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Classification of particles in particle-laden stream through a stainless steel fibrous filter
Cheng-Hsiung Huang,Chung-Liang Chang,Tser-Sheng Lin 한국화학공학회 2007 Korean Journal of Chemical Engineering Vol.24 No.3
investigation experimentally explores the penetration curve of particles shot onto a stainles steelt-ing, on the particle penetration was examined at various flow rates, nozzle diameters and dimensionless particle diam-eters, Sqrt(Stk). The penetration of the flat surface by particles was also determined for comparison. Experimental re-sults demonstrate that oleic acid particles larger than Sqrt(Stk)50 are collected on the stainless steel fibrous filter witha low penetration, while smaller particles stay in the particle-laden stream with high penetration. The penetration ofpotassium chloride particles exceeds that of oleic acid particles, because potassium chloride particles bounce off thestainless steel fibrous filter and the flat surface. Particles bounce of the metal filter less easily than the flat surface.Coating the stainless steel fibrous filter with oil effectively reduces problems of particle bounce. The potasium chlorideparticles sucked the coated oil forming a small mountain on the surface. When the loaded particle mass on the coatedstainless steel fibrous filter ranges between 0.4 and 2.3 mg, Sqrt(Stk)50 is a constant 0.35.
Removal of particulate matter from an air stream by a packed dielectric barrier discharge
Cheng-Hsiung Huang,Chung-Liang Chang 한국화학공학회 2008 Korean Journal of Chemical Engineering Vol.25 No.6
This study elucidates the feasibility of using a packed dielectric barrier discharge approach to remove particulate matter from an air stream. The experimental results reveal that the particle removal efficiency of the packed dielectric barrier discharge system rose to 92.2% for 0.3 μm particles as the discharge voltage was increased to 20 kV at an operating frequency of 60 Hz. Only when the discharge voltage was sufficiently high to remove particulate matter did the particle removal efficiency increase with the operating frequency. The power required to adjust the discharge voltage was less than that required to adjust the operating frequency at the particular removal efficiency. Accordingly, energy can be saved in a packed dielectric barrier discharge system by adjusting the discharge voltage rather than the operating frequency to remove particulate matter from the air stream.
Cheng-Chen Chang,Ming-Hong Hsieh,Jong-Yi Wang,Nan-Ying Chiu,Yu-Hsun Wang,Jeng-Yuan Chiou,Hsiang-Hsiung Huang,Po-Chung Ju 대한신경정신의학회 2018 PSYCHIATRY INVESTIGATION Vol.15 No.11
Objective Several cell line studies have demonstrated thioridazine’s anticancer, multidrug resistance-reversing and apoptosis-inducing properties in various tumors. We conducted this nationwide population-based study to investigate the association between thioridazine use and cancer risk among adult patients with schizophrenia. Methods Based on the Psychiatric Inpatient Medical Claim of the National Health Insurance Research Database of Taiwan, a total of 185,689 insured psychiatric patients during 2000 to 2005 were identified. After excluding patients with prior history of schizophrenia, only 42,273 newly diagnosed patients were included. Among them, 1,631 patients ever receiving thioridazine for more than 30 days within 6 months were selected and paired with 6,256 randomly selected non-thioridazine controls. These patients were traced till 2012/12/31 to see if they have any malignancy. Results The incidence rates of hypertension and cerebrovascular disease were higher among cases than among matched controls. The incidence of hyperlipidemia, coronary artery disease and chronic pulmonary disease did not differ between the two groups. By using Cox proportional hazard model for cancer incidence, the crude hazard ratio was significantly higher in age, hypertension, hyperlipidemia, cerebrovascular disease, coronary artery disease and chronic pulmornary disease. However, after adjusting for other covariates, only age and hypertension remained significant. Thioridazine use in adult patients with schizophrenia had no significant association with cancer. Conclusion Despite our finding that thioridazine use had no prevention in cancer in adult patients with schizophrenia. Based on the biological activity, thioridazine is a potential anticancer drug and further investigation in human with cancer is warranted.
