Imaging Anatomy of Waldeyer's Ring and PET/CT and MRI Findings of Oropharyngeal Non-Hodgkin's Lymphoma

Zhang, Chun-Xing,Liang, Long,Zhang, Bin,Chen, Wen-Bo,Liu, Hong-Jun,Liu, Chun-Ling,Zhou, Zheng-Gen,Liang, Chang-Hong,Zhang, Shui-Xing Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.8

Background: This study was conducted to analyze positron emission tomography (PET) / computed tomography (CT) and magnetic resonance imaging (MRI) performance with oropharyngeal non-Hodgkin's lymphoma (ONHL).Materials and Methods: The complete image data of 30 ONHL cases were analyzed, all patients were performed PET / CT and MRI examination before the treatment, with the time interval of these two inspections not exceeding 14 days. The distribution, morphology, MRI signal characteristics, enhancement feature, standardized uptake value (SUV) max value and lymph node metastasis way of the lesions were analyzed. Results: Among the 30 cases, 23 cases were derived from the B-cell (76.7%), 5 cases were derived from the peripheral T cells (16.7%) and 2 cases were derived from the NK/T cells (6.7%). 19 cases exhibited the palatine tonsil involvement (63.3%). As for the lesion appearance, 10 cases appeared as mass, 8 cases were the diffused type and 12 cases were the mixed type. 25 cases exhibited the SUVmax value of PET / CT primary lesions as 11 or more (83.3%). MRI showed that all patients exhibited various degrees of parapharyngeal side-compressed narrowing, but MRI still exhibited the high-signal fat, and the oropharyngeal mucosa was intact. 25 cases were associated with the neck lymph node metastasis, among who 22 cases had no necrosis in the metastatic lymph nodes, while the rest 3 cases exhibited the central necrosis in the metastatic lymph nodes. Conclusions: PET / CT and MRI have important value in diagnosing and determining the lesion extent of ONHL.

A Proteomic Analysis of Leaf Responses to Enhanced Ultraviolet-B Radiation in Two Rice (Oryza sativa L.) Cultivars Differing in UV Sensitivity

Xing-Chun Wu,Chang-Xun Fang,Jin-Yang Chen,Qing-Shui Wang,Ting Chen,Wen-Xiong Lin,Zhong-Liang Huang 한국식물학회 2011 Journal of Plant Biology Vol.54 No.4

To determine the proteomic response to UV irradiation, two cultivars, i.e., Lemont (UV tolerant) and Dular (UV sensitive), were exposed to natural and enhanced ultraviolet-B (UV-B) irradiation for 1, 7, and 14 days, and two-dimensional gel electrophoresis in combination with mass spectrometry (MS) and bioinformatics were used to compare the different proteomic responses in the leaves of the two cultivars. Thirty-nine proteins were up- or downregulated following the UV-B treatments. Among them, 30 increased or decreased more than 1.5-fold in abundance. They were further tested by using matrix-assisted laser desorption/ionization time of flight MS and performed a database search. Twentyfour proteins were thus identified. These identified proteins were mostly upregulated in Lemont, whereas only 14 of them upregulated in Dular. Nine proteins involved in glycometabolism and fatty acid metabolisms, signal transduction, and protein synthesis and folding in Dular were not changed. These results suggest that there was a complex regulative mechanism on the proteomes in rice leaves upon UV-B exposure.

RSS : A High-Performance Fault-Tolerant ATM Switch

Wen Tsuen Chen,Chun Fu Huang,Shui Yong Tseng 한국통신학회 1995 Asia-Pacific Conference on Communications Vol.2 No.1

Psychosocial Response and Symptom Burden for Male Smokers with Lung Cancer

Niu, Zhi-Min,Liang, Chun-Shui,Yu, Min,Wang, Yong-Sheng,Yu, Hai-Xia,Zhang, Qiong-Wen,Wei, Yu-Quan Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.1

