제주도 지하수 질산염 농도의 시·공간적 변화 특성: 장기(1993-2015) 모니터링 자료의 평가

김호림(Ho-Rim Kim),오준섭(Junseop Oh),도현권(Hyun-Kwon Do),이경진(Kyung-Jin Lee),현익현(Ik-Hyun Hyun),오상실(Sang-Sil Oh),감상규(Sang-Kyu Kam),윤성택(Seong-Taek Yun) 대한자원환경지질학회 2018 자원환경지질 Vol.51 No.1

1993년부터 2015년까지 관측된 제주도 지하수 장기모니터링 관측정(N = 4,835)에서 수집된 지하수 수질자료(N = 21,568)를 기반으로 질산성질소의 시공간적 변동 특성을 평가하였다. 제주도 지하수의 질산성질소 농도의 중앙값은 2.5 mg/L로서 다른 국가나 대륙의 조사 결과에 비해 다소 높거나 유사한 것으로 나타났다. 또한 지하수 용도, 행정구역 및 고도 별로 유의한 차이를 보였다. 특히, 산간 지역에 비해 저지대 해안가에 위치한 농업 및 주거지역에서 농도가 높음을 확인하였다. Mann-Kendall 및 Sen’s slope 분석을 활용한 질산성질소 농도의 추세 분석 결과, 하류 저지 대에 비해 중산간지역에서의 질산성질소 농도 증가 경향이 뚜렷하였다. 제주도 내 토지 피복의 시계열 변화 특성과 결부 지어 보면, 중산간지역의 오염 증가 추세는 농업지역의 확장 등 인위적 활동 증가에 기인한 결과로 판단된다. 반면,기지정된 지하수자원특별관리구역에서는 전반적으로 질산성질소 농도의 감소 경향이 나타났는데, 이는 지하수 관리 측면에서 수질관리를 위한 적극적인 정책이 유효함을 시사한다. 본 연구에서는 제주도 지하수의 질산성질소 오염관리를 위한 적정 방안을 제안한다. The spatio-temporal variations of nitrate concentrations in groundwater of Jeju Island were evaluated by an analysis of time series groundwater quality data (N = 21,568) that were collected from regional groundwater monitoring (number of wells = 4,835) for up to 20 years between 1993 and 2015. The median concentration of NO 3 -N is 2.5 mg/L, which is slightly higher than those reported from regional surveys in other countries. Nitrate concentrations of groundwater in wells tend to significantly vary according to different water usage (of the well), administrative districts, and topographic elevations: nitrate level is higher in low-lying agricultural and residential areas than those in high mountainous areas. The Mann-Kendall trend test and Sen’s slope analysis show that nitrate concentration in mid-mountainous areas tends to increase, possibly due to the expansion of agricultural areas toward highland. On the other hand, nitrate concentrations in the Specially Designated Groundwater Quality Protection Zones show the temporally decreasing trend, which implies the efficiency of groundwater management actions in Jeju. Proper measures for sustainable groundwater quality management are suggested in this study.

만성두통환자에게 적용한 비약물적 치료가 통증행동에 미치는 영향

최도영,임사비나,차남현,김건식,이재동,김수영,이윤호,이두익 EAST-WEST MEDICAL RESEARCH INSTITUTE KYUNG HEE UNI 2005 東西醫學硏究所 論文集 Vol.2005 No.-

