技術變化와 經濟發展

張仁杓 효성여자대학교 산업경영연구소 1987 경영경제 Vol.4 No.-

The object and method of this thesis is to inquire and analyse the Technological change and Economics of Development. The Contents are (1) The Production Function and the ingredient of Technological change, (2) Measurement of Technological change, (3) Embodied Technological change and the Measurement of bias. I Would like to draw a Conclusion about this thesis. Economics of scale can be measured by the complete specification and estimation of production functions at different point in time, or alternatively, through a number of shortcut procedures. If they are carefully done, engineering estimates may constitute a satisfactory shortcut. Our compendium of existing engineering estimates of economies of scale in different industries indicates that many industries may be subject to economics of scale but also that the magnitude of the scale economics tends to vary considerably from industry to industry. The increases in actual plant size that have occurred in most industries may indicate that scale economics increase over time. The study of the changes in the elasticity of substitution has led to two basic conclusions. First, we have found that the elasticity of substitution is generally less than one in industry and probably considerably lower than the elasticity of substitution in agriculture. Second, as more modern technology is adopted, the elasticity of substitution declines. Both findings suggest that as a country develops its ability to substitute labor for capital decreases. If other things would remain equal, this factor alone could be expected to make unemployment a more serious problems as development occurs. Secular changes in technical efficiency have traditionally been measured in terms of disembodied shifts in the constant term of a production function that is restricted in its other parameters. The startling conclusion emerging from such studies has been that an overwhelming proportion of the increase in output (as high as 90 percent in some instances) can be attributed to increases in labor productivity, only the small remainder is due to capital deepening. Such findings imply that the payoff to increases in the rate of investment is relatively small-which does not seem plausible. This shortcoming has led to the formulation of "embcdiment" hypotheses, which admit qualitative changes in the factors of production in the process of development. In the process of formulating embodiment hypotheses, it has been possible to define the bias in technological progress in terms of changes in factor intensity. It is of crucial importance to determine if a certain production process is capital savings or labor saving. Furthermore, changes in factor intensity, combined with changes in the elasticity of substitution between factors, determine changes in factor shares as development occurs and the quantity of output increases. The evidence on these issues is scanty. It would appear that in the United States, at least, technological progress in agriculture has been characterzed by an increase in the capital-labor ratio, which combined with an elasticity of substitution greater than one, has led to a decline in the relative share of labor in agriculture. Our study of the technological parameters of production and of their dynamic properties points to some seeds of trouble that will eventually mature, leading to the conclusion that development may not be as smooth and equilibrating a process as development statics and neoclassical dynamics has generally described it. For example, the existence of economics of scale suggests that neoclassical marginal productivity considerations may be insufficient for explaining the functional distridution of income. Variations in the economics of scale parameter among industries or technologies and over time suggest that some industries may be dominated by large firms and others by small firms. Moreover, if there are different technologies in the same industry, no one of which is dominant in all respects, these differences may explain how large and small firms may coexist. So, too, if the elasticity of substitution decreases either over time or as technology becomes more modern, we would expect that LDCs will have difficulty in absorbing their relatively abundant endowments of unskilled labor. There are still other problems less amenable to explanation on the basis of the traditional paradigm of neoclassical production and growth theory. Productivity changes that have been shown to account for a large portion of the overall growth in output must be intimately related to the process of invention, innovation, and diffusion defies explanation within the neoclassical framework. So does the observed heterogeneity in the world with regard to choice of techniques, scale of operations factor proportions, even prices observed across firms, let alone among industries and countries. A full explanation of technological change and growth must certainly involve more than what the comparative statics or neoclassical dynamics can offer.

白鼠 肝障碍에 對한 補肝湯 瀉肝湯의 效果에 關한 實驗的 硏究

洪茂昌,李學仁,金完熙 慶熙大學校韓醫科大學韓醫學硏究所 1983 慶熙韓醫大論文集 Vol.6 No.-

Para-Chlorophenylalanine이 흰쥐 췌장 외분비부분 샘포세포에 미치는 영향에 대한광학 및 전자현미경적 연구

김인구,정영길,최창도,최월봉 대한해부학회 1994 Anatomy & Cell Biology Vol.27 No.3

보조호르몬요법을 받는 여성 유방암 환자의 모발 변화와 치료 실태에 대한 기초 연구

이재경 ( Jae Kyung Lee ),김창현 ( Chang-hyun Kim ),홍동균 ( Dongkyun Hong ),정경은 ( Kyung Eun Jung ),서영준 ( Young-joon Seo ),김창덕 ( Chang-deok Kim ),이진선 ( Jin Sun Lee ),권인선 ( In Sun Kwon ),박상현 ( Sanghyun Park ),이영 대한피부과학회 2021 대한피부과학회지 Vol.59 No.7

