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김지연 ( Chi Yeon Kim ),김경태 ( Kyeong Tae Kim ),오지원 ( Chee Won Oh ) 대한피부과학회 2006 대한피부과학회지 Vol.44 No.11
Supernummerary breast is a rare developmental anomaly occurring along the course of the embryological milk lines, which run from the anterior axillary folds to the inner thighs. Kajava first described the classification of supernumerary tissue in 1915, and this term is still in use. We herein report two cases of supernumerary breast, classified as Kajava classification type 3 and 6. (Korean J Dermatol 2006;44(11):1360~1363)
김지연 ( Chi Yeon Kim ),박상영 ( Sang Young Park ),안성기 ( Seong Ki Ahn ),오지원 ( Chee Won Oh ) 대한피부과학회 2007 대한피부과학회지 Vol.45 No.4
Melanoacanthoma, a rare benign variant of seborrheic keratosis, was first introduced by Mishima and Pinkus in 1960. It is a slow-growing, painless, pigmented plaque with a verrucous surface and a diameter ranging from a few millimeters to 10 cm. It tends to develop during middle-age with an equal sex incidence, and the lesion usually presents on the head, trunk, and especially the lip. It also has a histopathologic finding of mixed neoplasm composed of melanocytes scattered throughout keratinocytic lobules, and is characterized by hyperkeratosis, parakeratosis, acanthosis, papillomatosis and pseudo-horn cysts in the epidermis. We report a case of melanoacanthoma occurring in a 52-year-old female, who presented with an easily bleeding mass on her right external auditory canal, an extremely uncommon site. (Korean J Dermatol 2007;45(4):369~372)
김지연 ( Chi Yeon Kim ),윤지미 ( Ji Mi Yoon ),오지원 ( Chee Won Oh ) 대한피부과학회 2010 대한피부과학회지 Vol.48 No.10
Nevus comedonicus is an uncommon skin disorder that clinically appears as linear groups of open comedones. A 6-year-old female patient presented with a nevus comedonicus accompanied by an epidermal nevus in her genital area. The histopathologic finding showed an atrophic, cystically dilated hair follicle containing abundant keratinous debris. She was treated with oral antibiotics. We report here on an unusual case of nevus comedonicus that occurred in the genital area. (Korean J Dermatol 2010;48(10):880~883)
클론증형 지루 각화증과 표피내 에크린 땀구멍종 분화를 보인 표피내 상피종
김지연 ( Chi Yeon Kim ),이승훈 ( Seung Hun Lee ),오지원 ( Chee Won Oh ) 대한피부과학회 2009 대한피부과학회지 Vol.47 No.9
Intra-epidermal epithelioma is a rare cutaneous neoplasm and generally used as a histologic description for superficial tumors in which nests are found in well-defined islands within the epidermis. The intra-epidermal nests are composed of keratinocytes, and basaloid or squamoid or pleomorphic cells. Some authors reported that this tumor may be considered an invasion of the epidermis from a malignant tumor and it has the potential of carcinomatous invasion. Herein, we report a case of intra-epidermal epithelioma that showed clonal seborrheic keratosis and intra-epidermal eccrine poroma differentiation on the right thigh areaof a 77-year-old female. Although intra-epidermal epithelioma shows benign features, it may be predisposed to other tumoral changes, such as eccrine poroma, eccrine porocarcinoma, and Bowen`s disease. We suggest that individuals with intra-epidermal epithelioma require continuous monitoring of skin changes, including enlargement of size, inflammation, ulceration, and hemorrhages. (Korean J Dermatol 2009;47(9):1043∼1047)
김지연 ( Chi Yeon Kim ),박상영 ( Sang Young Park ),오지원 ( Chee Won Oh ) 대한피부과학회 2008 대한피부과학회지 Vol.46 No.3
Lichen spinulosus is an uncommon idiopathic disorder characterized by scattered 2 cm to 6 cm patches of keratotic follicular papules. Individual papules are 1 to 3 mm in diameter and consist of a hairlike horny spine. Lesions are typically skin colored and asymptomatic or mildly pruritic. It occurs mainly in children and adolescents. Although several factors, such as atopy, infection, drug reaction, id reaction to fungal infection, and heredity, have been proposed as playing a role in lichen spinulosus, most cases are not associated with any systemic abnormalities. Lichen spinulosus is usually a symmetrical lesion that occurs on the trunk or extremities. Herein, we report a case of lichen spinulosus in a 7-year-old child in the submental area, an uncommon site. (Korean J Dermatol 2008; 46(3):378∼380)
