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‘Z-trip’? A Comprehensive Overview and a Case-series of Zolpidem Misuse
Laura Orsolini,Stefania Chiappini,Paolo Grandinetti,Angelo Bruschi,Roberta Testa,Alessandra Provenzano,Domenico De Berardis,Umberto Volpe 대한정신약물학회 2021 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.19 No.2
Although believed safer compared to short-acting benzodiazepines (BZD), in the past few years a growing concern has developed relating to the abuse of Z-drugs, and specifically of zolpidem. Here we aim to review the evidence for the misuse of zolpidem and describe several related cases collected in Italy. A comprehensive overview is here carried by using several databases, and by combining the search strategy of free text terms and exploding a range of MESH headings relating to the topics of Zolpidem and Abuse and/or Misuse as follows: ((Zolpidem [Title/Abstract]) AND (Abuse[Title/Abstract]) OR (Misuse[Title/Abstract])), without time and/or language restrictions. Furthermore, a case series of 8 cases of zolpidem misuse and/or abuse, collected in different Italian psychiatric settings (psychiatric public hospital, psychiatric private rehabilitation clinic, and private practice), have been here described. According to our findings, zolpidem should be prescribed with the same caution as BZDs, especially in patients with a history of drug abuse or in the elderly. Behavioural modifications, including bizarre behaviours, psychomotor agitation, sleep-related complex behaviours have been reported. Monitoring of zolpidem use in selected populations is warranted. Psychiatrists and physicians should be aware of the misuse potential of zolpidem and adopt measures restricting its use.
Modeling Meridians Within the Quantum Field Theory
Larissa Brizhik,Enrico Chiappini,Patrizia Stefanini,Giuseppe Vitiello 사단법인약침학회 2019 Journal of Acupuncture & Meridian Studies Vol.12 No.1
We present here a model of meridians in the formalism of the gauge theory paradigm of quantum field theory with spontaneous breakdown of symmetry. We discuss the origin and dynamic self-focusing propagation of the electromagnetic field in coherent states and the role it plays in our meridian modeling. Within this frame, we consider the formation of solitary waves on proteins and anatomical filamentary structures and discuss nondissipative energy transport. Finally, we analyze the relation of meridians with anatomical filamentary structures, the reciprocal actions between meridians, and biochemical activity and the key role played by free energy, internal energy, and entropy.
Spectro-photometric distances to stars: A general purpose Bayesian approach
Santiago, Basí,lio X.,Brauer, Dorothé,e E.,Anders, Friedrich,Chiappini, Cristina,Queiroz, Anna B.,Girardi, Lé,o,Rocha-Pinto, Helio J.,Balbinot, Eduardo,da Costa, Luiz N.,Maia, Marcio EDP Sciences 2016 Astronomy and astrophysics Vol.585 No.-