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        Intradermal Therapy (Mesotherapy) for the Treatment of Acute Pain in Carpal Tunnel Syndrome: A Preliminary Study

        Conforti, Giorgio,Capone, Loredana,Corra, Stefano The Korean Pain Society 2014 The Korean Journal of Pain Vol.27 No.1

        Background: The carpal tunnel syndrome (CTS) is the most common cause of severe hand pain. In this study we treated acute pain in CTS patients by means of local intradermal injections of anti-inflammatory drugs (mesotherapy). Methods: In twenty-five patients (forty-five hands), CTS diagnosis was confirmed by clinical and neurophysiological examination prior to mesotherapy. A mixture containing lidocaine 10 mg, ketoprophen lysine-acetylsalycilate 80 mg, xantinol nicotinate 100 mg, cyanocobalamine 1,000 mcg plus injectable water was used. Sites of injection were three parallel lines above the transverse carpal ligament and two v-shaped lines, one at the base of the thenar eminence, and the other at the base of the hypothenar eminence. Results: The day after the treatment, all but four patients reported a significant reduction in pain and paresthesias. After 12 months, 17 patients had a complete pain relief, eight patients reported recurrence of pain and sensory symptoms and four out of them underwent surgical treatment. Conclusions: With the obvious limits of a small-size open-label study, our results suggest that mesotherapy can temporary relieve pain and paresthesias in most CTS patients and in some cases its effect seems to be long-lasting. Further controlled studies are needed to confirm our preliminary findings and to compare mesotherapy to conventional approaches for the treatment of CTS.

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        Intradermal Therapy (Mesotherapy) for the Treatment of Acute Pain in Carpal Tunnel Syndrome; A Preliminary Study

        ( Giorgio Conforti ),( Loredana Capone ),( Stefano Corra ) 대한통증학회 2014 The Korean Journal of Pain Vol.27 No.1

        Background: The carpal tunnel syndrome (CTS) is the most common cause of severe hand pain. In this study we treated acute pain in CTS patients by means of local intradermal injections of anti-inflammatory drugs (mesotherapy). Methods: In twenty-five patients (forty-five hands), CTS diagnosis was confirmed by clinical and neurophysiological examination prior to mesotherapy. A mixture containing lidocaine 10 mg, ketoprophen lysine-acetylsalycilate 80 mg, xantinol nicotinate 100 mg, cyanocobalamine 1,000 mcg plus injectable water was used. Sites of injection were three parallel lines above the transverse carpal ligament and two v-shaped lines, one at the base of the thenar eminence, and the other at the base of the hypothenar eminence. Results: The day after the treatment, all but four patients reported a significant reduction in pain and paresthesias. After 12 months, 17 patients had a complete pain relief, eight patients reported recurrence of pain and sensory symptoms and four out of them underwent surgical treatment. Conclusions: With the obvious limits of a small-size open-label study, our results suggest that mesotherapy can temporary relieve pain and paresthesias in most CTS patients and in some cases its effect seems to be long-lasting. Further controlled studies are needed to confirm our preliminary findings and to compare mesotherapy to conventional approaches for the treatment of CTS. (Korean J Pain 2014; 27: 49-53)

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        Wireless sensor networks for permanent health monitoring of historic buildings

        Zonta, Daniele,Wu, Huayong,Pozzi, Matteo,Zanon, Paolo,Ceriotti, Matteo,Mottola, Luca,Picco, Gian Pietro,Murphy, Amy L.,Guna, Stefan,Corra, Michele Techno-Press 2010 Smart Structures and Systems, An International Jou Vol.6 No.5

        This paper describes the application of a wireless sensor network to a 31 meter-tall medieval tower located in the city of Trento, Italy. The effort is motivated by preservation of the integrity of a set of frescoes decorating the room on the second floor, representing one of most important International Gothic artworks in Europe. The specific application demanded development of customized hardware and software. The wireless module selected as the core platform allows reliable wireless communication at low cost with a long service life. Sensors include accelerometers, deformation gauges, and thermometers. A multi-hop data collection protocol was applied in the software to improve the system's flexibility and scalability. The system has been operating since September 2008, and in recent months the data loss ratio was estimated as less than 0.01%. The data acquired so far are in agreement with the prediction resulting a priori from the 3-dimensional FEM. Based on these data a Bayesian updating procedure is employed to real-time estimate the probability of abnormal condition states. This first period of operation demonstrated the stability and reliability of the system, and its ability to recognize any possible occurrence of abnormal conditions that could jeopardize the integrity of the frescos.

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