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      • KCI등재

        󰡔다신전(茶神傳)󰡕의 출전(出典)

        유동훈(Dong-Hun Yoo) 한국차학회 2017 한국차학회지 Vol.23 No.2

        In previous studies, as the textual source for Dashinjeon, Kim Myeong-bae recommended using Jeungbomanbojeonseo, the Buddhist Monk Yongun Gyeongdangjeungjeongmanbojeonseo, and Park Dong-choon of the transcription of Manbojeonseo which was supplemented, modified, and complemented while it was being made. In this study, it was carefully checked both Jeungbomanbojeonseo and Gyeongdangjeungjeongmanbojeonseo, which were thought of as textual sources for Dashinjeon in previous studies, against the original Dayegwanbon Dashinjeon and determined which of these two printings is the textual source for Dashinjeon. The comparison of Jeungbomanbojeonseo and Gyeongdangjeungjeongmanbojeonseo showed that Dayegwanbon Dashinjeon contained less misspelled and omitted letters than Jeungbomanbojeonseo. Also, after checking it against the original, it was determined that Dashinjeon was not supplemented, modified or complemented while writing it out, but was a fair transcript of the original Jeungbomanbojeonseo. Therefore, this paper determined Jeungbomanbojeonseo to be the textual source for Dashinjeon.

      • KCI등재후보

        사각근 증후군 환자의 경추 부정렬에 관한 연구

        강지훈 ( Ji Hun Kang ),이길준 ( Kil Joon Lee ),박영회 ( Young Hoi Park ),금동호 ( Dong Ho Keum ) 한방재활의학과학회 2006 한방재활의학과학회지 Vol.16 No.4

        Objectives : We investigated the possibility of cervical spine misalignment caused by Scalenus anticus syndrome to find out the Scalenus anticus syndrome could effect misalignment of cervical spine. Methods : 18 patients with Scalenus anticus syndrome who attended Dept. of Oriental Rehabilitation Medicine, College of Oriental Medicine, Dong-guk University from 20th June to 10th September 2006, were involved in the investigation. After researching misalignment through neutrality lateral, flexion lateral, extension lateral x-ray examination views, we measured difference of length of cervical spine misalignment. We analyzed the difference of length of cervical spine misalignment, and the relationship among the neutrality lateral, flexion lateral and extension lateral position. Results : Lateral flexion and lateral extension position were shown higher frequency than neutrality position in cervical spine misalignment. We got the statistical significance in the difference of length of cervical spine misalignment by position changes, it showed that C3, C4 vertebra bodies in lateral neutrality position, C2, C3, C4, C5 vertebra bodies in flexion lateral position, C3-5 vertebra bodies in extension lateral position. Conclusions : It was considered that scalenus anticus syndrome could increase cervical spine misalignment which could be a factor of making in cervical spine disease.

      • KCI등재

        추나수기요법과 자침으로 호전된 만성 미골통 환자

        강지훈 ( Ji Hun Kang ),김대필 ( Dae Feel Kim ),박영회 ( Young Hoi Park ),금동호 ( Dong Ho Keum ) 한방재활의학과학회 2005 한방재활의학과학회지 Vol.15 No.3

        Objectives : This study was performed to evaluate the effect of Chuna manipulation and acupuncture treatment on coccygodynia clinically. Methods : The patients were hospitalized Dept. of Oriental Rehabilitation Medicine, College of Oriental Medicine, Dong-Guk University, diagnosed as Chronic coccygodynia and treated with Chuna Manipulation, Acupuncture. After measured the VAS(visual analogue scale), we analyzed effect of chuna manipulation and acupuncture treatment on coccygodynia. Result & Conclusions : Symptom of patient such as coccygodynia was improved after above treatment. So it is suggested that oriental medical treatment are effective in the coccygodynia.

      • SCOPUSKCI등재

        In vivo transduction of ETV2 improves cardiac function and induces vascular regeneration following myocardial infarction

        Lee, Sunghun,Lee, Dong Hun,Park, Bong-Woo,Kim, Riyoun,Hoang, Anh Duc,Woo, Sang-Keun,Xiong, Wenjun,Lee, Yong Jin,Ban, Kiwon,Park, Hun-Jun Nature Publishing Group UK 2019 Experimental and molecular medicine Vol.51 No.2

        <▼1><P>Vascular regeneration in ischemic hearts has been considered a target for new therapeutic strategies. It has been reported that ETV2 is essential for vascular development, injury-induced neovascularization and direct cell reprogramming of non-endothelial cells into endothelial cells. Thus, the objective of this study was to explore the therapeutic potential of ETV2 in murine models of myocardial infarction in vivo. Direct myocardial delivery of lentiviral ETV2 into rodents undergoing myocardial infarction dramatically upregulated the expression of markers for angiogenesis as well as anti-fibrosis and anti-inflammatory factors in vivo. Consistent with these findings, echocardiography showed significantly improved cardiac function in hearts with induced myocardial infarction upon ETV2 injection compared to that in the control virus-injected group as determined by enhanced ejection fraction and fractional shortening. In addition, ETV2-injected hearts were protected against massive fibrosis with a remarkable increase in capillary density. Interestingly, major fractions of capillaries were stained positive for ETV2. In addition, ECs infected with ETV2 showed enhanced proliferation, suggesting a direct role of ETV2 in vascular regeneration in diseased hearts. Furthermore, culture media from ETV2-overexpressing cardiac fibroblasts promoted endothelial cell migration based on scratch assay. Importantly, intramyocardial injection of the adeno-associated virus form of ETV2 into rat hearts with induced myocardial infarction designed for clinical applicability consistently resulted in significant augmentation of cardiac function. We provide compelling evidence that ETV2 has a robust effect on vascular regeneration and enhanced cardiac repair after myocardial infarction, highlighting a potential therapeutic function of ETV2 as an efficient means to treat failing hearts.</P></▼1><▼2><P><B>Cardiovascular disease: New hope for healing the heart</B></P><P>A gene therapy strategy that stimulates cardiovascular repair could improve recovery for heart attack patients. Heart attacks inflict severe damage on the heart and blood vessels, tissues with limited capacity for self-repair. Researchers led by Kiwon Ban of the City University of Hong Kong and Hun-Jun Park of the Catholic University of Korea, Seoul, have now demonstrated that a gene responsible for cardiovascular development can also efficiently stimulate heart repair. They used viruses to deliver the gene into a mouse model of heart attack, and showed that treated heart tissues exhibited strong recovery relative to untreated controls. The treatment reduced scar tissue formation and promoted proliferation of the cells lining blood vessels and blood vessel formation, measurably improving heart function. This approach could lay the groundwork for treating a common potentially fatal event.</P></▼2>

