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      • KCI등재

        Uniaxial Compression Properties and Compression Fatigue Performance of Selective Laser Melted Ti–6Al–4V Cellular Structure

        Ming‑Wei Wu,Jhewn‑Kuang Chen,Mo‑Kai Tsai,Pei Wang,Tien‑Lin Cheng,Bo‑Huan Lin,Po‑Hsing Chiang,Annadurai Dhinakar 대한금속·재료학회 2022 METALS AND MATERIALS International Vol.28 No.1

        The selective laser melted (SLM) Ti–6Al–4V cellular solid is a promising material in biomedical and other applications. The mechanical properties of the SLM Ti–6Al–4V cellular material are predominantly controlled by the design of the cellular structure. The objective of this study was to investigate the uniaxial compressive properties and compressive fatigueperformance of the SLM Ti–6Al–4V cellular solid with a new cuboctahedron unit cell reinforced by four diagonal strutsand two horizontal struts along the X and Y axes. The infuences of hot isostatic pressing (HIP) on the various mechanicalproperties were also examined. The results showed a smoother stress–strain curve and fewer stress oscillations in the HIPspecimen than in the SLM specimen. The HIP process slightly decreased the yield strength of the SLM sample from 55 to52 MPa. Under uniaxial compressive stress, the SLM and HIP specimens exhibited layer-by-layer fracture and diagonalshear fracture, respectively. Furthermore, the HIP treatment signifcantly increased the fatigue performance and improved thefatigue endurance ratio at 106cycles from 0.15 to 0.35. The HIP treatment contributed to several positive efects, includingphase transformation from brittle α′ to α + β, the elimination of strut porosity and residual stress, an increase in lath size,and a better combination of strength and ductility, thereby improving the fatigue performance. The efects of stress mode onthe fracture mechanism were also clarifed using in situ observation in combination with digital image correlation.

      • KCI등재

        朱光潛的比較詩學思想及其實踐

        鐘名誠 한국중국문화학회 2002 中國學論叢 Vol.14 No.-

        Zhu Guangqian is a pioneer of modern Chinese comparative poetics. In the course of the exchange between oriental culture and western culture, he looked into the Chinese modern poetic movement with his international perspective. In his research of Chinese and western poems, he applied the general principles and ideas of comparative poetics, i.e. the applicable value principles; the mutually depicting principles; the principles of the sense of history; the comprehensive comparison principles and etc., to explore the art of the Chinese and western poems Zhu has made great valuable efforts in the comparative research of western and Chinese poems and had made great contributions to the healthy development of Chinese modern poems. Today whenever we encounter any difficulties in our modern Chinese poems, we will refer to Zhu's comparative poetics thoughts. We find Zhu's thoughts still very practical and instructive.

      • 녹음 구어 제시가 중도정신지체 성인여성의 목욕 능력 개선에 미치는 효과

        鄭如意,陳明聰,陳政見 대구대학교 특수교육재활과학연구소 2006 再活科學硏究 Vol.24 No.2

        1. This study aimed to explore the effect of recorded auditory prompts on helping an adult with profound mental retardation to take bath independently. 「A-B-C-A-C」design, a kind of single-subject experiment was adopted. Three phases, baseline phase, intervention phase(B): auditory prompt, and intervention phase(C): recorded auditory prompt were included. A female with profound mental retardation participated in the experiment. It took over seven months to finishing the intervention. The results of the experiment indicated that auditory prompts, whether human auditory prompt or recorded prompt, could help the client to take bath more independently. The families of the client also regarded recorded auditory prompt was a feasible solution. Based on the result, there were some suggestions for the further research. 본 연구의 목적은 녹음 구어 제시를 이용해서 극 중도 지능장애 성인 여성 스스로 목욕 동작을 완성 할 수 있도록 도와주는 효과에 대한 연구입니다. 본 연구에 사용하는 연구법은 ⌜A-B-A-C-A-C⌟역 설계이다. 기선기의(A)개입一(B)인공구어제시 개입二(C)녹음 구어 제시로 나누어졌다. 실험기간은 모두 7개월 반이었다. 연구결과는 피 실험자가 스스로 목욕할 때와 비교했을 때 인공구어 제시와 녹음구어 제시는 모두 피 실험자가 목욕 동작을 완성 하는 데에 효과가 있는 것으로 나타났다. 이 외에도 녹음 구어 제시는 피 실험자 가족들도 받아들일 수 있다. 본 연구 결과에 근거해서 연구자들은 미래 응용과 연구에 대한 건의도 제출하였다.

