유구치 와동형성이 아말감 파절에 미치는 영향에 관한 연구

하대송,김종관,이종갑 大韓小兒齒科學會 1984 大韓小兒齒科學會誌 Vol.11 No.1

In this experiments, the fracture loads were measured and analysed by using of Instron universal testing machine (Model 1132). With 80 upper and lower deciduous molars that were free of dental caries. Isthmus of teeth were prepared to 1/3 and 1/4 of intercuspal width, and internal line angles with round and sharp shape, and then amalgam restoration were performed. The results of this study were as follows; 1. Resistance to fracture loads were greater with isthmus of 1/3 intercuspal width than of 1/4 intercuspal width, especially, statistically significant difference on upper and lower second deciduous molars. 2. Resistance to fracture loads were greater with rounded internal line angle than sharp internal line angle. The above results were as follows, the fracture loads had greater resistance on isthmus of 1/3 intercuspal width, and rounded internal line angle, but normal physiological occlusal forces could permit isthmus of 1/4 intercuspal width and rounded internal line angle.

산딸나무 열매로부터 저밀도 지질 단백질(LDL) 산화 역제물질의 분리

이대영,송명종,김민정,정낙훈,정태숙,이윤형,백남인 경희대학교식량자원개발연구소 2007 硏究論文集 Vol.26 No.1

산딸나무 열매를 100% MeOH로 추출하고, 얻어진 추출물을 EtOAc, n-BuOH 및 물로 용매 분획 하였다. 이 중 EtOAc 분획으로부터 silica gel과 octadecyl silica gel(ODS) column chromatography를 반복하여 1종의 lignan 화합물을 분리, 정제하였다. 화합물의 화학구조는 NMR, Ms 및 IR 등의 스펙트럼 데이터를 해석하여, (+)-pinoresinol (1) 로 동정하였다. 이 화합물은 산딸나무에서 처음 분리되었다. LDL-항산화활성 억제활성이 20㎍/mL 처리농도에서 85.1±1.3%로 나타났다. (+)-Pinoresinol was isolated from the EtOAc fraction of methanol extracts of the fruits of Cornus kousa Burg. The chemical structures of (+)-pinoresinol was determined by spectroscopy method, as well as 1D- and 2D-NMR (^(1)H-^(1)H COSY, HSQC and HMBC) spectroscopy. This compound was the first to be isolated from C. kousa Burg. Also, (+)-pinoresinol inhibited LDL-oxidation with the inhibitory activity of 85.1±1.3% at a concentration of 20 ㎍/mL.

蠶兒의 部位別 神經球摘出이 絹絲 腺發育 및 絲質에 미치는 影響

李鍾哲,裵啓宣,崔雲浹,孫興大 東亞大學校 1977 東亞論叢 Vol.14 No.-

家蠶을 5齡起蠶과 熟蠶때에 腹部 第 2,4,6 神經球를 摘出하여 絹絲線發育, 吐絲量, Fibroin 含量比, 營繭形態 및 ??體色의 變化에 대해 試驗하였던 바 그 結果는 다음과 같다. 1. 絹絲線의 發育은 腹部 第 4,6 神經球 摘出보다 腹部 第 2 神經球 摘出이 더 크다. 2. 各 神經球 摘出은 絹絲線의 屈曲現像을 보였다. 3. 吐絲量은 腹部 第 4,6 神經球 摘出보다 腹部 第 2 神經球 摘出이 적었다. 4. 絹絲線의 發育정도와 吐絲量은 같은 傾向을 보였다. 5. 繭絲의 Fibroin 含量比는 腹部 第 6 神經球 影響이 腹部 第 2,4 神經球보다 큰 것 같다. 6. 神經球 摘出의 경우 表面의 營繭形態는 薄皮營繭이었고 腹部 第 4 神經球 摘出의 裏面의 營繭形態는 대부분 ??體半露出繭을 나타내었다. 7. 腹部 第 2,4,6 神經球는 化?? 및 ??體色의 變化에 關與할 可能性이 예상되며 앞으로 硏究할 必要가 있다고 본다. 8. 腹部 第 6 神經球는 排糞機能에 影響을 미친다. This experiment was conducted to investigate the effects of Silkgland growth, Spinning quantity, Fibroin Component ratio, Cocooning shape and changing the pupa coloration by resecting abdominal 2nd, 4th and 6th ganglia at both the time of 5 instar awakened larva and matured larva in silkworm. The results were summarized as follows: 1. Silkland growth was showed that resecting abdominal 2nd ganglion was more effective than those of abdominal 4th and 6th ganglia. 2. The shape of silkland was appeared as serpentining by resecting ganglia. 3. Spinning quantity was revealed that resecting abdominal 2nd ganglion was less than those of abdominal 4th and 6th ganglia. 4. Silkland growth and spinning quantity were revealed the same tendency in degree of increase. 5. Fibroin Component ratio of brave was seemed that abdominal 6th ganglion was moe effective than abdominal 2nd and 4th ganglia. 6. In the case of resecting ganglia, flimsy cocoon was formed at upper parts of cocoon and half of pupa body was mostly observed staying outside of cocoon in the cocoon shape at lower part of abdominal 4th ganglia. 7. Abdominal 2nd, 4th and 6th ganglia were expected to have a close connection with pupation and changing the pupa coloration. 8. Furction of evacuation was seemed to be controlled by abdominal 6th ganglia.

