Distribution of Knowledge through Online Learning and its Impact on the Intellectual Potential of PhD Students

Dana KANGALAKOVA(Dana KANGALAKOVA ),Aisulu DZHANEGIZOVA(Aisulu DZHANEGIZOVA ),Zaira T. SATPAYEVA(Zaira T. SATPAYEVA ),Kuralay NURGALIYEVA(Kuralay NURGALIYEVA ),Anel A. KIREYEVA(Anel A. KIREYEVA ) 한국유통과학회 2023 유통과학연구 Vol.21 No.4

Purpose: the research aims to analyze the impact of the distribution of knowledge through online learning on the intellectual potential of PhD students and produce recommendations for policy to improve intellectual capacity. During the literature review, it was determined that a large number of studies examined the impact of online learning on the quality of education at different levels. Research design, data and methodology: the research methodology is based on subjective assessment and studying the students’ opinions. The basis of the study was a comprehensive analysis of primary data obtained through a sociological survey of PhD students. 324 respondents from humanitarian, medical and natural faculties participated in the survey. Results: the study revealed that online learning helps increase students’ intellectual potential. PhD students had a positive attitude towards the transition from traditional education to online learning. It should be noted that, according to the results, the most popular gadgets were laptops and smartphones, which were characterized by high mobility and ease of use. Based on the obtained results, recommendations were developed for the formation of online learning with a focus on increasing students’ intellectual potential. Conclusions: based on the results of the assessment of educational and innovative potential, policy recommendations and further research in this area were proposed.

기독교 세계화 동향: 1945년 그 이후

Dana Robert,이연성 현대기독교역사연구소 2003 성결교회와 신학 Vol.9 No.-

Human Immunodeficiency Virus Infection and the Endocrine System

Dana Zaid,Yona Greenman 대한내분비학회 2019 Endocrinology and metabolism Vol.34 No.2

In the current era of effective antiretroviral therapies (ARTs), human immunodeficiency virus (HIV) infection became a chronic disorder that requires long term follow-up. Among other medical issues, these patients may develop endocrine problems, specific to HIV infection and its treatment. The purpose of this review is to give an overview of common endocrine complications associated with HIV infection, and to propose diagnostic and therapeutic strategies. HIV can affect the endocrine system at several levels. Adrenal and gonadal dysfunction, osteoporosis with increased fracture risk, dyslipidemia with increased cardiovascular risk, are some of the endocrine disorders prevalent in HIV-infected patients that may negatively influence quality of life, and increase morbidity and mortality. While ARTs have dramatically increased life expectancy in the HIV-infected population, they are not devoid of adverse effects, including endocrine dysfunction. Physicians caring for HIV-infected patients should be knowledgeable and exercise a high index of suspicion for the diagnosis of endocrine abnormalities, and in particular be aware of those that can be life threatening. Endocrine evaluation should follow the same strategies as in the general population, including prevention, early detection, and treatment.

Preparation of Bioactive Kefir with Added Flaxseed (Linum usitatissimum L.) Extract

( Dana Jeong ),( Dong-hyeon Kim ),( Jung-whan Chon ),( Kwang-young Song ),( Hyunsook Kim ),( Kun-ho Seo ) 한국유가공기술과학회 2017 Journal of Dairy Science and Biotechnology (JMSB) Vol.35 No.3

Flaxseed (Linum usitatissimum L.) is an important food, oil, and fiber crop of the family Linaceae. Although flaxseed has been consumed as a food ingredient for several centuries, its nutritional benefits have not yet been completely established. Flaxseed is a good source of lignans, nonstarch polysaccharides, and high-quality proteins. Hence, in this study, we aimed to prepare a bioactive kefir containing flaxseed and to examine the physicochemical characteristics of kefir containing different concentrations of flaxseed. We investigated the pH, and sensory evaluation of bioactive Kefir containing different concentrations of flaxseed. We investigated the pH, total anthocyanins (TAs), and sensory evaluation of bioactive Kefir containing different concentrations of flaxseed. The pH of this bioactive kefir decreased, whereas the TA content increased with increasing incubation time; however, these parameters were not affected by the amount of added flaxseed. As the addition rate of flaxseed increased, the scores for overall acceptability, texture, color, flavor, and taste in sensory evaluations were generally the same as or lower than the control. There were no significant differences in overall acceptability, texture, color, flavor, and taste between the control and treated groups. Therefore, further studies are needed to develop methods for production of health-improving kefir as a dietary supplement based on the functional properties of flaxseed.

