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      • 악하선 암의 치료성적과 예후인자

        임치영(Chi Young Lim),남기현(Kee Hyun Nam),이잔디(Jan Dee Lee),장항석(Hang Seok Chang),정웅윤(Woong Youn Chung),차인호(In Ho Cha),이창걸(Chang Geol Lee),최은창(Eun Chan Choi),박정수(Cheong Soo Park) 대한두경부종양학회 2005 대한두경부 종양학회지 Vol.21 No.2

        Purpose: Submandibular gland tumor is rare, less than 6% of head and neck tumor. The purpose of this article is to analysis the clinical experience and treatment outcomes of malignant submandibular gland tumor, suggesting a guideline of management. Methods: We retrospectively evaluated 26 patients who underwent operation for malignant submandibular gland tumor at Severence hospital between 1986 and 2004. Statistical analysis was performed by Kaplan-Meier method, log rank test, Chi-square test, Fisher's exact test using SPSS v12.0 for Windows. Results: They consisted of 18 males and 8 females whose median age was 47 years(range: 20-71). 10 cases of adenocystic carcinoma, 8 cases of carcinoma ex pleomorphic adenoma, 4 cases of mucoepidermoid carcinoma, 1 case each for acinic cell carcinoma, undifferentiated carcinoma, adeno carcinoma, epithelioid hemangioendothelioma. Sialoadenectomy only was performed in 10 cases(36.5%) and sialoadenectomy with neck node dissection was performed in 16 cases(63.5%). Adjuvant radiotherapy was done in 22 cases(84.6%). 10 year disease free survival rate for malignant submandibular gland tumor was 63.1 % and 10 year overall survival rate for malignant submandibular gland tumor was 70.1%. In univariate analysis, prognostic factors affecting recurrence of malignant submandibular gland tumor was initially papable lateral neck node in physical examination and metastasis of lateral neck node in pathologic confirmation. The prognostic factors affecting survival of malignant submandibular gland tumor was tumor size, TNM stage, recurrence and type of recurrence. Conclusion: In this study, prognostic factors affecting recurrence of malignant submandibular gland tumor was initially papable lateral neck node in physical examination and metastasis of lateral neck node in pathologic confirmation. The prognostic factors affecting survival of malignant submandibular gland tumor was tumor size, TNM stage, recurrence and type of recurrence. To prevent recurrence and to improve survival, early diagnosis and aggressive surgery must be considered.

      • Prevalence of Musculoskeletal Symptoms in Taiwan's Traditional Industries

        Yu, Chi-Yuang,Hsu, Yau-Wen,Chung, Yi-Chan,Tsai, Chih-Hung The Korean Society for Quality Management 2004 The Asian Journal on Quality Vol.5 No.2

        The purpose of this study was to analyze the prevalence of self-reported musculoskeletal symptoms among the three Taiwan's traditional industries as lathe, electronics and food by the Nordic Musculoskeletal Questionnaire (NMQ). Moreover, the study was also to make a comparison among the aforesaid industries for revealing their differences. The result of the questionnaire indicated that the symptoms appeared on the three industries were all originated from four parts as neck, shoulders, elbows, and wrists/hands. More than 68% of the interviewers thought that their symptoms might be related to their work. However, the rate of harmful influence resulted from life or job was over 50%. As to the respect of the interviewers' attitude in treating their symptoms, more than 80% of them neglected or just treated the symptoms by massaging or cold/hot compressing and resting. From the questionnaire, the proportion of symptoms discussed in each item indicated that the distribution, in perceiving symptom, of interviewers were not quite identical; however the Chi-square test discovered majority did not reach 0.05 levels, hence the difference among industries were not significant.

      • KCI등재

        Extended use of Prostate Health Index and percentage of [-2]pro-prostate-specific antigen in Chinese men with prostate specific antigen 10–20 ng/mL and normal digital rectal examination

        Peter Ka-Fung Chiu,Jeremy Yuen-Chun Teoh,Wai-Man Lee,Chi-Hang Yee,Eddie Shu-Yin Chan,See-Ming Hou,Chi-Fai Ng 대한비뇨의학회 2016 Investigative and Clinical Urology Vol.57 No.5

        Purpose: We investigated the extended use of Prostate Health Index (PHI) and percentage of [-2]pro-prostate-specific antigen (%p2PSA) in Chinese men with prostate-specific antigen (PSA) 10–20 ng/mL and normal digital rectal examination (DRE). Materials and Methods: All consecutive Chinese men with PSA 10–20 ng/mL and normal DRE who agreed for transrectal ultrasound (TRUS)-guided 10-core prostate biopsy were recruited. Blood samples were taken immediately before TRUS-guided prostate biopsy. The performances of total PSA (tPSA), %free-to-total PSA (%fPSA), %p2PSA, and PHI were compared using logistic regression, receiver operating characteristic, and decision curve analyses (DCA). Results: From 2008 to 2015, 312 consecutive Chinese men were included. Among them, 53 out of 312 (17.0%) men were diagnosed to have prostate cancer on biopsy. The proportions of men with positive biopsies were 6.7% in PHI<35, 22.8% in PHI 35–55, and 54.5% in PHI>55 (chi-square test, p<0.001). The area under curves (AUC) of the base model including age, tPSA and status of initial/repeated biopsy was 0.64. Adding %p2PSA and PHI to the base model improved the AUC to 0.79 (p<0.001) and 0.78 (p<0.001), respectively, and provided net clinical benefit in DCA. The positive biopsy rates of Gleason 7 or above prostate cancers were 2.2% for PHI<35, 7.9% for PHI 35–55, and 36.4% for PHI>55 (chi-square test, p<0.001). By utilizing the PHI cutoff of 35 to men with PSA 10–20 ng/mL and normal DRE, 57.1% (178 of 312) biopsies could be avoided. Conclusions: Both PHI and %p2PSA performed well in predicting prostate cancer and high grade prostate cancer. The use of PHI and %p2PSA should be extended to Chinese men with PSA 10–20 ng/mL and normal DRE.

