두부 외상 평가를 위한 전산화 단층 촬영 검사에서 관찰된 부비동 이상 소견의 빈도

남의철,이봉재 대한이비인후과학회 1998 대한이비인후과학회지 두경부외과학 Vol.41 No.4

경피적 강선고정을 이용한 요골 원위부 관절내 분쇄골절의 치료

안의환,오정환,신규철 건국대학교 의과학연구소 1997 건국의과학학술지 Vol.- No.7

사무직 근로자에서 직무스트레스 및 VDT작업과 목·어깨 근골격계 증상과의 관련성

이의철,김환철,정달영,김동현,임종한,박신구 대한산업의학회 2007 대한직업환경의학회지 Vol.19 No.3

광범위 베타 락탐계 항생제 분해 효소를 생성하는 폐렴간균에 의한 균혈증이 발생한 환자에서 감영의 위험 인자 및 치료 결과

강철인,김성한,방지환,김홍빈,박상원,최영주,오명돈,김의종,최강원 대한감염학회 2003 감염과 화학요법 Vol.35 No.2

목적 : 본 연구는 ESBL을 생성하는 K. pneumoniae에 의한 균혈증 환자에서 감염의 위험 인자 및 치료 결과를 알아보고자 시행하였다. 방법 : 1998년 1월부터 2002년 4월까지 혈액 배양 검사에서 동정된 K. pneumoniae를 대상으로 NCCLS guidelines과 이중 디스크 확산법(double-disk diffusion test)을 이용하여 ESBL 생성 여부를 확인하였다. ESBL 생성 균주에 의한 균혈증 환자 60명(환자군)에 대해 ESBL을 생성하지 않는 균주에 의한 균혈증 환자들(대조군)을 연령, 성별, 균혈증 발생 시점을 고려하여 1:2 또는 1:3으로 배정하였다. 총 159명의 대조군을 선정하였고 후향적인 환자-대조군 연구를 시행하였다. 결과 : 환자군과 대조군 사이에 연령, 성별, APACHE Ⅱ score, 주된 감염 부위의 유의한 차이는 없었다. ESBL을 생성하는 K. pneumoniae에 의한 균혈증이 발생할 독립적인 위험 인자에는 요관 삽입, 균혈증 발생 이전 72시간 동안 침습적인 시술을 받은 경우, 균혈증 발생 이전 30일 동안 투여받은 항생제 개수가 있었다. 초기 항생제 치료 72시간 후의 반응을 평가하였을 때, 완전 반응(complete response)은 대조군에서 더 많았고(13.3% vs. 40.3%, P<0.001), 치료 실패(treatment failure)는 환자군에서 더 많았다(33.3% vs. 11.9%, P<0.001). 7일 사망률은 환자군에서 20% (12/60), 대조군에서 15.6% (25/159)이었고(P=0.451), 30일 사망률은 환자군에서 30% (18/60), 대조군에서 24.5% (39/159)이었다(P=0.410). ESBL 생성 균주에 의한 균혈증이 있는 환자들에서 최종 항생제 치료가 부적절했던 환자들을 제외하고 30일 사망률을 분석하였을 때 효과적인 항생제 치료의 지연은 사망률을 높이지 않았다(11.1% vs. 9.1%, P=1.000). 결론 : ESBL을 생성하는 K. pneumoniae에 의한 균혈증이 있는 환자에서 초기 항균제 치료 72시간 후의 치료 반응률은 낮지만 사망률은 유의하게 증가하지 않았다. 원인균이 동정된 후 최종 치료 항생제의 선정이 적절하다면 초기에 효과적인 항생제 투여의 지연은 사망률을 유의하게 증가시키지는 않았다. Background : This study was conducted to evaluate risk factors for infection and treatment outcome of bloodstream infection due to extended spectrum β-lactamases(ESBL)-producing K. pneumoniae. Methods: ESBL production was evaluated by NCCLS guidelines and/or double-disk synergy test in K. pneumoniae blood isolates stored from January, 1998 to April, 2002. Sixty patients with bloodstream infection due to ESBL-producing K. pneumoniae (case patients) were compared with 159 matched control patients with bloodstream infection of non-ESBL-producing K. pneumoniae. Retrospective case-control study was performed. Results : There were no significant differences in age, sex, APACHE Ⅱ score, and the primary site of infection between the case and control groups. In multivariate analysis, significant independent risk factors associated with bloodstream infection due to ESBL-producing K. pneumoniae were urinary catheterization, invasive procedure within previous 72 hours, and the number of antibiotics administered within previous 30 days. In clinical response at 72 hours after initial antibiotic treatment, complete response rate was higher in the controls (13.3% vs. 40.3%, respectively, P<0.001), however, treatment failure rate was higher in the cases (33.3% vs. 11.9%, respectively, P<0.001). Overall 7-day mortality rates in the cases and the controls were was 20% (12/60) and 15.7% (25/159) (P=0.451), respectively, and overall 30-day mortality rates were 30% (18/60) and 24.5% (39/159), respectively (P=0.410). When the patients with bloodstream infection of ESBL-producing organism were evaluated and the patients who received inadequate definitive antibiotic treatment were excluded, delayed effective antibiotic treatment was found to be not associated with higher mortality. Conclusion : In patients infected with ESBL-producing K. pneumoniae bacteremia, clinical response rate at 72 hours after antimicrobial therapy was lower, but the increase of mortality rate was not significant. Delayed effective antibiotic treatment was not associated with higher mortality, when definitive appropriate antibiotic treatment was prescribed.

