COMMUNITY PARTICIPATION IN AND BENEFITS OF TOURISM DEVELOPMENT IN THE TURPAN VALLEY, XINJIANG AUTONOMOUS REGION OF CHINA

Cheng,Soo May,Yang,Li,Dong,Lin 세계문화관광학회 2007 Conference Proceedings Vol.8 No.0

While western scholars such as Jamal and Gertz (1995), Tosun (2005), Fallon and Kriwoken (2003), usually presume that community participation is critical to sustainable tourism development, Chinese scholar Wenjun Li (2006) boldly states that it is possible for a community to achieve benefits of tourism development despite weak involvement in the planning and management of a tourist destination. Our survey of government officials, tourist business operators and residents in seven locations in the World Heritage-listed Turpan Valley in the Xinjiang province found that top-down, government-led participation is necessary and desirable, and does not detract from stakeholders' perception that they are sharing in the benefits of tourism development in the region.

Effects of Mold Growth on Building Materials by Different Environments in Taiwan

An Cheng,Yu Hsin,Wei-Ting Lin 대한토목학회 2014 KSCE Journal of Civil Engineering Vol.18 No.4

The main of study is to investigate the effect of moisture variation and micro-structure on the growth mold at surface of buildingmaterials. The two different water-cement ratio of mortars (w/c = 0.4, 0.6), brick and tiles were used in this study. The mercuryIntrusion Porosity-Meter (MIP) was used to determine the pore distribution of building materials. The moisture variation of materialswas recorded in constant climate chamber (25oC, relative humidity 80%), general indoor environment (28oC, relative humidity 55%)and water damage simulation environment. The results indicated that the pore size and distribution will affect the surface water ratioand moisture content of materials. The surface water ratio of specimen was affected by different environment seriously. The surfacewater ratio was an important factor in mold growth.

Tissue Quality Comparison Between Heparinized Wet Suction and Dry Suction in Endoscopic Ultrasound-Fine Needle Biopsy of Solid Pancreatic Masses: A Randomized Crossover Study

Lin Meng-Ying,Wu Cheng-Lin,Su Yung-Yeh,Huang Chien-Jui,Chang Wei-Lun,Sheu Bor-Shyang 거트앤리버 소화기연관학회협의회 2023 Gut and Liver Vol.17 No.2

Background/Aims: A high-quality sample allows for next-generation sequencing and the administration of more tailored precision medicine treatments. We aimed to evaluate whether heparinized wet suction can obtain higher quality samples than the standard dry-suction method during endoscopic ultrasound (EUS)-guided biopsy of pancreatic masses. Methods: A prospective randomized crossover study was conducted. Patients with a solid pancreatic mass were randomly allocated to receive either heparinized wet suction first or dry suction first. For each method, two needle passes were made, followed by a switch to the other method for a total of four needle punctures. The primary outcome was the aggregated white tissue length. Histological blood contamination, diagnostic performance and adverse events were analyzed as secondary outcomes. In addition, the correlation between white tissue length and the extracted DNA amount was analyzed. Results: A total of 50 patients were enrolled, and 200 specimens were acquired (100 with heparinized wet suction and 100 with dry suction), with one minor bleeding event. The heparinized wet suction approach yielded specimens with longer aggregated white tissue length (11.07 mm vs 7.96 mm, p=0.001) and less blood contamination (p=0.008). A trend towards decreasing tissue quality was observed for the 2nd pass of the dry-suction method, leading to decreased diagnostic sensitivity and accuracy, although the accumulated diagnostic performance was comparable between the two suction methods. The amount of extracted DNA correlated positively to the white tissue length (p=0.001, Spearman̕s ρ=0.568). Conclusions: Heparinized wet suction for EUS tissue acquisition of solid pancreatic masses can yield longer, bloodless, DNA-rich tissue without increasing the incidence of adverse events (ClinicalTrials.gov. identifier NCT04707560).

Effect of Caponization on Muscle Composition, Shear Value, ATP Related Compounds and Taste Appraisal in Taiwan Country Chicken Cockerels

Lin, Cheng-Yung,Lin, Liang-Chuan,Hsu, Jenn-Chung Asian Australasian Association of Animal Productio 2011 Animal Bioscience Vol.24 No.7

