施肥條件이 사탕무의 生育과 Betacyanin 含量에 미치는 影響

金度勳,朴賢眞,金賢勍,鄭大守 東亞大學校生命資源科學大學附設 農業資原硏究所 1996 農業生命資援硏究 Vol.5 No.1

사탕무의 生育과 betacyanin 含量의 變化에 대한 施肥條件의 影響을 알아보기 위하여 室素 0, 10, 15 및 20㎏/10a와 加里 0, 10, 15 및 20㎏/10a 處理하여 試驗한 結果는 다음과 같다. 草長과 葉數는 室素 15㎏/10a 處理區까지는 增加되었으나, 20㎏/10a 處理區에서는 오히려 減少되었으며, 根直徑과 根長도 室素 施用量의 增加에 따른 有意的인 差異가 認定되었다. 그리고 根重은 無處理區에 비해 室素 處理區에서 增加되었으나, 室素 處理區間에는 큰 差異를 나타내지 않았다. Betacyanin 含量은 室素 15㎏/10a와 加里 20㎏/10a 處理區에서 0.126%로 가장 높았고, 生育段階別로는 파종후 110日에 가장 높은 含量을 나타내었다. These experiments were carried out to investigate the effect of nitrogen and potassium application on growth and betacyanin content of sugar beet. The experiments were respectively treated with 0, 10, 15 or 20㎏/10a nitrogen and 0, 10, 15 or 20㎏/10a of postassium, and the results were summarized as fellows. Plant height and number of leaves were increased by 15㎏/10a of nitrogen, otherwise; it was decreased by 20㎏/10a of nitrogen. There were significant differences root diameter and root length by increament of nitrogen application. Root weight was progressively increased by nitrogen treatments compared to the control, although there was no significant differences among the amount of nitrogen treatments. Betacyanin content was high 0.126% in the plot treated with 15㎏/10a of nitrogen and 20㎏/10a of potassium respectively. For the growth stage the corresponding value showed the highest level at the 110th day after seeding.

植物 生長調整劑의 處理가 水稻幼苗의 蛋白質 含量 및 酵素 活性에 미치는 影響

金度勳,金賢勍,鄭大守 東亞大學校 1996 東亞論叢 Vol.33 No.-

A study was carried out to investigate the effect of growth regular on protein content, PAL and peroxidase activity in rice seedling plants, Akibare, a Japonica type variety. ABA(0.1, 1, 10ppm), 2.4-D(10, 100, 1000ppm), and GA(0.05, 0.5, 5ppm) were respectively treated for 5 days to the nee seedling plants which were grown for 20 days. The results were summarized as follows. In stems, the protein content showed the highest value in the plot treated with GA for 5 days, although ABA and 2.4-D treated plots showed no significant differences compared with the control. PAL activity in the plot treated with GA for 5 days and in the plot treated with 2.4-D for 10 days were respectively higher than control. On the contrary, it was low in the plot treated with ABA. PAL activity in roots was respectively higher in the plots treated with GA for 5days and 2.4-D for 10 darts than the control. According to increment of days seedling growth, peroxidase activity was respectively maintained in the plot treated with ABA, 2.4-D, and GA, although it was decreased in the control.

