http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
A comprehensive review of the mental spine
Ross Champagne,Rithvik Vutukuri,Chung Yoh Kim,R. Shane Tubbs,Joe Iwanaga 대한해부학회 2024 Anatomy & Cell Biology Vol.57 No.1
Clinical case reports and research regarding the mental spines and their associated structures create a detailedpicture of the f loor of the mouth for assessment during clinical treatment. This compilation of information covers themental spines, the attached geniohyoid and genioglossus muscles, the lingual foramina, and the veins and arteries of the jawand f loor of the mouth. It is important to consider the variations in the mental spines for oral and maxillofacial treatmentinvolving the mandible. Differences in anatomy of the mental spine, including their number, location, and size, can impactdiagnosis and treatment approaches
Sagittal Balance Correction Following Lumbar Interbody Fusion: A Comparison of the Three Approaches
Pierre-Olivier Champagne,Camille Walsh,Jocelyne Diabira,Marie-Élaine Plante,Zhi Wang,Ghassan Boubez,Daniel Shedid 대한척추외과학회 2019 Asian Spine Journal Vol.13 No.3
Study Design: Retrospective cohort study. Purpose: The objective of this study was to compare three widely used interbody fusion approaches in regard to their ability to correct sagittal balance, including pelvic parameters. Overview of Literature: Restoration of sagittal balance in lumbar spine surgery is associated with better postoperative outcomes. Various interbody fusion techniques can help to correct sagittal balance, with no clear consensus on which technique offers the best correction. Methods: The charts and imaging of patients who have undergone surgery through either open transforaminal lumbar interbody fusion (TLIF), minimally invasive TLIF (MIS TLIF), or oblique lumbar interbody fusion (OLIF) were retrospectively reviewed. The following sagittal balance parameters were measured pre- and postoperatively: segmental lordosis, lumbar lordosis, disk height, pelvic tilt, and pelvic incidence. Data on postoperative complications were gathered. Results: Only OLIF managed to significantly improve segmental lordosis (4.4°, p<0.001) and lumbar lordosis (4.8°, p=0.049). All approaches significantly augmented disk height, with OLIF having the greatest effect (3.7°, p<0.001). No approaches were shown to significantly correct pelvic tilt. Pelvic incidence remained unchanged in all approaches. Open TLIF was the only approach with a higher rate of postoperative complications (33%, p=0.009). Conclusions: The OLIF approach might offer greater correction of sagittal balance over open and MIS TLIF, mainly in regard to segmental lordosis, lumbar lordosis, and disk height. MIS TLIF, although offering more limited access than open TLIF, was not inferior to open TLIF in regard to sagittal balance correction. A higher rate of complications was shown for open TLIF than the other approaches, possibly due to its more invasive nature.
Searching for Resonances in the Unbound 6Be Nucleus by Using a Radioactive 7Be Beam
채경육,D. W. Bardayan,J. C. Blackmon,M. S. Smith,A. E. Champagne,J. J. Das,R. P. Fitzgerald,D. W. Visser,V. Guimaraes,K. L. Jones,S. D. Pain,J. S. Thomas,M. S. Johnson,R. L. Kozub,R. J. Livesay,Z. Ma,C. 한국물리학회 2012 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.61 No.11
Knowledge of the <sup>3</sup>He(<sup>3</sup>He,<sup>2</sup><i>p</i>)<sup>4</sup>He reaction is important for understanding stellar burning and solar neutrino production. Previous measurements have found a surprisingly large rise in the cross section at low energies that could be due to a low-energy resonance in the <sup>3</sup>He + <sup>3</sup>He (<sup>6</sup>Be) system or electron screening. In the <sup>6</sup>Be nucleus, however, no excited states have been observed above the first 2<sup>+</sup> state at <i>E<sub>x</sub></i> = 1.67 MeV up to 23 MeV, even though several are expected. The <sup>2</sup>H(<sup>7</sup>Be,<sup>3</sup>H)<sup>6</sup>Be reaction has been studied for the first time to search for resonances in the <sup>6</sup>Be nucleus that may affect our understanding of the <sup>3</sup>He(<sup>3</sup>He,<sup>2</sup><i>p,</i>)<sup>4</sup>He reaction. A 100-MeV radioactive <sup>7</sup>Be beam from the Holifield Radioactive Ion Beam Facility (HRIBF) was used to bombard CD<sub>2</sub> targets, and tritons were detected by using the silicon detector array (SIDAR). A combination of reaction mechanisms appears to be necessary to explain the observed triton energy spectrum.
