Cytomegalovirus Infection among Pregnant Women in Beijing: Seroepidemiological Survey and Intrauterine Transmissions

( Qing`e Jin ),( Jianrong Su ),( Shanna Wu ) 한국미생물 · 생명공학회 2017 Journal of microbiology and biotechnology Vol.27 No.5

Primary cytomegalovirus (CMV) infection during pregnancy can cause congenital defects. Available data for CMV infection during pregnancy in north China are inadequate. The aim of this study was to evaluate the epidemiology of maternal CMV infection and explore the incidence of congenital infection. In this prospective study, serum CMV IgG and IgM antibodies were measured in 2,887 pregnant women using ELISA, and the IgG avidity test was performed on all IgM-positive subjects. The seroprevalence of anti-CMV IgG was 94.70%, and of anti-CMV IgM was 1.28%. CMV IgG prevalence increased significantly with age (p < 0.01). Women living in downtown areas showed higher IgG prevalence than those residing in urban areas (p = 0.023). CMV-IgM seroprevalence was highest in autumn (p = 0.021). There was no difference in IgM seroprevalence by age, socioeconomic status, geographical area, or gravida. The rate of primary CMV infection was 0.45% (13/2,887) at the first trimester. The seroconversion rate during pregnancy was 0.76% (22/2,887). One woman underwent seroconversion during pregnancy and gave birth to an infant with asymptomatic CMV infection. Congenital CMV infection was diagnosed in five of the 14 infants from 14 mothers with active infection, for a vertical transmission rate of 35.71% (5/14). Three infants were asymptomatic, whereas two infants presented symptomatic infection with hearing deficits. Although CMV IgG prevalence is relatively high in north China, significant attention to primary CMV infection during pregnancy is still needed.

Association between extreme temperature and kidney disease in South Korea, 2003–2013: Stratified by sex and age groups

Kim, Ejin,Kim, Ho,Kim, Yong Chul,Lee, Jung Pyo Elsevier 2018 Science of the Total Environment Vol.642 No.-

<P><B>Abstract</B></P> <P>Weather conditions due to climate change affect the health directly and indirectly. Previous studies have shown associations with temperature, heat wave, and cold spell, and these do not only result in mortality from cardiovascular disease, respiratory disease, etc., but also in morbidity. This study aimed to quantify the relative risk for hospital admissions related to ambient temperature for genitourinary system diseases, which are representative of metabolic disease. We conducted a nationwide retrospective cohort study using claims data generated by medical services for diseases of the urinary system. The data was based on medical claims data from 16 districts in South Korea, to the nationwide level between 2003 and 2013. A total of 1,255,671 hospital admissions through the emergency department because of diseases of the genitourinary system were reported within the study period. The overall cumulative relative risk at the 99th percentile vs. the minimum morbidity percentile for renal diseases was 1.252 (95% confidence interval 1.211 to 1.294) in Seoul, 1.252 (1.21 to 1.296) in Busan, 1.236 (1.196 to 1.276) in Daegu, 1.237(1.197 to 1.279) in Gwangju, and 1.258 (1.218 to 1.299) in Gyeonggi-do, 1.278 (1.211 to 1.349) in Chungcheongbuk-do, 1.291 (1.235 to 1.35) in Gyeongsangnam-do. In the group of men over 65 years, the overall cumulative RR was high and statistically significant in acute kidney injury (AKI). But we could not find the effect of high temperature for chronic kidney disease (CKD). The association were rather opposite, but not statistically significant. Our nationwide study not only demonstrates relative risk considering lag effects associated with ambient temperature and trends in hospital admissions through the emergency department for genitourinary disorders but also observed differences among disease groups.</P> <P><B>Highlights</B></P> <P> <UL> <LI> We observed an association between high temperature and hospital admissions of kidney diseases in South Korea. </LI> <LI> The effect on acute kidney injury hospitalization was significant, but the effect on chronic kidney disease was not. </LI> <LI> We found interactions between gender and age in the association between kidney morbidity and high temperature. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

5G 환경을 위한 네트워크 기반의 분산 이동성 관리 프로토콜

김이진(Ejin Kim),최형기(Hyoung-Kee Choi) 한국통신학회 2018 한국통신학회 학술대회논문집 Vol.2018 No.1

Effects of residential greenness on clinical outcomes of patients with chronic kidney disease: a large-scale observation study

( Jae Yoon Park ),( Jiyun Jung ),( Yong Chul Kim ),( Hyewon Lee ),( Ejin Kim ),( Yon Su Kim ),( Ho Kim ),( Jung Pyo Lee ) 대한신장학회 2021 Kidney Research and Clinical Practice Vol.40 No.2

