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      • KCI등재

        El paradigma del heroe en La cuentistica de Cortazar

        ( Abeer Mohamed Abd El Hafez ) 한국스페인어문학회 2010 스페인어문학 Vol.0 No.57

        El presente trabajo procura arrojar luz sobre el paradigma del heroe en la cuentistica del escritor argentino Julio Cortazar. Los modelos protagonicos en sus cuentos presentan unos simbolos del hombre hispanoamericano en general y del argentino en particular. Por otra parte se analizara la funcion del heroe en el discurso narrativo a la luz de su poetica, basada esta en la nocion de lo fantastico entre otros muchos aspectos.

      • KCI등재

        El paradigma del héroe en la cuentística de Cortázar

        Abeer Mohamed Abd El Hafez 한국스페인어문학회 2010 스페인어문학 Vol.0 No.57

        El presente trabajo procura arrojar luz sobre el paradigma del héroe en la cuentística del escritor argentino Julio Cortázar. Los modelos protagónicos en sus cuentos presentan unos símbolos del hombre hispanoamericano en general y del argentino en particular. Por otra parte se analizará la función del héroe en el discurso narrativo a la luz de su poética, basada ésta en la noción de lo fantástico entre otros muchos aspectos.

      • SCOPUSKCI등재

        The effect of high fat dietary modification and nutritional status on the outcome of critically ill ventilated children: single-center study

        El Koofy, Nehal Mohamed,Rady, Hanaa Ibrahim,Abdallah, Shrouk Moataz,Bazaraa, Hafez Mahmoud,Rabie, Walaa Ahmed,El-Ayadi, Ahmed Ali The Korean Pediatric Society 2019 Clinical and Experimental Pediatrics (CEP) Vol.62 No.9

        Background: Ventilator dependency constitutes a major problem in the intensive care setting. Malnutrition is considered a major determinant of extubation failure, however, attention has been attracted to modulating carbon dioxide production through decreasing carbohydrate loading and increasing the percent of fat in enteral feeds. The detected interrelation between substrate oxidation and ventilation outcome became the base of several research to determine the appropriate composition of the nonprotein calories of diet in ventilated patients. Purpose: We aimed to assess the effect of high-fat dietary modification and nutritional status on ventilatory and final outcomes of pediatric intensive care. Methods: Fifty-one ventilated children (1 month to 12 years of age) with pulmonary disease who could be enterally fed, in the Cairo University Pediatric intensive care unit, were divided into 2 groups: group A included 25 patients who received isocaloric high-fat, low-carbohydrate diet; group B included 26 patients who received standard isocaloric diet. Comprehensive nutritional assessment was done for all patients. Results: Group A had a significant reduction in carbon dioxide tension, but no similar reduction in the duration or level of ventilatory support. Assisted minute ventilation was predicted by weight-for-age and caloric intake rather than the type of diet. Poor nutritional status was associated with higher mortality and lower extubation rates. Mild hypertriglyceridemia and some gastrointestinal intolerance were significant in group A, with no impact on the adequacy of energy or protein delivery. Conclusion: The high-fat enteral feeding protocol may contribute to reducing carbon dioxide tension, with mild hypertriglyceridemia and negligible gastrointestinal intolerance as potential adverse effects. Optimization of nutritional status rather than dietary modification may improve ventilatory and survival outcomes in critically ill-ventilated children.

      • Different Prognostic Factors Correlate with Bcl-2 Expression among Triple Negative and Non-Triple Negative Breast Cancers

        El-Mageed, Amal Abd El-Hafez Abd,Shawky Mohamed, Abd El-Aty,Elesawy, Basem Hasan Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.2