Background: Hormone therapy, which includes tamoxifen and aromatase inhibitors, is the most common adjuvant therapy used for breast cancer. However, only a few studies have reported endocrine therapy induced alopecia. Objective: We investigated the effects of long-term adjuvant hormone therapy on hair in patients with breast cancer, in addition to patients’ concerns and current treatment for hair loss. Methods: Patients completed a questionnaire that included information on self-perceived hair changes after each adjuvant therapy session, distress, and current treatment for hair loss. Using a folliscope, we measured hair density and thickness in each patient and in healthy controls. Results: The study included 93 patients with breast cancer (mean age 51.9±9.8 years). The density and hair thickness were 106.36±21.85 hairs/cm2 and 0.07±0.01 mm in the patient group and 147.86±30.67 hairs/cm2 and 0.07±0.01 mm in the control group (n=98, mean age 52.10±8.40 years), respectively. The mean hair density was significantly lower in the patient group than in the control group; however, no statistically significant intergroup difference was observed in hair thickness. Among 76 patients who perceived hair changes after adjuvant therapy, 71.1% (n=54) were distressed with regard to hair changes. However, only 7.8% of the patients, including two who were treated by dermatologists, currently received treatment for hair changes. Conclusion: Dermatologists should be familiar with hair changes in patients with breast cancer and provide appropriate education to encourage patients to consult dermatologists for hair loss and thinning after breast cancer treatment. (Korean J Dermatol 2021;59(7):521∼526)

Rat의 복강내에 투여한 5-fluorouracil-polyglycolic acid 제형이 장기에 미치는 영향에 관한 연구

강대영,송규상,최정목,노승무,정경수,오정연,김진향,양준묵,최선웅,이진호,조준식,민병무,김용백,김창식,박근성,김승영,김학용,인현빈 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

For more effective intraperitoneal chemotherapy, the authers made 5-fluorouracil-polyglycolic acid composite disks(FU-PGA disks) with 5-fluorouracil and polyglycolic acid, a biodegradable polymer. We inserted the FU-PGA disk into the peritoneal cavites of Sprague-Dawley male rats, the control and three experimental groups; one FU-PGA disk insert group(300mg/kg), two FU-PGA disk insert group(600mg/kg), and three FU-PGA disk insert group(900mg/kg). The control group received a similar number of PGA disk inserts. A pharmacokinetic study was performed to measure the 5-fluorouracil concentration in the peritoneal fluid, blood, and tissues(liver, kidney and heart) at 24 hours, 72hours and 168 hours after insertion of the FU-PGA disk. Light and electron microscopic studies were done. The results were as follows: 1) The number of white blood cells and platelets decreased after FU-PGA insertion. The degree was proportional to the duration and amounts inserted. The change in the number of red blood cells varied slightly. 2) Light microscopically, slight changes were noted at 168 hours in the 3 disk insert group (900mg/kg). Mild fatty change and hepatocyte degeneration around the central veins of the liver were noted, with vacuolar degeneration in the proximal convoluted tubules of the kidney. 3) Electron microscopically,the liver showed focal increases of lipid droplets in the hepatocytes, and irregular nuclear membrane with focal nucleolar segregation of the fibrillar and granular elements. Also the double membranous structure of the hepatocytes and Kupffer cells was widened with bleb formation. The kidney showed wide separation of the nuclear double membrane in the proximal convoluted tubular cells and mesangial cells, with vacuolation and myelin figure formation in the mitochondria of the proximal convoluted tubular cells, at 72 hours and 168 hours in the 2 to 3 FU-PGA insert groups. The heart showed focal loss of cristae,vacuolation and myelin figure formation in the mitochondria of the 2 to 3 FU-PGA insert groups. In conclusion, despite the large amont of FU-PGA inserted, the histopathological changes in the liver, kidney and heart were slight, and consonant with the very low amount of 5-fluorouracil concentrations detected in the liver, kidney and heart. The above results suggest that the FU-PGA composite can serve as a new device for releasing drugs in a controlled manner and easily targeted to intraperitoneal organs. This device can improve the efficacy of intraperitoneal chemotherapy for gastric cancer.