Background: As industrialization and urbanization are accelerating, the distribution of green areas is decreasing, particularly in developing countries. Since the 2000s, the effects of surrounding greenness on self-perceived health, including physical and mental health, longevity, and obesity have been reported. However, the effects of surrounding green space on chronic kidney disease are not well understood. Therefore, we investigated the impact of residential greenness on the mortality of chronic kidney disease patients and progression from chronic kidney disease to end-stage renal disease (ESRD). Methods: Using a large-scale observational study, we recruited chronic kidney disease patients (n = 64,565; mean age, 54.0 years; 49.0% of male) who visited three Korean medical centers between January 2001 and December 2016. We investigated the hazard ratios of clinical outcomes per 0.1-point increment of exposure to greenness using various models. Results: During the mean follow-up of 6.8 ± 4.6 years, 5,512 chronic kidney disease patients developed ESRD (8.5%) and 8,543 died (13.2%). In addition, a 0.1-point increase in greenness reduced all-cause mortality risk in chronic kidney disease and ESRD patients and progression of chronic kidney disease to ESRD in a fully adjusted model. The association between mortality in ESRD patients and the normalized difference vegetation index was negatively correlated in people aged >65 years, who had normal weight, were nonsmokers, and lived in a nonmetropolitan area. Conclusion: Chronic kidney disease patients who live in areas with higher levels of greenness are at reduced risk of all-cause mortality and progression to ESRD.

Psychiatric Sequelae of Former “Comfort Women,” Survivors of the Japanese Military Sexual Slavery during World War II

Jeewon Lee,YoungSook Kwak,YoonJung Kim,EunJi Kim,EJin Park,Yunmi Shin,BunHee Lee,SoHee Lee,HeeYeon Jung,Inseon Lee,JungIm Hwang,Dongsik Kim,Soyoung Irene Lee 대한신경정신의학회 2018 PSYCHIATRY INVESTIGATION Vol.15 No.4

“Comfort women” refers to young women and girls who were forced into sexual slavery by the Imperial Japanese military during World War II. They were abducted from their homes in countries under Imperial Japanese rule, mostly from Korea, and the rest from China, Philippines, Malaysia, Taiwan, Indonesia, the Netherlands, etc. “Comfort women” endured extreme trauma involving rape, sexual torture, physical abuse, starvation, threats of death, and witnessed many others being tortured and killed. This article reviews all the studies that have investigated the psychiatric or psychosocial sequelae of the survivors of the Japanese military sexual slavery. Most importantly, a recent study which conducted a psychiatric evaluation on the former “comfort women” currently alive in South Korea is introduced. The participants’ unmarried rate was relatively high and their total fertility rate was relatively low. Majority of the participants reported having no education and being the low economic status. They showed high current and lifetime prevalence of posttraumatic disorder, major depressive disorder, somatic symptom disorder, social anxiety disorder, panic disorder, and alcohol use disorder. Participants showed high suicidality and majority of the participants still reported being ashamed of being former “comfort women” after all these years. This article highlights the fact that the trauma has affected the mental health and social functioning of former “comfort women” throughout their lives, and even to the present day.

호스트 기반 분산형 이동성 관리 기술에서 안전하고 효과적인 바인딩 업데이트

이세영(Seyeong Lee),최형기(Hyoung-Kee Choi),김이진(EJin Kim) 한국정보보호학회 2017 정보보호학회논문지 Vol.27 No.2

모바일 트래픽이 급격히 증가함에 따라 모바일 기기가 끊김 없이 통신하기 위한 이동성 관리 기술로써 DMM(Distributed Mobility Management)이 제안되었다. DMM은 코어 네트워크에서 엣지 네트워크로 이동성 관리를 분산하여 낮은 지연으로 안정적인 바인딩 업데이트를 가능하게 한다. 그러나 DMM 시스템에는 여전히 네트워크상의 지연 문제와 세션에 대한 보안상의 문제가 존재한다. 본 논문에서는 기존 DMM 시스템에 존재하는 문제점을 지적하고, 이를 해결하기 위해 MN (Mobile Node)이 직접 인증에 참여하여 올바른 상호 인증이 이루어지는 새로운 프로토콜을 제안한다. 또한, 성능 분석을 통해 보안상의 향상뿐만 아니라 성능상의 향상이 존재함을 확인하였다. As mobile traffic increases rapidly, DMM (Distributed Mobility Management) has been proposed as a mobility management technology for seamless communication of mobile devices as mobile traffic increases rapidly. the DMM distributes mobility management from the core network to the edge network, enabling stable binding updates with low latency. However, the DMM still have network delay and security problems for sessions. In this paper, we point out the problems existing in the DMM and propose a new protocol in which the MN (Mobile Node) directly participates in authentication and mutual authentication is correctly performed to solve this problem. We demonstrate not only security improvements but also performance improvements with performance analysis