      • SCIESCOPUSKCI등재
      • 3-Acetamidophenyl Acetate의 Fries Rearrangement 반응 연구

        김동현, 만노즈 마니캄, 풀라레디 보꾸, 이상윤, 조정석, 정상헌 충남대학교 약학대학 의약품개발연구소 2017 藥學論文集 Vol.32 No.-

        Fries rearrangement has been known as highly useful reaction for the synthesis of ortho-or para-hydroxyacylbenzene from phenyl ester in the presence of Lewis acid catalyst. Conventionally, aluminum chloride was used as catalyst. For obtaining N-(4-acetyl-3-hydroxyphenyl)acetamide, 3-acetamidophenyl acetate was subjected to Fries Rearrangement reaction using aluminum chloride. Although the desired N-( 4-acetyl-3-hydroxyphenyl)acetamide was obtained, yield was very low. In addition, regioisomer N-(2-acetyl-5-hydroxyphenyl)acetamide and unexpected N-(2-methyl-4-oxo-4H-chromen-7-yl) acet-amide were obtained. NMR study and conversion to known compollnds confirmed the substitlltion pattern of these phenylacetamides and the structure of chromen-4-ones. Under this Fries Rearrangement condition, formation of chromen-4-one was newly discovered.

      • MRC 결합의 레이크 수신기에서 채널 추정 알고리즘의 성능분석

        오동진,나철훈 국립7개대학공동논문집간행위원회 2005 공업기술연구 Vol.5 No.-

        In this paper, we analyze channel estimation algorithms in a RAKE receiver with MRC. There are 3 popular channel estimation algorithms, which are WMSA(Weighted Multi-Slot Averaging) algorithm, EGE(Equal Gain Estimation) algorithm. and SSE(Symbol-to-Symbol Estimation) algorithm. We analyze asynchronous IMT-2000(3GPP) which employ 3 different channel estimation algorithms by using MATLAB. We used jakes fading channel model for the analysis. From simulation results, we could observe that the performance of WMSA algorithm is better than others in low Doppler effect(3km/h). However, in the case of high Doppler effect(120km/h), the EGE algorithm is more efficient. In this case the simple estimator with EGE algorithm seems to be more useful.

      • 一部 小兒바이러스性 肝炎의 臨床·疫學的 考察

        李庭勳,柳東俊 慶熙大學校 1987 論文集 Vol.16 No.-

        A Clinico-epidemiologic study was performed on 150 children with viral hepatitis who had been admitted in pediatric department of Dong-San Sacred Heart Hospital from January 1984 to December 1985.

      • KCI등재

        고농도 용액의 침지시 감자 절편의 탈수모델에 관한 연구

        최동원,신해헌 한국식품영양학회 1999 韓國食品營養學會誌 Vol.12 No.6

        감자절편를 고농도용애에 침지하여 탈수시킨 결과 침지용액을 구성하는 용질의 분자량에 따라 탈수 형태가 다르게 나타났다. 저분자 용액 인 NaCl. PEG 400 용액에 침지만 경우 조직의 뒤틀림현상(cytorrhysis)은 나타나지 않고 부피의 감소와 수분의 탈수현상이 나타난 반면 고분자 용액인 PEG 4000, PEG 6000용액에 침지한 경우cytorrhysis 현상을 동반한 부피의 감소와 탈수현상이 나타났다. 초기 탈수속도는 저분자용액에 침지시 더 빨랐으나 최종 탈수량은 고분자 용액에 침지시 더 컸다. 고장성 용액에 감자절편을 침지시켜 탈수되는 기작이 두가지 압력(삼투압, 분자압착력)에 의해 진행된다고 가정하고 모델을 제안하여 검정한 결과 제안된 모델은 고분자 용액에 침지시의 탈수현상을 설명하는데 적합하였다 모델에서 구해진 압력인자(ΔP)와 농도인자(a)는 온도(T)와 농도(C)의 함수로 표현되며 계수의 탄력성 검정결과 농도에대한 의존성이 더 큰 것으로 나타났다. To investigate the effect of molecular size of solute of solution where which potato slices were soaked. In the case of soaking in low molecular solution like NaCl and polyethylene glycol(PEG)400 solution only plasmolysis was observed. However in high molecular solution like PEG4000 and PEG6000, cytorrhysis was observed. Initial dewatering rate was faster when soaked in low molecular solution but total amount of removed water was larger in high molecular solution. Suggested model fitted well dewatering phenomena when soaked in high molecular solution. Pressure factor and concentration factor was more dependent on concentration of soaking solution than soaking temperature.

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