Elisabetta Porcu and Michael Dylan Foster (ed.), Matsuri and Religion: Complexity, Con-tinuity, and Creativity in Japanese Festivals. Leiden: Brill, 2021, 332 pp. ISBN: 978-90-04-46652-4, €74 (pbk)

Dana MIRSALIS DAOS(The Daesoon Academy of Sciences) 2023 Journal of Daesoon Thought and the Religions of Ea Vol.2 No.2

Fabrication of a three-dimensional bone marrow niche-like acute myeloid Leukemia disease model by an automated and controlled process using a robotic multicellular bioprinting system

Dana M. Alhattab,Ioannis Isaioglou,Salwa Alshehri,Zainab N. Khan,Hepi H. Susapto,Yanyan Li,Yara Marghani,Arwa A. Alghuneim,Rubén Díaz-Rúa,Sherin Abdelrahman,Shuroug AL-Bihani,Farid Ahmed,Raed I. Felim 한국생체재료학회 2023 생체재료학회지 Vol.27 No.00

Background Acute myeloid leukemia (AML) is a hematological malignancy that remains a therapeutic challenge due to the high incidence of disease relapse. To better understand resistance mechanisms and identify novel therapies, robust preclinical models mimicking the bone marrow (BM) microenvironment are needed. This study aimed to achieve an automated fabrication process of a three-dimensional (3D) AML disease model that recapitulates the 3D spatial structure of the BM microenvironment and applies to drug screening and investigational studies. Methods To build this model, we investigated a unique class of tetramer peptides with an innate ability to selfassemble into stable hydrogel. An automated robotic bioprinting process was established to fabricate a 3D BM (niche-like) multicellular AML disease model comprised of leukemia cells and the BM’s stromal and endothelial cellular fractions. In addition, monoculture and dual-culture models were also fabricated. Leukemia cell compatibility, functionalities (in vitro and in vivo), and drug assessment studies using our model were performed. In addition, RNAseq and gene expression analysis using TaqMan arrays were also performed on 3D cultured stromal cells and primary leukemia cells. Results The selected peptide hydrogel formed a highly porous network of nanofibers with mechanical properties similar to the BM extracellular matrix. The robotic bioprinter and the novel quadruple coaxial nozzle enabled the automated fabrication of a 3D BM niche-like AML disease model with controlled deposition of multiple cell types into the model. This model supported the viability and growth of primary leukemic, endothelial, and stromal cells and recapitulated cell-cell and cell-ECM interactions. In addition, AML cells in our model possessed quiescent characteristics with improved chemoresistance attributes, resembling more the native conditions as indicated by our in vivo results. Moreover, the whole transcriptome data demonstrated the effect of 3D culture on enhancing BM niche cell characteristics. We identified molecular pathways upregulated in AML cells in our 3D model that might contribute to AML drug resistance and disease relapse. Conclusions Our results demonstrate the importance of developing 3D biomimicry models that closely recapitulate the in vivo conditions to gain deeper insights into drug resistance mechanisms and novel therapy development. These models can also improve personalized medicine by testing patient-specific treatments.

