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Ying-Chu Chen,Chungsying Lu 한국공업화학회 2014 Journal of Industrial and Engineering Chemistry Vol.20 No.4
Multiwalled carbon nanotubes (MWCNTs) were modified by NaOCl solution and employed as adsorbents to study kinetics, thermodynamics and regeneration of molybdenum (Mo) adsorption from aqueous solutions. The amount of Mo adsorbed onto MWCNT(NaOCl) increased with increasing solution temperature indicating an endothermic reaction while the kinetics of Mo adsorption follows the pseudo-second-order rate law. The Mo ions could be efficiently desorbed from the surface of MWCNT(NaOCl) by 3.6 wt% NaOCl solution for 4 h. A comparative study on the cyclic Mo adsorption between MWCNT(NaOCl) and granular activated carbon (GAC) revealed that the MWCNT(NaOCl) possess higher capacity and less attrition of Mo adsorption through 10 cycles of adsorption and desorption. This suggests that the MWCNT(NaOCl) have good potential for Mo removal in wastewater treatment.
Chu-Chung Chou,Jai-Sing Yang,Hsu-Feng Lu,Siu-Wan Ip,Chyi Lo,Chih-Chung Wu,Jing-Pin Lin,Nou-Ying Tang,Jing-Gung Chung,Ming-Jen Chou,Ying-Hock Teng,Dar-Ren Chen 대한약학회 2010 Archives of Pharmacal Research Vol.33 No.8
Dietary polyphenols have been correlated with a reduced risk of developing cancer. Quercetin (a natural polyphenolic compound) induced apoptosis in many human cancer cell lines, including breast cancer MCF-7 cells. However, the involvement of possible signaling pathways and the roles of quercetin in apoptosis are still undefined. The purpose of this study was to investigate the effects of quercetin on the induction of the apoptotic pathway in human breast cancer MCF-7 cells. When MCF-7 cells were treated with quercetin for 24 and 48 h and at various doses (10-175 μM), cell viability decreased significantly in time- and dose-dependent manners. Exposure of MCF-7 cells to 10-175 μM quercetin resulted in an approximate 90.25% decrease in viable cells. To explicate the mechanism underlying the antiproliferative effect of quercetin, cell cycle distribution and apoptosis in MCF-7 cells was investigated after exposure to 150 μM quercetin for 6-48 h. Quercetin caused a remarkable increase in the number of S phase (14.56%to 61.35%) and sub-G1 phase cells (0.1% to 8.32%) in a dose- and time-dependent manner. Quercetin caused S phase arrest by decreasing the protein expression of CDK2, cyclins A and B while increasing the p53 and p57 proteins. Following incubation with quercetin for 48 h, MCF-7 cells showed apoptotic cell death by the decreased levels of Bcl-2 protein and ΔΨ m and increased activations of caspase-6, -8 and -9. Moreover, quercetin increased the AIF protein released from mitochondria to nuclei and the GADD153 protein translocation from endoplasmic reticulum to the nuclei. These data suggested that quercetin may induce apoptosis by direct activation of the caspase cascade through the mitochondrial pathway in MCF-7 cells.
Stone weirs in Penghu and adaption to tourism development
Ying-Chien Chu,Shyi-Liang Yu,Chia-Wen Tsai 한국생태학회 2015 Journal of Ecology and Environment Vol.38 No.2
The ancient fishing methods include stone fish weir, beach seine and baulk net, but the fish catches of the stone fish weir is the most abundant. The stone fish weirs not only constitute important landscape, but also are representative of the fishery culture in Penghu, because they are fishing ground built by ancient people to take advantage of natural environment and resources. The objectives of this study is to understand the relevance of stone fish weirs in Penghu and to preserve biological diversity, as well as the value of stone fish weirs in Penghu fishery culture, and further make suggestions on the stone fish weirs. According to the present study, the marine species around the stone fish weirs tend to be diversifying, and in the future the region’s economy can be revitalized by sightseeing, which may promote the ecotourism, and also volunteer tourism. In the future, stone fish weirs must be promoted as a sightseeing destination. Also, by taking into consideration the experience of the Jibei stone weir protection team, the local communities of Penghu can have their own protection team to revitalize the stone fish weirs for sustainable operation and management.