피칸(Carya illinoensis C. KocH)으로부터 지질대사물질의 분리 및 동정

송명종,한민우,양혜정,이대영,노영덕,백남인 경희대학교식량자원개발연구소 2007 硏究論文集 Vol.26 No.1

피칸(Carya illinoensis C. Koch) 열매를 80% MeOH로 추출하고, 추출물을 극성에 따라 n-hexane, CHCl_(3), EtOAc, n-BuOH 및 물로 분배, 추출하였다. 이 중 EtOAc분획으로부터 silica gel column chromatography를 반복하여 4종의 지질화합물을 분리하였다. 분리된 화합물 화학구조는, NMR 및 MS 등의 스펙트럼을 해석하여 oleic acid methyl ester, linoleic acid methyl ester, β-sitosterol, daucosterol(3-O-β-D-glucopyaranosyl β-sitosterol)으로 동정하였다. Carya illinoensis C. Koch was extracted with 80% aqueous MeOH, and the concentrated extract was partitioned with n-hexane, CHCl_(3), EtOAc, n-BuOH and H_(2)O, successively. From the EtOAc fraction, four compounds were isolated through the repeated silica gel column chromatographies. From the results of physico-chemical data including NMR, MS and IR, the chemical structures of the compounds were determined as oleic aicd methyl ester(1), linoleic aicd methyl ester(2), β-sitosterol(3), and daucosterol(4). They were the first to be isolated from C. illinoensis.

한국산 뱀독이 개구리 심방근 수축에 미치는 효과

한종희,방효원,엄대용,이상돈 중앙대학교 의과대학 의과학연구소 1984 中央醫大誌 Vol.9 No.1

In order to observe the effect of freeze-dried saliva of Korean venomous snake, Agkistrodon blomhoffii brevicaudus, on the contractility of spontaneously beating frog atrial muscle, a muscle strip was prepared and immersed in a vertical force recording chamber in frog Ringer solution containing 10^-7M propranolol. Isometric contraction was recorded and the following results wers obtained. 1. Developed tension of an atrial muscle strip increased with the increase of external calcium ion concentration, from 0.66mM up to 3.3mM but little change was observed in spontaneously beating frequency. 2. Inverse relationship was observed between the contractility and its driving frequency in venomtreated group. 3. The contractility decreased slightly in high(16∼32㎍/m㎖) venom concentration group but the beating frequency showed no definite correlation with the venom concentration. The above results suggested that Korean snake venom inhibited the influx of calcium ion across cell membrane to reduce the contractility like that in a ventricular muscle cell although the degree was slight.

