Ride comfort of the bridge-traffic-wind coupled system considering bridge surface deterioration

Liu, Yang,Yin, Xinfeng,Deng, Lu,Cai, C.S. Techno-Press 2016 Wind and Structures, An International Journal (WAS Vol.23 No.1

In the present study, a new methodology is presented to study the ride comfort and bridge responses of a long-span bridge-traffic-wind coupled vibration system considering stochastic characteristics of traffic flow and bridge surface progressive deterioration. A three-dimensional vehicle model with 24 degrees-of-freedoms (DOFs) including a three-dimensional non-linear suspension seat model and the longitudinal vibration of the vehicle is firstly presented to study the ride comfort. An improved cellular automaton (CA) model considering the influence of the next-nearest neighbor vehicles and a progressive deterioration model for bridge surface roughness are firstly introduced. Based on the equivalent dynamic vehicle model approach, the bridge-traffic-wind coupled equations are established by combining the equations of motion of both the bridge and vehicles in traffic using the displacement relationship and interaction force relationship at the patch contact. The numerical simulations show that the proposed method can simulate rationally the ride comfort and bridge responses of the bridge-traffic-wind coupled system; and the vertical, lateral, and longitudinal vibrations of the driver seat model can affect significantly the driver's comfort, as expected.

Insulin receptors regulate the fecundity of Nilaparvata lugens (Stål) (Hemiptera: Delphacidae)

Liu Yong-Kang,Luo Yu-Jia,Deng Ying-Mei,Li Yan,Pang Xiao-Qing,Xu Cai-Di,Wang Shi-Gui,Tang Bin 한국응용곤충학회 2020 Journal of Asia-Pacific Entomology Vol.23 No.4

Two InR (insulin receptor) genes have been identified in the Nilaparvata lugens. In this study, we used RNA interference (RNAi) to investigate the role of InR genes in the fecundity of N. lugens. The expression of NLInR1 and NLInR2 genes was simultaneously silenced with mixture of dsInR1 and dsInR2 (dsInRs) injection. Our results showed that larvae RNAi against both NLInR1 and NLInR2 reduced the number of eggs laid by N. lugens and some eggs as well as ovaries were abnormal. In addition, the relative expression of Vg (vitellogenin) and VgR (vitellogenin receptor) was significantly reduced on the 4th and 6th days after insects treated with larvae RNAi reached the adult stage. We also determined the relative expression levels of insulin/insulin-like signaling (IIS) related genes in RNAi-treated larvae and found that the expression levels of Chico (homologous receptor substrate), Akt (protein kinase B), PI3K (phosphoinositide 3-kinase), and PTEN (phosphatase and tensin homolog) genes decreased whereas FOXO (forkhead box O) and GSK3 (glycogen synthase kinase-3) levels increased on the 4th and 6th days after insects reached the adult stage. These results indicate that silencing of NLInR1 and NLInR2 reduces the fecundity of N. lugens through the IIS pathway.

Fabrication of porous polymer microparticles with tunable pore size and density through the combination of phase separation and emulsion-solvent evaporation approach

Liu, Shanqin,Cai, Mingle,Deng, Renhua,Wang, Jianying,Liang, Ruijing,Zhu, Jintao 한국유변학회 2014 Korea-Australia rheology journal Vol.26 No.1

A facile and versatile route to prepare porous polymer microparticles with tunable pore size and density through the combination of phase separation and emulsion-solvent evaporation method is demonstrated. When volatile organic solvent (e.g., chloroform) diffuses through the aqueous phase containing poly(vinyl alcohol) (PVA) and evaporates, n-hexadecane (HD) and polystyrene (PS) in oil-in-water emulsion droplets occur to phase separate due to the incompatibility between PS and HD, ultimately yielding microparticles with porous structures. Interestingly, density of the pores (pore number) on the shell of microparticles can be tailored from one to hundreds by simply varying the HD concentration and/or the rate of solvent evaporation. Moreover, this versatile approach for preparing porous microparticles with tunable pore size and density can be applied to other types of hydrophobic polymers, organic solvents, and alkanes, which will find potential applications in the fields of pharmaceutical, catalyst carrier, separation, and diagnostics.

