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배치혜(Chihye Bae),이현정(Hyeonjeong Lee),전정윤(Chungyoon Chun) 한국태양에너지학회 2009 한국태양에너지학회 학술대회논문집 Vol.2009 No.11월
The purpose of this study is to develop of portable thermal comfort measurement tool for elderly. Using prediction expression of thermal comfort for elderly which derived at previous study, a field studies were conducted. The objects of this survey are old persons over 60 years old and total 296 (male:111 persons, female:145 persons) persons were measured. The actual thermal sensation was compared with predicted thermal sensation calculated with PMV model, and the results shows that there were no correlation between them. Also, appling cheek temperature and hand temperature were useful to predict thermal sensation of elderly people. Especially, predicted thermal sensation using cheek temperature were closely connected with actual thermal sensation of elderly and presented most similar trend to actual thermal sensation.
Exposure to Stressors Facilitates Long-Term Synaptic Potentiation in the Lateral Habenula
Park, Hoyong,Rhee, Jeehae,Park, Kwanghoon,Han, Jung-Soo,Malinow, Roberto,Chung, ChiHye Society for Neuroscience 2017 The Journal of neuroscience Vol.37 No.25
<P>The lateral habenula (LHb) is a small part of the epithalamus that projects to monoamine centers in the brain. Previously, neurotrans-mission onto the LHb was shown to be abnormally potentiated in animal models of depression. However, synaptic plasticity in this brain area and the effect of stressor exposure on synaptic plasticity of the LHb have not been investigated. Thus, we explored whether the LHb undergoes dynamic changes in synaptic efficacy or not. First, we observed that a moderate LTP occurs in a fraction of LHb neurons obtained from naive Sprague Dawley rats. Interestingly, a single exposure to acute stressors, such as inescapable foot shock or restraint plus tail shock (RTS), significantly enhances the magnitude of LTP in the LHb. We also observed an increased number of LHb neurons expressing phosphorylated cAMP response element-binding protein (pCREB) after exposure to stressors, which may contribute to determine the threshold for LTP induction. LTP induction in the LHb resulted in an additional increase in the number of pCREB expressing neurons in stress-exposed animals but not in naive control animals. Together, we showed that LHb neurons have heterogeneous propensity for synaptic potentiation at rest; however, a single exposure to stressors greatly facilitates LTP induction in the LHb, suggesting that fundamental alterations in synaptic plasticity in the LHb may occur in animal models of depression or post-traumatic stress disorder.</P>