참께 種實의 成熟過程에 따른 脂質 및 脂肪酸組成의 變化

김도훈 東亞大學校生命資源科學大學附設 農業資源硏究所 1995 農業生命資援硏究 Vol.4 No.1

참깨 種實의 成熟에 따른 構成脂質의 變化와 각 脂質의 脂肪酸 組成 變化를 調査한 結果, 蛋白質과 脂質의 含量은 開花 後 30日까지 直線的인 增加를 보여, 開花 後 40日에 80㎎/g, 240㎎/g의 含量을 나타냈다. 中性脂質의 構成 成分은 TG가 60% 內外로 가장 많았고, 登熟의 進展에 따른 增加의 폭이 매우 컸다. 總脂質, 中性脂質, 隣脂質 및 糖脂質의 脂肪酸 組成은 飽和脂肪酸인 stearic acid와 palmitic acid의 成熟의 進展에 따라 계속 減少하여 開花後 40日에 9.63~12.88%와 7.35~19.10%를 나타냈고, 반면 不飽和脂肪酸인 oleic acid와 linoleic acid는 成熟의 進展에 따라 계속 增加하여 開花後 40日에 28.44∼40.11%와 43.80∼44.39%를 보였다. 그리고 隣脂質의 경우 다른 脂質에 비해 oleic acid가 開花後 40日에 28.44%로 가장 낮았고, 糖脂質에 있어서는 palmitic acid가 開花後 15日까지 增加하는 것이 脂質과는 다른 傾向이었다. This study was conducted to investigate changes in protein and total lipid contents, fatty acid compositions of total lipid, triglrceride, phospholipid and glycolipid in sesame seed during maturation. Protein and total lipid contents were increased rapidly during 30 days after flowering(DAF) and were 80㎎/g and 240㎎/g at 40 DAF, respectively. In compositions of neutral lipid, triglyceride content was extremely plenty of about 60% and increased rapidly during maturation. In fatty acid compositions of total lipid, neutral lipid, phospholipid and glycolipid, stearic acid and palmitic acid were decreased during maturation and were 9.63∼12.88% and 7.35∼19.10% at 40 DAF, respectively, However, oleic acid and linoleic acid were increased during maturation and were 28.44∼40.11% and 23.80∼44.39% at 40 DAF, respectively. In phospholipid, oleic acid was 28.44% at 40 DAF which was lower than other lipid. In glycolipid, palmitic acid was increased to 15 DAF, and it was different tendence from other lipid.

栽培法의 差異가 水稻의 收量 및 米質에 미치는 影響

정원복,김도훈,정대수,김현경 東亞大學校附設 農業生命科學硏究所 1999 農業生命資援硏究 Vol.8 No.1

水稻의 早期栽培에 따른 品種別 栽植距離와 株當苗數가 生育 및 收量에 미치는 影響과 栽培時期에 따른 米質을 변화를 比較코저 小白벼, 農白벼, 福光벼, 道奉벼, 太白벼, 및 伽倻벼를 公試하여 實施한 試驗結果는 다음과 같다. 株當穎花數는 穎植(27×17cm)며 株當 3苗植인 處理區에서 가장 많았고, 10a當 收量은 密植(27×13cm) 및 株當 5∼7苗植인 處理區에서 가장 많았다. 10a當 收量 및 藁重, 穗數間에 有意的인 正의 相關關係가 認定되었다. 또한 Amylose含量은 普通期栽培보다 早期栽培에서 적게 나타났고, 品種間에는 福光벼가 가장 낮았고, Alkali崩壞度는 普通期栽培보다 早期栽培에서 낮았고, 品種間에는 伽倻벼가 높게 나타났다. A study was presented to analyze rice quality and to number of seedlings per hill and their spacing on growth and yield in various varieties of early planted rice; Sobeag, Nongbeag, Dobong, Taebeag and Gaya. There was a higher number of spikelets in wide spacing than in narrow spacing, and the number from from 3 seedlings per hill was greater than the one from 5 or 7 seedlings per hill. In grain yield per 10 areas, there was a higher yield in narrow spacing than in wide spacing, and the on from the block of the 5 or 7 seedlings per hill was greater than the one from the block of 3 seedlings per hill. There was a significant positive correlation among grain yield per 10 areas, straw weigh and the number of panicles. Amylose contents were lower in early planted rice than in ordinarily planted rice. The Boggawng variety showed lowest amylose contents among the varieties used in this experiment. Alkali digestibility values were lower in early planted rice than in ordinarily planted rice. The Gaya variety showed highest alkali digestibility values among the varieties used in this experiment.

