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사용자 사용성 향상을 위한 PC 게임 UI 디자인 연구 -오픈 월드(Open World Game) 게임을 중심으로-
최티에쥐 ( Cui Tian-ju ),이창욱 ( Lee Chang-wook ) 커뮤니케이션디자인학회 2023 커뮤니케이션 디자인학연구 Vol.84 No.-
본 연구는 컴퓨터 보급률 향상과 게임 시장의 산업화에 따라 최근 컴퓨터 게임 인터페이스 디자인의 중요성을 제시하고 오픈월드 게임의 사용성(usability) 평가에 따라 사용자와 만족도 간의 관계를 연구하고자 한다. 또한, 오픈월드 게임 사용자를 대상으로 사용자의 인터페이스 디자인이 게임에 끼치는 영향력을 이해하고, 오픈월드 게임 인터페이스 디자인 개선 방향에 대한 제시를 본 연구의 목적으로 한다. 이를 위해 먼저 선행연구를 통해 사용성 평가방법을 정리하고 스팀 매출 순위를 파악해 상위 3개 오픈월드 게임의 사용성을 평가하였다. 다음으로 게임의 주요 사용자인 20대를 대상으로 설문조사를 진행하여 오픈 월드 게임의 사용자 인터페이스 디자인의 문제점을 분명하게 밝히고, 각 게임마다 개선의 제안을 제시하였다. 마지막으로 본 연구를 통해 제시된 오픈월드 게임 사용 편의성 평가의 휴리스틱과 사용자 만족도는 효율성과 사용 편의성을 나타낸다. 따라서 이러한 평가방법은 향후 다른 장르의 PC게임에서 활용될 것으로 기대하는 바이다. This study presents the importance of computer game interface design in accordance with the increase in computer penetration rate and industrialization of the game market. This study aims to study the relationship between users and satisfaction according to the usability evaluation of open world games. Targeting open world game users, we tried to understand the influence of user interface design on the game. The purpose is to suggest a direction for improving the open world game interface design. First, the usability evaluation method was organized through preceding research, and the usability of the top three open world games was evaluated by identifying the steam sales ranking. In addition, the game's main users A survey was conducted on people in their twenties, and according to the survey, problems in the user interface design of open world games are clearly revealed, and suggestions for improvement are presented for each game. However, the open world games presented through this study The heuristic and user satisfaction of the usability evaluation can indicate efficiency and usability, and it is expected that this usability evaluation method will be used in other genres of PC games in the future.
Positive Association Between IL-16 rs11556218 T/G Polymorphism and Cancer Risk: a Meta-analysis
Mo, Cui-Ju,Peng, Qi-Liu,He, Yu,Wang, Jian,Xie, Li,Li, Tai-Jie,Li, Shan,Qin, Xue Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.11
Background: Interleukin-16 (IL-16) is a multifunctional cytokine which plays a key role in inflammatory and autoimmune diseases as well as in cancer. Genetic polymorphisms of IL-16 have been implicated in susceptibility to cancer. However, associations remain inconclusive. The present meta-analysis was therefore carried out to establish a more conclusive association of IL-16 polymorphisms with cancer risk. Materials and Methods: Relevant studies were searched through the PubMed, Embase, Web of Science, Google Scholar and Wan fang electronic databases updated in October 2013. Odds ratios (OR) and 95% confidence intervals (95% CI) were used to assess the association between IL-16 polymorphisms and cancer risk. Results: Eight eligible studies (rs4778889 T/C: 8, rs11556218 T/G: 7, rs4072111 C/T: 6) that met our selection criteria were included. The meta-analysis indicated that rs11556218 T/G was associated with a significant increased risk of cancer (G vs. T, OR=1.321, 95% CI=1.142-1.528, P<0.001; TG vs. TT, OR=1.665, 95% CI=1.448-1.915, P<0.001; GG+TG vs. TT, OR=1.622, 95% CI=1.416-1.858, P<0.001),as well as nasopharyngeal carcinoma and colorectal cancer. Furthermore, in the subgroup of Chinese, significant associations were found between rs11556218 polymorphism and cancer risk. There was no statistically significant association between the other two variants (rs4778889, rs4072111) and risk of cancer. Conclusions: This meta-analysis suggests that the IL-16 rs11556218 polymorphism is associated with increased cancer risk. Large well-designed studies involving various cancer types and different populations are now needed.