해도분석을 통한 낙동강 하구 사주 면적의 시ㆍ공간 변화

유창일(CHANG-ILL YOO),윤한삼(HAN-SAM YOON),류청로(CHEONG-RO RYU),이인철(IN-CHEOL LEE) 한국해양공학회 2006 韓國海洋工學會誌 Vol.20 No.6

This study discusses characteristic of spatiotemporal changes of the sand barrier in the Nakdong estuarine for the last century, focusing on geomorphologic evolution and mobility of sand barriers in the view of coastal engineering. The Nakdong estuarine, the research subject, has a complexly changing natural environment by interaction between ground and marine elements such as ocean wave, tidal current, sediment, etc. Moreover, recently, unnatural geomorphologic changes (e.g., seaside reclamation, new harbor construction, etc.) has been radically increased in this area with increasing desire for coastal development. Because of this, its sand barrier has developed quite unstable condition. Therefore, to identify the development process of geomorphologic changes in this area, required is a close examination on historical characteristics of spatiotemporal changes of the sand barrier in relation to surrounding seaside reclamation and physical environmental changes. This study, based on the marine charts published in between 1927 and 1995 year, analyzes the length and area of the sand barrier for the last hundred years, and investigates the cause of the changes by looking into the change of water depth for the last two years and doing ocean-physical site observations. In conclusion, the sand barrier of the Nakdong estuarine expands toward the open sea by 7.4~26 m in annual average, maintaining a fixed distance of 1,241~1.279 m, and its area is expected to increase about 2.8 k㎡ annually. This is characterized by the wocean wave from the open sea and the discharge of Nakdong River.

TRANSIENT ISCHEMIA-INDUCED EXPRESSION AND CHANGES OF TYROSINE KINASE A IN THE HIPPOCAMPAL DENTATE GYRUS OF THE GERBIL

HWANG, IN,LEE, HYEON,YOO, KI-YEON,KIM, DAE,KIM, JUNG,KIM, CHANG,LIM, BEONG,KANG, TAE-CHEON,BANG, KYUNG,SEONG, NAK,LEE, HAK,KIM, JONG,WON, MOO Taylor Francis 2006 International journal of neuroscience Vol.116 No.8

<P>The present study examined ischemia-related changes in tyrosine kinase A (trkA) immunoreactivity and its protein content in the dentate gyrus after 5 min of transient forebrain ischemia in gerbils. One day after ischemic insult, cresyl violet-positive polymorphic cells showed ischemic degeneration. The ischemia-induced changes in trkA immunoreactivity were found in the polymorphic layer (PL) and granule cell layer (GCL) of the dentate gyrus. In the sham-operated group, trkA immunoreactivity in the dentate gyrus was very weak. From 30 min after ischemia, trkA immunoreactivity was increased in the dentate gyrus and peaked in the dentate gyrus at 12 h after ischemia-reperfusion. Thereafter, trkA immunoreactivity was decreased time-dependently after ischemia-reperfusion. Four days after ischemic insult, trkA immunoreactivity was similar to that of the sham-operated group. In addition, it was found that ischemia-related changes in trkA protein content were similar to the immunohistochemical changes. These results suggest that the chronological changes of trkA in the dentate gyrus after transient forebrain ischemia may be associated with ischemic damage in polymorphic cells of the dentate gyrus.</P>

