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      • 저밀도 폴리에틸렌에서 불순물 혼합량에 따른 트리진전과 방전펄스와의 관계 연구

        姜道烈,朴懷俊,金正洙 弘益大學校 1982 弘大論叢 Vol.14 No.2

        It is well known that, when enough high voltage is applied to a high-voltage cable with an insulator, treeing phenomenon can occur due to void or impurities such as dust, metal powder, etc. inside the insulator. Also,it is known that this treeing phenomenon drastically shortens the life of the insulator. In this paper, we investigate the effects of the mixture ratio of impurities to the Low-Density Polyethylene used as an insulator on the treeing phenomenon based on the electrical characteristics. As impurity samples, Al₂O₃ and SiO₂with the particle diameter of 44μm have been used for different weight mixture ratios of 1%, 5%, and 10%, respectively. Since the treeing phenomenon occurring in the sample, based material of Low-Density Polye thylene mixed with 1% impurity can easily be observed with an optical microscope, we have first investigated the relationship between the result measured from electrical characteristics and the one obtained from observation with an optical microscope. Specifically, it has been found that the total number of pulses measured from the eletrical waveform of the treeing phenomenon is closely related with the growth length of the tree observed with an optical microscope. Based on these results, the growth length of the tree for the other sample materials with 5% and 10% impurities could be estimated from the total number of the electrical tree pulses for these sample materials, respectively. As a result, it has been found that the effect of the treeing phenomenon decreases as the mixture ratio increases. Also, it is shown that the total number of the electrical tree pulses makes it possible to predict the effect of the treeing phenomenon without observing with an optical microscope.

      • 국내 보건소의 모기방제 업무에 관한 실태 및 개선방안

        이동규,김현두 고신대학교 보건과학연구소 2006 보건과학연구소보 Vol.16 No.-

        A study was performed on the status of the mosquito control work of the local public health centers (LPHCs) of Korea. The 42.8% of the personnel for the mosquito control works were composed of officers and local residents, but 17.0% of them were officers of the LPHCs. Only 16.9% of the LPHCs gave a higher priority to mosquito larval control, and 27.0% of the LPHCs surveyed mosquitoes to analyze control effects after treatment. At accomplishment of mosquito control program, 21.4% and 49.1% of the LPHCs performed all and a half of the control work, respectively. The 51.6% of LPHCs sprayed insecticides only when they received residential's civil appeals of mosquito problems without any surveillance. Only 22.9% of LPHCs controlled mosquito larvae and 4.7%of them used mud loach fishes as mosquito predators. The mosquito adult control was performed using residual spraying (48.0%), thermal fogging (39.1%) and light traps (14.6%). The 67.9% of LPHCs had information about location of cattle sheds for mosquito control in their districts. For insecticide storage, they used warehouses (64.2%), basements (23.9%), container boxes (8.2%), and rooms in LPHCs (1.9%). The 70.4% of the LPHCs introduced the new advanced control methods to their residential using brochures and/or other materials. The amount of the budgets for pest control was an average of 229 million Wons in each LPHC. The personnel expenses (38.5%) and purchase of pesticides (28.6%) were the highest in the budgets. The 24% of LPHCs committed mosquito control to PCOs. For advanced mosquito control, the personnel need to be educated regularly, and they have to follow the mosquito control manual and their control programs.

      • SCIESCOPUSKCI등재

        Cytochrome P450 2E1 Activity in a Korean Population

        Dou-Hyun Muhn,Ji-Min Chae,Jae-Yong Bahn,Hae-Jung Song,Hyung-Kee Kim,Jun-Tack Kwon,Dong-Ryul Sohn 대한생리학회-대한약리학회 1997 The Korean Journal of Physiology & Pharmacology Vol.1 No.5

        <P> Cytochrome P450 2E1 (CYP2E1) is involved in the toxicity and carcinogenicity of a number of solvents and xenobiotics. Like the various types of oxidation pharmacogenetics, the activity of the enzyme shows a discernible interindividual and interethnic variation. However, no pharmacogenetic information on CYP2E1 polymorphism has been available from a Korean population. The aim of this study was to explore the pharmacogenetics of CYP2E1 polymorphism in a native Koreans after an oral 400 mg dose of chlorzoxazone administered to 128 subjects. Urine samples were collected during the subsequent 8-hour period and urinary concentrations of chlorzoxazone and 6-hydroxychlorzoxazone were determined by a high performance liquid chromatography with an ultraviolet detector. The limit of detection in the samples was found to be 0.5 μg/ml. The mean value of the 6-hydroxychlorzoxazone excreted in 8 hr urine expressed as the percentage was 48.2 13.8%. The frequency distribution of percentage of the administered dose excreted as the 6-hydroxy metabolite was unimodally distributed in the subjects studied. However, the values showed wide (7-fold) interindividual difference, ranged from 11.6% to 79.8% of the dose of chlorzoxazone. Thus, it was considered that the pharmacogenetic characteristics of CYP2E1 in a Korean population did not represent multimodal distribution in the 6-hydroxychlorzoxazone excreted in 8-hr urine expressed as the percentage. And the activity of the CYP2E1 in a Korean population seemed to be less compared with that of the Caucasian subjects.