특수교육 정보화 체제 구축 방안 연구

김종무,강경숙,강대식,Kim-Sung, Kellie K. 국립특수교육원 2001 연구보고서 Vol.- No.8

본 연구는 특수교육 정보화 관련 국내 · 외 문헌자료와 사례를 소개하고, 국내 특수교육정보화 실태 조사를 실시하여 첫째, 기초 통계자료를 확보하고 둘째, 효율적이면서도 실제적인 정보화체제 구축방안을 제시하는데 그 목적이 있다. 그동안 국내에서 광범위하게 추진되었던 교육정보화 사업에 있어서 전체 학교 학내망 설치와 같은 가시적인 정보화기반 구축 사업에 대해서는 전반적으로 성공적이라는 평가를하고 있지만 특정 수요 집단에게는 정보격차의 심화 및 접근성 문제의 심각성 등 부정적인 결과를 초래하기도 하였다. 이에 본 연구에서는 국내·외 특수교육 정보화 사례와 자료를 소개하고, 국내 특수교육정보화 실태를 파악하기 위한 설문조사를 실시하였다. 설문조사 대상은 특수학교 교사, 학생, 장애학생 부모, 장애인관련 단체 및 기관, 시 · 도교육청이었고, 조사 결과 특수학교 교사의 경우 컴퓨터 보유, 인터넷 사용 등에 있어서는 매우 양호하게 나타났으나 정보 활용기술에 해당하는 영역 즉, 장애학생을 교수하기 위한 자료의 제작과 교수-학습과정에서의 적용 수준에서는 저조하게 나타났다. 비장애학생과 비교할 수는 없지만 장애학생의 컴퓨터보유와 인터넷 사용 유 ·무에 관해서는 40~60%의 응답자가 긍정적으로 응답하였고 체계적인 지원이 수반된다면 좋은 결과가 있을 것으로 분석되었다. 본 연구에서는 정보화 지원 체제 구축 방안으로 크게 예산지원과 행정지원을 포함하여 특수학교, 교사, 학부모, 장애학생, 행정가, 장애인관련 기관 등의 요소로 구분하여 지원 방안을 제시하였다. 소개된 지원내용을 간략히 정리하면 다음과 같다. 첫째, 특수교육정보화 체제 구축을 위한 예산 지원은 외국의 사례에서도 나타났듯이 안정성과 지속성을 확보하기 위하여 '초·중등교육법', '특수교육진흥법'을 통해 지원에 관한 세부 사항을 법으로 규정해야한다. 둘째, 특수교육 정보화 사업과 관련된 부처간 행정 협조체제의 수립과 사업 중복성 등을 피하기 위하여 전담기구나 기관의 지정이 요구된다. 셋째, 특수학교의 경우, 학내망 설치와 더불어 장애인 접근성 문제의 해결을 위한 프로그램 개발과 하드웨어 장비의 지원, 교실간 네트워크 구축, 학교간 WAN 구축 등의 사업이 추진되어야 하며, 특수학급의 경우는 정보화 환경구축이 미흡하기 때문에 소속 교육청 과의 네트워크 구축을 통한 정보공유 및 행정업무의 연계가 필요하고, 다양한 교수-학습자료의 지원이 절실히 요구된다. 넷째, 특수교육 교사의 연수 기회를 확대하고 전문성을 키워줄 수 있는 연수내용과 방법의 개선이 필요하다. 장애학생 교육을 위한 학습자료 제작 기법, 장애인용 프로그램 사용법, 특수단말 장비 및 정보매체 활용 기법 등의 프로그램을 개발하여 집체+원격+화상 형태의 입체적인 연수가 요구된다. 다섯째, 장애학생 부모를 위한 정보화 지원은 학교-교육청간 협력하에 부모 교육 프로그램을 개발하여 우선, 학교와 인근 지역의 장애인관련 기관을 활용하여 정보소양 교육을 실시하고, 언제, 어디서나 교육이 가능한 원격이나 사이버시스템 등을 매개로 부모의 여건을 배려해줄 수 있는 편리한 교육방법이 준비되어야 한다. 여섯째, 교육청별 특수교육 담당장학사의 정보화 수준은 양호한 것으로 평가되지만 특수교육 정보화를 위한 특수학교(급) 교사의 연수지원을 위한 예산규모의 확보나 프로그램 개발 지원 등은 매우 부족한 것으로 나타났는데, 교육부(국립특수교육원)를 중심으로 전체 교육청의 특수교육 정보화 업무를 단일 체제로 묶는 인프라를 구축하여 예산, 프로그램, 네트워크 등을 공유토록 하여 효율성을 확보해야 한다. 일곱째, 장애인관련 단체는 정보화 업무 담당자를 배치하여 장애인과 일반인을 대상으로 활발한 정보화 교육이 이루어지고 있었지만 재정지원이 아직도 부족하고, 장애인용 프로그램과 기기의 보급이 부족하여 한계가 있는 것으로 드러났는데, 마찬가지로 장애인관련 기관을 하나로 묶는 인프라의 구축을 통해 사용되는 프로그램을 표준화시키고 예산지원의 중복성을 피해야하며 기관 이용자에 대한 관리의 편리성도 함께 도모해야 할 것이다. This study intends to collect baseline data and to present effective and practical methods of establishing special education IT system. An extensive review of both domestic and foreign literature and case studies of best practices were conducted for this research as well as the evaluation of the current state of technology usage and adoption in special education in Korea. Previous nationwide educational technology projects have accomplished notable and successful results such as building Intranet for schools. However, such efforts have, in away, created and aggravated the disproportionate gap, often called as the digital divide, against certain groups of people with unique needs. Also, the accessibility to such technology and information has emerged as a serious problem as the role of technology expanded. This study introduced both domestic and foreign examples of technology in special education and relevant resources, and conducted a large-scale survey to examine the current stage of technology adoption and usage in special education in Korea. The survey was administered to special education teachers, students, parents of students with disabilities, disability-related organizations and relevant agencies, and to municipal and