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The Estimation of Breast Cancer Disease-Probability by Difference of Individual Susceptibility
Sue Kyung Park,Keun-YoungYoo,DaeHeeKang,Sei-HyunAhn,Dong-YoungNoh,Kuk-JinChoe 대한암학회 2003 Cancer Research and Treatment Vol.35 No.1
Purpose: The aims were to evaluate the main riskfactors (RFs) of breast cancer and to estimate the individualdisease-probability from combinations of RFs inKorean female.Materials and Methods: We conducted case-controlstudy of 1,687 incident cases of invasive carcinoma and1,238 controls during 1996∼2000. A breast cancer disease-probability model was established by a generalmodeling process using a multivariate logistic regressionmodel, which included the main Korean RFs and synergisticinteraction-terms.Results: The main Korean RFs selected were age,family history of second relatives, BMI, age at first fulltermpregnancy, breast-feeding, and a special test on thebreasts. Two synergisms were observed between age andbreast-feeding, and between special test and age at firstfullterm pregnancy. The disease-probability and modelare shown in Table 4, and Appendix 1.Conclusion: The availability of previous Western modelswas limited for Korean female due to the differencesinhazard-rates and the characteristics of breast cancerbetween Asian and Western females. Due to limited basicdata, i.e. incidence, hazard-rate and cancer-cohorts, thedeveloping-probability of breast cancer for Korean femaleswas not calculated. Therefore, the disease-probabilitywas calculated instead. This approach might bemore beneficial for Koreans, and help in the decisionmakingfor regular screening or hospital visit-interval,counseling in breast-cancer clinics, prescribing high-riskpopulation, and in educating for primary prevention, althoughit over-estimates the relative probability comparedto the developing-probability and the 65% predictivevalidity. (Cancer Res Treat. 2003;35:35-51)
IDO 최적화 MDF 방법을 적용한 파워요트 선형 최적화 연구
안동현(Dong ?Hyun Ahn),이필립(Philippe Lee),신종계(Jong-Gye Shin) (사)한국CDE학회 2014 한국 CAD/CAM 학회 학술발표회 논문집 Vol.2014 No.2
For the purpose of automating the design process, by the analyse of existing case of IDO methodology, method that can be applied to the design optimization was studied. According to the classification criteria of MDF IDO belongs to a single structure type. MDF, belonging to the single-structure IDO is the most basic and intuitive, with a form. In this study, the MDF methodology is applied to the power yacht hull design, and constitutes a optimization process. Configures the structure of the system level optimizer and each subspace level optimizer, and the details of implementing the whole system can be established the optimization framework.