Purpose: Cigarette smoking causes many kinds of cancer, and it is more closely related with lung cancer, rather than other cancers. Smoking is the leading cause of lung cancer and ninety percent of the smokers are male in China, but there is little published data concerning the psychological responses in the male smokers with lung cancer and its influence on the symptom burden. The aim of the study was to verify the hypothesis that male smokers with lung cancer have more positive attitude and less symptom burden, comparing to male non-smokers. Methods: A total of 194 men with cancer in West China Hospital, Sichuan, China, were assessed by self-administered questionnaire. Psychological response was measured by the Chinese version of Mini-Mental Adjustment to Cancer scale (Mini-MAC), and symptom burden was measured by the physical symptom distress scale from the Rotterdam Symptom Checklist (RSCL). Results: We found that smokers with lung cancer got higher scores in positive attitude and a smaller symptom burden than non-smokers. Patients with education lower than high school got higher scores of positive attitude compared to college graduate patients (p=0.038). Smokers with lung cancer who knew the potential carcinogenicity of cigarette showed less negative emotions (p=0.011). The psychological response was not affected by age, clinical stage, cell type, smoking duration and amount. Conclusions: Male smokers with lung cancer have a more positive attitude and fewer symptoms, comparing to male non-smokers. Appropriate psychological intervention for non-smokers with lung cancer deserves more attention.

An Experimental Model for Induction of Lung Cancer in Rats by Chlamydia Pneumoniae

Chu, De-Jie,Guo, Shui-Gen,Pan, Chun-Feng,Wang, Jing,Du, Yong,Lu, Xu-Feng,Yu, Zhu-Yuan Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.6

Objective: To assess induction effects of Chlamydia pneumoniae (Cpn) on lung cancer in rats. Methods: A lung cancer animal model was developed through repeated intratracheal injection of Cpn (TW-183) into the lungs of rats, with or without exposure to benzo(a)pyrene (Bp). Cpn antibodies (Cpn-IgA, -IgG, and -IgM) in serum were measured by microimmunofluorescence. Cpn-DNA or Cpn-Ag of rat lung cancer was detected through polymerase chain reaction or enzyme-linked immunosorbent assay. Results: The prevalence of Cpn infection was 72.9% (35/48) in the Cpn group and 76.7% (33/43) in the Cpn plus benzo(a)pyrene (Bp) group, with incidences of lung carcinomas in the two groups of 14.6% (7/48) and 44.2% (19/43), respectively (P-values 0.001 and <0.000 compared with normal controls). Conclusions: A rat model of lung carcinoma induced by Cpn infection was successfully established in the laboratory for future studies on the treatment, prevention, and mechanisms of the disease.

鍛辭成章: 「閱讀促進學習」教學法中筆記摘錄與共同建構在香港非華 語初中課堂的實踐與成效

Loh Ka Yee Elizabeth,Shum Shui Kee Mark,Lai Kwok Chang,Leung Tit Hei Nixon,Lam Ka Chun 단국대학교 한문교육연구소 2019 International Han-character Education Research Vol.1 No.1