Influence ofMgOoverlayers on the electronic states of bctCo(001)thin films grown on bccFe(001)∕GaAs(001)

Tong, Liu-Niu,Deng, Cai-Lian,Matthes, Frank,Mü,ller, Martina,Schneider, Claus M.,Lee, Chan-Gyu American Physical Society 2006 Physical review. B, Condensed matter and materials Vol.73 No.21

Inflammatory Endotypes and Tissue Remodeling Features in Antrochoanal Polyps

Chen Cai-Ling,Wang Yu-Ting,Yao Yin,Pan Li,Guo Bei,Zhu Ke-Zhang,Ma Jin,Wang Nan,Li Xue-Li,Deng Yi-Ke,Liu Zheng 대한천식알레르기학회 2021 Allergy, Asthma & Immunology Research Vol.13 No.6

Purpose: The pathogenic mechanisms of antrochoanal polyps (ACPs) remain largely unknown. This study aimed to characterize inflammatory patterns and tissue remodeling features in ACPs. Methods: Inflammatory cell infiltration and tissue edema severity as well as fibrin deposition in ACPs and bilateral eosinophilic and noneosinophilic nasal polyps (NPs) were studied with immunohistochemical and immunofluorescence staining. Cytokine levels in sinonasal tissues were detected with the Bio-Plex assay. The expression of coagulation and fibrinolytic markers was measured using reverse-transcription polymerase chain reaction and enzyme-linked immunosorbent assays. Results: Compared to control tissues and bilateral eosinophilic and noneosinophilic NPs, ACPs had higher levels of neutrophil infiltration and expression of myeloperoxidase (MPO), interleukin (IL)-8 and interferon (IFN)-γ. In total, 94.4% of ACPs demonstrated an eosinophil cationic protein/MPO ratio of < 1, compared to 79.0% of noneosinophilic and 26% of eosinophilic NPs. Principle component and multiple correspondence analyses revealed a neutrophilic and type 1 inflammation pattern in ACPs. Compared to control tissues, edema scores and fibrin deposition were increased, whereas d-dimer and tissue plasminogen activator (tPA) levels were decreased in ACPs and bilateral NPs, with more prominent changes in ACPs even than in eosinophilic NPs. The tPA levels were negatively correlated with IFN-γ, IL-8, and MPO levels in ACPs. Neutrophils were the major cellular source of IFN-γ in ACPs, and the number of IFN-γ+ neutrophils was elevated in ACPs than in control tissues and bilateral eosinophilic and noneosinophilic NPs. Conclusions: ACPs are characterized by the neutrophilic and type 1 inflammation endotype. Neutrophil-derived IFN-γ is associated with reduced tPA production in ACPs.

Ride comfort of the bridge-traffic-wind coupled system considering bridge surface deterioration

Yang Liu,Xinfeng Yin,Lu Deng,C. S. Cai 한국풍공학회 2016 Wind and Structures, An International Journal (WAS Vol.23 No.1

In the present study, a new methodology is presented to study the ride comfort and bridge responses of a long-span bridge-traffic-wind coupled vibration system considering stochastic characteristics of traffic flow and bridge surface progressive deterioration. A three-dimensional vehicle model with 24 degrees-of-freedoms (DOFs) including a three-dimensional non-linear suspension seat model and the longitudinal vibration of the vehicle is firstly presented to study the ride comfort. An improved cellular automaton (CA) model considering the influence of the next-nearest neighbor vehicles and a progressive deterioration model for bridge surface roughness are firstly introduced. Based on the equivalent dynamic vehicle model approach, the bridge-traffic-wind coupled equations are established by combining the equations of motion of both the bridge and vehicles in traffic using the displacement relationship and interaction force relationship at the patch contact. The numerical simulations show that the proposed method can simulate rationally the ride comfort and bridge responses of the bridge-traffic-wind coupled system; and the vertical, lateral, and longitudinal vibrations of the driver seat model can affect significantly the driver`s comfort, as expected.

Comparison of drought resistance of rootstocks 'M9-T337' and 'M26' grafted with 'Huashuo' apple

Shi Cai-Yun,Liu Li,Li Qiu-Li,Wei Zhi-Feng,Gao Deng-Tao 한국원예학회 2022 Horticulture, Environment, and Biotechnology Vol.63 No.3

