‘나혜석 거리’ 근대이미지 조성에 관한 연구

김정동,이기욱,조홍석,한수형,구명화 목원대학교 건축도시연구센터 2003 建築·都市環境硏究 Vol.11 No.-

As the first female artist of Western painting in the modern times, Hey-seok Na is the historical figure in Suwon, who went ahead of the times. Suwon City established the street of Hey-seok Na to commemorate her, in Ingye-dong, Paldal-gu. Street-establishment business for the historical figures is one of the factors with the biggest effects for the creation of local cultures. It has many merits such as the offer of fine view of city and resting area as well as giving the pride and educational effects to its residents. However, there are memorial hall or exhibitional hall not established in the street of Hey-seok Na, with the lacks in attractions and convenience facilities. With a poor decorative arrangement in the vicinity of the street, the meaning of street establishment and the image of Hey-seok Na are not well-delivered. Accordingly, the initial plan to make the street with citizens has not been well carried out. This research classified and analyzed the achievements and thoughts of Hey-seok Na, to embody it as the image and the concept of design to be expressed for the street was picked out. As a result, the image of Hey-seok Na, as the historical figure was set at modern times. the existing facilities in the street of Hey-seok Na was analyzed, centering on the time-factor of the modern times, deciding the spacial goal pursued by the street along with things to be improved.

高血壓 患者의 血壓管理實態와 韓方利用 現況

申宅秀,柳聖琦,鄭明秀,李起男 한국전통의학연구소 2006 한국전통의학지 Vol.15 No.1

This Study aims at looking into the use of oriental medical services in treating hypertension. The first objective to be explored through this study is the morbidity caused by the disease, classifying them by age, gender, and occupation. The second is to determine the regular use of anti-hypertensive medicine and their efficacy in controlling blood-pressure. The third is to investigate the use-rate and satisfaction of oriental medical service. 838 households across the country, were asked to answer questionnaires for the period of time from Apr. to Jun. 2005. The conclusion from the survey can be summarized as following. The age of which the first medical diagnosis of hypertension were made showed lower in males, those with higher education and income. The study showed females were more active in blood-pressure control, with their frequent monitoring of blood-pressure for the past year. With age, people in under 50 age group proved to be less active. The management of high blood pressure was more effective in group with regular dosage compared to group with irregular use of anti-hypertensive medication, but their difference was minimal. Also, group with no medication showed signs of blood-pressure control. The use of oriental medical service for the past year, were more frequent in groups with lower education, either low or high income, old age, females and occupations in agriculture, forestry and fishing industry. Results were similar in both general population and high blood-pressure patient group. Females, people over 51 years old and with lower education showed more intentions in utilizing oriental medical services in the future. Results were similar in both general population and high blood-pressure patient group. It is necessary to offer a more accurate information on oriental medical treatments. Also, a systematic reform to reduce the patient's share of the treatment cost, as well as, heightening public awareness on the infirmity of present blood-pressure management system is crucial.

Streptozotocin 유발 당뇨 쥐의 혈당 및 혈청 지질에 미치는 한방추출물의 효과와 최적 농도에 관한 연구

정명수(Myong-Soo Chong),김혜자(Hae-Ja Kim),조화은(Hwa-Eun Cho),최윤희(Yun-Hee Choi),이기남(Kin-Am Lee) 대한한의학회 2008 대한한의학회지 Vol.29 No.1

Poria cocos ethanol extract and its active constituent, pachymic acid, modulate sleep architectures via activation of GABAA-ergic transmission in rats

Vikash Kumar Shah,Sam-Shik Na,Myong-Soo Chong,Jae-Hoon Woo,Yeong-Ok Kwon,Mi Kyeong Lee,Ki-Wan Oh 충북대학교 동물의학연구소 2015 Journal of Biomedical and Translational Research Vol.16 No.3

