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도명식,배현숙 한밭대학교 2004 한밭대학교 논문집 Vol.21 No.-
Kalman filtering algorithm have been widely studied for estimation topics. Transportation application of Kalman filtering method includes, namely, travel demand estimation, travel time estimation etc. The aim of this study is to develop link travel time forecasting model by using Kalman filtering method. For estimation of travel time, traffic volume and mean velocity data from detectors are used. Also, In order to measure travel time by the time difference at each link or sectional data, license plate matching techniques are adopted. Target section is determined on a part of National road number 3, which is pilot section of NHTMS(National Highway Traffic Management System). It runs 10.72km from Gonjiam IC to Jang-ji IC. The observed and estimated travel time based on homogeneous section data are very close in cases of normal traffic flows.
明平根,成洛道,朴勝熙,鄭憲俊,吳仁敎 순천향대학교 1982 논문집 Vol.5 No.4
An investigation of the water quality for the streams of Daejon area in Chung-nam province, korea, was conducted from January to December 1981. By this analysis of water quality for the streams of Daejon area, annual mean values of BOD: 49.3㎎/l, COD: 33.4㎎/l, DO: 7.5㎎/l, SS: 39.1㎎/l were determined respectively and those values of parameters were comparatively high. The increasing order of the water pollution for the streams of Daejon area was as follows; confluence place Daewha-Dang (D)> Yudeung Stream (B)> Daejon Stream (A)> Gab Stream (C). Therefore, it suggest that the water pollution of the streams of Daejon area have greatly influenced upon the water quality of Kum River in Chungnam and Jon-buk province.
Irbesartan과 Lercanidipine의 병용요법이 고혈압 및 혈관재형성에 미치는 효과
이도형, 임태완, 조은지, 박현수, 정상혁, 한주희, 병창선 충남대학교 약학대학 의약품개발연구소 2017 藥學論文集 Vol.32 No.-
Hypertension is one of the major risk factor for cardiovascular disease and can lead to or make worse many complications, heart disease, atherosclerosis and diabetes. Thus, managing blood pressure effec tively using therapeutic drugs such as angiotensin II receptor blocker (ARB) and Ca2+ channel blocker (CCB) can be prevent other complications. Therefore, we investigated the synergistic effect of these two drugs, ir besartan and lercanidipine, for antihypertension, cardioprotection and antidiabetes. Irbesartan (28.74 mg/kg, 14.37 mg/kg) or lercanidipine (1.92 mg/kg, 0.96 mg/kg) alone or combination was administered to sponta-neously hypertensive rats (SHRs) and C57BL/6 mice. A two-week treatment of combination with irbesartan and lercanidipine significantly attenuated systolic blood pressure (SBP) and mean arterial pressure (MAP) compared with monotherapy. Futhermore. the combination therapy protected myocardial ischemia reperfusion injury more effectively than monotherapy. In vascular remodeling, combination therapy significantly diminished cuff -induced neointima formation and reduced serum -indllced vascular smooth muscle cells (VSMCs) pro-liferation compared with monotherapy. However, combination therapy had no significant synergistic effect of blood glucose regulation. Taken together, present study suggest that the combination therapy of irbesartan and lercanidipine may be more effective therapeutic strategy for the treatment of hypertension and related complications, myocardial infarction and arterial restenosis than monotherapy
도명식,한대석,유영근 한밭대학교 2004 한밭대학교 논문집 Vol.21 No.-
Travel time estimation has been recognized as one of the most critical elements of Intelligent Transportation Systems. This paper presents a method for estimating link travel time using neural network method. For estimation of travel time, traffic volume and mean velocity data from detectors are used. Also, In order to measure travel time by the time difference at each link or sectional data, license plate matching techniques are adopted. Target section is determined on a part of National road number 3, which is pilot section of NHTMS(National Highway Traffic Management System). It runs 10.72km from Gonjiam IC to Jang-ji IC. Neural network based travel time estimation model has been developed and tested using different data sets such as each link-based traffic data set and homogeneous section based data set. The optimal configuration of the neural network architecture is determined by self organization method. In conclusion, we know that the model by using all road section data is more efficient.
