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      • 工事區間의 交通流 特性

        金東寧 단국대학교 1995 論文集 Vol.29 No.-

        Traffic flow characteristics of workzones for uninterrupted flows is studied. Maximum flow rates (capacity) and lane distribution are investigated through field studies for oversaturated flows in Korea. The major findings are as follows ; 1. Decrease rates of capacity comparing with basic freeway segments are 28% from 2 lanes to 1 lane and 13% from 4 lanes to 3 lanes. 2. The capacity impacts of lane drop for 2 lanes are bigger than those for 4 lanes. But the impacts are not proportional to the number of lanes.

      • 交叉路 飽和交通容量算定에 관한 比較硏究

        金東寧 단국대학교 1986 論文集 Vol.20 No.-

        The Calculation of capacity for an intersection is very important for the analysis of urban transportation problems. As intersection capacity is based on the concept of saturation flow rate, the process of calculatiting it should be verified through any manner in Korea. Saturation flow rate calculated on the basis of HCM will be compared with the observed values for four intersections in Seoul and the difference will be analyzed and evaluated. The passenger car unit(pcu) for buses around intersection will be analyzed also in this study.

      • 교차로 성능개선을 위한 화폭차로 길이의 기준설정

        김동녕,이승환 단국대학교 1999 論文集 Vol.34 No.-

        This paper is studied to find the method for increasing capacity of intersection and decreasing queue length, delay by improving geometric design of intersection under heavy delay. Especially, guidelines about auxiliary lanes at flared intersections which could be applied to road design are proposed for each different roadway and traffic conditions(cycle length, green time, demand of volume) Simulation, model was used for determining the length of auxiliary lanes at flared intersections. A useful graph about the suitable length of auxiliary lanes to be applied was made from this research. The proper auxiliary lanes at flared intersection effect on the capacity of intersection considerably.

      • KCI등재

        고려 충선왕대 지방제도의 개편

        최동녕(Choi, Dong-Nyeong) 호서사학회 2020 역사와 담론 Vol.0 No.95

        본 논문은 1308년(충선왕 복위)과 1310년에 이루어진 일련의 지방제도 개편 과정을 검토하는 데 목적이 있다. 『고려사』 지리지의 누락된 연혁 기사를 보완해서 정리한 결과 당시 개편에는 邑格이 중요한 변수로 작용했음을 알 수 있었다. 1308년에 신설된 14牧은 도호부 7곳과 지주부군 7곳에서 승격한 지역이었다. 목 이하의 단위 가운데 읍격이 높은 곳을 우선 선정하되, 그밖에 道 단위의 규모를 고려하면서 실질적인 지방의 읍세 등을 반영한 조치였다. 이로써 전국에는 전체 25개의 목을 운영하게 되었고, 계수관을 늘려 대규모 영역 분할을 단행하였다. 또 1308년~1310년 동안 檢校宰臣에 해당하는 고위 관원들이 牧使로 파견되었다. 당시 관부를 병합하고 관원을 축소하는 정치적 분위기와 맞물려 고위 관원들을 감축하면서 25목에는 大臣들이 나가 대대적인 田民計點 사업과 각종 지방 행정에 대한 강력한 집행력을 발휘하였다. 그러나 불과 2년 만인 1310년에 ‘汰諸牧’ 조치가 이루어져 본래의 읍격이 지닌 상하 관계에 맞추어 재조정되었다. 그러므로 기존에 목과 대도호부였던 곳은 그대로 목으로 유지되고, 신설된 14목이 都護府와 유사한 府로 강등되었다. 읍격의 조정 과정을 통해 고려 전기에 京・牧・大都護府 > 都護府 > 知州府郡 > 縣(令)으로 이어지는 서열이 충선왕대 이후로는 府・牧 > 知府 > 知州郡 > 縣(令)으로 전환된 것이다. 또한 결과적으로 지주부군 7곳은 새롭게 부각되어 부로 승격되었고, 지역적 여건에 따라서는 계수관으로 설정되기도 하였다. 하지만 이와 같은 일련의 정비로 전국적인 계수관제의 변화가 수반된 것은 아니었다. The purpose of this study is to examine the serial process of reorganizing the local system in 1308(Reinstatement of King Chungseon) and 1310. The result from supplementing and organizing the be missing history on Goryeosa(高麗史) Jiriji(地理志) showed that Eupkyuk(邑格) was an important variable at the moment of reorganization. The 14 Mok(牧)s were regions which were promoted from 7 Dohobu(都護府) regions and 7 Jijubugun(知州府郡). The actual local taxation was reflected by selecting the regions with higher grade among units below Mok unit first and considering the scale in do unit. As a result, total of 25 Moks were operated in the whole country. A large-scale division of areas was carried out by increasing the number of Gaesugwan(界首官). Also, in 1308 to 1310, high-ranking government officials who applicable to Geomgyojaeshin(檢校宰臣) were sent as Moksa(牧使). In response to the political climate of merging government offices and reducing government officials, the number of high-ranking government officials also reduced. This led Daeshin(大臣) to be sent on 25 Moks and they had powerful executive force on local administration such as participating on Jeonmingyejeom(田民計點) project. However, as ‘Taejeomok(汰諸牧)’ took place in 1310 after 2 years, it was readjusted based on the existing upper-lower relationship of the Eupkyuk. As a result, existing mok and Daedohobu(大都護府) were maintained as Mok while the newly established 14 Moks were degraded to Bu(府) similar to Dohobu. The grade of Gyeong(京), Mok, Daedohobu > Dohobu > Jijubugun > Hyunryeong(縣令) in early Goryeo Dynasty period changed to Bu, Mok > Jibu > Jijugun > Hyunryeong after the time of King Chungseon through the process of adjusting Eupkyuk. Although such serial organization did not involve changes on the national Gaesugwan system, newly rising regions were practically raised and some of them were set as Gaesugwan depending on the local conditions.