A High-speed Atomic Force Microscope for Precision Measurement of Microstructured Surfaces
Cui, Yuguo,Arai, Yoshikazu,Asai, Takemi,Ju, BinFeng,Gao, Wei Korean Society for Precision Engineering 2008 International Journal of Precision Engineering and Vol.9 No.3
This paper describes a contact atomic force microscope (AFM) that can be used for high-speed precision measurements of microstructured surfaces. The AFM is composed of an air-bearing X stage, an air-bearing spindle with the axis of rotation in the Z direction, and an AFM probe unit. The traversing distance and maximum speed of the X stage are 300 mm and 400 mm/s, respectively. The spindle has the ability to hold a sample in a vacuum chuck with a maximum diameter of 130 mm and has a maximum rotation speed of 300 rpm. The bandwidth of the AFM probe unit in an open loop control circuit is more than 40 kHz. To achieve precision measurements of microstructured surfaces with slopes, a scanning strategy combining constant height measurements with a slope compensation technique is proposed. In this scanning strategy, the Z direction PZT actuator of the AFM probe unit is employed to compensate for the slope of the sample surface while the microstructures are scanned by the AFM probe at a constant height. The precision of such a scanning strategy is demonstrated by obtaining profile measurements of a microstructure surface at a series of scanning speeds ranging from 0.1 to 20.0 mm/s.
Cui, Xiang-Shun,Li, Xing-Yu,Shen, Xing-Hui,Bae, Yong-Ju,Kang, Jason-Jongho,Kim, Nam-Hyung JOHN WILEY & SONS LTD 2007 MOLECULAR REPRODUCTION AND DEVELOPMENT Vol.74 No.2
<P>To gain insight into early embryo development, we utilized microarray technology to compare gene expression profiles in four-cell (4C), morula (MO), and blastocyst (BL) stage embryos. Differences in spot intensities were normalized, and grouped by using Avadis Prophetic software platform (version 3.3, Strand Genomics Ltd.) and categories were based on the PANTHER and gene ontology (GO) classification system. This technique identified 622 of 7,927 genes as being more highly expressed in MO when compared to 4C (P < 0.05); similarly, we identified 654 of 9,299 genes as being more highly expressed in BL than in MO (P < 0.05). Upregulation of genes for cytoskeletal, cell adhesion, and cell junction proteins were identified in the MO as compared to the 4C stage embryos, this means they could be involved in the cell compaction necessary for the development to the MO. Genes thought to be involved in ion channels, membrane traffic, transfer/carrier proteins, and lipid metabolism were also identified as being expressed at a higher level in the BL stage embryos than in the MO. Real-time RT-PCR was performed to confirm differential expression of selected genes. The identification of the genes being expressed in here will provide insight into the complex gene regulatory networks effecting compaction and blastocoel formation. Mol. Reprod. Dev. © 2006 Wiley-Liss, Inc.</P>
5-Lipoxygenase inhibitors suppress RANKL-induced osteoclast formation via NFATcl expression
( Ju Hee Kang ),( Zheng Ting ),( Mi Ran Moon ),( Jung Seon Sim ),( Jung Min Lee ),( Kyung Eun Doh ),( Sunhye Hong ),( Minghua Cui ),( Sun Choi ),( Hyeun Wook Chang ),( Hea Young Park Choo ),( Mijung Y 영남대학교 약품개발연구소 2016 영남대학교 약품개발연구소 연구업적집 Vol.26 No.-
5-Lipoxygenase synthesizes leukotrienes from arachidonic acid. We developed three novel 5-LO inhibi-tors having a benzoxazole scaffold as a potential anti-osteoclastogenics. They significantly suppressed RANKL-induced osteoclast formation in mouse bone marrow-derived macrophages. Furthermore, one compound. K7, inhibited the bone resorptive activity of osteoclasts. The anti-osteoclastogenic effect of K7 was mainly attributable to reduction in the expression of NFATc1. an essential transcription factor for osteoclast differentiation. K7 inhibited osteoclast formation via ERK and p38 MAPK. as well as NF-KB signaling pathways. K7 reduced lipopolysaccharide (LPS)-induced osteoclast formation in vivo. corroborating the in vitro data. Thus, IG exerted an inhibitory effect on osteoclast formation in vitro and in vivo, properties that make it a potential candidate for the treatment of bone diseases associated with excessive bone resorption.
Cui, Junjie,Kwon, Ji Eon,Kim, Hyeong-Ju,Whang, Dong Ryeol,Park, Soo Young American Chemical Society 2017 ACS APPLIED MATERIALS & INTERFACES Vol.9 No.3
<P>We synthesized two different amphiphilic small molecules 1 and 2 by attaching the same oligo(ethylene glycol) (OEG) unit to the same dicyanodistyrylbenzene (DCS) fluorophore but at different positions. These molecules self-assemble into nanoparticles in water and show lower critical solution temperature (LCST) at 26 and 58 degrees C, respectively. Upon heating, the transition of hydrophilic coils to hydrophobic globules of the OEG unit leads to the change in the stacking structure of the luminescent DCS cores. As a result, it shows significant ratiometric fluorescence color changes from excimeric yellow emission to monomer dominated green emission. Interestingly, the coassembly of 1 and- 2 exhibits single transition temperature between the transition temperatures of the two components. Moreover, it is demonstrated that the transition temperature of the coassembly is delicately tuned over 26-58 degrees C by varying the molar mixing ratio of them.</P>