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EXCHANGE RATE EXPOSURE AND STOCK BETAS
Vinod Chandrashekaran 사람과세계경영학회 1999 Global Business and Finance Review Vol.4 No.1
In this paper, I examine the impact of foreign exposure of a company on the systematic and total risk of a company. The systematic risk of a company is measured as the sensitivity of the company[s stock with respect to the home-country market (in this paper, the U.S. market) and total risk is measured as the standard deviation of the return on the stock. If the beta of a company's foreign operations with respect to the foreign market is high and/or the foreign market has high correlation with the U.S. market and/or the foreign market has high volatility relative to the U.S. market, the systematic and total risk of a company with foreign market operations may, theoretically at least, be higher than an identical company with no foreign operations. The existence and extent of risk reduction due to the presence of foreign operations is, therefore, an empirical question. In this study, I examine these issues empirically. My results indicate that foreign market exposure did not Lead to significant decreases in beta over the period 1973-97.
Impaired liver regeneration and lipid homeostasis in CCl4 treated WDR13 deficient mice
Arun Prakash Mishra,Archana B. Siva,Chandrashekaran Gurunathan,Y. Komala,B. Jyothi Lakshmi 한국실험동물학회 2020 Laboratory Animal Research Vol.36 No.4
WDR13 - a WD repeat protein, is abundant in pancreas, liver, ovary and testis. Absence of this protein in mice has been seen to be associated with pancreatic β-cell proliferation, hyperinsulinemia and age dependent mild obesity. Previously, we have reported that the absence of WDR13 in diabetic Leprdb/db mice helps in amelioration of fatty liver phenotype along with diabetes and systemic inflammation. This intrigued us to study direct liver injury and hepatic regeneration in Wdr13−/0 mice using hepatotoxin CCl4. In the present study we report slower hepatic regeneration in Wdr13−/0 mice as compared to their wild type littermates after CCl4 administration. Interestingly, during the regeneration phase, hepatic hypertriglyceridemia was observed in Wdr13−/0 mice. Further analyses revealed an upregulation of PPAR pathway in the liver of CCl4- administered Wdr13−/0 mice, causing de novo lipogenesis. The slower hepatic regeneration observed in CCl4 administered Wdr13−/0 mice, may be linked to liver hypertriglyceridemia because of activation of PPAR pathway.
Development of a Robust Polyvoltine Breed $'NP_1'$ of the Mulberry Silkworm, Bombyx mori L.
Singh Ravindra,Rao D. Raghavendra,Sharma S.D.,Chandrashekaran K.,Basavaraja H.K.,Kariappa B.K.,Dandin S.B. Korean Society of Sericultural Science 2006 International Journal of Industrial Entomology Vol.12 No.1
A breeding programme was initiated during 2001 utilizing two polyvoltine silkworm breeds viz. $BL_{69}$, an evolved breed tolerant to high temperature and MAR, comparatively resistant to Bombyx mori nuclear polyhedrosis virus (BmNPV) with the objective to develop robust polyvoltine breeds and hybrids. The breed $NP_1$ was developed by exposing the fifth instar larvae to high temperature $(36{\pm}1^{\circ}C)$, high Relative Humidity ($85{\pm}5%$ R.H.) and inoculating third instar larvae with BmNPV inoculum. At $F_{12}$, the breed was tested for hybrid forming ability utilizing six bivoltine silkworm breeds viz. $CSR_2,\;CSR_4,\;CSR_{17},\;CSR_{18},\;CSR_{19}\;and\;NB_4D_2$. The hybrid $'NP_1{\times}CSR_{17}'$ exhibited its superiority by recording 97.2% survival, 1.892 g cocoon weight, 0.406 g cocoon shell weight, 21.5% cocoon shell ratio, 16.6% raw silk percentage and 890 m filament length whereas the control $(PM{\times}CSR_2)$ has recorded 90.2% survival, 1.599 g cocoon weight, 0.304 g cocoon shell weight, 18.9% cocoon shell ratio, 13.1 % raw silk percentage and 768 m filament length. Commercial exploitation of the new $polyvoltine{\times}bivoltine$ hybrid in sericulture industry has been discussed.