工團 周邊 農耕地 土壤의 成分 變化에 관한 硏究

鄭大守,金度勳,金賢勍 東亞大學校 1995 東亞論叢 Vol.32 No.-

溫山工業團地 造成에 따른 土壤汚染의 정도를 調査하기 위하여 1988年부터 1994年까지 7년간에 걸쳐 工團 隣近地域의 논과 밭 土壤에 대한 土壤成分의 理化學的인 變化를 調査分析한 結果를 要約하면 다음과 같다. 土壤의 pH 變化는 논과 밭 土壤 모두 每年 pH가 약간씩 減少하여 土壤 酸性化가 深化되어지고 있으며, 一部 地域에서는 pH 5.0 以下의 强酸性을 나타내는 곳도 있었다. 논 土壤의 特性變化에서는 有機物含量과 有效燐酸의 含量은 全國平均보다 낮았으며, Ca++이온과 Mg++이온의 含量은 每年 增加하는 傾向이었다. 밭 土壤의 特性變化에서도 有機物含量과 有效燐酸의 含量은 全國平均보다 낮게 나타났으며, K이온은 全體 平均이 0.85me/100g으로 全國平均 0.5m3/100g보다도 높은 含量을 보였고, Ca++이온과 Mg++이온의 含量은 每年 增加하는 傾向을 나타내었다. A study was carried out to investigate the possibility of soil pollution in Onsan Industrial Complex. Physical and chemical properties of soil were analyzed. Soil samples were collected from paddy and upland soil around the Onsan Industrial Complex between 1988 and 1994. The results were summarized up as follows: Soil acidity of paddy and upland soil was slightly decreased every year respectively. Some sampling area and showed the strong acidity which was less than pH 5.0. For the characteristics of paddy soil, the content organic matter and phosphroic acid were lower than that of Korean average. The content of Mg ++ and Ca++ were increased by degree every year. In the case of upland, the content of organic matter and phosphoric acid showed similar pattern as low as Korean average. The content of K+ was higher as the value of 0.85me/100g comparing with the Korean average, 0.5me/100g. For the Mg++ and Ca++, the contents were also increased by degree every year, respectively.

RAPD법을 이용한 양파품종(Allium cepa L.)간의 유전변이와 유연관계분석

양보경,김도훈,이영병,남재성,정순재 동아대학교 농업생명과학연구소 2001 農業生命資援硏究 Vol.10 No.1

This study was carried out to investigate genetic variation and relationships among onion varieties, Allium cepa L., by RAPD-PCR analysis. In the test of 120 primers with 58 onion varieties collected from local and abroad, eight primers turned out to be useful for further analysis. These primers eventually provided a total of 71 bands, consisting of 68 polymorphic and three monomorphic ones. The polymorphic bands were subjected to phylogenetic analysis using NTSYS and PAUP computer programs. In the NTSYS analysis, similarity coefficient of the 58 onion varieties ranged from 0 to 0.9179 and that of 27 varieties with obvious origin ranged from 0.0306 to 0.9032, The dendrogram of 58 varieties obtained by NTSYS analysis resulted in 15 groups, but overall groupings were not consistent with bulb phenotypes (e.g., color, weight, and shape) or origin of the varieties either In the PAUP analysis, genetic divergence of the 58 onion varieties ranged from 0.042 to 0.532 and that of 27 varieties with obvious origin ranged from 0.042 to 0.394. Phylogenetic analysis using PAUP revealed 13 group with 58 varieties and nine group with 27 varieties, but these were not consistent with any bulb phenotypes or origin either, as seen in the NTSYS analysis.