Development of Cr cold spray – coated fuel cladding with enhanced accident tolerance
Martin Seve cek,Anil Gurgen,Arunkumar Seshadri,Yifeng Che,Malik Wagih,Bren Phillips,Victor Champagne,Koroush Shirvan 한국원자력학회 2018 Nuclear Engineering and Technology Vol.50 No.2
Accident-tolerant fuels (ATFs) are currently of high interest to researchers in the nuclear industry and ingovernmental and international organizations. One widely studied accident-tolerant fuel concept ismultilayer cladding (also known as coated cladding). This concept is based on a traditional Zr-based alloy(Zircaloy-4, M5, E110, ZIRLO etc.) serving as a substrate. Different protective materials are applied to thesubstrate surface by various techniques, thus enhancing the accident tolerance of the fuel. This studyfocuses on the results of testing of Zircaloy-4 coated with pure chromium metal using the cold spray (CS)technique. In comparison with other deposition methods, e.g., Physical vapor deposition (PVD), lasercoating, or Chemical vapor deposition techniques (CVD), the CS technique is more cost efficient due tolower energy consumption and high deposition rates, making it more suitable for industry-scale production. The Cr-coated samples were tested at different conditions (500 C steam, 1200 C steam, andPressurized water reactor (PWR) pressurization test) and were precharacterized and postcharacterizedby various techniques, such as scanning electron microscopy, Energy-dispersive X-ray spectroscopy(EDX), or nanoindentation; results are discussed. Results of the steady-state fuel performance simulationsusing the Bison code predicted the concept's feasibility. It is concluded that CS Cr coating has highpotential benefits but requires further optimization and out-of-pile and in-pile testing
RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination
Matthews, Adam G. W.,Kuo, Alex J.,Ramó,n-Maiques, Santiago,Han, Sunmi,Champagne, Karen S.,Ivanov, Dmitri,Gallardo, Mercedes,Carney, Dylan,Cheung, Peggie,Ciccone, David N.,Walter, Kay L.,Utz, Pau Nature Publishing Group 2007 Nature Vol.450 No.7172
Nuclear processes such as transcription, DNA replication and recombination are dynamically regulated by chromatin structure. Eukaryotic transcription is known to be regulated by chromatin-associated proteins containing conserved protein domains that specifically recognize distinct covalent post-translational modifications on histones. However, it has been unclear whether similar mechanisms are involved in mammalian DNA recombination. Here we show that RAG2—an essential component of the RAG1/2 V(D)J recombinase, which mediates antigen-receptor gene assembly—contains a plant homeodomain (PHD) finger that specifically recognizes histone H3 trimethylated at lysine 4 (H3K4me3). The high-resolution crystal structure of the mouse RAG2 PHD finger bound to H3K4me3 reveals the molecular basis of H3K4me3-recognition by RAG2. Mutations that abrogate RAG2’s recognition of H3K4me3 severely impair V(D)J recombination in vivo. Reducing the level of H3K4me3 similarly leads to a decrease in V(D)J recombination in vivo. Notably, a conserved tryptophan residue (W453) that constitutes a key structural component of the K4me3-binding surface and is essential for RAG2’s recognition of H3K4me3 is mutated in patients with immunodeficiency syndromes. Together, our results identify a new function for histone methylation in mammalian DNA recombination. Furthermore, our results provide the first evidence indicating that disrupting the read-out of histone modifications can cause an inherited human disease.