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IMPROVING HABITAT OF FORMOSAN LANDLOCKED SALMON BY DAM REMOVAL
Yeh, Chao-Hsien,Lien, Hui-Pang Korea Water Resources Association 2005 Water engineering research Vol.6 No.4
With increasing recognition on conservation of endangered species in Taiwan, one of the major conservation projects is the habitat restoration of Formosan Landlocked Salmon which is major threatened by check dams in the channel for their blockading pathway to upstream and causing the problems of population isolation and close-blood mating. By creating an opening in the central dam body appropriately, partial removal dams can provide pathway for the fish for the better upstream channel habitat. Four check dams at Gau-Shan Creek were remodeled between April of 1999 and September of 2002 with information supported from model experiments under certain hydraulic condition of field environment. Based on the follow-up investigation, the channel morphology of observation sections is in stable condition and the total number of Formosan Landlocked Salmon in this creek increased promptly at the reach containing partial-removed dams.
Value of CT in the Discrimination of Fatal from Non-Fatal Stercoral Colitis
Cheng-Hsien Wu,Chen-Chih Huang,Li-Jen Wang,Yon-Cheong Wong,Chao-Jan Wang,Wan-Chak Lo,Being-Chuan Lin,Yung-Liang Wan,Chuen Hsueh 대한영상의학회 2012 Korean Journal of Radiology Vol.13 No.3
Objective: Clinical presentation and physical signs may be unreliable in the diagnosis of stercoral colitis (SC). This study evaluates the value of computed tomography (CT) in distinguishing fatal from non-fatal SC. Materials and Methods: Ten patients diagnosed as SC were obtained from inter-specialist conferences. Additional 13 patients with suspected SC were identified via the Radiology Information System (RIS). These patients were divided into two groups; fatal and non-fatal SCs. Their CT images are reviewed by two board-certified radiologists blinded to the clinical data and radiographic reports. Results: SC occurred in older patients and displayed no gender predisposition. There was significant correlation between fatal SC and CT findings of dense mucosa (p = 0.017), perfusion defects (p = 0.026), ascites (p = 0.023), or abnormal gas (p = 0.033). The sensitivity, specificity, and accuracy of dense mucosa were 71%, 86%, and 81%, respectively. These figures were 75%, 79%, and 77% for perfusion defects; 75%, 80%, and 78% for ascites; and 50%, 93%, and 78% for abnormal gas, respectively. Each CT sign of mucosal sloughing and pericolonic abscess displayed high specificity of 100% and 93% for diagnosing fatal SC, respectively. However, this did not reach statistical significance in diagnosing fatal SC. Conclusion: CT appears to be valuable in discriminating fatal from non-fatal SC. Objective: Clinical presentation and physical signs may be unreliable in the diagnosis of stercoral colitis (SC). This study evaluates the value of computed tomography (CT) in distinguishing fatal from non-fatal SC. Materials and Methods: Ten patients diagnosed as SC were obtained from inter-specialist conferences. Additional 13 patients with suspected SC were identified via the Radiology Information System (RIS). These patients were divided into two groups; fatal and non-fatal SCs. Their CT images are reviewed by two board-certified radiologists blinded to the clinical data and radiographic reports. Results: SC occurred in older patients and displayed no gender predisposition. There was significant correlation between fatal SC and CT findings of dense mucosa (p = 0.017), perfusion defects (p = 0.026), ascites (p = 0.023), or abnormal gas (p = 0.033). The sensitivity, specificity, and accuracy of dense mucosa were 71%, 86%, and 81%, respectively. These figures were 75%, 79%, and 77% for perfusion defects; 75%, 80%, and 78% for ascites; and 50%, 93%, and 78% for abnormal gas, respectively. Each CT sign of mucosal sloughing and pericolonic abscess displayed high specificity of 100% and 93% for diagnosing fatal SC, respectively. However, this did not reach statistical significance in diagnosing fatal SC. Conclusion: CT appears to be valuable in discriminating fatal from non-fatal SC.
Sustainable Urban Regeneration in Taiwanese Old Urban Districts: From a User's Perspective
Cheng, Hsien-Hsin,Lin, Chao-Chih Sustainable Building Research Center 2010 International journal of sustainable building tech Vol.1 No.1
The researchers intend to approach urban regeneration issues in old urban districts from a user's perspective. Instead of experts' evaluation and professional disciplines, this research relies on the users' perceptions about the factors of the built environment on a liveable urban district. The case study areas are two historic districts in Tainan city - Chihkan district and Minsheng greenpark district. In order to measure the users' attitudes about regeneration issues, the researchers use Likert scale in questionnaire for users to fill in the right scale of their perception. The users to be surveyed can classify into two groups: 1) inhabitants in a district, 2) tourists in a district. As for inhabitants, questionnaire mainly concerns the liveability issues of an old district, for instance, the impact of high density on life quality, or satisfaction about local traffic; whilst for tourists, questionnaire concentrates on cultural tourism issues, for instance, the attractiveness of gourmet, cultural heritage or the degree of importance they feel about the retailing stores, and department stores in old districts etc. After collecting the questionnaires from both two groups, multivariate analysis is used in coding. By factor analysis, the key constructs concerning a liveable district can be concluded with priority order, for instance, cultural heritage as the most important construct, a neighbourhood for all social hierarchy as the second important construct, and a convenient neighbourhood as the third important construct and others. By descriptive statistics, the tourists' attitudes about historic districts can also be summarized, for instance, which element is more appealing to most tourists, or how important do most tourists feel about reused old buildings etc. Research results can be used to build regeneration strategies fit to the need of districts.
The EGF/hnRNP Q1 axis is involved in tumorigenesis via the regulation of cell cycle-related genes
Yu-Chu Wang,Kung-Chao Chang,Bo-Wen Lin,Jenq-Chang Lee,Chien-Hsien Lai,Li-Jyuan Lin,Yun Yen,Chang-Shen Lin,Shiang-Jie Yang,Peng-Chan Lin,Chung-Ta Lee,Liang-Yi Hung 생화학분자생물학회 2018 Experimental and molecular medicine Vol.50 No.-
Heterogeneous nuclear ribonucleoprotein (hnRNP) Q1, an RNA-binding protein, has been implicated in many posttranscriptional processes, including RNA metabolism and mRNA splicing and translation. However, the role of hnRNP Q1 in tumorigenesis remains unclear. We previously performed RNA immunoprecipitation (RIP)-seq analysis to identify hnRNP Q1-interacting mRNAs and found that hnRNP Q1 targets a group of genes that are involved in mitotic regulation, including Aurora-A. Here, we demonstrate that altering the hnRNP Q1 level influences the expression of the Aurora-A protein, but not its mRNA. Stimulation with epidermal growth factor (EGF) enhances both binding between hnRNP Q1 and Aurora-A mRNA as well as the efficacy of the hnRNP Q1-induced translation of Aurora-A mRNA. The EGF/hnRNP Q1-induced translation of Aurora-A mRNA is mediated by the mTOR and ERK pathways. In addition, we show that hnRNP Q1 up-regulates the translation of a group of spindle assembly checkpoint (SAC) genes. hnRNP Q1 overexpression is positively correlated with the levels of Aurora-A and the SAC genes in human colorectal cancer tissues. In summary, our data suggest that hnRNP Q1 plays an important role in regulating the expression of a group of cell cycle-related genes. Therefore, it may contribute to tumorigenesis by up-regulating the translation of these genes in colorectal cancer.