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추호정;Pysarchik, Dawn Thorndike 한양대학교 2004 韓國 生活 科學 硏究 Vol.- No.23
In the current globalizing marketplace, consumers encounter various products with multiple country-of-origins everyday. New terms in international trade such as “captive import”, “transplant” and “hybrid” represent complicated country of origin cues many global products are carrying. To predict consumer behavior in these markets, therefore, it is necessary to understand how consumers use country of origin cues in their purchase decision making processes. Consumer ethnocentrism has been known as one of individual characteristics which determine the effect of country of origin. The primary purpose of this study is the Korean consumers‘ ethnocentric tendency. Specifically, the study compares ethnocentric tendency of Korean consumers in the year of 1995, 1997, and 2000. Also this study examines the relationships between ethnocentrism and demographic factors including age, gender, marital status, and monthly income, product attribute evaluation, quality perception, and purchase intention. The empirical part of the study is conducted with survey data collected from Korean students of a major mid-western university in the US and their family in the year of 1995, 1997, and 2000.The result shows that Korean consumers have stronger ethnocentric tendency in 1997 than in 1995 and 2000, which implies that economic crisis in Korea might stimulate consumers to become more economically conservative. The study confirms previous studies arguing consumers’ demographic factors and ethnocentrism are closely related. Women, married, older, and middle income consumers are likely to have stronger ethnocentric tendencies in Korea. Consumers’ attribute evaluation (design, comfort, and brand image), quality perception, and purchase intention for domestic brand jeans (Nix)and an imported brand jean (Levi) are compared. Consumer ethnocentrism seems to affect purchase intention but not attribute evaluations and quality perception. Consumer Ethnocentrism, Economic Crisis, Demographics, Product Attribute Evaluation, Quality Perception, Purchase Intention
( Dawn Chung ),( Kiyoon Eom ),( Sunyoung Park ),( Hyemi Cho ),( Kwang Hwa Park ),( Hyeyoung Lee ) 대한산부인과학회 2016 대한산부인과학회 학술대회 Vol.102 No.-
목적: MicroRNAs (miRNAs) are small noncoding RNAs of about 22 nucleotides and have negative regulatory action of gene expression at post-transcriptional period through mRNA degradation and/or translation repression. These molecules have been studied as potential biomarkers in many important biological processes, including cell growth, apoptosis, viral infection and cancer development. Several oncogenic miRNAs have been reported to be associated with cervical cancer tumorigenesis as well. 방법: Among many oncogenic miRNAs, miR-9, miR-21, miR-155, and miR-944 are known to promote cell growth, migration and invasion in cervical cancer. However, the relationship between miRNAs and HR-HPV infection has not been fully understood, and few studies have been generated using clinical samples. The aim of this study was to investigate the expression levels of miR-9, miR-21, miR-155, and miR-944 in formalin-fixed paraffin- embedded (FFPE) samples and to find out relationship between miRNA expression and HR-HPV infection using reverse transcription-quantitative polymerase chain reaction (RT-qPCR). In this study, HR-HPV infection was determined by RT-qPCR targeting E6/E7, oncogenes of HPV. 결과: In brief, the results from this study showed that the expression levels of miR-9, miR-21, miR-155, and miR-944 in FFPE cervical cancer tissues were higher than in normal tissues. Among four miRNAs, miR-21 expression levels in both HR-HPV E6/E7-positive cancer tissues and -negative cancer tissues were significantly up-regulated. In other words, miR-21 expression level was up-regulated regardless of HR-HPV E6/E7 expression levels. In conclusion, this study seems to suggest that four miRNAs were up-regulated in cervical cancer tissues compared to normal tissues. 결론: Therefore, miR-9, miR-21, miR-155 and miR-944 seem to can be useful biomarkers for the diagnosis of cervical cancer.
Dawn Jung,Ji Eun Jung,Chang Moo Kang 대한내시경로봇외과학회 2023 Journal of Minimally Invasive Surgery Vol.26 No.2
Most familial adenomatous polyposis (FAP) patients undergo total colectomy, but duodenal polyposis develops in up to 90% of patients with FAP and a 4% to 18% risk of duodenal and ampullary cancer remains. Laparoscopic pancreas-preserving near total duodenectomy is thought to be a potential option and can be an effective approach to preserve the pancreas. A 48-year-old male patient, who underwent laparoscopic total colectomy with end ileostomy because of FAP with colorectal cancer, was diagnosed with a 20 mm-sized duodenal adenoma in the second to the third portion. The operation was performed on December 27, 2021. Near total duodenectomy was done and type II Billroth gastrojejunostomy was done. Laparoscopic pancreas-sparing duodenectomy is shown to be safe, with favorable short-term oncologic outcome compared to laparoscopic pancreatoduodenectomy in terms of less blood loss, faster recovery time, and much less total cost.
The Validation of MicroRNA Profiling in Fromalin-Fixed, Paraffin-Embedded Ovarian Cancer Sample
( Dawn Chung ),( Ga Won Lim ),( Sunghoon Kim ),( Sang Wun Kim ),( Young Tae Kim ),( Eun Ji Nam ) 대한산부인과학회 2012 대한산부인과학회 학술대회 Vol.98 No.-
MicroRNAs are known as non-coding RNA molecules working for post-transcriptional regulation with critical biologic functions including differentiation, proliferation, apoptosis and stress resistance of cell. Owing to the unique riboregulatory function of gene expression, global microRNA profiling of human malignancies, especially extracted from formalin-fixed, paraffin-embedded (FFPE) samples, are increasingly carrying out. To assess the validation of FFPE ovarian cancer tissues for microRNA profiling, we compared the expressions of several microRNAs of FFPE samples of ovarian cancer to that of matched fresh-frozen samples. Three patients operated for benign uterine disease (control group) and five patients diagnosed with serous ovarian carcinoma between June 2009 and October 2011 were enrolled. Profiling of microRNAs of each patient`s FFPE samples and matched fresh-frozen samples were performed using DNA microarray. Then the expression of eight over-regulated microRNAs and six down-regulated microRNAs were quantitatively analyzed by real-time PCR. Among eight over-regulated microRNAs, six microRNAs were demonstrated more than control group as a same pattern in both FFPE and matched fresh-frozen sample. All the six down-regulated microRNAs were less demonstrated as a same pattern in both samples. The profiling of microRNA in fromalin-fixed, paraffin-embedded ovarian cancer sample is valid as fresh-frozen sample.