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      • SCIESCOPUSKCI등재

        Robust Fuzzy Logic Current and Speed Controllers for Field-Oriented Induction Motor Drive

        El-Sousy, Fayez F.M.,Nashed, Maged N.F. The Korean Institute of Power Electronics 2003 JOURNAL OF POWER ELECTRONICS Vol.3 No.2

        This paper presents analysis, design and simulation for the indirect field orientation control (IFOC) of induction machine drive system. The dynamic performance of the IFOC under nominal and detuned parameters of the induction machine is established. A conventional proportional plus integral-derivative (PI-D) two-degree-of-freedom controller (2DOFC) is designed and analysed for an ideal IFOC induction machine drive at nominal parameters with the desired dynamic response. Varying the induction machine parameters causes a degredation in the dynamic response for disturbance rejection and tracking performance with PI-D 2DOF speed controller. Therefore, conventional controllers can nut meet a wide range of speed tracking performance under parameter variations. To achieve high- dynamic performance, a proposed robust fuzzy logic controllers (RFLC) for d-axis rotor flux, d-q axis stator currents and rotor speed have been designed and analysed. These controllers provide robust tracking and disturbance rejection performance when detuning occurres and improve the dynamic behavior. The proposed REL controllers provide a fast and accurate dynamic response in tracking and disturbance rejection characteristics under parameter variations. Computer simulation results demonstrate the effectiveness of the proposed REL controllers and a robust performance is obtained fur IFOC induction machine drive system.

      • KCI등재

        Single-use endoscopes: A narrative review

        Maged Tharwat Elghannam,Moataz Hassan Hassanien,Yosry Abdelrahman Ameen,Gamal Mohammed Elattar,Ahmed Ali El Ray,Emad Abdel Wahab Turky,Mohammed Darwish El Talkawy 소화기인터벤션의학회 2022 Gastrointestinal Intervention Vol.11 No.1

        The transmission of infections through gastrointestinal endoscopy is a vital issue. The main problem lies in the use of duodenoscopes due to mechanical aspects of the scope design. Even with high-level disinfection, sterilization of the scope can fail. Hence, the Food and Drug Administration has encouraged a shift to single-use endoscopes. Available options include endoscopes with single-use components (mainly single-use endcaps), fully single-use duodenoscopes (SUDs), and even those with a disposable elevator mechanism. Clinical trials revealed that both reusable and single-use scopes have the same efficacy, while single-use scopes have benefits in terms of infection control, economic considerations, and ease of reprocessing. A few drawbacks are left to be dealt with. Reusable duodenoscopes with removable/disposable endcaps are satisfactory except in specific situations where SUDs are better to use.

      • Different Prognostic Factors Correlate with Bcl-2 Expression among Triple Negative and Non-Triple Negative Breast Cancers

        El-Mageed, Amal Abd El-Hafez Abd,Shawky Mohamed, Abd El-Aty,Elesawy, Basem Hasan Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.2

        Background: Prognostication of breast cancer using clinico-pathologic variables, although useful, remains imperfect. Recent research has focused on finding new markers of prognosis using gene expression profiling. Panels of proteins assessed by immunohistochemistry might also be useful in this regard. This study focused on Bcl-2 protein expression in triple-negative (TNBC) and non- triple-negative breast cancer (non-TNBC) with correlation to clinico-pathologic variables. Materials and methods: We analyzed Bcl-2 expression in 77 women with primary breast carcinoma divided into two groups; triple-negative and non- triple-negative according to expression of estrogen (ER), progesterone (PR) and human epidermal growth factor receptors (Her2/neu). Bcl-2 expression was assessed in relation to age, histo-pathological subtype, grade, nodal status and tumor size. Results: Bcl-2 was expressed in 74% of triple-negative breast cancers and 70% of non- triple-negative cancers. In TNBC, expression was significantly correlated with invasive ductal subtype, while in non-TNBC it was significantly correlated with age and negative nodal status. In both groups higher Bcl-2 expression associated with favourable prognostic factors in breast cancer, but no significant statistical correlations were found. Conclusions: Frequency of Bcl-2 expression does not differ between TNBC and non-TNBC, but different prognostic factors correlate with Bcl-2 in the two cases.

      • KCI등재

        Single-use endoscopes: A narrative review

        Maged Tharwat Elghannam,Moataz Hassan Hassanien,Yosry Abdelrahman Ameen,Gamal Mohammed Elattar,Ahmed Ali El Ray,Emad Abdel Wahab Turky,Mohammed Darwish El Talkawy 소화기인터벤션의학회 2022 International journal of gastrointestinal interven Vol.11 No.1

        The transmission of infections through gastrointestinal endoscopy is a vital issue. The main problem lies in the use of duodenoscopes due to mechanical aspects of the scope design. Even with high-level disinfection, sterilization of the scope can fail. Hence, the Food and Drug Administration has encouraged a shift to single-use endoscopes. Available options include endoscopes with single-use components (mainly single-use endcaps), fully single-use duodenoscopes (SUDs), and even those with a disposable elevator mechanism. Clinical trials revealed that both reusable and single-use scopes have the same efficacy, while single-use scopes have benefits in terms of infection control, economic considerations, and ease of reprocessing. A few drawbacks are left to be dealt with. Reusable duodenoscopes with removable/disposable endcaps are satisfactory except in specific situations where SUDs are better to use.