Modification of the unified BARGE method to measure the migration of phthalate esters from PVC products

Dana Fahad Mohamed Salman Moha,Du Yung Kim,Jinsung An,Jung-Hwan Kwon 환경독성보건학회 2022 한국독성학회 심포지움 및 학술발표회 Vol.2022 No.5

Rheology of Osteoarthritic Synovial Fluid Mixed with Viscosupplements: A Pilot Study

Dana Grecov,Petcharatana Bhuanantanondh,Ezra Kwok,Pierre Guy 대한의용생체공학회 2011 Biomedical Engineering Letters (BMEL) Vol.1 No.4

Purpose Osteoarthritis (OA) is a degenerative joint disease that is characterized by the breakdown of articular cartilage. Rheology of synovial fluid is of interest because of its significance in joint lubrication. However, there are still many questions related to synovial fluid rheology and its relation with OA. Although viscosupplementation has been used as a treatment for OA for many years, its clinical effect remains controversial. Therefore, the purpose of this study is to determine in vitro the effect of different viscosupplements on the rheological properties of synovial fluid. Methods A detailed rheological characterization of synovial fluid from 26 patients undergoing total knee arthroplasty (TKA) was performed. The rheological properties of the osteoarthritic synovial fluid added with viscosupplements were compared with those of the healthy human synovial fluid in order to assess the restorative effect on naturally occurring synovial fluid within the joint. Furthermore, the stability of rheological properties of synovial fluid mixed with viscosupplements in vitro over 8 weeks was analyzed. Results The addition of a cross-linked viscosupplement to OA synovial fluid was found to be more efficient than linear ones in improving the overall rheological properties of synovial fluid. The findings indicate that the rheological properties of SF mixed with VSs changed over 8 weeks. Conclusions The findings from this study will lead to a better understanding of the role of viscosupplements in joint lubrication and OA.

Uncertainty quantification for structural health monitoring applications

Dana E. Nasr,Wael G. Slika,George A. Saad 국제구조공학회 2018 Smart Structures and Systems, An International Jou Vol.22 No.4

The difficulty in modeling complex nonlinear structures lies in the presence of significant sources of uncertainties mainly attributed to sudden changes in the structure’s behavior caused by regular aging factors or extreme events. Quantifying these uncertainties and accurately representing them within the complex mathematical framework of Structural Health Monitoring (SHM) are significantly essential for system identification and damage detection purposes. This study highlights the importance of uncertainty quantification in SHM frameworks, and presents a comparative analysis between intrusive and non-intrusive techniques in quantifying uncertainties for SHM purposes through two different variations of the Kalman Filter (KF) method, the Ensemble Kalman filter (EnKF) and the Polynomial Chaos Kalman Filter (PCKF). The comparative analysis is based on a numerical example that consists of a four degrees-of-freedom (DOF) system, comprising Bouc-Wen hysteretic behavior and subjected to El-Centro earthquake excitation. The comparison is based on the ability of each technique to quantify the different sources of uncertainty for SHM purposes and to accurately approximate the system state and parameters when compared to the true state with the least computational burden. While the results show that both filters are able to locate the damage in space and time and to accurately estimate the system responses and unknown parameters, the computational cost of PCKF is shown to be less than that of EnKF for a similar level of numerical accuracy.

Bodies of Knowledge: Fat Studies, Fat Stigma, and Citizenship in U.S. Media Culture

( Dana Heller ) 한국영미문학페미니즘학회 2012 영미문학페미니즘 Vol.20 No.3

This essay explores the representation of the fat female body in contemporary U.S. media culture. It argues that the burgeoning interdiscipline of fat studies-as well as media images of fat women -have emerged as salient flashpoints for debate about gender, sexuality, race, ethnicity, class, and the proper parameters of citizenship. In the iconography of the mass media, the fat woman has long functioned as a site of palpable public anxiety about changes in the gendered social economy and the citizenship contract. However, some media texts challenge the stigma that is associated with fat. This essay discusses two of these texts, the television series Ugly Betty and the John Waters filmHairspray, to argue that the recent establishment of fat studies, and the positive resignification of fat women in U.S. popular culture, provides literary and media scholars with a unique opportunity to track the emergence of a new burgeoning “body” of knowledge regarding the meaning of citizenship.