한국사회에서의 도서와 육지간의 접합에 관한 연구 : 제주도의 경우 A Case of Cheju Island

유철인,고남욱,고창훈 제주대학교 1986 논문집 Vol.16 No.1

Recent introduction of citrus cultivation causes the growth of Cheju regional economy with the inflow of external captial under the influnce of external market. These processes result in the Cheju regional economy dependent upon the national economy. Since the advent of large-scale tourism often necessitates the transfer of local control to a central government, Cheju society as a touristic place is more dependent on national society with the national development projects on Cheju island. These tourism and citrus cultivation cause rapid urbanization, more access to education, more exposure to mass communication, and the increase in the mobility of both of Cheju islander and mainlander, As a result, Cheju culture becomes more assimilated into mainland or national culture. We call these recent phenomana the social articulation between Cheju island and mainland as a larger society. The term articulation is the congruence or working together of differrent strata or different levels such as the articulation of modes of producction. Paticularly, as used in this paper, it describes the process by which the local island society becomas in corporated more fully into the larger society. This paper examines (1) the phenomena social articulation between Cheju island and mainland in terms of regional economy and policies, (2) the response of community to this articulation, and (3) its impacts on the development of Cheju island and the prospects of desirable relationship between local island society and the center. First of all, Cheju industry structure consists of 34.9% in the primary, .3% in the secondary, and 60.8% in the itertiary industry,in terms of vaules added as of 1981, while in 1971 the primary industry dominant. Employments by industry In Cheju region as of 1981 consist of 71.7% in the primary, 3.2% in the secondary, and 25.1% in the tertiary industry. Cheju regional economy is articulated with national economy because of citrus cultivation and products of fishery under influendces of domestic and foreign markets as well as a tourism industry as a leading industry for regional development. People in Cheju island feel the state of alination with these overwhelming changes, which is followed by outsider's speculation on land, the leakage of benefits resulted from outside capital investment, and the evnvironmental pollution. These phenomena may be discovered in the transformation from the closed socioeconomic system to the open socioeconomic system. Seocond, the articulating process of structual dependency of political, economic, and social fields is reavealed concretely in the process of formulation, making, and implementation of polities. The philosopical foundation of policy is not the philosophy of Small-is-beautiful, but the philosophy of Big-is-good. And the goal of policy is sought out without conscideration of the basic problems such as openess and closedness, national-oriented and international-oriented development and conservation, and active participation and passive alination of islanders. We learn that the formulation, content, and implemantation by national elites affected by not the volition of residents in Cheju-Do, but the vested interest of large firms and international capital investment. Its effects are expressed in terms of the alination, the powerlessness, and the suffering of Cheju islanders. Third, under the vast process of acculturation, these overwhelming waves of change do stimulate the Cheju society as a so-called periphery in acquiring a consciousness of the degree of exploitation it is subjected to. As an adaptive action, Cheju cultural identity is maintained and/or invented with the emphasis on its own traditional spirits, which may be considered as the revitalization movements in Cheju culture. Ambivalance toward mainland as an outer world is expressed in everyday life in Cheju society. Ambivalance toward an outer world is thought to be discovered in any society articulated with and dependent upon the lager society. Cheju islanders also miss tat Cheju culture becomes more assimilated into mainland or national culture. We consider the social articulation of Cheju island and mainland amid historical context of the contacts with mainland as sociocultural forces which operate to create Cheju cultural identity. The aura of Cheju cultural identity and traditionalism is one of the devices which insures the continuance of boundaries between Cheju islander and non-islander (mainlander) within a tourism and the migration of mainlanders, Cheju islanders' perception of what mainlanders think about Cheju islanders operates to create the meaning and content of their cultural identity is maintained may consist of the contacts with mainlandsers and the formation of an image on them. We concluded that the articulation must be transformed from total dependency into the equity through the structual autonomy, changes in policies, and cultural autonomy This means the balance of everyday ilife in an island and a mainland, and further, in the center and peripheries. Alternatives for this desirable articulation are as follows. First of all, the decentralized and autonomous political-administrative structure, the active and intensive regional economy, and social cultural development focused on community must become to be interrelated in order to be an intergrated development from within. Secondly, the development policies must be fundamentally changed in terms of basic philosophy, content, and implempentation. Lastly, the cultural diversity is to be fully appreciated, based on the understanding of local cultures or subcultures.

조직변화 유형과 Appreciative Inquiry(AI) 기반 조직변화모델에 관한 연구

장석인 ( Sug-in Chang ) KNU기업경영연구소 2021 기업경영리뷰 Vol.12 No.3

오늘날의 기업경영환경은 과거보다 지식이나 기술 등의 급속한 변화에 따라 많은 도전에 직면하고 있다. 많은 기업이 조직의 효율 극대화를 가능하게 하는 조직구조로써 팀제를 선택하고 있다. 기존의 도구나 방법으로는 해결하기 어려운 상황과 변화 때문에 영향을 받는 21세기 조직의 경우 결함 기반의 모델(model based on deficit)은 산업화 시대에 주로 사용된 조직개발 방법으로써 적합하지 않다. 이에 대한 대안으로 오늘날 기업은 긍정적 탐색 혹은 긍정 혁명이라 불리는 강점기반(Appreciative Inquiry: AI) 의 조직변화 모델에 주목하고 있다. 강점기반 조직변화 모델(Organizational Change Model based on Appreciative Inquiry)은 현재조직를 개선하고 미래의 비전을 구상하기 위한 수단으로서 조직구성원에게 조직 내에서 가장 좋았던 경험, 성공 이야기, 그리고 긍정적인 성과 등을 생각나게 하는 질문을 제시하는 접근방식이다. 본 연구는 조직변화와 강점기반 조직변화 모델(Organizational Change Model based on Appreciative Inquiry) 을 탐구하는 데 목적이 있다. 이러한 연구의 목적을 달성하기 위해 첫째, 조직변화 유형과 조직변화모델을 고찰하고자 한다. 둘째, 강점기반 모델(Appreciative Inquiry Model)의 원리와 프로세스에 대한 살펴보고, 마지막으로 연구 결과와 시사점을 도출하고자 한다. Today’s business environment faces many challenges due to rapid changes in knowledge and technology than in the past. Many companies are choosing the team system as an organizational structure that enables maximiza-tion of organizational efficiency. For organizations in the 21st century that are affected by changes and situations that are difficult to solve with existing tools or methods, the model based on deficit is not suitable as an organiza-tion development method mainly used in the industrialization era. As an alternative to this, today’s companies are paying attention to the organizational change model of Ap-preciative Inquiry (AI) called positive search or positive revolution. Organizational Change Model based on Ap-preciative Inquiry is a means to improve the present organization and envision a future vision. This model is an approach that asks members of the organization questions that remind them of their best experiences within the organization, success stories, and positive outcomes. The purpose of this study is to explore organizational change and the Organizational Change Model based on Appreciative Inquiry. In order to achieve the purpose of this study, first, the types of organizational change and organizational change models are to be investigated. Second, the principle and process of the Appreciative In-quiry Model will be reviewed, and finally, research results and implications will be drawn.

