In vitro Antioxidant Activity of Ethanolic Extract of Chlorophytum borivilianum

R. Govindarajan1,,N. Sreevidya1,,M. Vijayakumar1,,M. Thakur2,,V.K. Dixit2,,S. Mehrotra*1,,P. Pushpangadan1 한국생약학회 2005 Natural Product Sciences Vol.11 No.3

Chlorophytum borivilianum Baker (Antharicaceae) comonly referred as ‘Safed Musli’ has beenwidely used in the Indian traditional systems of medicine to treat various diseases like rheumatism apart fromaphordisiac properties. C. borivilianum was screened for the first time to determine its antioxidant activity,isolation of the sapogenins and standardization of the isolated sapogenin fraction using HPTLC. Potent antioxidantactivity of ethanolic extract was found by their ability to scavenge DPPH (84.51%), hydroxyl radical (48.95 %),feryl bi-pyridyl complex (84.53%) along with the inhibition of lipid peroxidation (67.17%) at 100g/mlconcentration. The ethanolic extract also exhibited significant inhibition of superoxide anion radical generated byplant in the traditional system especially its use as a Rasayana drug.

DCT and DWT Based Methods for Detecting Copy-Move Image Forgery: A Review

Anuja Dixit,Rahul Dixit,R. K. Gupta 보안공학연구지원센터 2016 International Journal of Signal Processing, Image Vol.9 No.10

Nowadays, as various image manipulation tools are available very easily. Any person having a little knowledge about these tools can doctor the available images. So digital images are no longer trusted. Computer graphics and digital photography have made the tampering over image easy to commit but hard to detect. Although various image forgery techniques are available but copy-move image forgery is one of the most hard to detect image forgery. In Copy-Move image forgery a segment from the original image is copied and after performing some manipulation over that, segment is pasted at some other location on the same image. This forgery is intended to hide noticeable information shown by the image or for adding information in original image to convey a wrong message. We cannot identify such forgery on the basis of incompatibilities present in an image because the copied segment is taken from the same image so the properties like noise, blur, texture, color palette remain similar to the original image. So, copy-move image forgery is a serious threat to Image forensic Investigators. Researchers have developed several methods for detecting such kind of forgery based on exhaustive search and block based methods. Block based method is more successful in detecting such kind of forgery due to its speed and less complexity. In this paper we discuss forgery detection techniques based on Discrete Cosine Transform and Discrete Wavelet Transform.

Some Properties of Harmonic Functions Defined by Convolution

Dixit, Kaushal Kishor,Porwal, Saurabh Department of Mathematics 2009 Kyungpook mathematical journal Vol.49 No.4

In this paper, we introduce and study a comprehensive family of harmonic univalent functions which contains various well-known classes of harmonic univalent functions as well as many new ones. Also, we improve some results obtained by Frasin [3] and obtain coefficient bounds, distortion bounds and extreme points, convolution conditions and convex combination are also determined for functions in this family. It is worth mentioning that many of our results are either extensions or new approaches to those corresponding previously known results.

Growth and Characterization of Pulse Electrodeposited CuInSe2 Thin Films

Dixit Prasher,Poolla Rajaram 대한금속·재료학회 2012 ELECTRONIC MATERIALS LETTERS Vol.8 No.5

CuInSe2 thin films were grown on SnO2-coated glass substrates using the pulse electrodeposition (PED) technique. The CuInSe2 films were grown at different potentials using pulses of different frequencies ranging from 1 KHz to 1 MHz. The electrodeposited films were annealed in vacuum at 300°C, for 1 hr, to improve the crystallinity. The annealed films were characterized by x-ray diffraction (XRD), Scanning Electron Microscopy (SEM), Energy Dispersive Analysis of x-rays (EDAX), and UV-VIS-NIR spectra. The results show that the electrodeposited CuInSe2 films have good stoichiometry and are single phase with an optical gap around 1 eV. SEM studies show that the films grown using pulses of frequency 1 KHz contain nanoparticles of size 50-60 nm, whereas those grown using pulses of frequency 100 KHz and 1 MHz contain micronsized particles.

Efficient Estimation of the Parameters of the Pareto Distribution in the Presence of Outliers

Dixit, U.J.,Jabbari Nooghabi, M. The Korean Statistical Society 2011 Communications for statistical applications and me Vol.18 No.6

The moment(MM) and least squares(LS) estimations of the parameters are derived for the Pareto distribution in the presence of outliers. Further, we have derived a mixture method(MIX) of estimations with MM and LS that shows that the MIX is more efficient. In the final section we have given an example of actual data from a medical insurance company.

*-U-REGULAR RING

Dixit, V.N. Department of Mathematics 1977 Kyungpook mathematical journal Vol.17 No.1

Fast Disintegrating Films Containing Anastrozole as a Dosage Form for Dysphagia Patients

Dixit Anil Satyanarayana,Kulkarni Parthasarathi Keshavarao 대한약학회 2012 Archives of Pharmacal Research Vol.35 No.12

The objective of the present research was to ensure safety during oral administration of medications to dysphagia patients, by preparing fast disintegrating films (FDF) containing anastrozole (ANS) which disintegrate rapidly when placed on the tongue. Films were prepared by solvent-casting method using various polymers such as hydroxyl propyl methyl cellulose (HPMC E5 LV), hydroxy propyl cellulose (HPC), poly vinyl alcohol (PVA) and sodium alginate (Na Alginate). Among the formulations examined, film prepared using HPMC E5 LV (F1) exhibited shorter disintegration time (15 sec) with satisfactory mechanical properties. Fourier transformer infrared (FTIR) & differential scanning calorimetry (DSC) analysis revealed no chemical incompatibility between drug and excipients used in the formulation. Surface morphology revealed even distribution of ANS in the film. Dissolution of drug from F1 formulation was rapid with more than 90% drug release in 240 sec. Pharmacokinetic parameters showed no statistical difference between F1 (test) and drug solution (control) indicating comparable plasma level-time profiles. The film showed an excellent stability for 24 weeks when stored at refrigerated temperature (2-8oC). These findings suggest that the fast disintegrating film as a promising candidate for delivery of ANS in dysphagic patients.