김지연(Chi Yeon Kim),김태흥(Tae Heung Kim),윤태진(Tae Jin Yoon) 대한피부과학회 2001 대한피부과학회지 Vol.39 No.10
Dyskeratosis congenita is a rare inherited multisystemic condition involving mainly the ectoderm. Clinically it is characterized by a triad of reticular skin pigmentation, nail dystrophy and leukoplakia of mucous membranes. Complications are predisposition to malignancy and bone marrow involvement with pancytopenia. Dyskeratosis congenita occurs predominantly in male by a male to female ratio of 13:1. The mode of inheritance is uncertain. Several studies support X-linked recessive transmission, but its occurrence in females suggests genetic heterogeneity. We report a rare case of dyskeratosis congenital in a woman. (Korean J Dermatol 2001;39(10): 1162~1165)
김지연 ( Chi Yeon Kim ),오지원 ( Chee Won Oh ) 대한피부과학회 2008 대한피부과학회지 Vol.46 No.11
Progressive facial hemiatrophy (PFH) was first described by Parry and Romberg and this is a rare disorder of an unknown origin. PFH is characterized by slowly progressive, mostly unilateral facial atrophy of the skin, soft tissues, muscles and underlying bony structures and is usually develops in the first or second decade of life. Although the clinical presentation of PFH may appear similar to localized linear scleroderma en coup the sabre, some patients presenting with PFH have neither en coup the sabre nor generalized sclerosis. Herein, we report on an unusual case of a 7-year-old girl who presented with progressive hemiatrophy of the face. (Korean J Dermatol 2008; 46(11): 1538∼1542)
김지연 ( Chi Yeon Kim ),윤태진 ( Tae Jin Yoon ),김태흥 ( Tae Heung Kim ),오지원 ( Chee Won Oh ) 대한피부과학회 2001 대한피부과학회지 Vol.39 No.9
Nevus sebaceous is a rumor of primary epithelial germ cells that is generally first noticed at birth. Clinically, there is a yellowish waxy plaque with overlying alopecia on the scalp. Less commonly, it can be seen on the face, trunk, and extremities. Syringocystadenoma papilliferum is nthe most common benign growth from nevus sebaceous, whereas basal cell careinoma is the most frequent malignancy. The proportion of the malignant tumors occurring on nevus sebaceous is highly variable according to the published series, and there are contrevenies on the nature of these neoplasms. We experienced a rare case of nevus sebaceous, superimposed of 5 multiple type tumors at the comparatively young age; syringocystadenoma papilliferum, basal cell carcinoma, nevocellular nevus, sebaceous adenoma, and syringoma. We treated the patient with total excision, and followed up during 1 year. The patient showed no recurrence.
김지연 ( Chi Yeon Kim ),박상영 ( Sang Young Park ),오지원 ( Chee Won Oh ) 대한피부과학회 2007 대한피부과학회지 Vol.45 No.6
Pernio, or chilblains, are a localized inflammatory lesion of the skin resulting from an abnormal response to cold. The condition is characterized by cutaneous lesions located on the distal parts, such as the fingers, toes, nose and ears. Pernio develops among susceptible individuals who are exposed to non-freezing condition and most commonly occurs among young women and children. However, reports on childhood pernio are rarely found. Several conditions have been described as predisposing factors to pernio, including excessive cold exposure, low-grade vasculitis, the presence of cryoproteins, anorexia nervosa, systemic lupus erythematous and antiphospholipid antibodies. It is important, therefore, when evaluating a patient with chronic pernio who is resistant to conservative management, to exclude an underlying condition and also to determine whether additional testing is necessary. Herein, we present an uncommon case of a 5-year-old female patient with chronic pernio that may be associated with the presence of cold agglutinin. She received topical steroids prior to evaluation but no improvement was seen. Howere, treatment with calcium channel blocker, nifedipine, was of benefit to our patient. (Korean J Dermatol 2007;45(6):617∼621)