Ran Chu,Penglin Liu,Jingying Chen,Xiaodong Cheng,Kezhen Li,Yanci Che,Jianliu Wang,Li Li,Xi Zhang,Shu Yao,Li Song,Ying Zhao,Changzhen Huang,Ying Xue,Xiyu Pan,Junting Li,Zhongshao Chen,Jie Jiang,Beihua 대한부인종양학회 2023 Journal of Gynecologic Oncology Vol.34 No.2
Objective: To evaluate the impact of bleomycin/etoposide/cisplatin (BEP) and paclitaxel/carboplatin (PC) chemotherapy regimens on the fertility and prognostic outcomes in malignant ovarian germ cell tumor (MOGCT) patients who underwent fertility-sparing surgery (FSS). Methods: A propensity score matching algorithm was performed between the BEP and PC groups. The χ2 test and the Kaplan-Meier method were used to compare the fertility outcome, disease-free survival (DFS) and overall survival (OS). The Cox proportional hazards regression analysis was used to identify risk factor of DFS. Results: We included 213 patients, 185 (86.9%) underwent BEP chemotherapy, and 28 (13.1%) underwent PC chemotherapy. The median age was 22 years (range, 8–44 years), and the median follow-up period was 63 months (range, 2–191 months). Fifty-one (29.3%) patients had a pregnancy plan, and 35 (85.4%) delivered successfully. In the before and after propensity score matching cohorts, there were no significant differences in spontaneous abortion, selective termination of pregnancy, during-pregnancy status, and live birth between the BEP and PC groups (p>0.05). Fourteen (6.6%) patients experienced recurrence, including 11 (5.9%) in the BEP group and 3 (10.7%) in the PC group. Four (1.9%) patients in the BEP group died. Kaplan-Meier analysis revealed no significant differences in DFS (p=0.328) and OS (p=0.446) between the BEP and PC groups, and the same survival results were observed in the after matching cohort. Conclusion: The PC regimen is as safe as the BEP regimen for MOGCT patients with fertility preservation treatment, and no differences were observed in fertility and clinical prognosis.
Regulation of meilingmycin in Streptomyces nanchangensis: Effect of ammonium ion
Ying-ping Zhuang,Yong Wang,Ping Wang,Ju Chu,Si-liang Zhang 한국화학공학회 2010 Korean Journal of Chemical Engineering Vol.27 No.3
Effects of different ammonium sulfate concentrations on meilingmycin biosynthesis were studied in this research. The results show that a lower concentration of ammonium ions stimulates the biosynthesis of meilingmycin,while a concentration higher than 5mmol/L inhibits the mycelial growth and the biosynthesis of the products. However,increased sugar consumption rate with the elevated concentration of ammonium sulfate was observed during the fermentation process. On this basis, six enzymes, which are responsible for the meilingmycin biosynthesis and the glucose metabolism, were measured and analyzed during the bioprocess. The results suggest that glucose-6-phosphate dehydrogenase, citrate synthase, succinate dehydrogenase and fatty acid synthase are stimulated by higher concentration of ammonium ions, while valine dehydrogenase and methylmalonyl-CoA carboxyltransferase are inhibited. From the results it follows that the precursor supply was restricted with the higher concentration of ammonium ions, which results in the lower production of meilingmycin. Thus, the strategy of maintaining a low level of FAS activity is a critical factor for high yield of meilingmycin.
Automatic Recognition of Emotion based on a Cognitively Motivated Emotion Annotation System
( Ying Chen ),( Sophia Yat Mei Lee ),( Chu Ren Huang ) 서울대학교 인지과학연구소 2011 Journal of Cognitive Science Vol.12 No.3
Emotion recognition is very important for the extraction of expressive information. In this paper, we provide a robust and versatile emotion annotation scheme that can not only annotate explicit and implicit expressions of emotion, but also can encode different levels of information for a given emotion content. In addition, taking cognitive psychologists` theories into account, large and comparatively high-quality emotion corpora are automatically created to allow for emotion recognition in Chinese and English. Our annotation scheme can easily be adapted for different kinds of applications dealing with emotion, and, being generic, can also be applied to other languages, We also discuss the two kinds of emotion representations used in our corpus, namely, holistic and componential representations, We find that the two representations have their own qualities and shortcomings and that choosing between them ultimately depends mainly on the application type.