백도명,백남원,최정근,손미아,임정기,이원진,문영한,박정선,최병순 大韓産業醫學會 1995 대한직업환경의학회지 Vol.7 No.1
Asbestos industry has been in operation over 60 years in Korea. However, the prevalence of asbestosis has not been yet reported. With rapid turn-over of workers, previous cross-sectional studies of current workers on the job could not find cases with exposures long enough for the development of asbestosis. This study was done to evaluate asbestosis prevalence of those worksites with operation history of more than 20 years. In total, 139 workers from 5 worksites were examined. Asbestos industries covered in the study include 2 asbestos textile, 1 brake lining, and 2 ship repairing worksites. Chest x-ray was taken from all workers and read by two experts familiar with pneumoconiosis classification according to 1980 ILO guidelines. Those with findings compatible with asbestosis were further ckecked with high resolution computerized tomography (HRCT). Pulmonary function tests were done according to ATS guidelines, and occupational and previous medical history was taken through a standardized interview. Air-borne asbestos was measured according to NIOSH method 7400. The air-borne asbestos concentrations ranged from 0.2-1.3 f/cc for asbestos textile, from 0.7-1.0 f/cc for brake lining, and from 6.3-7.8 f/cc during asbestos removal at ship repairing worksite. Of the 139 workers 25 had abnormal chest radiographic findings, and 10 of them had findings compatible with pneumoconiosis. When work history and current asbestos measurements were accounted, 9 workers who had more than 10 years of asbestos exposure history showed chest radiographic findings of pneumoconiosis with Finally, 4 workers showed finding of pulmonary fibrosis and/or pleural thickening at HRCT, and 2 of them had restrictive lung function changes. The study results showed that, among 139 subjects, there were 4(3%) definite asbestosis cases confirmed with HRCT. The prevalence of probable asbestosis was 7% for 10-14 years of exposure, 13% for 15-19 years of exposure, and 23% for 20 or more years of exposure. The prevalence of compensable asbestosis with abnormal lung function was 4-6% for those with 15 or more years of exposure.
鄭泳都,朴世蔓,朴明均 明知大學校 産業技術硏究所 2003 産業技術硏究所論文集 Vol.22 No.-
Abstract - There are various methods to join mechanical structures together. They typically include welding, mechanical joints by bolts and other processes depending on specific needs. Analyses of joints in the mechanical structures are essential in understanding the dynamic characteristics of the structures. In this research an impulse technique is applies to investigate the dynamic behavior of joints produced by bolts. The length of overlap in the joints was varied as the number of the bolts in the joints was changed. Also, the torque applied to the bolts were adjusted. Resonance frequencies were determined for the joints to evaluate the relationship between the increase in the applied torque and the increase in the number of bolts used in the joints. The results have demonstrated that the resonance frequencies of the joints increase with the increasing torque.
유한요소법을 이용한 볼트결합 구조부의 조건에 따른 동적변화 해석
鄭泳都,朴世蔓,朴明均 明知大學校 産業技術硏究所 2003 産業技術硏究所論文集 Vol.22 No.-
To join structure together, various methods and processes are available including welding, riveting, bonding with industrial adhesives and fastening by bolts. Analysis of the common areas formed by joining between the structure are significant in that their results can provide critical information for understanding the dynamic behavior of the whole structure. The structural factors affecting the dynamic behavior of the joined structures are usually believed to be materials composing the bolts, bolt sizes and the number of bolts as well as the strength of applied torque and the extent of overlap between the structures joined together. This paper analyzes the impacts of the structural factors such as the bolt sizes, the extent of overlap and the materials composing the structures on the dynamic behavior of the joined structures.
자매에서 발생한 중증 마이코플라즈마 폐렴에서 스테로이드 치료
김도희,이경일,김명숙,윤유숙,황자영,임정우,강진한,이준성 대한감염학회 2009 감염과 화학요법 Vol.41 No.3
Numerous evidences support the pathogenesis that M. pneumonias pneumonia is associated with cell-mediat-ed immune reaction. We report 2 cases of severe M. pneumoniae pneumonia in previously healthy sisters, who were both admitted during an epidemic of M. pneumoniae pneumonia. The elder sister, who was 16 years old, was admitted with M. pneumoniae pneumonia. She showed no response to treatment with clarithroycin and levo-floxacin, and eventually progressed to severe ARDS, requiring mechanical ventilation. After treatment with hydrocortisone (200 mg/day), there were rapid improvements in clinical manifestations and chest radiographic findings. The younger sister, who was 14 years old, was admitted 10 days later, Presenting with fever but no pneumonic lesions on chest radiograph. Just like her sister, the infection showed no response to clarithromycin. Fever persisted and pneumonic consolidation with mild pleural effusion was noticed in the left lower lobe on the 5th hospital-day. After treatment with oral prednisolone (1 mg/kg), she showed rapid defervescence and on the 8th hospital day, no pneumonic lesions were detectable on chest radiograph. Given the fact that the pathogenesis of pneumonia and extrapulmonary manifestations in M. pneumoniae infection is immune-mediated, an immuno-suppressive therapy would be validated for selected patients with M. pneumoniae infections.