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      • 信用 카드의 法的 性質에 관한 硏究

        崔埈璿,金大奎 全北大學校 1994 論文集 Vol.38 No.-

        A credit card is any card, plate, coupon book, or other single credit device that may be used from time to time obtain credit. This thesis is a study on the legal quality of credit cards, purporting to survey credit card transactions and find out suitable legal tools for solving disputes arising in connection with them. As of 1994, there were more than twenty-five million cardholder and turnover of 25,600 billion Won. The omnipotent credit card is used to get household commodities, services, tickets, hotel rooms, and whatever. In our country credit cards were first issued in 1969 by Shinsegae department store. Credit cards are now widely used. The card industry is appearing to promise to grow in the future owing to the increase in quantity. But there are many problems to be solved. The credit card system is viewed by many legal experts as way stations on the road to a cashless society. The credit card industry in Korea today is enjoying rapid success. The quantity of credit card sales is likely to continue increasing in the future due to spirited competition among the card issuers to get more cardholders and merchant members. The method of information protection for credit card is very significant. We should establish new laws for legal sanction to root up illegal lending through using credit card. We have to check the advertisement of card discount enterprises and promote sound awareness of use of cards. The best way to solve many problems with credit cards is to enact a comprehensive statute which covers various aspects of credit card transactions. If we use credit cards soundly, they will be a great motive to establish credit society earlier and set up a beautiful and rich credit society. The contents of this thesis are as follows ; introduction, history and notion of the credit card, legal quality and theory of credit card.

      • KCI등재

        공초점 원리를 이용한 3차원 표면형상 측정에 관한 연구

        강영준,송대호,유원재 한국비파괴검사학회 2001 한국비파괴검사학회지 Vol.21 No.2

        근대 산업에서 기계 부품들의 정밀도와 표면 마무리 조건은 그 어느 때보다 더 절박하게 요구되고 있는 가운데, 표면 형상의 측정과 이해는 공학 기술자뿐만 아니라 물리학자나 화학자도 높은 관심을 갖게 되었다. 이런 상황에서 광학적 측정 방법은 opto-mechatronics의 이점을 가지고 진동 측정이나 균열, 결함의 검출 등의 분야에서 유용한 측정 방법으로 사용되고 있고, 표면 형상학의 분야에서 다시 한 번 중요한 역할을 할 것으로 기대를 받고 있다. 본 연구에서는 공초점 현미경의 원리에 대해 서술하였고, 기존의 스캔 방식 공초점 현미경보다 한 차원 개선된 3차원 표면형상 측정 시스템을 개발하였다. 그리고, 표면의 기하적인 형상에 대한 정보를 얻고 그 형상을 가시화하기 위해 컴퓨터 시스템과 통합하고 그에 필요한 소프트웨어를 개발하였다. In modern industry, the accuracy and the surface-finish requirements for machined parts have been becoming ever more stringent. In addition, the measurement and understanding of surface topography is rapidly attracting the attention of the physicist and chemist as well as the engineer. Optical measuring method is used in vibration measurement, crack and defect detection with the advent of opto-mechatronics, and it is expected to play an important role in surface topography. In this study, the principle of confocal microscope is described, and the advanced 3-D surface measuring system that has better performance than the traditional confocal microscope is developed. Suitable fixtures are developed and integrated with the computer system for generating 3-D surface and form data. Software for data acquistion and analysis of various parameters in surface geometrical features has been developed.

      • 복막유착의 원인 규명과 예방을 위한 실험적 연구

        강대영,송규상,노승무,조준식,이태용 충남대학교 의과대학 지역사회의학연구소 1999 충남의대잡지 Vol.26 No.1

        Postoperative peritoneal adhesion is the most common cause of intestinal obstruction, and intestinal obstruction is one of the most difficult problems in abdominal surgery. In this experimental study for developing peritoneal adhesion model and its prevention, we divided rats into 5 groups; the talc powder treated group, the cotton-fluff treated group, the talc+fluff treated group, the ischemia group and the control group. There were 16 rats in each group. We made incisions on the midabdomen of the rats and administered talc powder, cotton fluff and talc powder+fluff into the peritoneal cavity respectively. In the ischemia group, we clamped the root of superior mesenteric artery for two minutes to induce ischemia on the small bowel of the rat. We counted the number of the peritoneal adhesive sites in peritoneal cavity on the 7th, 14th , 21st and 42nd postoperative day after peritoneal adhesion induced operation, and observed the characters of the adhesion state. The average number of the peritoneal adhesions were 1.25 per one rat in the talc powder group, 1.44 in the fluff group, 1.31 in the talc+fluff group and 1.31 in the ischemia group compared with 0.94 per one rat in the control group performed sham operation. 91.6% of the all adhesions were observed on the peritoneum of the previous incision sites and only 8.4% of the adhesions were adhered to the peritoneal surface of non-incision sites. The data of this study suggest that peritoneal injury and inflammatory reaction is the major cause of peritoneal adhesion. Also this study indicates that foreign bodies can develop peritoneal adhesion, but the effect is much lower than that of peritoneal injury with inflammatoty reaction.