Objectives : This study is a random-controlled post-design for confirmation of headache degree, quality of life, and satisfaction to therapeutical effect on chronic headache adults after management of non-medicinal treatment (acupuncture therapy and stellate ganglion block therapy). Methods : 51 clinical experiment participants were gathered and through a questionnaire patients who experienced headache for more than 4 hours a day and more than 15 days per month were qualified as chronic headache patients. The qualified patients were classified in to two groups, acupuncture group (AT group, n=28) and stellate ganglion block group (SGB group, n=23). Treatment was applied 2 times a weeks for 4 weeks. The effects of both groups were analyzed using VAS scores, BPI (Brief Pain Inventory) and the satisfaction degree to the therapy. Results : 1. The recognized score of the headache of AT group and SGB group was reduced indicating the degree of the headache was released. 2. The recognition at damage to the quality of life was reduced post therapy of AT group and SGB group, in which general activity, mood, enjoyment of life, personal relationship, and sleeping showed significant improvement of life quality. 3. The satisfaction degree to the therapy showed lower score than expectation to it in AT group and SGB group, however, it was not significant. Conclusions : The results showed that the four-week non-medicinal treatment (AT and SGB) in chronic headache patients was effective for reducing headache and releasing its damage in daily life, however, no difference in superiority was found. Therefore, non-medicinal treatment (AT therapy and SGB) could be utilized in chronic headache patients.

식물에서 분리된 phenolic compound의 항암활성

이도익,조장현,이민원,홍순각 중앙대학교 약학연구소 1996 약학 논총 Vol.10 No.-

3,4'-dihydroxypropiophenone, a phenylpropanoid, purified from Betula platyphylla var. latifolia was evaluated on the antitumor activity. In vitro, the cytoxicity was determined by 0.4% trypan blue dye exclusion method. And the most sensitivity cell line was L5178Y(ED_50=0.96ug/ml). The ED_50 of 3, 4'-dihydroxypropiophenone against sarcoma-180, L-1210 were 8.77 and 2.69ug/ml respectively. As a result, 3, 4'-dihydroxypropiophenone was considered to show the antitumor activity.

무도 전공 학과별 취업인식 조사 : 용인대학교 무도대학 소속 학과를 중심으로

이병익,강성철,김도준,박준석,김주연 용인대학교 2011 용인대학교 논문집 Vol.29 No.-

The aim of this survey is employment perception of martial arts major students in yongin university. The university education has various objects, one of the most important purpose is opportunities for employment. As time have changed, martial arts major students pointed out that their needs for employment. If universities accept their needs, it can be raise competitiveness of martial arts major departments in the academic world. This research is released its earnings report, the data will have significant meanings for the martial arts major departments sector grappling with traditional understanding. Therefore a realistic employment measure is urgently needed for martial arts major students, because it will need to be tailored to fit into the realities and by the limitations of martial arts major's departments curriculum. The research found the martial arts major students's cognitions on employment planning of individualized department education, employment education management of martial arts major departments and martial arts education system from university to society through questionnaires. From this point of view, this research was based on students who belonging to the college of martial arts(judo, taekwondo, combative martial arts, oriental martial arts, security service) in yongin university.

터어키안 종양의 경접형골 수술례에 대한 임상분석

신동익,고영초,조맹기,황도윤 대한신경외과학회 1993 Journal of Korean neurosurgical society Vol.22 No.1

The most common severe cervical spine injury involving the posterior elements is subluxation or dislocation in which the posterior ligamentus complex is completely tom. Late instability is more common than previously realized, because ligamentous structures do not reconstitute normally. even with prolonged external rigid fixation. Subluxation of the cervical vertebrae in a flexion injury can be reduced by skeletal traction ; however, they usually require posterior stabilization. Unilateral and bilateral facet dislocation freqently require open reduction and posterior stabilization. The authors have used interlaminar clamps for the stabilization of thirty cases of unstable cervical spine. Advantages of this method are 1) immediate and rigid stabilization without cord injury. 2) early ambulation and prevention of respiratory complication and pressure sore. And also, posterior cervical stabilization with Halifax clamps is an easier, safer and faster technology in treatment of unstable spine.