An experiment was conducted to determine the effects of caponization on the muscle composition, ATP-related compounds, the shear values, the taste panel scores and the muscle fiber areas of Taiwan country chicken cockerels. At 10 wks of age, cockerels were divided into two groups: caponized and untreated. Birds were fed grower and finisher diets ad libitum in an eighteen-week experimental period. Results showed that capons contained significantly greater muscle fat content, less breast and thigh muscle moisture content, shear value and muscle fiber area (p<0.05) than those of intact birds. However, neither treatment groups differed significantly (p>0.05) in breast and thigh muscle protein content. Compared with the intact birds, the capons contained significantly (p<0.05) less muscle ash content in the breasts, but did not differ significantly (p>0.05) in thigh muscle ash content. The breast muscle IMP and ATP+ADP+AMP+IMP contents in the intact birds were significantly (p<0.05) higher than those in the capons. The intact birds had significantly (p<0.05) higher ATP and AMP contents than did the capons as well as significantly (p<0.05) less ADP and inosine (HxR) contents in the thigh and breast muscles. The Hypoxanthine (Hx) content of the thighs in the intact birds was significantly (p<0.05) higher than that in the capons; however, there was an adverse effect on the breast muscle Hx content. The breast muscle K value in the intact birds was significantly (p<0.05) lower than that in the capons. The capons produced significantly (p<0.05) higher taste panel scores than did the intact birds for both flavor and juiciness of thigh muscle as well as for flavor and tenderness of breast muscle.

DEA모형과 Tier분석을 이용한 한,중 주요 항만배후단지 효율성 분석

( Cheng Lin Qing ),( Ju Mong Na ) 국제지역학회 2013 국제지역학회 춘계학술대회 Vol.2013 No.-

본 연구는 DEA 기법을 적용하여 동북아지역에서 컨테이너 처리량이 30위 안에 들어있는 한국과 중국의 항만배후단지를 대상으로 상대적 효율성을 분석하였다. 비효율 적인 항만배후단지들의 Tier분석을 통해 벤치마킹 대상인 항만배후단지들을 찾아냄으로써 경로군집을 발견하였다. 주요 분석결과는 다음과 같다. 첫째, 전통적인 DEA 분석에서 CCR 모형을 이용하여 연구대상의 상대적인 효율성을 분석한 결과, 홍콩 항만배후단지가 2008년부터 2012년까지, 심천 항만배후단지는 2008년부터 2009년까지, 광저우 항만배후단지는 2010년부터 2012년까지 효율적인 벤치마킹 항만배후단지로 나타났다. 둘째, Post-DEA를 활용하여 2012년의 비효율적인 항만배후단지들에 대해 Tier 1단계의 분석을 하였는데 심천항만배후단지, Tier 2단계에서는 상하이와 청도 항만배후단지, Tier 3단계에서는 닝보 항만배후단지가 효율적인 벤치마킹 대상으로 나타났다. 셋째, 이를 바탕으로 한국의 부산, 광양, 인천 항만배후단지에 대해서 Tier 단계별로 단기→중기→장기로 나누어서 실제적으로 실현가능성이 있는 단계별 벤치마킹 대상을 제시하였다. This study analyzed the relative efficiency of the port hinterland which was ranked in 30th in terms of container throughput in South Korea and China by applying the DEA technique of non-parametric analysis of efficiency. Path formation has been found by the Tier analysis of inefficient port hinterland to find the target of benchmarking. The main analysis results are as follows. First, analysis of the relative efficiency of the study using CCR model in traditional DEA analysis, Hongkong port hinterland from 2008 to 2012, Shenzhen from 2008 to 2009, and Guangzhou from 2010 to 2012 had turned to be the effective benchmarking port hinterland. Second, there are different result of the efficient benchmarks based on Tier analysis using Post-DEA regarding inefficient port hinterlands in 2012. The result indicates that Shenzhen at the Tier level 1, Shanghai and Qingdao at the Tier level 2, and Ningbo at the Tier level 3 were the effective benchmarks at each Tier level. Third, based on the result, this study suggests a step-by-step practical and feasible benchmark for Busan, Gwangyang, and Incheon port hinterland in Korea to fulfill Tier analysis by long-term→mid-term→short-term.

Effective Antiviral Activity of the Tyrosine Kinase Inhibitor Sunitinib Malate against Zika Virus

Lin Chen-Sheng,Huang Su-Hua,Yan Bo-Yu,Lai Hsueh-Chou,Lin Cheng-Wen 대한감염학회 2021 Infection and Chemotherapy Vol.53 No.4

Introduction: Zika virus (ZIKV), a mosquito-borne flavivirus, causes the outbreaks of Latin America in 2015 - 2016, with the incidence of neurological complications. Sunitinib malate, an orally bioavailable malate salt of the tyrosine kinase inhibitor, is suggested as a broadspectrum antiviral agent against emerging viruses like severe acute respiratory syndrome coronavirus (SARS-CoV) and SARS-CoV-2. Materials and Methods: This study investigated the antiviral efficacy and antiviral mechanisms of sunitinib malate against ZIKV infection using cytopathic effect reduction, virus yield, and time-of-addition assays. Results: Sunitinib malate concentration-dependently reduced ZIKV-induced cytopathic effect, the expression of viral proteins, and ZIKV yield in supernatant with 50% inhibitory concentration (IC50) value of 0.015 μM, and the selectivity index of greater than 100 against ZIKV infection, respectively. Sunitinib malate had multiple antiviral actions during entry and post-entry stages of ZIKV replication. Sunitinib malate treatment at entry stage significantly reduced the levels of ZIKV RNA replication with the reduction of (+) RNA to (-) RNA ratio and the production of new intracellular infectious particles in infected cells. The treatment at post-entry stage caused a concentration-dependent increase in the levels of ZIKV (+) RNA and (-) RNA in infected cells, along with enlarging the ratio of (+) RNA to (-) RNA, but caused a pointed increase in the titer of intracellular infectious particles by 0.01 and 0.1 μM, and a substantial decrease in the titer of intracellular infectious particles by 1 μM. Conclusion: The study discovered the antiviral actions of sunitinib malate against ZIKV infection, demonstrating a repurposed, host-targeted approach to identify potential antiviral drugs for treating emerging and global viral diseases.