      • 담관침습을 일으킨 간세포암과 간내 담관암의 감별 진단에 있어 조영제의 급속 정맥 주입방법을 이용한 동맥기 역동적 CT의 유용성 : Value of Arterial Phase Dynamic CT with a Higher Intravenous Injection Rate of Contrast Material

        조준식,김대홍 충남대학교 의과대학 지역사회의학연구소 1995 충남의대잡지 Vol.22 No.2

        PURPOSE : To evaluate the value of arterial phase dynamic computed tomography (CT) with a highs intravenous (IV) injection rate of contrast material in diagnosing hepatocellular carcinoma (HCC) with bile duct invasion mimicking intrahepatic cholangiocarcinoma (CAC). MATERIALS AND METHODS : Two-phase dynamic CT was performed in 19 patients with pa thologically proven HCCs (n=9) and CACs (n=10). Two-phase images were obtained at 20-50 sec (arterial phase) and 2-4 min (equilibrium phase) after the start of IV injection of contrast material (5 ml/sec, 150 ml). Two-phase images were compared and correlated with pathologic findings. RESULTS : On the arterial phase images, HCCs showed total heterogeneous hyperattenuation in all nine and CACs showed hvpoattenuation in seven and hypoattenuation with peripheral rim enhancement in three. On the equilibrium phase images, all HCCs showed hypoattenuation and capsular enhancement in four. However, all CACs showed hypoattenuation with peripheral or inhomogeneous isodense enhancement. Enhancement patterns of HCCs with bile duct invasion in the arterial phase were significantly different from that of intrahepatic CACs. CONCLUSION : Arterial phase dynamic CT with a higher IV injection rate of contrast material enables HCC with bile duct invasion to differentiate from intrahepatic CAC.

      • Rat의 복강내에 투여한 5-fluorouracil-polyglycolic acid 제형이 장기에 미치는 영향에 관한 연구

        강대영,송규상,최정목,노승무,정경수,오정연,김진향,양준묵,최선웅,이진호,조준식,민병무,김용백,김창식,박근성,김승영,김학용,인현빈 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

        For more effective intraperitoneal chemotherapy, the authers made 5-fluorouracil-polyglycolic acid composite disks(FU-PGA disks) with 5-fluorouracil and polyglycolic acid, a biodegradable polymer. We inserted the FU-PGA disk into the peritoneal cavites of Sprague-Dawley male rats, the control and three experimental groups; one FU-PGA disk insert group(300mg/kg), two FU-PGA disk insert group(600mg/kg), and three FU-PGA disk insert group(900mg/kg). The control group received a similar number of PGA disk inserts. A pharmacokinetic study was performed to measure the 5-fluorouracil concentration in the peritoneal fluid, blood, and tissues(liver, kidney and heart) at 24 hours, 72hours and 168 hours after insertion of the FU-PGA disk. Light and electron microscopic studies were done. The results were as follows: 1) The number of white blood cells and platelets decreased after FU-PGA insertion. The degree was proportional to the duration and amounts inserted. The change in the number of red blood cells varied slightly. 2) Light microscopically, slight changes were noted at 168 hours in the 3 disk insert group (900mg/kg). Mild fatty change and hepatocyte degeneration around the central veins of the liver were noted, with vacuolar degeneration in the proximal convoluted tubules of the kidney. 3) Electron microscopically,the liver showed focal increases of lipid droplets in the hepatocytes, and irregular nuclear membrane with focal nucleolar segregation of the fibrillar and granular elements. Also the double membranous structure of the hepatocytes and Kupffer cells was widened with bleb formation. The kidney showed wide separation of the nuclear double membrane in the proximal convoluted tubular cells and mesangial cells, with vacuolation and myelin figure formation in the mitochondria of the proximal convoluted tubular cells, at 72 hours and 168 hours in the 2 to 3 FU-PGA insert groups. The heart showed focal loss of cristae,vacuolation and myelin figure formation in the mitochondria of the 2 to 3 FU-PGA insert groups. In conclusion, despite the large amont of FU-PGA inserted, the histopathological changes in the liver, kidney and heart were slight, and consonant with the very low amount of 5-fluorouracil concentrations detected in the liver, kidney and heart. The above results suggest that the FU-PGA composite can serve as a new device for releasing drugs in a controlled manner and easily targeted to intraperitoneal organs. This device can improve the efficacy of intraperitoneal chemotherapy for gastric cancer.