Diarylheptanoid의 일종인 Oregonin의 항암효과

이도익,장재권,이민원,홍순각 중앙대학교 약학연구소 1988 약학 논총 Vol.12 No.-

Oregonin, a diarylheptanoid derivative from Alrus hirsuta Turcz, Betulaceae was evaluated on the antitumor activity. Oregonin, a diarylheptarioid zyloside is a novel immunomodulator augmenting macrophage and natural killer cell activity related anti-tumor functions. To investigate cytotoxicity of oregonin on tumor cells, the effect of the substance on three cell lines(P815, Yac-1, B16-F10) was examined. The result was somewhat different between suspension and adhesion cells. The growth-rate of suspension cells(P815, Yac-1) was not cut down significantly, but in contrast, the inhibitory activity on adhesion cell(B16-F10) was effective. Its ED50 is 20.09㎍/㎖(4.19×10^-5mol/l)

A Restricted Generalized Inverse and its Application to Constrained Minimization Problem

김도현,김익성 濟州大學校 師範大學 科學敎育硏究所 1988 科學敎育 Vol.5 No.-

Pedunculagin(Purified tannin)의 BRM Response

이도익,장재권,이민원,홍순각 중앙대학교 약학연구소 1998 약학 논총 Vol.12 No.-

Pedunculagin, an ellagitannin from Alrus hirsuta var. microphylla, Betulaceae was evaluated on the antitumor activity. To investigate cytotoxicity of pedunculagin on tumor cells, the effect of the substance on three cell lines(P815, Yac-1, B16-F20) was examined. And the result was somewhat different among three cell lines. The growth-rate of P815 was not cut down significantly, but in contrast, the inhibitory activities on Yac-1 and B16-F10 were effective. ED_50s of pedunculagin against P815, Yac-1 and B16-F10 were 12.16, 1.89, 3.30㎍/㎖ respectively.

퇴행성 슬관절염 환자의 증상 중증도 측정을 위한 적외선 체열상의 유용성

이두익,김건식,김수영,최도영,이상훈,이재동,이윤호 EAST-WEST MEDICAL RESEARCH INSTITUTE KYUNG HEE UNI 2005 東西醫學硏究所 論文集 Vol.2005 No.-

Objectives: To investigate the applicability of thermography as severity measurement in the patients with osteoarthritis (OA) of the knee. Methods: Data were obtained from 80 patiens with OA of the knee. They were asked to answer two disease-specific questionnaire (Western Ontario and McMaster Universities (WOMAC) OA index, Lequesne's Functional Index (LEI)), one generic instrument (Korean Health Assessment Questionnaire (KHAQ)), Visual Analogue Scale (VAS) pain intensities in order to assess the severity of disease, quality of life, and degree of pain and taken thermography in standardized environment before and after treatment, respectively. Results: The thermal differences between ipsilateral side and contralateral side in lateral aspect, medial aspect, patella region and suprapatella of both knees were correlated with pain lesion sites. Age, duration of disease, duration of morning stiffness, sex, and crepitus of knee were not correlated with the thermal differences of each regions. And also LFI, WOMAC, WOMAC pain subscale, WOMAC stiffness subscale, WOMAC physical function, KHAQ, were not correlated with the thermal differences of each region. But, the changes of VAS pain intensities were highly correlated with the thermal differences of each regions, especially in patelaa and suprapatella of knees after teratment. Conclusions: Although several specific evaluation indices for osteoarthritis of knee were not correlated with the degree of thermal differences between both knees, the differences of pain intensity (VAS) were quit correlated with thermal differences after treatment. And infrared thermography might be a very useful devices fot the evaluation of OA of knee and its treatment. Further study on the thermography on OA of the knee in more size of patients with appropriate severity grade and the standardization of analysis of thermographic data were recommended.

Risperidone으로 호전된 Capgras' Syndrome

지익성,배경도,이선우 충남대학교 의과대학 지역사회의학연구소 1996 충남의대잡지 Vol.23 No.2

A case of Capgras' syndrome in a 19-year-old girl who improved on Atypical antipsychotics, Risperideone is described. The patient's delusion of misidentification (She believed that her parents are not truly her parents and even she herself is not she) was treated with Risperidone. She showed significantly improvement. Authors believe Risperidone's antipsychotic effect in the treatment of schizophrenia warrants its consideration in alleviating other delusions of various psychotic disoreders, including the dedusion of doubles.