Poria cocos is a well-known traditional Chinese traditional medicine (TCM) that grows around roots of pine trees in China, Korea, Japan, and North America. Poria cocos has been used in Asian countries to treat insomnia as either a single herb or part of an herbal formula. In a previous experiment, pachymic acid (PA), an active constituent of Poria cocos ethanol extract (PCE), increased pentobarbital-induced sleeping behaviors. The aim of this experiment was to evaluate whether or not PCE and PA modulate sleep architectures in rats as well as whether or not their effects are mediated through GABAA-ergic transmission. PCE and PA were orally administered to individual rats 7 days after surgical implantation of a transmitter, and sleep architectures were recorded by Telemetric Cortical encephalogram (EEG) upon oral administration of test drugs. PCE and PA increased total sleep time and non-rapid eye movement (NREM) sleep as well as reduced numbers of sleep/wake cycles recorded by EEG. Furthermore, PCE increased intracellular chloride levels, GAD65/67 protein levels, and α-, β-, and γ-subunits of GABAA receptors in primary cultured hypothalamic neuronal cells. These data suggest that PCE modulates sleep architectures via activation of GABAA-ergic systems. Further, as PA is an active component of PCE, they may have the same pharmacological effects.

Survival outcomes after extensive cytoreductive surgery and selective neoadjuvant chemotherapy according to institutional criteria in bulky stage IIIC and IV epithelial ovarian cancer

Lim, Myong Cheol,Yoo, Heong Jong,Song, Yong Jung,Seo, Sang-Soo,Kang, Sokbom,Kim, Sun Ho,Yoo, Chong Woo,Park, Sang-Yoon Asian Society of Gynecologic Oncology; Korean Soci 2017 Journal of Gynecologic Oncology Vol.28 No.4

<P><B>Objective</B></P><P>To investigate the survival outcomes in patients with bulky stage IIIC and IV ovarian cancer, treated by primary debulking surgery (PDS) and selective use of neoadjuvant chemotherapy (NAC) according to institutional criteria.</P><P><B>Methods</B></P><P>Medical records for advanced ovarian cancer patients who were treated at National Cancer Center (NCC) between December 2000 and March 2009 were retrospectively reviewed in the comprehensive cancer center. Bulky stage IIIC and IV ovarian cancer cases were included. Current NCC indication for NAC is determined based on patients' performance status and/or computerized tomography (CT) findings indicating difficult cytoreduction. After NAC, all traces of regressed metastatic ovarian cancer, potentially including chemotherapy-resistant cancer cells, were surgically removed.</P><P><B>Results</B></P><P>Of the 279 patients with bulky stage IIIC and IV, 143 (51%) underwent PDS and 136 (49%) received NAC. No gross residual and residual tumor measuring ≤1 cm was achieved in 66% and 96% of the PDS group and 79% and 96% of the NAC group, respectively. The median progression-free survival (PFS) and overall survival (OS) time were 20 months and not reached, but might be estimated more than 70 months in the PDS group and 15 and 70 months in the NAC group, respectively.</P><P><B>Conclusion</B></P><P>Extensive cytoreductive surgery to minimize residual tumor and selective use of NAC based on the institutional criteria could result in improved survival outcomes. Until further studies can be done to define the selection criteria for NAC after surgery, institutional criteria for NAC should consider the ability of the surgeon and institutional capacity.</P>

어려운 기도를 가진 환자에서 Airwayscope, 직접 후두경, 광봉을 이용한 기관내 삽관에 따른 심혈관계 반응의 비교

전명숙 ( Myong Sook Jeon ),김종수 ( Chong Soo Kim ),허진 ( Jin Huh ),민성원 ( Seong Won Min ),노영진 ( Young Jin Ro ),김대욱 ( Dae Wook Kim ),김덕경 ( Duk Kyung Kim ) 대한마취과학회 2009 Korean Journal of Anesthesiology Vol.57 No.3