Drought stress is one of the main limiting factors in apple (Malus domestica Borkh.) cultivation. Rootstock plays an important role in the drought tolerance of apple plants. ‘M.9-T337’ is a novel apple rootstock that was recently introduced and widely cultivated in China. In this study, we selected the new, widely promoted Chinese apple variety ‘Huashuo’ as the scion and grafted it onto ‘M.9-T337’ (HM9). Another combination, ‘Huashuo’/‘M.26’/Malus robusta Rehd. (HM26), served as the experimental control to analyse drought resistance in the two hybrids. We believe that this empirical approach is more representative than merely studying rootstock seedlings. After sustained drought stress for over 1 month, the leaf relative water content had decreased in both types of plants, but to a lesser extent in HM26 than in HM9. The SPAD values increased in both plants, but without significant difference. Drought stress reduced photosynthetic activity in both plants, and the net photosynthetic rate was higher in HM26 than in HM9. The observed changes in the chlorophyll fluorescence parameters indicated that drought had damaged the PSII activity centres of both plants, photosynthetic electron transfer was inhibited, and excessive excitation energy accumulated. However, compared to HM26, HM9 displayed lower maximal PSII quantum photochemical efficiency and potential PSII activity. Moreover, HM9 showed lower antioxidant enzyme activity than HM26 under drought stress. A membership function analysis confirmed that ‘M.9-T337’ was less drought resistant than ‘M.26’. Nevertheless, ‘M.9-T337’ could still recover after prolonged drought stress, indicating it also had good drought resistance.

Optimization of Processing Conditions of Chinese Smoke-cured Bacon (Larou) with a New Natural Coating Solution during Storage Period

Na Liu,Qiujin Zhu,Xuefeng Zeng,Bowen Yang,Meilian Liang,Li Deng,Laping He,Cai Liang,Ruping Zhang,Juan Zhou 한국축산식품학회 2018 한국축산식품학회지 Vol.38 No.3

The study aims to determine the optimum sterilization rate and water activity of Chinese traditional smoke-cured bacon product (Larou) in the preservation with natural coating solution. With the response surface methodology (RSM), we analyzed 3 factors of processing conditions (the concentration of lysozyme, concentration of sodium alginate, and concentration of chitosan) and 2 response factors (sterilization rate and water activity). Sterilization rate and water activity of Larou were largely affected by the concentration of lysozyme, concentration of sodium alginate, and concentration of chitosan. The final optimum concentrations of lysozyme, sodium alginate, and chitosan were 0.09, 1.40, and 1.60% and realized the high sterilization rate. Water activity of sliced Larou was significantly correlated with the sterilization rate. Low-field nuclear magnetic resonance analysis verified the optimum processing conditions. The coating resulted in 99.69% rate of reducing bacteria after 30-day storage. The data of the total number of colony, peroxidation value, moisture content, pH, and sensory evaluation provided the theoretical basis for extending the shelf life of Chinese traditional smoke-cured bacon product (Larou) with natural coating solution.

Comparative Evaluation of Hepatoprotective Activities of Geniposide, Crocins and Crocetin by CCl₄-Induced liver Injury in Mice

Chen, Ping,Chen, Yang,Wang, Yarong,Cai, Shining,Deng, Liang,Liu, Jia,Zhang, Hao The Korean Society of Applied Pharmacology 2016 Biomolecules & Therapeutics(구 응용약물학회지) Vol.24 No.2

Iridoid glycosides (mainly geniposide) and crocetin derivatives (crocins) are the two major active constituents in Gardenia jasminoides Ellis. In the present study, geniposide, crocins, crocin-1 and crocetin were separated from gardenia chromatographically. Then, mice were orally administrated with geniposide (400 mg/kg b.w.), crocins (400 mg/kg b.w.), crocin-1 (400 mg/kg b.w.) and crocetin (140 mg/kg b.w.) once daily for 7 days with $CCl_4$. Hepatoprotective properties were evaluated by biochemical parameters: Administration of geniposide, crocins, crocin-1and crocetin significantly lowered serum alanine transaminase (ALT), aspartate transaminase (AST) and alkaline phosphatase (ALP) levels in $CCl_4$-treated mice. The reduced glutathione (GSH) levels and antioxidant enzymes (SOD and CAT) activities were also increased by geniposide, crocins, crocin-1 and crocetin. Histopathological examination of livers showed that these components reduced deformability, irregular arrangement and rupture of hepatocyte in $CCl_4$-treated mice. These biochemical results and liver histopathological assessment demonstrated that geniposide, crocetin derivatives and crocetin show comparative beneficial effects on $CCl_4$-induced liver damage via induction of antioxidant defense. Therefore, contents of geniposide and crocetin derivatives should be both considered for hepatoprotective efficacy of Gardenia jasminoides Ellis.

Citrus Genetic Transformation with Interest Target Genes for Cultivar Improvement

Wenwu Guo,Yanxin Duan,Dingli Li,Xin Liu,Bin Tan,Xiaodong Cai,Xiuxin Deng 한국원예학회 2006 한국원예학회 기타간행물 Vol.- No.-