      • KCI등재

        Visual Servoing of a Micro Quadrotor Landing on a Ground Platform

        Cheng-Ming Huang,Ming-Li Chiang,Tzu-Shun Hung 제어·로봇·시스템학회 2017 International Journal of Control, Automation, and Vol.15 No.6

        This paper presents a visual servoing methodology for landing a quadrotor-type micro aerial vehicle(MAV) on a ground platform in an indoor environment. Since space in an indoor environment is usually limited, thesizes of the MAV and the landing platform employed here have to be small. Thus, visual servoing based on two pinholecameras mounted on the front and bottom of a MAV is suitable for such a scenario. A powerful computationalprocessing unit for image or control processing and a high capacity battery for charging the MAV are equipped onthe ground platform. The captured images and the flying control commands are transmitted between the groundplatform and the MAV through a wireless network. Visual feature extraction of the landing platform is proposedto detect a specific image pattern on the landing platform. Flying control strategies, with the cameras switching,are developed to search for and approach the landing platform. Alignment control during the landing procedure isdesigned using multi-level fuzzy logic control with the target position error on the image. The overall performanceof the landing algorithm is validated by several online experiments with a commercialized MAV.

      • SCIESCOPUSKCI등재

        MAXIMAL SPACE-LIKE HYPERSURFACES IN H<sub>1</sub><sup>4</sup>(-1) WITH ZERO GAUSS-KRONECKER CURVATURE

        CHENG QING-MING,SUH YOUNG JIN Korean Mathematical Society 2006 대한수학회지 Vol.43 No.1

        In this paper, we study complete maximal space-like hypersurfaces with constant Gauss-Kronecker curvature in an antide Sitter space $H_1^4(-1)$. It is proved that complete maximal spacelike hypersurfaces with constant Gauss-Kronecker curvature in an anti-de Sitter space $H_1^4(-1)$ are isometric to the hyperbolic cylinder $H^2(c1){\times}H^1(c2)$ with S = 3 or they satisfy $S{\leq}2$, where S denotes the squared norm of the second fundamental form.

      • KCI등재

        The Antiproliferation Activity of Ganoderma formosanum Extracts on Prostate Cancer Cells

        ( Cheng-yen Chiang ),( Kai-di Hsu ),( Yen-yi Lin ),( Chang-wei Hsieh ),( Jui-ming Liu ),( Tze-ying Lu ),( Kuan-chen Cheng ) 한국균학회 2020 Mycobiology Vol.48 No.3

        Androgen-independent prostate cancer accounts for mortality in the world. In this study, various extracts of a medical fungus dubbed Ganoderma formosanum were screened for inhibition of DU145 cells, an androgen-independent prostate cancer cell line. Results demonstrated that both hexane (GF-EH) and butanol (GF-EB) fraction of G. formosanum ethanol extract inhibited DU145 cell viability in a dose-dependent manner. GF-EH induced cell-cycle arrest in G1 phase of DU145 cells via downregulation of cyclin E2 protein expression. In addition, GF-EB triggered extrinsic apoptosis of DU145 cells by activating caspase 3 gene expression resulting in programed cell death. Above all, both GF-EH and GF-EB show lower toxicity to normal human fibroblast cell line compared to DU145 cell, implying that they possess specific drug action on cancer cells. This study provides a molecular basis of G. formosanum extract as a potential ingredient for treatment of androgen-independent prostate cancer.

      • KCI등재

        A New Calculation Model for Calcium Requirements After Parathyroidectomy in Patients With Secondary Hyperparathyroidism

        Ming Cheng,Qian Zhang,Mengjing Wang,Bihong Huang,Ye Tao,Chunyan Fan,Hongying Wang,Minmin Zhang 대한이비인후과학회 2023 Clinical and Experimental Otorhinolaryngology Vol.16 No.3

        Objectives. We aimed to develop a new calculation model for calcium requirements in dialysis patients following parathy-roidectomy. Methods. A total of 98 patients with secondary hyperparathyroidism receiving parathyroidectomy from January 2014 toJanuary 2022 were enrolled in this study. Among these patients, 78 were randomly selected for construction of thecalcium requirement calculation model, and the remaining 20 patients were selected for model validation. The calci-um requirement model estimated the total calcium supplementation for 1 week after surgery using variables withsignificant relationships in the derivation group by stepwise multiple linear regression analysis. Bias, precision, andaccuracy were measured in the validation group to determine the performance of the model. Results. The model was as follows: calcium requirement for 1 week after surgery =33.798–8.929×immediate postoperativecalcium+0.190×C-reactive protein–0.125×age+0.002×preoperative intact parathyroid hormone+0.003×preopera-tive alkaline phosphatase (R2 =0.8). The model was successfully validated. Conclusion. We generated a novel model to guide calcium supplementation. This model can assist in stabilizing the serumcalcium levels of patients during the early postoperative period. Furthermore, it contributes to the individualized andprecise treatment of hypocalcemia in patients following parathyroidectomy.

