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A Thrombus Growth Model Based on Level Set Methods
Chaoqing Ma,Oubong Gwun 한국스마트미디어학회 2016 스마트미디어저널 Vol.5 No.1
macroscale model and microscale model. The former is used to model the plasma flow with Navier-Stokes equations, and the latter is used to model the platelets adhesion and aggregation, thrombus motion, and the surface expansion of thrombus. The force acting on platelets and thrombus from plasma is modeled by the drag force, and the forces from biochemical reactions are modeled by the adhesion force and the aggregation force. As more platelets are merged into the thrombus, the thrombus surface expands. We proposed a thrombus growth model for simulating the expansion of thrombus surface and tracking the surface by Level Set Methods. We implemented the computational model. The model performs well, and the experimental results show that the shape of thrombus in level set expansion form is similar with the thrombus in clinical test.
Vanishing Points Detection in Indoor Scene Using Line Segment Classification
Chaoqing Ma(마조청),Oubong Gwun(권오봉) 한국콘텐츠학회 2013 한국콘텐츠학회논문지 Vol.13 No.8
본 논문에서는 선분분류를 이용하여 실내영상의 소실점을 검출하는 방법을 제안한다. 실내영상을 효율적으로 검출하기 위하여 2 단계로 소실점을 추출한다. 1 단계에서는 이미지가 1 점 투시인지 2 점 투시인지 판별한다. 만일 이미지가 2 점 투시이면, 선분분류를 위하여 검출된 소실점을 지나는 수평선을 구한다. 2단계에서는 선분분류를 이용하여 2 개의 소실점을 정확히 검출한다. 또 본 논문에서는 인공영상과 이미지 DB를 이용하여 제안한 방법을 평가하였다. 노이즈를 첨가한 인공 영상에 대해서는 노이즈가 60%를 차지할 때까지 검출한 소실점과 실제 소실점과의 차이가 16 픽셀 이하였다. A. Quattoni 와 A. Torralba가 제안한 이미지 DB를 이용한 평가에서는 87% 이상의 이미지에 대하여 소실점을 검출하였다. This paper proposes a method to detect vanishing points of an indoor scene using line segment classification. Two-stage vanishing points detection is carried out to detect vanishing point in indoor scene efficiently. In the first stage, the method examines whether the image composition is a one-point perspective projection or a two-point one. If it is a two-point perspective projection, a horizontal line through the detected vanishing point is found for line segment classification. In the second stage, the method detects two vanishing points exactly using line segment classification. The method is evaluated by synthetic images and an image DB. In the synthetic image which some noise is added in, vanishing point detection error is under 16 pixels until the percent of the noise to the image becomes 60%. Vanishing points detection ratio by A.Quattoni and A.Torralbas image DB is over 87%.
A Thrombus Growth Model Based on Level Set Methods
Ma, Chaoqing,Gwun, Oubong THE KOREAN INSTITUTE OF SMART MEDIA 2016 스마트미디어저널 Vol.5 No.1
In this paper, a multi-scale model is applied to the simulation of thrombus growth. This model includes macroscale model and microscale model. The former is used to model the plasma flow with Navier-Stokes equations, and the latter is used to model the platelets adhesion and aggregation, thrombus motion, and the surface expansion of thrombus. The force acting on platelets and thrombus from plasma is modeled by the drag force, and the forces from biochemical reactions are modeled by the adhesion force and the aggregation force. As more platelets are merged into the thrombus, the thrombus surface expands. We proposed a thrombus growth model for simulating the expansion of thrombus surface and tracking the surface by Level Set Methods. We implemented the computational model. The model performs well, and the experimental results show that the shape of thrombus in level set expansion form is similar with the thrombus in clinical test.
Jing Ji,Bing Li,Wenfu Zhang,Yingchun Liu,Chaoqing Yuan,Fei Xing 보안공학연구지원센터 2015 International Journal of Hybrid Information Techno Vol.8 No.1
In order to study the cross-type rigid steel frame node hysteretic behavior of components, the axial compression ratio, H type steel column web thickness, girder section and stiffener as design parameters, 8 steel frame cross-type rigid joints and a T-type rigid joint are designed. Based on simplified mechanical model and constitutive relations of material, using ABAQUS software the corresponding finite element model is established and the hysteretic performance analysis is carried out. Through comparison between given T-type node test results and analysis results, both are in good agreement, thus the rationality of the finite element model established in this paper is verified. Simulation analysis of cross-type node is developed in further, load -displacement hysteretic curve of nodes, skeleton curve, envelope figure and the stress nephogram are extracted and comparative analysis is conducted, influence regularity of four parameters on the seismic behavior of the joints is obtained. The corresponding design suggestion for the axial compression ratio and column web and flange thickness ratio is proposed, design limit value of axial compression ratio of column should be taken as 0.5 and limit value of column web and flange thickness ratio is taken as 0.75,and these can provide reference for actual engineering design.
