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Bharatkumar, Dave Heema,Singh, Dheerendra,Bansal, Hari Om The Korean Institute of Power Electronics 2019 JOURNAL OF POWER ELECTRONICS Vol.19 No.6
This paper proposes two modified Z-source inverter topologies, namely an embedded L-Z-source inverter (EL-ZSI) and a coupled inductor L-Z source inverter (CL-ZSI). The proposed topologies offer a high voltage gain with a reduced passive component count and reduction in source current ripple when compared to conventional ZSI topologies. Additionally, they prevent overshoot in the dc-link voltage by suppressing heavy inrush currents. This feature reduces the transition time to reach the peak value of the dc-link voltage, and reduces the risk of component failure and overrating due to the inrush current. EL-ZSI and CL-ZSI possess all of the inherent advantages of the conventional L-ZSI topology while eliminating its drawbacks. To verify the effectiveness of the proposed topologies, MATLAB/Simulink models and scaled down laboratory prototypes were constructed. Experiments were performed at a low shoot through duty ratio of 0.1 and a modulation index as high as 0.9 to obtain a peak dc-link voltage of 53 V. This paper demonstrates the superiority of the proposed topologies over conventional ZSI topologies through a detailed comparative analysis. Moreover, experimental results verify that the proposed topologies would be advantageous for renewable energy source applications since they provide voltage gain enhancement, inrush current, dc-link voltage overshoot suppression and a reduction of the peak to peak source current ripple.
Dave Heema Bharatkumar,Dheerendra Singh,Hari Om Bansal 전력전자학회 2019 JOURNAL OF POWER ELECTRONICS Vol.19 No.6
This paper proposes two modified Z-source inverter topologies, namely an embedded L-Z-source inverter (EL-ZSI) and a coupled inductor L-Z source inverter (CL-ZSI). The proposed topologies offer a high voltage gain with a reduced passive component count and reduction in source current ripple when compared to conventional ZSI topologies. Additionally, they prevent overshoot in the dc-link voltage by suppressing heavy inrush currents. This feature reduces the transition time to reach the peak value of the dc-link voltage, and reduces the risk of component failure and overrating due to the inrush current. EL-ZSI and CL-ZSI possess all of the inherent advantages of the conventional L-ZSI topology while eliminating its drawbacks. To verify the effectiveness of the proposed topologies, MATLAB/Simulink models and scaled down laboratory prototypes were constructed. Experiments were performed at a low shoot through duty ratio of 0.1 and a modulation index as high as 0.9 to obtain a peak dc-link voltage of 53 V. This paper demonstrates the superiority of the proposed topologies over conventional ZSI topologies through a detailed comparative analysis. Moreover, experimental results verify that the proposed topologies would be advantageous for renewable energy source applications since they provide voltage gain enhancement, inrush current, dc-link voltage overshoot suppression and a reduction of the peak to peak source current ripple.
Strategies towards Orthopaedic Tissue Engineered Graft Generation: Current Scenario and Application
SaradaPrasanna Mallick,Zerihun Beyene,Dheerendra Kumar Suman,Abhimanyu Madhual,Bhisham Narayan Singh,Pradeep Srivastava 한국생물공학회 2019 Biotechnology and Bioprocess Engineering Vol.24 No.6
Even though degradation and damage to bone and cartilage tissue can be resolved naturally, but there is a great challenge to regenerate functional tissue due to multiple pathological conditions. To treat the diseased/ damaged bone and cartilage tissue as well as to improve or maintain its natural functions and structure, there are different strategies being developed for repair and regeneration of these tissues. Various innovative researches lead to remarkable improvement in clinical outcome of defective bone and cartilage treatments. Biomaterial based scaffolds which are capable of supporting cell growth and applied for replacement of tissue in vivo for both bone and cartilage. The review also delineates about the tissue engineering bioreactors for the recreation of frameworks to recellularise the graft in vitro by presenting them to physiologically significant mechanical or potentially hydrodynamic stimulation condition. This review summarizes and discusses the strategies for regeneration and repair of bone and cartilage tissue, current scenario and application.
A new connecting technique in partial replantation of a ruptured peritoneal dialysis catheter
( Yae Ni Kim ),( Prashant C. Dheerendra ),( Yong-soo Kim ) 대한신장학회 2014 Kidney Research and Clinical Practice Vol.33 No.3
Peritoneal dialysis catheter ruptures have been managed by immediate removal andsubsequent reinsertion of the catheter which inevitably entails interruption inperitoneal dialysis and a need for vascular access. A 36-year-old man on continuousambulatory peritoneal dialysis complaining of dialysate leakage was found to have asmall rupture near the outer cuff of the peritoneal dialysis catheter. Rather thanemploying the traditional method of exchanging the whole catheter, a partialreplantation procedure to salvage the still-functioning conduit was performed. Twoperitoneal dialysis adaptors were used to connect the end of the remaining oldcatheter to a new extraperitoneal segment of a new catheter and a piece of atransfer set to connect the adaptors. A novel, yet simple and safe, means of partialperitoneal dialysis catheter replantation when managing catheter injuries issuggested.
Aditya Anand,Sarada Prasanna Mallick,Bhisham Narayan Singh,Shikha Kumari,Dheerendra Kumar Suman,Satyavrat Tripathi,Divakar Singh,Pradeep Srivastava 한국생물공학회 2022 Biotechnology and Bioprocess Engineering Vol.27 No.4
Usage of bioreactors in the field of tissue engineering has played a significant role in enabling a controlled and reproducible change in the formation of damaged tissue on being provided with specific factors. Owing to the scarcity seen in providing sufficient donor organs for transplantation there is a huge requirement for large-scale production of artificial organs. This cannot be achieved by static culturing since it does not provide an invivo three-dimensional (3D) microenvironment therefore tissue engineering plays a vital role in the development of artificial tissues and organs as per the clinical demands whereas bioreactors have served a major role in providing the artificial microenvironment required by the cells to grow further into a tissue and then into an organ. By providing the specific biochemical cues and mechanoresponsive stimuli the bioreactors turn to be very effective in generating transplantable organs. Apart from performing studies in a controlled manner aimed at understanding biological and physicochemical effects, bioreactors also ensure the safe and reproducible production of tissueengineered constructs to achieve cost-effective large-scale production. The design criteria for bioreactors to be used in tissue engineering include optimal aspect ratio, proper aeration for the cells to proliferate, and agitation with reduced shear stress. The current review summarizes important aspects like Height/Diameter ratio or aspect ratio, shear stress, mechanical stress, aeration, agitation, oxygenation, etc. related to the design of tissue bioreactors, different types of bioreactors that are in use to date, and the reported pieces of literature to yield an overview on the existing concepts. It mainly focuses on the generation of 3D tissue constructs in various reactor systems specially designed for their culture and development along with their applications.