Background: Airwayscope (AWS), which has been used successfully for difficult airway in general anesthesia, has been anticipated that hemodynamic response to tracheal intubation in the difficult airway may be attenuated. Also, there is a series of reports demonstrating the successful use of lightwand to open the difficult airway. Thus, we decided to conduct a survey to compare AWS to lightwand and to direct laryngoscopy of cardiovascular response to tracheal intubation. Methods: Of 64 healthy patients without cardiovascular disease, 22, 21, 21 patients were randomly assigned to AWS group, lightwand group and direct laryngoscope group. After induction of general anesthesia, intubation was performed with manual in-line neck stabilization. During laryngoscopy, a modified Cormack-Lehane grade was assessed and time to intubation was measured. Systolic arterial pressure (SAP) and heart rate (HR) were recorded at the following timepoints: baseline, just before intubation, 1 min, 2 min, 3 min, 4 min and 5 min after intubation. Results: There were no significant differences between the 3 groups in SAP, HR (P>0.05). However modified Cormack-Lehane grade of all patients in the AWS group was I, while that in direct laryngoscope group was IIB or III. In addition, the mean time to intubation of the direct laryngoscope group was significantly longer than that of the AWS and lightwand (P<0.05). Conclusions: In the difficult airway, AWS was very effective in improving laryngeal view and decreasing time to intubation compared to direct laryngoscopey. In addition, lightwand reduced the time to intubation. However we could not find any significant difference in hemodynamic response to tracheal intubation among the 3 groups. (Korean J Anesthesiol 2009;57:284∼9)

신생아 피하지방괴사

차명훈(Myong Hun Cha),김종민(Jong Min Kim),이종주(Chong Ju Lee),이일수(Eil Soo Lee) 대한피부과학회 1983 대한피부과학회지 Vol.21 No.3

Subcutaneous fat necrosis of the newborn is an uncommon disorder which is characterized by multiple erythematous subcutaneous nodules and plaques appearing in the first week to a month of life. The chief precipitating factors presumably concerned in this disease are obstetric trauma, anoxia and cold exposure. We observed a case of subcutaneous fat necrosis of the newborn in which intrauterine asphyxia and preeclampsia had occured.

Reserpine이 家兎卵巢와 子宮 및 腦組織의 水分 및 電解質에 미치는 影響

李明秀,李壽鍾 고려대학교 의과대학 1974 고려대 의대 잡지 Vol.11 No.1

Reserpine, one of the rouwolfian alkaloid has been used as hyptoensive and diuretics not only for toxemia of pregnancy but also for other conditions in the obstetrical and gynecological field. Althogh reserpine decreases blood pressure, it has a number of untoward side effects such as inhibition of gooadal stimulation, and lso responds to hypothalamus and pituitary adrenal axis. Author has attempted to clarify the effects of reserpine on water and electrolytes in the tissue of the uterus and cerebral cortex of mature female rabbits weighing around 2.0kg. A group of rabbits preconditioned with 50 I. U. /kg of HCG and another group with 1.5mg/kg of reserpine plus 50 I.U./kg HCG were observed 24 hours after conditioning. The results obtained were as follows: 1. The HCG preconditioned mature female rabbits showed acceleration in maturation of the follicles and ovulation in the ovaries but in the reserpine plus HCG preconditioned group showed corpus luteum. 2. Changes in electrolyte levels in serum of the HCG preconditioned rabbits showed an increase in sodium, potassium and calcium levels and a decrease in chloride and magnesium levels. The level of inagnesium in the reserpine plus HGG preconditioned group showed remarkable decreaaed. 3. Water and calcium of the uterine tissue in the HCG preconditioned mature female rabbits showed increase in contents compared to the normal group and a decrease in chloride, sodium and magnesium. In the reserpine plus HCG preconditioned group chloride and potassium, magnesium were remarkable decreased in each level. HCG administration showed no supression in electorlytes in uterine tissue. 4. Contents of water and electrolytes in cerebral cortex of mature female rabbits of HCG preconditioned group showed an increase chloride, sodium and potassium levels .and a decrease in water and magnesium levels. 5. Water content of the cerebral cortex of normal mature female rabbits produced no appreciable change than that of the uterine tissue. The reserpine plus HCG preconditioned group showed water content in the uterus was higher than that of the cerebra1 cortex. 6. Chloride content of the uterine tissue in normal showed higher than that of cerebral cortex and HCG preconditioned group showed no siginificant difference in chloride content. The reserpine plus HCG, preconditioned group, chloride content of cerebral cortex showed higher than that of the uterine tissue. 7. Sodium content of the uterine tissue in normal and HCG preconditioned one showed higher level than that of the cerebral cortex, the reserpine plus HCG preconditioned group were higher than those of the cerebral cortex. 8. The level of potassium of the uterine tissue in normal, HCG preconditioned and the reserpine plus HCG precitioned group were higher than those of the cereral corex. 9. The level of calcium of the uterine tissue and cerebral cortex in normal were same level. The level of calcium of the uterine tissue in HCG preconditioned and the reserpine plus HCG preconditioned group were higher than that of the cerebral cortex. 10. The level of content of magnesium of the uterine tissue in normal, HCG preconditioned and the reserpine olus HCG preconditioned group showed no change compared to the magnesium of the cerebral cortex.