Chunmei Li,손희정,Chaoqing Huang,로하카레 자이언트,왕명현,이석기 한국식품과학회 2010 Food Science and Biotechnology Vol.19 No.3
Two different species of hawthorn, Crataegus pinnatifida Bunge var. typica Schneider (CBS) and Crataegus pinnatifida Bunge (CB) are traditional medicinal plants,which belong to the Crataegus genus of the Rosaceae family. In this study, the antioxidant, anti-α-glucosidase,and anti-inflammatory activities of CBS and CB methanolic extracts were measured. The CB extract showed significantly higher antioxidant activity than CBS extract by several antioxidants properties. Anti-diabetes activity was expressed as α-glucosidase inhibits activity, both extracts showed very low anti-diabetes activity. Furthermore, the inhibitory activity on lipopolysaccharide (LPS) induced nitric oxide (NO) production and pro-inflammatory iNOS and COX-2mRNA levels were measured. The CBS extract exhibited stronger anti-inflammatory activity than CB extract. Compared the present findings of 2 kinds of Crataegus species, the CB is more suitable for further anti-oxidative research. However, the CBS can potentially be developed into products for the prevention of inflammatory related diseases.
Jing Ji,Zhichao Xu,Liangqin Jiang,Chaoqing Yuan,Yunfeng Zhang,Lijian Zhou,Shilong Zhang 한국강구조학회 2018 International Journal of Steel Structures Vol.18 No.4
This paper was concerned with the nonlinear analysis on the overall stability of H-type honeycombed composite column with rectangular concrete-fi lled steel tube fl anges (STHCC). The nonlinear analysis was performed using ABAQUS, a commercially available fi nite element (FE) program. Nonlinear buckling analysis was carried out by inducing the fi rst buckling mode shape of the hinged column to the model as the initial imperfection with imperfection amplitude value of L /1000 and importing the simplifi ed constitutive model of steel and nonlinear constitutive model of concrete considering hoop eff ect. Close agreement was shown between the experimental results of 17 concrete-fi lled steel tube (CFST) specimens and 4 I-beams with top fl anges of rectangular concrete-fi lled steel tube (CFSFB) specimens conducted by former researchers and the predicted results, verifying the correctness of the method of FE analysis. Then, the FE models of 30 STHCC columns were established to investigate the infl uences of the concrete strength grade, the nominal slenderness ratio, the hoop coeffi cient and the fl ange width on the nonlinear stability capacity of SHTCC column. It was found that the hoop coeffi cient and the nominal slenderness ratio aff ected the nonlinear stability capacity more signifi cantly. Based on the results of parameter analysis, a formula was proposed to predict the nonlinear stability capacity of STHCC column which laid the foundation of the application of STHCC column in practical engineering.
Haomiao Ding,Yuzhe Zhang,Yue Zha,Sijia Zhou,Chaoqing Cao,Huajian Zhu,Feng Xu,Xiuqiang Zhang,Caisheng Wang 한국식품과학회 2022 Food Science and Biotechnology Vol.31 No.13
The cytoprotective and potential molecular mechanisms of Hylocereus polyrhizus protein (RFPP) were investigated on the hydrogen peroxide (H2O2)-triggered damage in normal human embryonic lung (MRC-5) cells. An MTT assay was conducted to assess the MRC-5 cell viability after exposure to H2O2 or RFPP. Cell cycle distribution and apoptosis were explored via flow cytometry. The contents of related proteins were assessed via western blot. MRC-5 cells exhibited markedly decreased cellular viability after treatment with H2O2; however, treatment with RFPP suppressed this decrease. Additionally, RFPP interference dampened H2O2-triggered intracellular apoptosis levels and increased H2O2-triggered intracellular S phase. In these processes, the contents of phosphorylated (p)-AKT along with p-mTOR proteins were downregulated in 120 µM H2O2-treated cells compared with vehicle-treated cells. Nevertheless, in MRC-5 cells inoculated with RFPP, the levels expression of these proteins were reversed. To conclude, RFPP protected MRC-5 cells from H2O2-triggered damage via activation of the PI3K/AKT/mTOR cascade.