The Study of the Cycle Time Improvement by Work-In-Process Statistical Process Control Method for IC Foundry Manufacturing

Lin, Yu-Cheng,Tsai, Chih-Hung,Li, Rong-Kwei,Chen, Ching-Piao,Chen, Hsien-Ching The Korean Society for Quality Management 2008 The Asian Journal on Quality Vol.9 No.3

The definition of cycle time is the time from the wafer start to the wafer output. It usually takes one or two months to get the product since customer decides to produce it. The cycle time is a critical factor for customer satisfaction because it represents the response time to the market. Long cycle time reflects the ineffective investment for the capital. The cycle time is very important for foundry because long cycle time will cause customer unsatisfied and the order loss. Consequently, all of the foundries put lots of human source in the cycle time improvement. Usually, we make decisions based on the experience in the cycle time management. We have no mechanism or theory for cycle time management. We do work-in-process (WIP) management based on turn rate and standard WIP (STD WIP) set by experiences. But the experience didn't mean the optimal solution, when the situation changed, the cycle time or the standard WIP will also be changed. The experience will not always be applicable. If we only have the experience and no mechanism, management will not be work out. After interview several foundry fab managers, all of the fab can't reflect the situation. That is, all of them will have an impact period after product mix or utilization varied. In this study, we want to develop a formula for standard WIP and use statistical process control (SPC) concept to set WIP upper/lower limit level. When WIP exceed the limit level, it will trigger action plans to compensate WIP Profile. If WIP Profile balances, we don't need too much WIP. So WIP level could be reduced and cycle time also could be reduced.

THE AMERICAN ECONOMY IN THE 1970S : A BACKWARD LOOK

Cheng, Chai Lin 한국아메리카학회 1983 美國學論集 Vol.14,15 No.-

Rapid Preparation of Total Nucleic Acids from E. coli for Multi-purpose Applications

Cheng, Lin,Li, Tai-Yuan,Zhang, Yi Korean Society for Biochemistry and Molecular Biol 2004 Journal of biochemistry and molecular biology Vol.37 No.3

Separate protocols are commonly used to prepare plasmid DNA, chromosomal DNA, or total RNA from E. coli cells. Various methods for the rapid preparation of plasmid DNA have been developed previously, but the preparation of the chromosomal DNA and total RNA are usually laborious. We report here a simple, fast, reliable, and cost-effective method to extract total nucleic acids from E. coli by direct lysis of the cells with phenol. Five distinct and sharp bands, which correspond to chromosomal DNA, plasmid DNA, 23S rRNA, 16S rRNA, and a mixture of small RNA, were observed when analyzing the prepared total nucleic acids on a regular 1-2% agarose gel. The simple and high-quality preparation of the total nucleic acids in a singe tube allowed us to rapidly screen the recombinant plasmid, as well as to simultaneously monitor the change of the plasmid copy number and rRNA levels during the growth of E. coli in the liquid medium.

Rapid Preparation of Total Nucleic Acids from E. coli for Multi-purpose Applications

( Lin Cheng ),( Tai Yuan Li ),( Yi Zhang ) 생화학분자생물학회 2004 BMB Reports Vol.37 No.3

Separate protocols are commonly used to prepare plasmid DNA, chromosomal DNA, or total RNA from E. coli cells. Various methods for the rapid preparation of plasmid DNA have been developed previously, but the preparation of the chromosomal DNA and total RNA are usually laborious. We report here a simple, fast, reliable, and cost-effective method to extract total nucleic acids from E. coli by direct lysis of the cells with phenol. Five distinct and sharp bands, which correspond to chromosomal DNA, plasmid DNA, 23S rRNA, 16S rRNA, and a mixture of small RNA, were observed when analyzing the prepared total nucleic acids on a regular 1-2% agarose gel. The simple and high-quality preparation of the total nucleic acids in a singe tube allowed us to rapidly screen the recombinant plasmid, as well as to simultaneously monitor the change of the plasmid copy number and rRNA levels during the growth of E. coli in the liquid medium.