      • Tenofovir Alafenamide for Chronic Hepatitis B Patients with Advanced Fibrosis and Partial Virologic Responses to Oral Nucleos(T)Ide Analogues- Interim Report

        ( Ming-lung Yu ),( Ming-lun Yeh ),( Chi-yi Chen ),( Pin-nan Cheng ),( Ming-jong Bair ),( Jyh-jou Chen ),( Ching-chu Lo ),( Chi-ming Tai ),( Ching-yang Tsai ),( Kuo-chih Tseng ),( Chien-hung Chen ),( C 대한간학회 2020 춘·추계 학술대회 (KASL) Vol.2020 No.1

        Aims: Insufficient data regarding the treatment strategy for partial response to nucleot(s)ide analogue (NUC) raised the aim of investigating tenofovir alafenamide (TAF) switching for chronic hepatitis B (CHB) patients with advanced fibrosis and partial response to other NUCs. Methods: CHB patients with advanced fibrosis (stage 3 or 4) and under NUC (except TAF) therapy with detectable hepatitis B virus (HBV) DNA for >52 weeks are enrolled to TAF 25 mg/day for 96 weeks. The objectives are viral suppression, alanine aminotransferase (ALT) normalization and safety. Results: From Feb. 2019, 34 patients, including 21 (61.8%) with entecavir, 10 (29.4%) TDF and 3 (8.8%) lamivudine or adefovir, were enrolled (15 [44.1%] male, median 53 years). The fibroscan demonstrated a mean of 10.5 kPa (7 [20.6%] cirrhotic). Sixteen (47.1%) patients were HBV e antigen positive, seven (20.6%) had YMDD mutation. The median HBV DNA level declined from 68.5 IU/mL at enrollment to 27.0 IU/mL at 4<sup>th</sup> week, and undetectable at 12<sup>th</sup>, 24<sup>th</sup>, 36<sup>th</sup> week, respectively, after TAF switching, with undetectable HBV DNA in 14/34 (41.2%), 17/33 (51.5%), 15/25 (60.0%), and 9/15 (60.0%) patients and rate of ALT normalization (≤40 U/L) of 85.3%, 85.3%, 84.8%, 92.0%, and 80.0%, respectively, after TAF switching. (figure 1) Two patients experienced transient virological breakthrough and another one developed at the final time follow up. Serum creatinine and eGFR levels were stable after TAF switching (figure 1). Two patients early terminated including one at 12<sup>th</sup> week due to personal reason, and another one accidently died at 20<sup>th</sup> week due to acute heart attack. Others suffered only mild degrees of adverse events which were considered unrelated to treatment. Conclusions: The preliminary results demonstrated the TAF switching is effective and safe in viral suppression for CHB patients with advanced fibrosis and partial virologic responses to other NUCs.

      • Real-Time Object Detection and Tracking on a Moving Camera Platform

        Cheng-Ming Huang,Yi-Ru Chen,Li-Chen Fu 제어로봇시스템학회 2009 제어로봇시스템학회 국제학술대회 논문집 Vol.2009 No.8

        This paper presents a real-time tracking system to detect and track multiple moving objects on a controlled pan-tilt camera platform. In order to describe the relationship between the targets and camera in this tracking system, the input/output hidden Markov model (HMM) is applied here in the well-defined spherical camera coordinate. Since the detection and tracking for different targets are performed at the same time on a moving camera platform, the detection and tracking processes must be fast and effective. A hybrid detection algorithm which combines the target’"s color and optical flow information is proposed here. A two layer tracking architecture is then utilized for tracking the detected target. The bottom level utilizes the Kanade-Lucas-Tomasi (KLT) feature point tracker which identifies the local point correspondence across image frames. The particle filter at top level, which maintains the relation between target and feature points, estimates the tracked target state. The overall performance has been validated in the experiments.

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