최근 홍콩에서 중국어를 모국어로 사용하지 않는 학생들을 합격시킨 주류 중등학교들이 급증하고 있다.(2016, 입법회). 이 학교는 이러한 학생의 학습 차이를 고려하여 다양한 대처를 필요로 하고 있다. 다양한 방식을 채택하여 학생들이 중국어 학습을 잘 마칠 수 있게 지원하여, 그들의 진학이 구직난을 해소하고 사회 상류로의 진출 기회가 될 수 있도록 해야 한다.(Leung et al 2017; Loh & Tam, 2016). (중국은) 중국어를 사용하지 않는 학생들에게 적합한 중국어 교육법을 제공하 는 것이 필요하다고 판단하고 있으며, 이는 해결해야 할 급선무 문제가 되었다.(shum, 2015). 본 연구는 이러한 홍콩의 상황에 집중하였다. 「阅读促进学习」(Rose&Martin, 2012) 교수법은 비 중국어 사용자 학생들의 비율이 비교적 높은 중등학교 한 곳을 선정하고, 제2외국어 교육 과정을 중국어로 하는 대외한어교육현장에서 제 2외국어 학습 기관(홍콩교육국, 2014) 및 국제 일반 중등학교 교육 증서(IGCSE)의 교육과정 개요를 참조하여, 본 교육과정(커리큘럼)을 수정 하였다. 협업과 회의를 통해 공동으로 수업을 준비하고 교육현장을 관찰하는데, 교사와 학생들이 모인 소그룹 인터뷰, 필기 및 수업 원본 분석 등의 방법을 진행하였다. 이를 통해 본 교수법이 학생들에게 설명문 종류의 글을 읽고 쓰는 능력을 향상시키고 학습 동기를 높일 수 있는지의 여부를 검토하였다. 교사는 학생들이 본문을 자세하게 읽도록 한 후, 그룹 협업을 통해 그 문장에 서 핵심 키워드를 발췌하여 노트에 기록하도록 학생들을 지도하는 방법(Note Making)을 시행하고, 이어서 학생들은 상호 간의 교류와 협력에 의해 문장 속에 등장한 핵심 단어들과 구 형식, 문장 형식을 활용하여, 협업을 통해 새로운 글을 창작하고, 마지막으로 학생들이 각자 개별적으로 작문을 수행하게 하였다. 본 연구를 통해, 상술한 단계가 학생들이 문장 형식에 따른 다양한 언어 능력의 차이를 이해하도록 돕는데 효과적이며, 서로 다른 글쓰기 활동에 활용할 수 있음을 발견했다. 원전 분석 및 소그룹 인터뷰 또한 위 교수법이 학생들의 중국어 학습 동기를 향상시키는 데 효과가 있음과 학생들의 학습에 대한 믿음이 증가한 것을 보여주었다. 본 연구는 阅读促进学习 교수법이 학생들의 읽기와 쓰기 능력을 개선하고, 각 교육 절차의 실천적 성과들이 모두 시사성이 있음을 검증하였다는데 그 의의가 있다. In Hong Kong, the number of secondary schools admitting Non-Chinese Speaking (NCS) students has increased tremendously in recent years (LegCo, 2016), in which most of them are mainstream schools. To cater the learning differences of NCS students, various supportin g programs have been employed to help NCS students to improve their Chinese so as to ease their difficulties in applying for universities and finding jobs (Loh & Tam, 2016), and hence enhancing upward social mobility (Leung et al, 2017). Thus developing suitable Chinese as a Second Language (CSL) pedagogies has caught much scholarly attention with pressing needs. Under such backdrop, the paper discusses the use of “Reading to Learn (R2L)” Pedagogy (Rose & Martin, 2012) to support the junior secondary CSL teaching and learning in a secondary school with high NCS density. The research team developed school-based teachin g and learning materials based on Chinese Language Curriculum Second Language Adapted Learning Framework (EDB, 2014) and International General Certificate of Secondary Educat ion (IGCSE) syllabus. Based on collaborative lesson preparation, class observation, teachers and students focus groups, close examination of students’work, the study aims at finding the effectiveness of R2L in enhancing students’ reading and writing abilities of explanatory essays, as well as their motivation. Through Detailed Reading, Note-making, Joint Rewriting and Joint Construction, with extensive scaffolding and teacher-student interaction, students are able to understand the register variables and transfer to individual writing of explanatory essays. Discourse analysis and focus group interviews also show that R2L can enhance the motivation of students and their confidence in learning Chinese. The study explores the potential of applying R2L pedagogy to enhance the reading and writing of explanatory essay s, as well as discerning the praxis and effectiveness of various teaching stages.

Numerical And Sensitivity Analysis of Bearing Reinforcement Earth (BRE) Wall

Cherdsak Suksiripattanapong,Suksun Horpibulsuk,Avirut Chinkulkijniwat,Jin Chun Chai,Shui-Long Shen,Arul Arulrajah,Apichat Suddeepong 대한토목학회 2017 KSCE JOURNAL OF CIVIL ENGINEERING Vol.21 No.1

Numerical and sensitivity analysis of the Bearing Reinforcement Earth (BRE) wall were carried out using PLAXIS 2D. The numerical and sensitivity analysis was performed by varying the foundation conditions (thickness, T and modulus of elasticity, E of the weathered crust) and the BRE wall properties (number of transverse members, n, reinforcement length, L, wall height, H, reinforcement vertical spacing, Sv and axial stiffness of reinforcement, EA). The studied L/H ratio is between 0.7 and 1.0 and the geotextiles elements were used to model the reinforcement. The settlement of the BRE wall is governed by E, T, and H, irrespective of the BRE wall properties. The bearing stress distribution is essentially the same even with different E, T, n, Sv, EA. The magnitude of bearing stress is mainly controlled by H. The lateral movement pattern is primarily dependent upon Sv for a particular H. The inward movement exists for small Sv value while the outward movement exists for large Sv value. The magnitude of lateral movement is controlled by E, T, L and n. For a particular foundation condition (E and T), an increase in n is more advantageous than an increase in L because the lateral movement is insignificantly reduced when L/H > 0.8. The maximum tension and AASHTO recommended failure plane were found not to coincide in the serviceability state. In the serviceability state, the tie points must be stronger than the reinforcements for the wall height > H/2 while the reinforcement must be stronger than the tie point for the wall height < H/2. The simplified K versus H relationship is a practical tool to examine the factor of safety based on the conventional method.