Comparison of the Abbott RealTime High Risk HPV test and the Roche cobas 4800 HPV test using urine samples

Lim, Myong Cheol,Lee, Do-Hoon,Hwang, Sang-Hyun,Hwang, Na Rae,Lee, Bomyee,Shin, Hye Young,Jun, Jae Kwan,Yoo, Chong Woo,Lee, Dong Ock,Seo, Sang-Soo,Park, Sang-Yoon,Joo, Jungnam Elsevier 2017 JOURNAL OF VIROLOGICAL METHODS Vol.243 No.-

<P><B>Abstract</B></P> <P><B>Background</B></P> <P>Human papillomavirus (HPV) testing based on cervical samples is important for use in cervical cancer screening. However, cervical sampling is invasive. Therefore, non-invasive methods for detecting HPV, such as urine samples, are needed.</P> <P><B>Objectives</B></P> <P>For HPV detection in urine samples, two real-time PCR (RQ-PCR) tests, Roche cobas 4800 test (Roche_HPV; Roche Molecular Diagnostics) and Abbott RealTime High Risk HPV test (Abbott_HPV; Abbott Laboratories) were compared to standard cervical samples.</P> <P><B>Study design</B></P> <P>The performance of Roche_HPV and Abbott_HPV for HPV detection was evaluated at the National Cancer Center using 100 paired cervical and urine samples. The tests were also compared using urine samples stored at various temperatures and for a range of durations.</P> <P><B>Results</B></P> <P>The overall agreement between the Roche_HPV and Abbott_HPV tests using urine samples for any hrHPV type was substantial (86.0% with a kappa value of 0.7173), and that for HPV 16/18 was nearly perfect (99.0% with a kappa value of 0.9668). The relative sensitivities (based on cervical samples) for HPV 16/18 detection using Roche_HPV and Abbott_HPV with urine samples were 79.2% (95% CI; 57.9–92.9%) and 81.8% (95% CI; 59.7–94.8%), respectively. When the cut-off C<SUB>T</SUB> value for Abbott_HPV was extended to 40 for urine samples, the relative sensitivity of Abbott_HPV increased to 91.7% from 81.8% for HPV16/18 detection and to 87.0% from 68.5% for other hrHPV detection. The specificity was not affected by the change in the C<SUB>T</SUB> threshold.</P> <P><B>Conclusions</B></P> <P>Roche_HPV and Abbott_HPV showed high concordance. However, HPV DNA detection using urine samples was inferior to HPV DNA detection using cervical samples. Interestingly, when the cut-off C<SUB>T</SUB> value was set to 40, Abbott_HPV using urine samples showed high sensitivity and specificity, comparable to those obtained using cervical samples. Fully automated DNA extraction and detection systems, such as Roche_HPV and Abbott_HPV, could reduce the variability in HPV detection and accelerate the standardization of HPV detection in urine. Thus, urine samples may be an effective alternative for HPV detection in women who hesitate to participate in cervical cancer screening programs.</P> <P><B>Highlights</B></P> <P> <UL> <LI> The purpose of this study was to evaluate urine as a source of HPV detection. </LI> <LI> Two real-time PCR for HPV detection in urine showed high agreement. </LI> <LI> However, detection of HPV DNA using urine samples was inferior to HPV DNA detection using cervical samples. </LI> <LI> When the cut-off C<SUB>T</SUB> of Abbott RealTime High Risk HPV was adjusted to 40, urine samples were comparable to cervical samples. </LI> </UL> </P>

Region-based diagnostic performance of multi-detector CT for detecting peritoneal seeding in ovarian cancer patients(초)

임명철 ( Myong Cheol Lim ),( Hyuck Jae Choi ),( Dae Chul Jung ),( Sokbom Kang ),( Chong Woo Yoo ),( Sang Soo Seo ),( Sang Yoon Park ) 대한산부인과학회 2009 대한산부인과학회 학술대회 Vol.95 No.-