provincial department of education. The results found satisfactory levels of computer ownership and usage of Internet among special education teachers. However, utilizing and incorporating such Information and technology into classroom activities and into teaching material development were still limited. Although the data were not comparable to those from students without disabilities, about 40 to 60 percent of the respondents showed positive attitudes toward computer ownership and Internet usage of students with disabilities, suggesting desirable outcomes with appropriate systematic support. Based on the findings, this study recommended detailed methods of building broad financial or budgetary assistance systems for special education schools, teachers, parents, students, administrators, and disability-related organizations. First, as shown in the experiences of foreign countries, financial support from the government to establish the system for the special education information technology has to be mandated under the 'Elementary and Secondary Education Act', the 'Special Education Promotion Act' to ensure and enhance stability and continuity. Second, designation of a single commanding and responsible agency is called for to efficiently coordinate inter-agency collaboration among governmental agencies and departments, and to avoid redundancy of work. Third, for special education schools, tasks such as building school-wide Intranet, development of software solving accessibility issues, subsidizing funds for computer hardware purchase, connecting classrooms through networking system and establishing inter-school WAN are of critical importance. Fourth, the contents and methods of professional development and training for special education teachers should be improved to professionalize teachers, and expansion of such opportunities are also called for. Fifth, IT support for parents of students with disabilities is also important. Parent education and training programs should be developed through active collaboration between local department of education and schools, and such training programs may be offered at schools or disability-related facilities. Distance learning or online courses, which the parents can access regardless of time or location, are other feasible alternatives. Sixth, the results found that administrative staffs of special education at each local department of education displayed satisfactory competence levels. However, the amount of budget assigned for special education teacher training or program development was seriously insufficient. Therefore, the Ministry of Education (or KISE) should build a universal infrastructure of IT, which encompasses and shares budget, program and network systems across all the IT offices of the local department of education. Seventh, although most disability organizations have IT specialist and offered IT education programs for both persons with and without disabilities, they have been experiencing continued problems of insufficient financial support and lack of adaptive technology devices and accessible programs. Therefore, building a universal infrastructure across disability organizations is called for to standardize programs, to prevent overlaps in funding, and thus, to enhance administrative efficiency.

