http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
박길자 ( Cil Ja Park ),이미식 ( Mi Shick Lee ) 한국사회과교육학회 2002 시민교육연구 Vol.34 No.2
On This days many of social teacher use the movie. Movie is staff of teaching mothed. But meaning of movie is difficult. Because of the contents of the movie and the meanings carried by their messages are primarily complex. And movie do tend to reproduce interpretations which serve the interests of the ruling class, but they are `also a field of ideological struggle. Movie signification system is seen as relatively autonomous. The movie also serve `to reinforce a consensual viewpoint by using public idioms and by claiming to voice public opinion`. We concern about movie reading. First we studies what is movie reading. Next we concern about how student and teacher make sense of media texts. And we studies movie and social education. The end of reading movie and social education is critized that movie is thus portrayed as that of renewing, amplifying and extending the existing predispositions that constitute the dominant culture, not in creating them.
( Sung Cil Lim ) 한국응용약물학회 2013 Biomolecules & Therapeutics(구 응용약물학회지) Vol.21 No.5
Doxorubicin is still main drug in chemotherapy with limitation of use due to adverse drug reaction. Increased oxidative stress and alteration of nitric oxide control have been involved in cardiotoxicity of doxorubicin (DOX). A Disintegrin And Metalloproteinase (ADAMs) are transmembrane ectoproteases to regulate cell-cell and cell-matrix interactions, but role in cardiac disease is unclear. The aim of this study was to determine whether DOX activates peroxynitrite and ADAM 10 and thus ADAM and matrix metalloproteinase (MMP) induce cardiac remodeling in DOX-induced cardiomyopathy. Adult male Sprague-Dawley rats were subjected to cardiomyopathy by DOX (6 times of 2.5 mg/kg DOX over 2-weeks), and were randomized as four groups. Then followed by 3, 5, 7, and 14 days after cessation of DOX injection. DOX-injected animals signifi cantly decreased left ventricular fractional shortening compared with control by M-mode echocardiography. The expressions of cardiac nitrotyrosine by immunohistochemistry were signifi cant increased, and persisted for 2 weeks following the last injection. The expression of eNOS was increased by 1.9 times (p<0.05), and iNOS was marked increased in DOX-heart compared with control (p<0.001). Compared to control rats, cardiac ADAM10- and MMP 9- protein expressions increased by 20 times, and active/total MMP 9 proteolytic activity showed increase tendency at day 14 after cessation of DOX injection (n=10, each group). DOX-treated H9C2 cell showed increased ADAM10 protein expression with dose-dependency (p<0.01) and morphometric changes showed the increase of ventricular interstitial, nonvascular collagen deposition. These data suggest that activation of cardiac peroxynitrite with increased iNOS expression and ADAM 10-dependent MMP 9 expression may be a molecular mechanism that contributes to left ventricular remodeling in DOXinduced cardiomyopathy.
지속성장가능한(Sustainable) 학교경영을 위한 교육가치들의 영향 구조 분석
유길한 ( Cil Han Yoo ) 경북대학교 중등교육연구소 2013 중등교육연구 Vol.61 No.3
본 연구는 교사를 대상으로 다양한 교육가치들인 ‘교육 정치적 가치’, ‘교육 사회문화적 가치’, ‘교육 경제적 가치’, ‘교육 기술적 가치’들이 교사의 ‘지속가능한 교육발전 인식’, ‘지속가능한 교육만족 개선’, ‘지속가능한 학급경영 발전’ 요인을 통하여, ‘지속가능한 학교경영 발전’ 요인에 영향을 준다는 각 가설들에 대한 인과관계와 개발된 구조모델의 타당성을 검증하는 연구이다. 본 연구의 결과, 수정된 구조모델은 적합한 모델로서 받아들여 질 수 있으며, 이를 통한 연구결과는 다음과 같다. 첫째, 교육 경제적 가치 중, ‘경쟁의 가치’는 지속가능한 학교경영 발전에 가장 큰 긍정적 영향을 주고 있었다. 둘째, 교육 경제적 가치 중, ‘효율성의 가치’는 지속가능한 학교경영 발전에 긍정적 영향주고 있었다. 셋째, ‘교육 기술적 가치’는 지속가능한 학교경영 발전을 위하여 간접적 영향력이 매우 높은 것으로 나타났다. 마지막으로, 교육 정치적 가치인 ‘정부의 가치’와 ‘이해집단의 가치’에 대하여 학교 교사들은 유의미한 영향을 받지 않는 것으로 드러났다. 따라서 정부와 이해집단의 역할은 통제자와 압력행사자로서의 역할보다는 지원자, 평가자, 공정한 규칙을 만드는 사람으로서의 역할이 바람직한 것으로 판단된다. This research presents a comprehensive model of relationships between two political values in education, socio-cultural value in education, two economic values in education, technological value in education, sustainable educational development, sustainable educational satisfaction, sustainable classroom management, and sustainable school management. Structural equation modeling with AMOS was used to test a theoretical model with one sample that was comprised of 799 among 1060 samples of elementary teachers in Kyungsangnam-Do, Korea. To analyze the model, this study addresses complexity-laden sustainable school management issues with respect to teachers` perceptions of sustainable structure. After reviewing past research and using factor analysis, this research confirms the existence of ten latent variables in teachers` perception. The model developed has convergent validity, discriminant validity, and scale reliability. Finally, modeling techniques shows that the parameter estimates developed from the sample. In the model test, the final model fit was acceptable in considering almost model fit indices. Implications and directions for future research are discussed.
Chitin from Cuttlebone Activates Inflammatory Cells to Enhance the Cell Migration
Lim, Sung Cil,Lee, Ki-Man,Kang, Tae Jin The Korean Society of Applied Pharmacology 2015 Biomolecules & Therapeutics(구 응용약물학회지) Vol.23 No.4
Our previous report showed that the extract from cuttlebone (CB) had wound healing effect in burned lesion of rat and the extract was identified as chitin by HPLS analysis. We herein investigated the morphology in CB extract using scanning electron microscope (SEM). Chitin was used as a control. There is no difference in morphology between CB extract and chitin. We also assessed the role of CB extract on the production of inflammatory mediators using murine macrophages and the migration of inflammatory cells. The extract induced the production of nitric oxide (NO) in macrophages. While the extract of CB itself stimulated macrophages to increase the expression of pro-inflammatory cytokines such as tumor necrosis factor (TNF)-${\alpha}$, interleukin (IL)-$1{\beta}$, and IL-6, CB extract suppressed the production of those cytokines by LPS. CB extract also induced the production of mouse IL-8 which is related to the cell migration, and treatment with CB enhanced fibroblast migration and invasion. Therefore, our results suggest that CB activates inflammatory cells to enhance the cell migration.