Streptozotocin유도 당뇨병이 백서하악 절단과두 치유에 미치는 영향의 실험적 연구

황의환,이상래,홍정표,김원철 大韓口腔顎顔面 放射線學會 1994 Imaging Science in Dentistry Vol.24 No.2

The purpose of this study was to investigate the remodeling process of the streptozotocin-induced diabetic rat's resected condyle. This experiment was performed with male Sprague-Dawly strain rats weighing approximately 250gm, which were rendered diabetic by an intravenous injection of streptozotocin(70 ㎎/㎏ body weight). After condylectomy, experimental rats were serially terminated on the 1st week, the 2nd week, the 3rd week, and the 4th week. The following termination, the mandibles were dissected out to make specimens. Each mandibular condyle was radiographed with Hitex HA-80(Hitex Co., Ltd. Japan). In addition to radiographic observation, the mandibular condyles, further decalcified and embedded in paraffin, were sectioned and stained with Hematoxylin and Eosin, Toluidine blue and Masson's trichrome. The were observed with a light microscope and a polarizing microscope. The results were as follows. 1.Soft X-ray radiograms revealed proliferation of bone after 1 week in both groups. Irregularly repaired bones and dense trabeculae were clearly observed in experimental group. 2.The resected condyles were repaired by intramembraneous and endochondral bone formation in both groups. 3.Bone tissue repair was initiated from the adjacent margin of resected bone, and cartilginous tissues were observed at the top of repaired one in both groups. 4.The number of osteoblasts of experimental group was small, compared with control group. Each osteoblast was small and flap. The thin trabeculae were irregularly formed. 5.Collagens of bone were gradually matured in both groups, but the degree of maturation was lower in experimental group. 6.Fibrous tissues covered the upper parts of repaired bone were densely arranged in the both groups. Conclusively, atrophied osteoblasts, immature collagen of bone, and this and irregular trabeculae which were characterized in the diabetes experimental group showed diabetes disturbed osteoblastic function and caused disturbance of remodeling process of bone.

호텔산업의 국제경쟁력 비교를 위한 이론적 구조모형 개발

신기철,김의근 한국관광정책학회 2001 觀光政策學硏究 Vol.7 No.1

The previous studies about international competency in hotel industry are not suggested as much as we expected. Because of this situation, this study is focused on the theoretical model development of international competency in hotel industry. Based on the process and result, this study suggested decision variables which is suited for the hotel industry. Even though the variables can be regarded as conceptual framework, this study will be necessary to research competitiveness index for hotel industry way of finding major variables.

매몰채널 pMOSFET의 짧은 채널 특성 개선에 관한 연구

이철인,장의구 중앙대학교 기술과학연구소 1994 기술과학연구소 논문집 Vol.24 No.-

We have studied the characteristics of pMOSFET with short channel effects of buried channel. Threshold voltage dependence and potential distribution with ion implantation condition and impurity profile of channel region were studied. MOSFET has buried channel in the depth of about 0.15㎛ by counter-doped boronion implantation for threshold voltage adjustment. In this paper, we have presented a method to extract process and design by computer simulation.

스포츠센터 소비자의 고객충성도에 영향을 미치는 요인에 관한 연구 : 서비스 품질과 서비스 가치를 중심으로 Centered on the quality and value of services

정의권,최영진,조현철 중앙대학교 스포츠과학연구소 2002 體育硏究 Vol.- No.17

This study centers on the quality and value of services perceived by consumers regarding factors that affect customer loyalties of sport center consumers. Study has been administered by a questionnaire survey of 200 male and female adult members of four sport centers in Seoul area. Following is the results: 1. Analyzing the relationship between demographic characteristics of sport center consumers and factors of their selection of those sport centers, there is significant difference in consumers' schooling and their family income. 2. Service quality perceived by sport center consumers appears to have a positive influence on service value. 3. Service value of sport center consumers appears to have a positive influence on customer loyalties. 4. Service quality perceived by sport center consumers appears to have a direct influence on customer loyalties. 5. Assessing the causal relationship between the service quality and value perceived by sport center consumers and customer loyalties, direct influence that the perceived service quality has on customer loyalties is stronger than indirect influence that mediated by service value.

서울 방언의 국어학적 연구

宋喆儀,兪弼在 서울시립대학교 서울학연구소 2000 서울학연구 Vol.- No.15

측두하악관절 내장증에서의 관절원판의 형태 및 골 변화에 관한 연구

박철우,황의환,이상래 대한구강악안면방사선학회 2001 Imaging Science in Dentistry Vol.31 No.1

Purpose : To investigate bone and disc configuration on MR images in internal derangement related to age. Materials and methods : MR images of 150 TMJs in 107 patients were analyzed to determine the morphologic changes. Two groups were distinguished to be correlated with age. Group 1 consisted of TMJs that were diagnosed as having anterior disc displacement with reduction (ADDwR), and Group 2 consisted of TMJs that were diagnosed as having anterior disc displacement without reduction (ADDwoR). We assessed the configuration of the articular disc, degree of anterior disc displacement, and osseous changes of TMJs. Results : The third decade (83 of 150 joints) was most frequent in this study. In the ADDwR group biconcave discs was most frequent at all ages except fifth decade, but in the ADDwoR group deformed discs was most frequent at third and forth decades. In the ADDwR group slightly displaced discs was most frequent at all ages, but in the ADDwoR group severely displaced discs was most frequent at second decade, and the degree of disc displacement was increased with aging over 30 years of age. TM joints showed osseous changes in 17% of the ADDwR group, and in 30% of the ADDwoR group. MR findings of osseous changes of the TMJ were not found to be significantly correlated with age. Conclusion : The prevalence of deformation of disc, displacement of disc, and osseous changes of TMJ was higher in the ADDwoR group than in the ADDwR group. MR findings of disc configuration and degree of disc displacement were found to be correlated with age.(Korean J Oral Maxillofac Radiol 2001;31:9-16)