      • KCI등재

        Immunotoxicity Following Pre- and Post-natal Aluminum Exposure in Rats

        Abd El-Azeim A. Khalaf,Ashraf M. Morgan,Mohey M. Mekawy,Maged F. Ali 한국독성학회 2008 Toxicological Research Vol.24 No.1

        The present study was designed to explore the immunotoxic effects of orally administered aluminum (Al) on pregnant rats (n = 60) and their growing fetuses and consequently on the animal wealth. The animals were randomly allocated into three equal groups of 20 rats each. The first group has no treatment and kept as a control (G1). The second and third groups of pregnant rats were treated orally with aluminum chloride at 345 ㎎/㎏ b.wt. The second group (G2) received the tested compound from the 6<SUP>th</SUP> day of gestation to the end of weaning, whereas the third group (G3) received the tested compound from the 15<SUP>th</SUP> day of gestation to the end of weaning. Control and treated animals (dams and offspring) were immunized ip with (0.5 ml) 20% sheep red blood cell (SRBC) suspension seven days before the end of experiments. At the end of exposure, ten dams and ten offspring from each group were used for assessment of cell-mediated immunity and a similar number of animals were sacrificed for evaluating the humoral immune response and serum protein profile. Aluminum chloride exposure of dams (G₂& G₃) caused significant suppression of both cell mediated and humoral immune responses in the obtained offsprings compared to the control group (G₁) without any significant effect on the immune responses of these dams. Moreover, the serum total globulins, albumin/ globulin (A/G) ratio and gamma globulin fraction were significantly decreased in the treated dam's offsprings compared to the corresponding controls while the serum total protein and all serum protein fractions showed non significant difference between the control and treated dams and between the two treated dam groups themselves. There were no histopathological changes observed in thymus, spleen and liver of the control and treated dams. Thymus of treated dam's offsprings (G2) showed lymphoid depletion in both cortex and medulla. Their spleens showed lymphoid depletion in the white pulps and congestion with hemosiderosis in the red pulps. Liver of treated dam's offsprings showed dilation and congestion of its central vein with degenerative changes in the hepatocytes. These histopathological changes were more severe in G2 than in G3 offsprings. It can be concluded that gestational and/ or lactation exposure of pregnant dams to Al chloride caused suppression of both cellular and humoral immune responses of their offsprings.

      • KCI등재

        Semen parameters on the intracytoplasmic sperm injection day: Predictive values and cutoff thresholds of success

        Alaa El din-Abdel Aal Moubasher,Emad Abdelrehim Taha,Ehab Mohamed Elnashar,Ahmed Abdel Aal Abdel Maged,Asmaa Mohamed Zahran,Heba Hassan Sayed,Hisham Diab Gaber 대한생식의학회 2021 Clinical and Experimental Reproductive Medicine Vol.48 No.1

        Objective: This study was conducted to investigate the relationship of semen parameters in samples used for intracytoplasmic sperm injection (ICSI) with fertilization and pregnancy rates in infertile couples.Methods: In this prospective study of Infertile couples with male factor infertility that had undergone ICSI, fractions of the same semen samples obtained for microinjection (to ensure the best predictability) were evaluated to determine the semen parameters and sperm DNA fragmentation index (DFI) on the day of oocyte recovery.Results: In total, 120 couples completed the study and were subdivided into fertilized (n=87) and non-fertilized couples (n=33). The fertilized couples were further classified into pregnant (n=48) and non-pregnant (n=39) couples. Compared to non-fertilized and non-pregnant couples, fertilized and pregnant couples showed statistically significantly higher sperm viability and percentage of normal sperm morphology, as well as significantly lower sperm DFI values. A receiver operating characteristic curve analysis of data from the 120 ICSI cycles showed that sperm viability, normal sperm morphology percentages, and sperm DFI were significant prognostic indicators of fertilization at cutoff values of 40%, 7%, and 46%, respectively. A sperm DFI of 46% showed sensitivity and specificity of 95% and 90%, respectively, for predicting fertilization, and no clinical pregnancies occurred in couples with a sperm DFI above 46%.Conclusion: Semen parameters from the ICSI day sample, especially sperm viability, normal morphology, and DFI, had an impact on fertilization and pregnancy outcomes in ICSI cycles.

