CT as its normal excretion occurs through biliary system and gallbladder. This case highlights the superiority of 68Ga-DOTATATE in comparison to 18F-FDOPA and 18F-FDG in the detection of SDHD-related parasympathetic PGL.

      • KCI등재

        A 10 years-developmental study on conducting polymers composites for supercapacitors electrodes: A review for extensive data interpretation

        Ahmed El-Shahat Etman,Asmaa Mohammed Ibrahim,Fatma Al-Zahraa Mostafa Darwish,Khaled Faisal Qasim 한국공업화학회 2023 Journal of Industrial and Engineering Chemistry Vol.122 No.-

        Supercapacitors are one of the most promising technologies to meet the requirements of human sustainabledevelopment, due to their benefits such as high capacitance and rate capability, long cycle life, andlow processing cost. Electrode materials play a decisive role in the performance of supercapacitors, that’swhy many types of research on electrode materials are critical to supercapacitors. As we go forwardtoward highly flexible and bendable electronics. Conducting polymer (CP)-based materials are promisingmaterials in supercapacitors because of their unique advantages including good conductivity, flexibility,relatively cheap, easy synthesis, and so on. This review summarizes recent research progress of CPs (includingpolypyrrole (PPy), polyaniline (PANI), and polythiophene (PTh)), the CP-based composites forsupercapacitors in purpose and concentrating composites’ effect on supercapacitive parameters, besidediffusion mechanism with the calculations of supercapcitive parameters in every technique. Eventually, we give a brief outline of the development directions of CP-based supercapacitors with suggestionsfor the future of supercapacitors based on the last decade’s research.

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