      • 사군자탕이 L1210 세포를 이식한 마우스의 면역세포에 미치는 영향

        殷載淳,金大根,柳東和,權鎭,徐龍勳,蘇俊魯,全焄,吳贊鎬 우석대학교 의약품개발연구소 1997 藥學硏究誌 Vol.2 No.-

        The purpose of this research was to investigate effects of Sa-Kunja-Tang(SKT) on immune cells of L1210 cell-transplanted mice. The apoptosis and T lymphocytes subopoulation were tested using a flow cytometry, and the proliferation was tested using a MTT assay. Nitric oxide production from mouse peritoneal macrophage was tested using a Griess reagents, and the phagocytic activity of mouse peritoneal macrophage was tested using a lucigenin chemiluminescence. SKT suppressed apoptosis of T-lymphocytes induced by L1210 transplantation. SKT decreased nitric oxide production from mice peritoneal macrophages increased by L1210 transplantation, and the phagocytic activity decreased by L1210 transplantation. These results suggest that SKT suppresses T lymphocyte apoptosis and macrophage activity in L1210 transplanted mice.

      • 대장균에서 재조합 Rat Guanine deaminase 유전자의 발현, 정제 및 분석

        성연선,곽상준,박대성,김향원,이희영 단국대학교 1998 論文集 Vol.33 No.-

        Guanine deaminase(EC, 3.5.4.3, ;Guanine aminohydrolase, GAH, GDA) catalyzes the deamination reaction of guanine to xanthine irreversibly. The cDNA encoding rat guanine deaminase had been isolated from a λZAPII rat brain expression library using antibody generated against purified rat guanine deaminase. Toe obtain recombinant GDA and analyze the property of catalytically conserved retion, here we expressed the recombinant GDA in E.coli and showed the retention of its catalytic activity similar to native rat GDA. To make the construct carrying coding region to GDA in pGEX4T prokaryotic expression vector, the region encompassing open reading frame of pBlue-GDA was PCR amplified and subcloned into pGEX4T prokaryotic expression vector with correct reading frame of fusion carrier glutathione S-transferase. After transformation to E.coli DH5a. The bacteria carrying pGEX-GDA was grwon in the condition of IPTG induction. The fusion protein GST-GDA was purified with GSH-sepharose affinity chromatography. The purified GST-GDA was subsequently digested with biotin-conjugated thrombin, and thrombin was removed by streptavidin agarose. Then sample were treated with GSH-sepharose affinity chromatography to remove the contaminant GST and GST-GDA. The purified recombinant GDA showed 70% of specific activity relative to that of purified rat GDA. The recombinant GDA showed identical molecular weight with rat GDA in SDS-PAGE.

      • 사군자탕이 항암제를 투여한 마우스의 면역세포에 미치는 영향

        殷載淳,金大根,柳東和,權鎭,洪鍾星,蘇俊魯,全焄,吳贊鎬 우석대학교 의약품개발연구소 1997 藥學硏究誌 Vol.2 No.-

        The purpose of this research was to investigate effects of Sa-Kunja-Tang(SKT) on immune cells of antitumor drugs administered mice. The apoptosis and T lymphocytes subpopulation were tested using a flow cytometry, and the proliferation was tested using a MTT assay. The administration of etoposide. vincristine or doxorubicin increased the apoptosis of T-lymphocytes, but the action of doxorubicin was decreased by the administration of SKT. The administration of etoposide or vincristine decreased helper T and cytotoxic T cells population of T lymphocytes, but the action of vincristine was recovered by the administration of SCT. The administration of etoposide, vincristine or doxorubicin decreased the proliferation of T-lymphocytes, but the action of doxorubicin was increased by the administration of SKT. These results suggest that SKT has a regulative function of T-lymphocytes in anti-tumor drugs administered mice.

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