      • KCI등재

        Constituents of Erythrina caffra Stem Bark Grown in Egypt

        Sawsan El-Masry,Hala M. Hammoda,Hala H. Zaatout,Saleh I. Alqasoumi,Maged S. Abdel-Kader 한국생약학회 2010 Natural Product Sciences Vol.16 No.4

        A new 3-indolyl propionate alkaloid; (-) abrine (1), was isolated from the alcohol extract of Erythrina caffra stem bark together with the alkaloid (-) hypaphorine (2). Phytochemical investigation of the chloroform extract led to the isolation of one fatty alcohol; 1-octacosanol, isolated for the first time from genus Erythrina, two dienoid alkaloids; erythraline and erysodine, and three isoflavonoids; 3S (+) 2'-O-methylphaseollidinisoflavan (3), (6aR, 11aR)- 3-hydroxy-10-dimethylallyl-9-methoxypterocarpan, known as sandwicensin (4) and 3R (-) erythbidin A (5). It is worth mentioning that this is the first report for the isolation of these isoflavonoids from E. caffra. The absolute configuration of 3S (+) 2'-O-methylphaseollidinisoflavan (3) was not previously reported. The isolated isoflavonoids showed promising antibacterial activity against Staphylococcus aureus. Keywords - Erythrina caffra, alkaloids, isoflavanoids, Staphylococcus aureus

      • KCI등재후보

        Anthraquinones with Antibacterial Activities from Crucianella maritima L. Growing in Egypt

        Abdalla M. El-Lakany,Maha A. Aboul-Ela,Maged S. Abdel-Kader,Jihan M. Badr,Nawal N. Sabri,Yousry Goher 한국생약학회 2004 Natural Product Sciences Vol.10 No.2

        From the extracts of Crucianella maritima L. (Rubiaceae), five new anthraquinones namely; 1-hydroxy- 2-methyl-6-methoxy anthraquinone, 6-methoxy-2-methyl quinizarin, 6-methyl-anthragallol-2,3-dimethyl ether, 6-methyl-anthragallol-2-methyl ether, and 1-hydroxy-2-carbomethoxyanthraquinone were isolated and identified. In addition, deacetyl asperulosidic acid 6'-glucoside sodium salt, a new iridoid diglucoside, along with twelve known anthraquinones, three flavonols, three sterols, and one triterpene were also isolated and identified for the first time from this plant. Their chemical structures were established by physical, chemical and spectroscopic data, including UV, MS, ID- and 2D-NMR analyses. The antimicrobial, cytotoxic activities and a preliminary clinical trial of the crude extracts and some isolates are also presented. Chemotaxonomical aspects are briefly discussed.

      • KCI등재

        Preemptive analgesic efficacy of ultrasound-guided transversalis fascia plane block in children undergoing inguinal herniorrhaphy: a randomized, double-blind, controlled study

        Abdelbaser Ibrahim,Mageed Nabil A.,El-Emam El-Sayed M.,ALseoudy Mahmoud M.,Elmorsy Mohamed M. 대한마취통증의학회 2021 Korean Journal of Anesthesiology Vol.74 No.4

        Background: Surgical repair of congenital inguinal hernia results in significant postoperative discomfort and pain. The aim of the current study was to evaluate the pre-emptive analgesic efficacy of a transversalis fascia plane (TFP) block after pediatric inguinal herniorrhaphy.Methods: Forty-four patients aged 12 to 60 months who underwent unilateral inguinal herniorrhaphy were enrolled. Four patients were excluded, and the remaining were allocated to the control group and the TFP block group. In the TFP block group, 0.4 mL/kg bupivacaine 0.25% was instilled in the plane between the transversus abdominis and transversalis fascia, while in the control group 0.9% saline was used instead of bupivacaine. The collected data were the total dose of paracetamol consumed during the first 12 h postoperatively, the postoperative Face, Leg, Activity, Cry, Consolability (FLACC) pain score, time to first use of rescue analgesia, number of patients required additional postoperative analgesics, and parents' satisfaction.Results: The median paracetamol consumption was significantly lower in the TFP block group than in the control group, and FLACC pain scores were significantly lower for all study times in the TFP block group with higher parental satisfaction scores than those for the control group. The number of patients who required additional analgesics was significantly lower in the TFP block group than in the control group. Conclusions: The use of a TFP block decreases postoperative analgesic consumption and postoperative pain intensity after pediatric inguinal herniorrhaphy. Future studies with larger sample size are required to evaluate the actual complications rate of TFP block.

      • KCI등재

        Two New Flavonol Glycosides From The Aerial Parts of Lotus lalambensis Growing in Saudi Arabia

        Hanan M. El-Youssef,Brian T. Murphy,Masouda E. Amer,Adnan J. Al-Rehaily,Maged S. Abdel-Kader,David G. I. Kingston 한국생약학회 2008 Natural Product Sciences Vol.14 No.2

        Phytochemical study of the aerial parts of Lotus lalambensis Schweinf resulted in the isolation and identification of two new flavonol glycosides; kaempferol 3-O-(5"-acetyl)-apioside-7-O-α-L-rhamnopyranoside (1) and kaempferol 3-O-α-[β-D-xylosyl-(1"" → 2")-L-rhamnopyranoside]-7-O-α-L-rhamnopyranoside (2). Structures were determined utilizing different physical, chemical, spectroscopic data including 2D-NMR experiments and HRFABMS.

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