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SDN‐based wireless body area network routing algorithm for healthcare architecture
Murtaza Cicioğlu,Ali Çalhan 한국전자통신연구원 2019 ETRI Journal Vol.41 No.4
The use of wireless body area networks (WBANs) in healthcare applications has made it convenient to monitor both health personnel and patient status continuously in real time through wearable wireless sensor nodes. However, the heterogeneous and complex network structure of WBANs has some disadvantages in terms of control and management. The software‐defined network (SDN) approach is a promising technology that defines a new design and management approach for network communications. In order to create more flexible and dynamic network structures in WBANs, this study uses the SDN approach. For this, a WBAN architecture based on the SDN approach with a new energy‐aware routing algorithm for healthcare architecture is proposed. To develop a more flexible architecture, a controller that manages all HUBs is designed. The proposed architecture is modeled using the Riverbed Modeler software for performance analysis. The simulation results show that the SDN‐based structure meets the service quality requirements and shows superior performance in terms of energy consumption, throughput, successful transmission rate, and delay parameters according to the traditional routing approach.
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Seden Demirci,Ayşe Aynalı,Kadir Demirci,Serpil Demirci,Buket Cicioğlu Arıdoğan 대한정신약물학회 2017 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.15 No.1
Objective: The present study aims to analyze the levels of resistin, tumor necrosis factor alpha (TNF-α), interleukin (IL)-1β, IL-6, IL-18, and C-reactive protein (CRP) in patients with Alzheimer’s disease (AD) and also investigate a potential relationship between resistin levels and TNF-α, IL-1β, IL-6, IL-18, and CRP levels in patients with AD. Methods: The study included fifty patients with AD and 30 healthy controls with normal cognitive functions. The serum resistin, TNF-α, IL-1β, IL-6, IL-18, and CRP levels were assessed. We performed a Mini-Mental State Examination (MMSE) to evaluate the general cognitive performance. Results: The mean serum resistin, IL-1β, IL-18, and TNF-α levels were significantly higher in patients with AD compared with the controls (p=0.026, p=0.002, p=0.003, and p=0.038, respectively). The IL-6 and CRP levels did not differ between the groups (p=0.874 and p=0.941). The resistin levels were positively correlated with the levels of CRP and IL-18 (r=0.526, p<0.001; r=0.402, p=0.004, respectively). MMSE scores and inflammatory markers were not correlated (p>0.05 for all). Conclusion: Serum resistin levels were significantly increased and correlated with some inflammatory markers in AD patients, suggesting that resistin might play a role in the inflammatory process of AD.
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