        Background: Prognostication of breast cancer using clinico-pathologic variables, although useful, remains imperfect. Recent research has focused on finding new markers of prognosis using gene expression profiling. Panels of proteins assessed by immunohistochemistry might also be useful in this regard. This study focused on Bcl-2 protein expression in triple-negative (TNBC) and non- triple-negative breast cancer (non-TNBC) with correlation to clinico-pathologic variables. Materials and methods: We analyzed Bcl-2 expression in 77 women with primary breast carcinoma divided into two groups; triple-negative and non- triple-negative according to expression of estrogen (ER), progesterone (PR) and human epidermal growth factor receptors (Her2/neu). Bcl-2 expression was assessed in relation to age, histo-pathological subtype, grade, nodal status and tumor size. Results: Bcl-2 was expressed in 74% of triple-negative breast cancers and 70% of non- triple-negative cancers. In TNBC, expression was significantly correlated with invasive ductal subtype, while in non-TNBC it was significantly correlated with age and negative nodal status. In both groups higher Bcl-2 expression associated with favourable prognostic factors in breast cancer, but no significant statistical correlations were found. Conclusions: Frequency of Bcl-2 expression does not differ between TNBC and non-TNBC, but different prognostic factors correlate with Bcl-2 in the two cases.

      • No Association between BRCA1 Immunohistochemical Expression and Tumor Grade, Stage or Overall Survival in Platinum-Treated Epithelial Ovarian Cancer Patients

        Shawky, Abd El-Aty,El-Hafez, Amal Abd,El-Tantawy, Dina,Hamdy, Rasha Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.10

        Background: The aim of this work is to assess the frequency of BRCA1 protein immunohistochemical (IHC) expression in epithelial ovarian cancer (EOC) and to evaluate the association of BRCA1 expression with clinical and pathological characteristics and the overall survival (OS) of patients treated with postoperative platinum-based chemotherapeutic agents. Materials and Methods: This retrospective study was conducted on 35 cases of epithelial ovarian cancer selected from the files of the Pathology Department, Faculty of Medicine, Mansoura University, Egypt. Immunohistochemistry (IHC) was performed for BRCA1 gene protein. BRCA1 expression was compared to patient's age, tumor histology, grade, stage and OS time. Statistical analysis was carried out with the SPSS version 16.0 to assess significant associations. Results: BRCA1 nuclear expression was detected in 40% of EOC, in which a mild increase in the percentage of positive cases was observed with serous histology, stage IV, and grade 3 carcinomas. There was a significant statistical difference in BRCA1 expression with regard to histological subtypes of EOC (p=0.048), but not grade or stage. Mean OS and survival rate were slightly better for BRCA1 expressing group, but there was no statistically significant difference (p=0.528). Conclusions: No association between BRCA1 immunohistochemical expression and tumor grade, stage or overall survival was noted in platinum-treated epithelial ovarian cancer patients.

      • KCI등재

        The effect of high fat dietary modification and nutritional status on the outcome of critically ill ventilated children: single-center study

        Nehal Mohamed El Koofy,Hanaa Ibrahim Rady,Shrouk Moataz Abdallah,Hafez Mahmoud Bazaraa,Walaa Ahmed Rabie,Ahmed Ali El-Ayadi 대한소아청소년과학회 2019 Clinical and Experimental Pediatrics (CEP) Vol.62 No.9

        Background: Ventilator dependency constitutes a major problem in the intensive care setting. Malnutrition is considered a major determinant of extubation failure, however, attention has been attracted to modulating carbon dioxide production through decreasing carbohydrate loading and increasing the percent of fat in enteral feeds. The detected interrelation between substrate oxidation and ventilation outcome became the base of several research to determine the appropriate composition of the nonprotein calories of diet in ventilated patients. Purpose: We aimed to assess the effect of high-fat dietary modification and nutritional status on ventilatory and final outcomes of pediatric intensive care. Methods: Fifty-one ventilated children (1 month to 12 years of age) with pulmonary disease who could be enterally fed, in the Cairo University Pediatric intensive care unit, were divided into 2 groups: group A included 25 patients who received isocaloric high-fat, low-carbohydrate diet; group B included 26 patients who received standard isocaloric diet. Comprehensive nutritional assessment was done for all patients. Results: Group A had a significant reduction in carbon dioxide tension, but no similar reduction in the duration or level of ventilatory support. Assisted minute ventilation was predicted by weight-for-age and caloric intake rather than the type of diet. Poor nutritional status was associated with higher mortality and lower extubation rates. Mild hypertriglyceridemia and some gastrointestinal intolerance were significant in group A, with no impact on the adequacy of energy or protein delivery. Conclusion: The high-fat enteral feeding protocol may contribute to reducing carbon dioxide tension, with mild hypertriglyceridemia and negligible gastrointestinal intolerance as potential adverse effects. Optimization of nutritional status rather than dietary modification may improve ventilatory and survival outcomes in critically ill-ventilated children.