      • KCI등재
      • SCIESCOPUSKCI등재

        Cytochrome P450 2E1 Activity in a Korean Population

        Muhn, Dou-Hyun,Chae, Ji-Min,Bahn, Jae-Yong,Song, Hae-Jung,Kim, Hyung-Kee,Kwon, Jun-Tack,Sohn, Dong-Ryul The Korean Society of Pharmacology 1997 The Korean Journal of Physiology & Pharmacology Vol.1 No.5

        Cytochrome P450 2E1 (CYP2E1) is involved in the toxicity and carcinogenicity of a number of solvents and xenobiotics. Like the various types of oxidation pharmacogenetics, the activity of the enzyme shows a discernible interindividual and interethnic variation. However, no pharmacogenetic information on CYP2E1 polymorphism has been available from a Korean population. The aim of this study was to explore the pharmacogenetics of CYP2E1 polymorphism in a native Koreans after an oral 400 mg dose of chlorzoxazone administered to 128 subjects. Urine samples were collected during the subsequent 8-hour period and urinary concentrations of chlorzoxazone and 6-hydroxychlorzoxazone were determined by a high performance liquid chromatography with an ultraviolet detector. The limit of detection in the samples was found to be $0.5\;{\mu}g/ml$. The mean value of the 6-hydroxychlorzoxazone excreted in 8 hr urine expressed as the percentage was 48.2 13.8%. The frequency distribution of percentage of the administered dose excreted as the 6-hydroxy metabolite was unimodally distributed in the subjects studied. However, the values showed wide (7-fold) interindividual difference, ranged from 11.6% to 79.8% of the dose of chlorzoxazone. Thus, it was considered that the pharmacogenetic characteristics of CYP2E1 in a Korean population did not represent multimodal distribution in the 6-hydroxychlorzoxazone excreted in 8-hr urine expressed as the percentage. And the activity of the CYP2E1 in a Korean population seemed to be less compared with that of the Caucasian subjects.

      • SCOPUSKCI등재

        에크린 나선종 4예

        윤두희(Dou Hee Yoon),김시용(Si Yong Kim),조상현(Sang Hyun Cho),허동(Dong Houh),조백기(Baik Kee Cho) 대한피부과학회 1995 대한피부과학회지 Vol.33 No.1

        Eccrine spiradenoma is a txnign, painful tumor of the skin, which probably originates in the coil of the eccrine sweat glands and presents a characteristic clinical and pa.hological picture. However recently, the weakness and inconsistency of the enzymes histochemican, actions and electron microscopic findings, and the presence of numerous undifferentiated and indetirn, inate cells suggest a rather low degree of differentiation. We present herein four cases of eccrine spiradenoma which show livrse histopat.hologic characteristics including typical rosette-like structure, ductal structure, vacuar structure and mixed type, respectively. This report may support the premise that eccrine spiridinoma is defived not only from the eccrine duct but also from pluripotential stem cells. (Kor J Dermatol 995; 33<1): 140-144)

      • SCOPUSKCI등재

        비전형적인 광택 태선

        윤두희 ( Dou Hee Yoon ),조상현 ( Sang Hyun Cho ),김시용 ( Si Yong Kim ),조백기 ( Baik Kee Cho ) 대한피부과학회 1995 대한피부과학회지 Vol.33 No.4

        Lichen nitidus, characterized by its typical clinical and histopathologic findings, is an uncomrnon chronic dermatosis of unknowned etiology. The distribution of this disease is most often localized, but in some cases it may becorne generalized. Some authors suggested that lichen nitidus is a variant of lichen planus in terms of its coincidence, ultrastructural and immunophenot,ypic studies. We report herein a case of lichen nitidus which presents dark brown linear, grouped, or confluent papules on the face, cheat, and upper extremities, accompanying with the histopathologic findings of pigmentary incontirence in the portion of claw clutching a ball appearance. This report suggests that lichen nitidus shows hyperpigmentation clinically and could be one of the dermatoses which exhibit pigmentavy incontinence in a histopathologic study. (Kor J Dermatol 1995;33(4): 794-797)

      • SCOPUSKCI등재

        경결홍반과 동반된 구진괴사성 결핵진 1예

        김진우,이현정,오신택,윤두희 대한피부과학회 1999 대한피부과학회지 Vol.37 No.11

        We report a rare case in which two tuberculids, erythema induratum and papulonecrotic tuberculid, occured together. A 15-year-old Korean girl had two types of clinically distinct lesions; painful subcutaneous nodules on the legs and pruritic necrotic papules on the trunk and extremity. Mantoux test showed a strong positive reaction. Histopathologic findings of the subcutaneous nodule and necrotic papule were consistent with erythema induratum and papulonecrotic tuberculid, respectively. There was no extracutaneous focus of tuberculosis. Polymerase chain reaction for tuberculosis bacilli in both lesions revealed negative results. Antituberculous therapy brought a rapid clinical improvement of lesions within a month.

      • SCIESCOPUSKCI등재

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