Ⅲ급 부정교합자의 양악 수술과 하악 편악 수술 시 연조직 변화에 관한 비교 연구

박영국,장인희,이영준 대한치과교정학회 2006 대한치과교정학회지 Vol.36 No.1

악교정 수술 시행 시 연조직 변화에 대한 대부분의 연구는 Ⅱ급 부정교합을 대상으로 하였다. 또한 수술 방법에 따른 연조직 변화에 대한 비교 연구가 부족하였다. 따라서 이 연구는 골격성 Ⅲ급 부정교합자에서 상악골 전진술과 하악골 후퇴술을 동시에 시행한 양악 수술과 하악골 편악 수술 시행 시, 경조직과 연조직 측모 및 연조직 두께의 변화를 관찰하고, 수술 전후 변화의 상관성을 산출하며, 경조직 변화에 수반하는 연조직 변화의 비율을 산출하여 교정-악교정 수술 복합 치료 계획 수립과 결과의 예측에 이용하고자 시행되었다. 경희대학교 치과병원 교정과에 내원하여 골격성 Ⅲ급 부정교합자로 진단받은 환자 52명을 대상으로 하여, Le Fort I osteotomy를 이용한 상악골 전방이동술과 시상분할골절단술을 이용한 하악골 후퇴술을 시행한 양악 수술군 26명과 하악골 후퇴술만을 시행한 편악 수술군 26명으로 구분하여, 수술 전후 측모두부방사선규격사진을 계측, 분석하여 다음과 같은 결과를 얻었다. 양악 수술군은 골격 변화량의 72.4% 비율로 상순 부위 연조직의 전방 이동을 보였으며, 편악 수술군은 통계적으로 유의한 변화를 보이지 않았다. 비순각은 양악 수술군에서 편약 수술군에 비해 더 크게 증가하였다. 이순각은 편악수술군에서 더 크게 감소하였다. 하악골의 후방 이동에 따른 연조직 pogonion의 후방 이동은 양악 수술군에서 98%, 편악 수술군에서 109%로 편악 수술군에서 더 크게 나타났다. 양악 수술군에서는 편악 수술군에 비하여 경조직의 변화에 수반하는 상순에서의 큰 변화가 나타났다. 편악 수술군에서는 상순의 변화는 미약하엿으며, 하순 및 이부의 변화가 양악 수술군에 비해 두드러지게 나타났다. Numbers of postulations lie on the difference of integumental changes with two major surgical remedies of one jaw vs. two jaw surgery in skeletal Class Ⅲ malocclusion. Accordingly it was the aim of the study to elucidate the skeletal profile changes with an accompanying disposition of soft tissues, consequently to yield the correlation and ratio of soft tissue changes with two types of surgical procedures, which in turn make it possible to predict the soft tissue outcomes by means of assembled regression equations. Cephalometric headfilms of fifry two adult skeletal Class Ⅲ comprised of 26 maxillary advancement by Le Fort I osteotomy and mandibular setback by sagittal split ramus osteotomy simultaneously (double jaw surgery, group A), 26 mandibular setback alone (one jaw surgery, group B) were statistically analyzed. Group A manifested 72.4% soft tissue advancement to skeletal changes in the upper lip area, while group B appeared to have no statistically significant changes. The nasolabial angle showed more increment in group A than in group B, whereas the mentolabial angle illustrated more reduction in group B. The backward movement of soft tissue pogonion to skeletal change revealed 98% in group A, and 109% in group B. The double jaw surgery group characteristically revealed remarkable integ umental change in the upper lip area, while the one jaw surgery had major effects in the lower lip and soft tissue pogonion areas.