Cheng-Yen Chang,Hsin-Kai Wang,Hong-Jen Chiou,Yi-Hong Chou,Tain-Hsiung Chen,See-Ying Chiou 대한영상의학회 2006 Korean Journal of Radiology Vol.7 No.1
Objective: We wanted to assess the usefulness of four-dimensional (4D) ultrasonography (US), i.e., real-time three-dimensional US, as an adjunct for performing various US-guided interventional procedures in superficial lesions. Materials and Methods: Thirty-three patients were referred for US-guided interventional procedures for superficial lesions, including core biopsy in 19, fineneedle aspiration in eight, therapeutic drug injection in four and needle puncture in two. The procedures were performed under 4D US guidance. We reviewed the pathologic/cytologic results of the core biopsies or needle aspirations, and also the outcomes of drug injection or needle puncture. Results: For all the patients who underwent 4D US-guided core biopsy, the specimens were adequate for making the pathological diagnosis, and specimens were successfully obtained for those patients who underwent 4D US-guided aspiration. The patients treated with 4D US-guided therapeutic drug injection or needle puncture had a good response. No major procedure-related complications occurred. The procedural times were similar to those procedural times with using two-dimensional US. Conclusion: Combining the two dimensional and 4D US techniques aids the physician when performing US-guided interventional procedures for the superficial lesions.
Tai, Cheng-Jeng,Pan, Chin-Kwun,Chen, Ching-Shyang,Hung, Chin-Sheng,Wu, Chih-Hsiung,Chiou, Hung-Yi Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.3
Objective: The optimal duration of adjuvant trastuzumab treatment in patients with HER2-positive breast cancer is not known. The aim of this study was to evaluate the efficacy of 6 months of adjuvant trastuzumab treatment in patients with stage II or III HER2-positive breast cancer. Methods: The records of patients with HER2-positive stage II or III breast cancer who were admitted to the Breast Center of Taipei Medical University Hospital and Yuan's General Hospital between 2000 and 2008 were reviewed. All patients received adjuvant trastuzumab at an initial dose of 4 mg/kg followed by a maintenance dose of 2 mg/kg/week for 22 weeks in combination with chemotherapy. Results: A total of 51 patients were included with a mean age of 46.9 years. Approximately 55% of the patients had stage III disease. The mean follow-up time from initiation of treatment was 45.2 months (range, 0.9 to 85 months). During follow-up, 46 patients (90.2%) did not experience tumor recurrence. The mean estimated disease free survival was 80.2 months. The estimated 1-, 2-, 5-, and 7-year survival rates were 97.9%, 93.1%, 93.1%, and 93.1%, respectively. The most common adverse effects were gastrointestinal symptoms (21.6%), chills (17.6%), dizziness (9.8%), and bone pain (7.8%). No cardiac or hematologic adverse events occurred. Conclusion: Adjuvant therapy with trastuzumab for 6 months resulted in a clinical benefit in patients with HER2-positive breast cancer.
Application of recursive SSA as data pre-processing filter for stochastic subspace identification
Chin-Hsiung Loh,Yi-Cheng Liu 국제구조공학회 2013 Smart Structures and Systems, An International Jou Vol.11 No.1
The objective of this paper is to develop on-line system parameter estimation and damage detection technique from the response measurements through using the Recursive Covariance-Driven Stochastic Subspace identification (RSSI-COV) approach. To reduce the effect of noise on the results of identification, discussion on the pre-processing of data using recursive singular spectrum analysis (rSSA) is presented to remove the noise contaminant measurements so as to enhance the stability of data analysis. Through the application of rSSA-SSI-COV to the vibration measurement of bridge during scouring experiment, the ability of the proposed algorithm was proved to be robust to the noise perturbations and offers a very good online tracking capability. The accuracy and robustness offered by rSSA-SSI-COV provides a key to obtain the evidence of imminent bridge settlement and a very stable modal frequency tracking which makes it possible for early warning. The peak values of the identified 1st mode shape slope ratio has shown to be a good indicator for damage location, meanwhile, the drastic movements of the peak of 2nd mode slope ratio could be used as another feature to indicate imminent pier settlement.
SSA-based stochastic subspace identification of structures from output-only vibration measurements
Chin-Hsiung Loh,Yi-Cheng Liu,Yi-Qing Ni 국제구조공학회 2012 Smart Structures and Systems, An International Jou Vol.10 No.4
In this study an output-only system identification technique for civil structures under ambient vibrations is carried out, mainly focused on using the Stochastic Subspace Identification (SSI) based algorithms. A newly developed signal processing technique, called Singular Spectrum Analysis (SSA), capable to smooth a noisy signal, is adopted for preprocessing the measurement data. An SSA-based SSI algorithm with the aim of finding accurate and true modal parameters is developed through stabilization diagram which is constructed by plotting the identified system poles with increasing the size of data matrix. First, comparative study between different approaches, with and without using SSA to pre-process the data, on determining the model order and selecting the true system poles is examined in this study through numerical simulation. Finally, application of the proposed system identification task to the real large scale structure: Canton Tower, a benchmark problem for structural health monitoring of high-rise slender structures, using SSA-based SSI algorithm is carried out to extract the dynamic characteristics of the tower from output-only measurements.