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- 저자 : Dujian (검색결과 4 건)
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Dynamic process: international diversification and innovation performance from emerging economies
Du Jian,Zheng Qiuxia,Chang Xiaoran 기술경영경제학회 2020 ASIAN JOURNAL OF TECHNOLOGY INNOVATION Vol.28 No.2
Drawing upon the transaction cost economics and organizational learning theory, this study examines how international diversification affects firm's innovation performance. With a longitudinal data set obtained from a sample of 73 Chinese firms in information communication equipment manufacturing industry, home appliances manufacturing industry, and low voltage apparatus and cable manufacturing industry, we find a curvilinear inverted S-shaped relationship between international diversification and innovation performance. It implies that emerging enterprises might gain increase at the expansion stage, experience a hard time at the conflict stage, and then reap again at the convergence phase.
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Du Jian,Ding Sasa 기술경영경제학회 2019 ASIAN JOURNAL OF TECHNOLOGY INNOVATION Vol.27 No.3
From the phenomenon-driven perspective, on the basis of data from Thomson Reuters Web of ScienceTM database covering a period of 29 years (January 1990 to August 2019), this study employs bibliometric and content analyses to evaluate the research state of the internationalization and innovation relationship. This study is to assist internationalization scholars in positioning their research more explicitly and encourage them to deeply think about which approach and theoretical mechanisms best fit their research questions and designs.
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Silence of LncRNA GAS5 Protects Cardiomyocytes H9c2 against Hypoxic Injury via Sponging miR-142-5p
Du, Jian,Yang, Si-Tong,Liu, Jia,Zhang, Ke-Xin,Leng, Ji-Yan Korean Society for Molecular and Cellular Biology 2019 Molecules and cells Vol.42 No.5
The regulatory role of long noncoding RNA (lncRNA) growth arrest-specific transcript 5 (GAS5) in both cancerous and noncancerous cells have been widely reported. This study aimed to evaluate the role of lncRNA GAS5 in heart failure caused by myocardial infarction. We reported that silence of lncRNA GAS5 attenuated hypoxia-triggered cell death, as cell viability was increased and apoptosis rate was decreased. This phenomenon was coupled with the down-regulated expression of p53, Bax and cleaved caspase-3, as well as the up-regulated expression of CyclinD1, CDK4 and Bcl-2. At the meantime, the expression of four heart failure-related miR-NAs was altered when lncRNA GAS5 was silenced (miR-21 and miR-142-5p were up-regulated; miR-30b and miR-93 were down-regulated). RNA immunoprecipitation assay results showed that lncRNA GAS5 worked as a molecular sponge for miR-142-5p. More interestingly, the protective actions of lncRNA GAS5 silence on hypoxia-stimulated cells were attenuated by miR-142-5p suppression. Besides, TP53INP1 was a target gene for miR-142-5p. Silence of lncRNA GAS5 promoted the activation of PI3K/AKT and MEK/ERK signaling pathways in a miR-142-5p-dependent manner. Collectively, this study demonstrated that silence of lncRNA GAS5 protected H9c2 cells against hypoxia-induced injury possibly via sponging miR-142-5p, functionally releasing TP53INP1 mRNA transcripts that are normally targeted by miR-142-5p.
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Two-dimensional water seepage monitoring in concrete structures using smart aggregates
Zou, Dujian,Li, Weijie,Liu, Tiejun,Teng, Jun Techno-Press 2018 Structural monitoring and maintenance Vol.5 No.2
The presence of water inside concrete structures is an essential condition for the deterioration of the structures. The free water in the concrete pores and micro-cracks is the culprit for the durability related problems, such as alkali-aggregate reaction, carbonation, freeze-thaw damage, and corrosion of steel reinforcement. To ensure the integrity and safe operation of the concrete structures, it is very important to monitor water seepage inside the concrete. This paper presents the experimental investigation of water seepage monitoring in a concrete slab using piezoelectric-based smart aggregates. In the experimental setup, an $800mm{\times}800mm{\times}100mm$ concrete slab was fabricated with 15 SAs distributed inside the slab. The water seepage process was monitored through interrogating the SA pairs. In each SA pair, one SA was used as actuator to emit harmonic sine wave, and the other was used as sensor to receive the transmitted stress wave. The amplitudes of the received signals were able to indicate the water seepage process inside the concrete slab.
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