좌심실 수축기 기능장애를 동반한 양수색전증 1예

박대균,홍경순,두영철,한규록,오동진,유규형,임종윤,고영박,이광학,이영,송원근,김현태 대한순환기학회 1999 Korean Circulation Journal Vol.29 No.8

Oxantel/Pyrantel 合劑 및 Mebendazole에 依한 腸內線蟲類 驅蟲效果에 對한 比較實驗

金鍾煥,辛大煥,林定圭 충남대학교 의과대학 지역사회의학연구소 1978 충남의대잡지 Vol.5 No.1

A total of 63 subjects with multiple intestinal nematode infection: T. trichiura, A. lumbricoides, E. vermicularis and T. orientalis were treated with Oxantel/Pyrantel suspension and Mebendazole. The administration of Oxantel/Pyrantel suspension was 15mg/kg body weight in a single dose and Mebendazole was 600mg, divided by 100mg, twice daily for three consecutive days regardless of the body weight or ages. The results of present trials are summarized as follows: 1. The egg negative conversion rates for Oxantel/Pyrantel suspension were 100% in 20 cases of Ascariasis and in 3 cases of T. orientalis infection, and 92.3% in 26 cases of Enterobiasis. The egg reduction rate of T. trichiura was 84.8%. 2. The Mebendazole treated group showed the egg negative conversion rates of 100% in 27 cases of Ascariasis and one case of Trichostrongyliasis, 88.5% in 26 cases of Enterobiasis and 19.4% is 32 cases of Trichuriasis. The egg reduction rate of T. trichiura was 89.4%. 3. With the Oxantel/Pyrantel treated group, adult worms were found T. trichiura 1449 (average 45.3), A. lumbricoides 81 (av. 4.1) and E. vermicularis 249 (av. 9.6) worms. In Mebendazole treated group demonstrated the number of adult worms: 406(av. 13.1) of T. trichiura, 79 (av. 2.9) of A. lumbricoides and 134 (av. 5.2) of E. vermicularis, respectively. 4. Side effects of both Oxantel/Pyrantel and Mebendazole were few and mild.

다발성 대장암 간전이 환자의 간절제를 위한 새로운 시도

주종우,김형철,임철완,신응진,조규석,유기원,송옥평,홍대식,박성진,조준희,이혜경,김희경,권계원,고은석 순천향의학연구소;Soonchunhyang Medical Research Institute 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

Multiple bilobar liver matastases (MBLM) are the main cause of low resectability in the colon cancer liver metastases. The authors experienced one case of initially non-resectable colon cancer liver metastases. He was curatively and safely treated with a two-stage hepatectomy using the new method of future remnant liver volume growing. A 54-year-old man was referred to our department with the sigmoid colon cancer combined with MBLM, which were checked in two small metastatic lesions in the left lobe and five large sized lesions in the right lobe in the computed tomogram (CT). A laparoscopic assisted anterior resection was primarily performed. We performed the 1^(st) stage hepatectomy 3 weeks after the colon resection. Intra-operative Ultrasonogram (US) found 9 small superficial metastatic lesions in the left lobe. All that lesions were completely removed by non-anatomical wedge resection. An occlusion ballon catheter was placed in the right portal vein through a small branch of the inferior mesenteric vein at that time. The future remnant liver volume was sufficiently increased 3 weeks after the 1^(st) hepatectomy. A right hepatectomy was safely performed 22 days after the 1^(st) hepatectomy. The patient received a regional chemotherapy (interleukin2 based immuno-chemotherapy through hepatic artery) for 4 months, then received 9 cycles of systemic chemotherapy (biweekly Oxaliplation, leucovorin, plus 5-fluorouracil) without any recurrence evidence.

大氣公害가 養蠶에 미치는 影響에 관한 硏究 : 人工 飼料中의 카드미움 濃度와 家蠶形質과의 關係 Relation between Silkworm larval characters and the levels of cadmium density in diets

李鍾哲,崔震浹,裵啓宣,孫興大,鄭元福 東亞大學校 大學院 1980 大學院論文集 Vol.4 No.2

Performed to study on effect of economic characters and quantity of Cd in silkworm body by feeding artificial diet which aded Cd per density to all age silkworms. The results were as follows: 1. Each treated parts was a little longer than control on silkworm larval duration. 2. Growing condition of 40 ppm on the 7th day after commencement incubation was uneven and found out around 80% of 1st instar-silkworm larvae which almost didn't grow at ones of 80 ppm. 3. Maximum weight of the 5th instar, pupation ratio, weight of cocoon, weight of cocoon layer and cocoon layer ratio of parts of 1,10, and 20 ppm was a lettle higher than control, but only ones of 40 ppm was lower than those. And found out it ws chronic toxicity. 4. Each treated parts on eclosion period was longer than control. Expecially non-eclosion ratio of 40 ppm was 30%. 5. The safe level density of Cd in diet was 20 ppm. 6. Toxicity will be occurred when Cd contents in is more than 5 PPM in silkworm body.