Clinical Analysis of Stages of HBV Infection in 100 Cases of Lymphoma

Tang, Yang,Sun, Li-Guang,Liu, Chun-Shui,Li, Yu-Ying,Jin, Chun-Hui,Li, Dan,Bai, Ou Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.2

Objective: HBV infection may cause damage to the immune system and induce lymphomas as a result. Some scholars have indicated that HBsAg(+) reflecting HBV infection may have a relationship with lymphoma development. This study was designed to find out the specific stage of HBV infection which may be related to lymphoma. Methods: HBV serum markers, including HBsAg, HBsAb, HBeAg, HBeAb, HBcAb were tested among 100 lymphoma patients and 100 other patients who were diagnosed with non-lymphoma diseases in the First Hospital of Jilin University from 2010.1.1 to 2012.12.31. Three subgroups were established depending on different combinations of HBV serum markers. Subgroup 1 was HBsAg(+) representing the early stage of HBV infection. Subgroup 2 was HbsAb(+) representing convalescence and Subgroup 3 was "HbsAg and HbsAb negative combined with other positive markers" representing the intermediate stage of HBV infection. Chi square tests were used to compare the rates of three subgroups in lymphoma and control groups. Results: The rates of Subgroup were 13% and 5% respectively, an association between HBsAg and lymphoma being found (P<0.05). There was no difference between rate of Subgroup 2 of lymphoma group (15%) and that of control group (16%). In lymphoma group and control group, the rate of Subgroup 3 was different (12% vs 4%). This evidence was not specific to T cell lymphoma, B cell lymphoma or Hodgkin's lymphoma. Conclusions: Among serum markers of HBV, the combination of serum markers representing the early stage and intermediate stage of HBV infection have a relationship with lymphoma. Convalescence from HBV infection appears to have no relationship with lymphoma.

Distribution of secretory phospholipase A2 XIIA in the brain and its role in lipid metabolism and cognition.

Ee, Sze-Min,Lo, Yew-Long,Shui, Guanghou,Wenk, Markus R,Shin, Eun-Joo,Kim, Hyoung-Chun,Ong, Wei-Yi Humana Press 2014 Molecular Neurobiology Vol.50 No.1

<P>Phospholipases A(2) (PLA(2)) catalyze the hydrolysis of membrane phospholipids to produce free fatty acids and lysophospholipids, which have important functions in cell signaling. The present study elucidated differential expression of PLA(2) isoforms in the rat cortex by quantitative reverse transcription PCR and demonstrated that sPLA(2)-XIIA had greater messenger RNA expression than iPLA(2)-VI or cPLA(2)-IVA in different brain regions, or compared to other sPLA(2) isoforms in the prefrontal cortex (PFC) and hippocampus. Western blots identified a 24-kDa band in different regions of the adult brain, and high levels of sPLA(2)-XIIA protein expression were detected in the PFC, striatum, and thalamus. Electron microscopy showed that sPLA(2)-XIIA is present in axon terminals and dendrites. Injection of antisense oligonucleotide to sPLA(2)-XIIA in the PFC and lipidomic analysis showed increase in phospholipid but decrease in lysophospholipid species consistent with decreased catalytic activity of the enzyme, changes in arachidonic acid release, and alterations in sphingolipids. sPLA(2)-XIIA knockdown also resulted in shorter latency timings in the passive avoidance test, and higher number of errors in the attention set-shifting task, indicating deficits in working memory and attention. Together, the results show an important role of sPLA(2)-XIIA in lipid metabolism, prefrontal cortical function, and cognition.</P>

The antimicrobial activity of as-prepared silver-loaded phosphate glasses and zirconium phosphate

Wang Jing,Ji Zhi Jiang,Shui Zhong He,Yang Yang,Zhao Chun Yan,Wang Xiao Yan 한국화학공학회 2016 Korean Journal of Chemical Engineering Vol.33 No.3

The antimicrobial activities of silver-loaded zirconium phosphate (JDG) and silver-loaded phosphate glasses (ZZB) against Escherichia coli were studied. Although the silver content in JDG was higher than that in ZZB, ZZB suspensions showed better antimicrobial property than JDG suspensions, especially at low concentrations. The antimicrobial activity was analyzed using minimum inhibitory concentrations, bacterial inhibition ring tests, and detection of silver ions in the suspensions. Furthermore, the amounts of silver ions in suspensions with/without bacterial cells were analyzed. Results revealed that only a portion of released silver ions could be adsorbed by E. coli cells, which are critical to cell death. The damaged microstructures of E. coli cells observed by transmission electron microscopy may further prove that the adsorbed silver ions play an important role in the antimicrobial process.