Solvent Free N-Heterocyclization of Primary Amines to N-Substituted Azacyclopentanes Using Hydrotalcite as Solid Base Catalyst

Dixit, Manish,Mishra, Manish,Joshi, P.A.,Shah, D.O. Korean Chemical Society 2012 Bulletin of the Korean Chemical Society Vol.33 No.5

An ecofriendly catalytic route for selective synthesis of $N$-substituted azacyclopentanes, nitrogen-containing heterocyclic intermediates for many bioactive compounds, was established by carrying out $N$-heterocyclization (di $N$-alkylation) of primary amines with 1,4-dichloro butane (as dialkylating agent) using catalytic amount of hydrotalcite as solid base catalyst. The hydrotalcite was found to be efficient solid base catalyst for di $N$-alkylation of different primary amines (aniline, benzyl amine, cyclohexyl amine and n-butyl amine) giving 82 to 96% conversion (at optimized reaction condition) of 1,4-dichloro butane and > 99% selectivity of respective $N$-substituted azacyclopentanes within 30 min. under solvent free condition. The reaction parameters significantly influence the conversion of 1,4-dichloro butane to $N$-substituted azacyclopentanes. The nature of substituent present on amino group affects the reactivity of amine substrates for di $N$-alkylation reaction with 1,4-dichloro butane. The 1,4-dichloro butane was found to be highly reactive alkylating agent for di $N$-alkylation of amines as compared to 1,4-dihydroxy butane. The reusability of the catalyst and its chemical stability in the reaction was demonstrated.

Application of rifampicin as a chiral selector for enantioresolution of basic drugs using capillary electrophoresis

Dixit, S.,Park, J.H. Elsevier 2016 Journal of chromatography Vol.1453 No.-

<P>Rifampicin, a member of rifamycin sub-class of antibiotics which belongs to the naphthalenic ansamycin class of antibiotics, has a characteristic ansa structure, i.e., a ring structure or chromophore spanned by an aliphatic chain. The present work was designed to evaluate its potential as a chiral selector (CS) as its structure consisting of nine stereogenic centers, an aromatic moiety and several functional groups (i.e., one imine, one amide, one acetoxy residue, two aliphatic hydroxyl and three phenolic hydroxyl groups) was expected to instigate multiple enantioselective interactions, namely, hydrogen bonding and inclusion complexation with chiral analytes, and therefore resulting in efficient enantioseparations. Systematic experiments were performed to investigate the effects of concentration of CS, composition of background electrolyte (BGE) and applied voltage on chiral separation. Enantiomers of propranolol and metoprolol were baseline resolved using a BGE consisting of 20 mM CS and 50/50 (v/v) iso-propanol/phosphate buffer (100 mM, pH TO) whereas for enantiomers of sertraline, a BGE consisting of 23 mM CS and 40/60 (v/v) iso-propanol/phosphate buffer (100 mM, pH 7.0) resulted in baseline resolutions. (C) 2016 Elsevier B.V. All rights reserved.</P>

Genetic Structure and Differentiation of Three Indian Goat Breeds

Dixit, S.P.,Verma, N.K.,Aggarwal, R.A.K.,Kumar, Sandeep,Chander, Ramesh,Vyas, M.K.,Singh, K.P. Asian Australasian Association of Animal Productio 2009 Animal Bioscience Vol.22 No.9

Gene flow, genetic structure and differentiation of Kutchi, Mehsana and Sirohi breeds of goat from North-Western India were evaluated based on 25 microsatellite markers so as to support breed conservation and improvement decisions. The microsatellite genotyping was carried out using an automated DNA sequencer. The gene diversity across the studied loci for the Kutchi breed varied from 0.57 (ILST 065) to 0.93 (OarFCB 304, OMHC 1, ILSTS 058) with an overall mean of 0.79${\pm}$0.02. The corresponding values for Mehsana and Sirohi breeds were 0.16 (ILST 008) to 0.93 (OMHC 1, ILSTS 058) with an average of 0.76${\pm}$0.04, and 0.50 (ILSTS 029) to 0.94 (ILSTS 058) with an average of 0.78${\pm}$0.02, respectively. The Mehsana breed had lowest gene diversity among the 3 breeds studied. All the populations showed an overall significant heterozygote deficit ($F_{is}$). The Fis values were 0.26, 0.14 and 0.36 for Kutchi, Mehsana and Sirohi goat breeds, respectively. Kutchi and Mehsana were more differentiated (16%) followed by Mehsana and Sirohi (13%).The measures of standard genetic distance between pairs of breeds indicated that the lowest genetic distance was between Kutchi and Sirohi breeds (0.73) and the largest genetic distance was between Mehsana and Kutchi (1.0) followed by Sirohi and Mehsana (0.75) breeds. Mehsana and Kutchi are distinct breeds and this was revealed by the estimated genetic distance between them. All measures of genetic variation revealed substantial genetic variation in each of the populations studied, thereby showing good scope for their further improvement.