      • HCV, Alcoholic : O-019 ; Lipoic acid prevents the changes of intracellular lipid partitioning by free fatty acid

        ( Dong Chan Kim ),( Dae Won Jun ),( Tae Yeob Kim ),( Joo Hyun Sohn ),( Sang Pyo Lee ),( Kang Nyeong Lee ),( Hang Lak Lee ),( Oh Young Lee ),( Byung Chul Yoon ),( Ho Soon Choi ) 대한간학회 2012 춘·추계 학술대회 (KASL) Vol.2012 No.1

        Background: Recently, the composition of lipid in liver is more important than the total amount of lipid in NAFLD. Methods: To evaluate the effect of lipoic acid (LA) on lipotoxicity and on the intracellular lipid partitioning, HepG2 was cultured with palmitic acid (PA) or LA. We used TUNEL assay for apoptosis, mitochondrial DNA copy number for mitochondrial function, electromicroscopy for the structure of the mitochondria, fluorescent microscope for the ROS activity, gaschromatography for lipid partitioning. Results: PA significantly increased apoptosis of the cell line (0.5% vs. 19.5%, p<0.05), and LA significantly suppressed apoptosis (19.5% vs. 1.6%, p<0.05). The number of mitochondrial DNA copy was decreased in PA group, and recovered after adding LA (Control: PA: PA+LA= 553± 33.8: 291±14.55: 421±21.05 copies). Electromicroscopy showed significant difference between the groups. ROS activity was significantly increased in the PA group, and decreased in LA group (4180 vs. 4350 vs. 4220 relative fluorescence unit respectively, p<0.05). LA decreased the proportion of saturated fatty acid and increased the proportion of unsaturated fatty acid. Free cholesterol was showed on the cell membrane in LA group. But in PA group, they located in the cytoplasm and cell membrane. Conclusions: LA prevented FFA-induced hepatic lipotoxicity via reversal intracellular lipid composition.

      • KCI등재

        ORiginal Article : The Effect of DA-6034 on Intestinal Permeability in an Indomethacin-Induced Small Intestinal Injury Model

        ( Dong Shin Kwak ),( Oh Young Lee ),( Kang Nyeong Lee ),( Dae Won Jun ),( Hang Lak Lee ),( Byung Chul Yoon ),( Ho Soon Choi ) 대한간학회 2016 Gut and Liver Vol.10 No.3

        Background/Aims: DA-6034 has anti-inflammatory activities and exhibits cytoprotective effects in acute gastric injury models. However, explanations for the protective effects of DA-6034 on intestinal permeability are limited. This study sought to investigate the effect of DA-6034 on intestinal permeability in an indomethacin-induced small intestinal injury model and its protective effect against small intestinal injury. Methods: Rats in the treatment group received DA-6034 from days 0 to 2 and indomethacin from days 1 to 2. Rats in the control group received indomethacin from days 1 to 2. On the fourth day, the small intestines were examined to compare the severity of inflammation. Intestinal permeability was evaluated by using fluorescein isothiocyanate-labeled dextran. Western blotting was performed to confirm the association between DA-6034 and the extracellular signal-regulated kinase (ERK) pathway. Results: The inflammation scores in the treatment group were lower than those in the control group, but the difference was statistically insignificant. Hemorrhagic lesions in the treatment group were broader than those in the control group, but the difference was statistically insignificant. Intestinal permeability was lower in the treatment group than in the control group. DA-6034 enhanced extracellular signal-regulated kinase expression, and intestinal permeability was negatively correlated with ERK expression. Conclusions: DA-6034 may decrease intestinal permeability in an indomethacin-induced intestinal injury model via the ERK pathway. (Gut Liver 2016;10:406-411)

      • SCIESCOPUSKCI등재

        The Differences in Prevalence and Sociodemographic Characteristics of Irritable Bowel Syndrome According to Rome 2 and Rome 3

        ( Dong Won Park ),( Oh Young Lee ),( Sung Gon Shim ),( Dae Won Jun ),( Kang Nyeong Lee ),( Hye Young Kim ),( Hang Lak Lee ),( Byung Chul Yoon ),( Ho Soon Choi ) 대한소화기기능성질환·운동학회 2010 Journal of Neurogastroenterology and Motility (JNM Vol.16 No.2

        Background/Aims: Irritable bowel syndrome (IBS) is one of the most frequently observed disorders by primary care and practitioners. The aim of this study was to estimate the prevalence of IBS using the Rome II and III criteria in the general Korean population and also to compare sociodemographic differences between subjects diagnosed by these criteria. Methods: Telephone interview surveys were performed with a total of 1,009 individuals in Korea, 15 years of age or older. The questionnaire, based on the Rome II and III criteria, was validated. Results: Among the 1,009 subjects, the prevalence of IBS was 8.0% under the Rome II criteria (81 subjects; 6.4%, male; 9.6%, female), and 9.0% (91 subjects; 7.0%, male; 11.0%, female) under the Rome III criteria. The accordance rate of Rome II and III was 73.5%. Both groups showed highest frequency in the age of 30s (13.9% vs. 15.3% respectively). Female subjects showed a higher prevalence than male subjects under Rome III (91 subjects; 11.0% in female, 7.0% in male; p < 0.05), but not under Rome II criteria. Many patients older than 50 years were added when analyzed under the Rome III criteria, but not under the Rome II criteria (p = 0.017). Conclusions: The Rome III criteria were Less restrictive and showed good agreement with the Rome II criteria. The prevalence of IBS was increased in young women.(J Neurogastroenterol Motil 2010;16:186-193)

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