      • KCI등재

        Subclinical Hypothyroidism Is Independently Associated with Microalbuminuria in a Cohort of Prediabetic Egyptian Adults

        Mervat M. El-Eshmawy,Hala A. Abd El-Hafez,Walaa Othman El Shabrawy,Ibrahim A. Abdel Aal 대한당뇨병학회 2013 Diabetes and Metabolism Journal Vol.37 No.6

        Background: Recent evidence has suggested an association between subclinical hypothyroidism (SCH) and microalbuminuria in patients with type 2 diabetes. However, whether SCH is related to microalbuminuria among subjects with prediabetes has not been studied. Thus, we evaluated the association between SCH and microalbuminuria in a cohort of prediabetic Egyptian adults. Methods: A total of 147 prediabetic subjects and 150 healthy controls matched for age and sex were enrolled in this study. Anthropometric measurements, plasma glucose, lipid profile, homeostasis model assessment of insulin resistance (HOMA-IR),thyroid stimulating hormone (TSH), free thyroxine, triiodothyronine levels, and urinary albumin-creatinine ratio (UACR) were assessed. Results: The prevalence of SCH and microalbuminuria in the prediabetic subjects was higher than that in the healthy controls (16.3% vs. 4%, P<0.001; and 12.9% vs. 5.3%, P=0.02, respectively). Prediabetic subjects with SCH were characterized by significantly higher HOMA-IR, TSH levels, UACR, and prevalence of microalbuminuria than those with euthyroidism. TSH level was associated with total cholesterol (P=0.05), fasting insulin (P=0.01), HOMA-IR (P=0.01), and UACR (P=0.005). UACR was associated with waist circumference (P=0.01), fasting insulin (P=0.05), and HOMA-IR (P=0.02). With multiple logistic regression analysis, SCH was associated with microalbuminuria independent of confounding variables (β=2.59; P=0.01). Conclusion: Our findings suggest that prediabetic subjects with SCH demonstrate higher prevalence of microalbuminuria than their non-SCH counterparts. SCH is also independently associated with microalbuminuria in prediabetic subjects. Screening and treatment for SCH may be warranted in those patients.

      • KCI등재
      • KCI등재

        Improvement of Soft Organic Clay Soil Using Vertical Drains

        Walid El Kamash,Kamal Hafez,Mahmoud Zakaria,Azza Moubarak 대한토목학회 2021 KSCE JOURNAL OF CIVIL ENGINEERING Vol.25 No.2

        The design of foundations based on soft clay is still a very challenging problem. Three experimental cases were performed to examine the action of soft clay: the first case without drains, the second case with sand drains and the third case with prefabricated vertical drains (PVDs). Two-dimensional finite element analysis was carried out using PLAXIS 2D and its findings were compared to previous experimental results where good consistency was found. Parametric study was conducted with a variation in the size, length and diameter of sand drains. The length and spacing of the PVD, the diameter of the smear zone and the permeability of the smear zone were also studied. Results have shown that PVD is preferable to the improvement of soft clay rather than sand drainage systems. The sand drains decreased the time of 90% consolidation by (90.8%) using 50 cm diameter, 2 m spacing and 25 m length, and the PVDs decreased the time of 90% consolidation by (94.4%) using 4 mm × 10 cmdimensions, 2 m spacing and 25 m length. Both sand drains and PVD are effective in decreasing the consolidation time. The results of this paper concluded analytical formula that indicate the percentage of wick drain consolidation.

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