참깨 種實의 發芽중 脂肪酸 組成의 變化에 관한 硏究

鄭大守,金度勳,丁海鎭,金賢勍 東亞大學校生命資源科學大學附設 農業資源硏究所 1995 農業生命資援硏究 Vol.4 No.1

참깨 種子를 25℃의 incubator에서 10日 동안 發芽시키면서, 發芽後 1日, 3日, 5日, 10日로 區分하여 試料를 採取하여 油脂含量과 脂肪酸組成의 變化를 比較 分析한 結果는 참깨 種子 發芽中 油脂含量의 變化는 發芽前 안산깨가 53.8%, 단백깨가 52.5% 發芽後 5日에 18.8%와 13.6%, 10日째에 9.3%와 7.3%로 減少하였다. 그리고 總脂質中의 脂肪酸 組成은 幼植物이 成長함에 따라 palmitic acid, stearic acid 및 linolenic acid는 增加하였으나, linoleic acid는 減少하는 傾向을 나타내었고, 發芽後 5日과 10日의 子葉部와 胚軸部의 脂肪酸 組成은 linolenic acid는 急激히 增加하였으나, palmitic acid, stearic acid 및 oleic acid 減少하는 傾向을 나타내었다. Sesame(Sesamum indicum L.) seeds were germinated at 25℃ for 10 days in order to investigate changes in the oil contents and fatty acid composition of total lipid. The sample for analysis was distinguished with 1st day, 3rd day, 5th day and 10th day after germination. In Ansan and Danbak varieties during the germination period, the oil contents were decreased continuously from 53.8%, 52.5% pre-germination 18.8%, 13.6% on the 5th day, and 9.3%, 7.3% on the 10th day after germination. In fatty acid composition of total lipids, palmitic acid, stearic and linolenic acid were increased, but linoleic acid showed the opposite tendency, according to the growth of seedling. In fatty acid composition of cotyledon and seedling axis, linolenic acid was increased rapidly, but palmitic acid, stearic acid and oleic acid decreasing trends showed during the germination periods.

정신분열병에 대한 리스페리돈의 효과 및 안정성

이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.

A Study on the Initial Irreversible Capacity of Lithium Intercalation Using Gradually Increasing State of Charge

Doh, Chil-Hoon,Jin, Bong-Soo,Park, Chul-Wan,Moon, Seong-In,Yun, Mun-Soo The Korean Institute of Electrical Engineers 2003 KIEE International Transactions on Electrophysics Vol.3C No.5

Initial irreversible capacity (IIC) can be defined by means of the initial intercalation Ah efficiency (IIE) and the initial irreversible specific capacity at the surface (IICs) with the linear-fit range of the intercalation so as to precisely express the irreversibility of an electrode-electrolyte system. Their relationship was IIC = Qc - Q$_{D}$ = (IIE$^{-1}$ - 1) Q$_{D}$ + IICs in the linear-fit range of IIE. Here, Qc and Qd signify charge and discharge capacity, respectively, based on a complete lithium ion battery cell. Charge indicates lithium insertion to carbon anode. Two terms of IIE and IICs depended on the types of active materials and compositions of the electrode and electrolyte but did not change with charging state. In an ideal electrode-electrolyte system, IIE and IICs would be 100%, 0 mAh/g for the electrode and mAh for the cell, respectively. These properties can be easily obtained by the Gradual Increasing of State of Charge (GISOC).OC).

Initial Electrochemical Insertion/Desertion of Lithium into Hard Carbon

Doh, Chil-Hoon,Moon, Seong-In,Yun, Mun-Soo,Jin, Chang-Soo,Jin, Bong-Soo,Eom, Seung-Wook Korean Carbon Society 2000 Carbon Letters Vol.1 No.1

The initial irreversible capacity (IIC) of a hard carbon during the charge/discharge reaction is strongly affected by both the initial irreversible capacity on the carbon surface $(IIC_S)$ and the initial irreversible lithium insertion into carbon $(IIC_B)$. The initial coulombic efficiency of the insertion and the desertion of lithium (IIE) can be used as a performance to classify $IIC_B$ of the carbon. The $IIC_B$ was proportional to the specific discharge capacity with a slope, $IIE^{-1}$ - 1. The IIE of hard carbon had four regions. $IIE_A$ for the region of 0~95 mAh/g of $Q_{D1}$ was 60.2%. $IIE_B$ and $IIE_C$ for the regions of 95~172 mAh/g and 172~308 mAh/g had 84.9% and 91.5%, respectively. $IIE_D$ was appeared above 308 mAh/g. But, the $IIE_D$ was reduced to 82.1% compared with $IIE_C$. These IIE might be corresponding to lithium desertion from carbon at the region of 0~172 mAh/g range, lithium desertion from the micropore of carbon at the region of 172~308 mAh/g range, and to the lithium stripping of the plated lithium for the region above 308 mAh/g, respectively.