      • An experimental investigation of the cyclic response of bucket foundations in soft clay under one-way cyclic horizontal loads

        Hung, Le Chi,Lee, Si-Hoon,Vicent, Ssenyondo,Kim, Sung-Ryul Elsevier 2018 Applied ocean research Vol.71 No.-

        <P><B>Abstract</B></P> <P>This study conducted 1 <I>g</I> laboratory tests to investigate the accumulated rotation and unloading stiffness of two model bucket foundations embedded in soft clay under one-way cyclic horizontal loads. The model bucket foundations were specifically designed to have embedment ratios of 0.5 and 1. Ground models were prepared by consolidating the kaolin slurry. One-way cyclic horizontal loads of up to 10<SUP>4</SUP> cycles were applied varying loading magnitudes. Test results showed that the accumulated rotations of the bucket foundations increased with increased number of load cycles and cyclic horizontal load magnitudes. The unloading stiffness of the bucket foundations increased with increasing number of cycles and embedment ratios but decreased with increasing cyclic horizontal load magnitude. Based on the model test results, empirical equations were proposed to evaluate the accumulated rotation and unloading stiffness of the bucket foundations in soft clay under one-way cyclic horizontal loads.</P>

      • Experimental investigation of the vertical pullout cyclic response of bucket foundations in sand

        Hung, Le Chi,Lee, Sihoon,Tran, Nghiem Xuan,Kim, Sung-Ryul Elsevier 2017 Applied ocean research Vol.68 No.-

        <P><B>Abstract</B></P> <P>A series of 1g model tests was conducted to investigate the accumulated vertical pullout displacement and unloading stiffness of bucket foundations embedded in dry and saturated sands. The foundations were subjected to vertical pullout cyclic loading with different load amplitudes. Cyclic load was applied up to 10<SUP>4</SUP> cycles. Test results showed that the accumulated vertical pullout displacement increased with the increase in the number of load cycles and cyclic load amplitudes. The unloading stiffness of the bucket foundations decreased with the increase in load amplitude and number of cycles. Empirical equations were proposed based on the test results to evaluate the accumulated vertical pullout displacement and unloading stiffness of the bucket foundations in saturated sand. These equations can be used for the preliminary design of single or tripod bucket foundations.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Cyclic response of bucket foundations in saturated sand under cyclic vertical pullout load was examined by 1 <I>g</I> model tests. </LI> <LI> Accumulated displacement increased with the increase in number of load cycles and load magnitude. </LI> <LI> Unloading stiffness decreased with the increase in number of load cycles and load magnitude. </LI> <LI> Empirical equations have been proposed. </LI> </UL> </P>

      • KCI등재

        The Risk of Upper Urinary Tract Involvement in Patients With Ketamine-Associated Uropathy

        Chi-Hang Yee,Jeremy Yuen-Chun Teoh,Pui-Tak Lai,Vivian Yee-Fong Leung,Winnie Chiu-Wing Chu,Wai-man Lee,Yuk-Him Tam,Chi-Fai Ng 대한배뇨장애요실금학회 2017 International Neurourology Journal Vol.21 No.2

        Purpose: The aims of this study were to investigate the prevalence of upper tract involvement in ketamine-associated uropathy, and to determine the predictors of hydronephrosis in patients with a history of ketamine abuse. Methods: This was a cross-sectional study of a prospective cohort of patients with ketamine-associated uropathy. Data including demographics, pattern of ketamine abuse, pelvic pain and urgency or frequency (PUF) symptom score, uroflowmetry (UFM) parameters, serum renal function, and liver function tests were collected. Upon consultation, ultrasonography was performed to assess the function of the urinary system. Results: From December 2011 to October 2015, we treated 572 patients with ketamine-associated uropathy. Of these patients, 207 (36.2%) had managed to achieve abstinence at the time of their first consultation. Ninety-six patients (16.8%) in the cohort were found to have hydronephrosis on ultrasonography. Univariate analysis identified age, duration of ketamine abuse, PUF symptom score, voided volume on UFM, serum creatinine levels >100 μmol/L, and an abnormal serum liver enzyme profile as factors associated with hydronephrosis. Logistic regression revealed the following parameters to be statistically related to hydronephrosis: age (adjusted odds ratio [OR], 1.090; 95% confidence interval [CI], 1.020–1.166; P=0.012), functional bladder capacity (adjusted OR, 0.997; 95% CI, 0.995–0.999; P=0.029), serum creatinine >100 μmol/L (adjusted OR, 3.107; 95% CI, 1.238–7.794; P=0.016, and an abnormal serum liver enzyme profile (adjusted OR, 1.967; 95% CI, 1.213–3.187; P=0.006). Conclusions: Ketamine-associated uropathy can involve the upper urinary tract. Patient demographics as well as investigations of UFM, renal function tests, and liver function tests may allow us to identify at-risk patients.

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