내피세포 Nitric Oxide 유리를 통한 산사의 혈관이완 작용

채종구,김길훤,신흥묵 대한동의생리학회,대한동의병리학회 2003 동의생리병리학회지 Vol.17 No.1

It had been known for a while that Crataegi Fructus(CF; Crataegus pinnatifida Bunge) had only a digestive effect. Recently, it has been demonstrated that CF also has an ant-hypertensive effect. However, its mechanism of relaxant effect has not been investigated yet This study was examined to investigate the mechanism of vascular relaxation effect of CF in isolated rat thoracic aorta. CF revealed significant relaxation to phenylephrine(PE)-induced arterial contraction but much less to KCI-induced one. When CF was pretreated, it inhibited PE-induced contraction non-competitively. Methylene blue(10^(-6)M) completely blocked the relaxant effect of CF whereas L-NAME(10^(-5)M) did almost completely. However, atropine(10^(-6)M) did not have any influence on vascular relaxation effect of CF. Regarding cNOS activity, CF significantly increased its activity from rat whole brain homogenate in a dose dependent manner which was inhibited by L-NAME(10^(-5)M). On the other hand, CF did not affect on expression of TNF-α mRNA in RAW 264.7 calls, suggesting that CF is not related to iNOS activity. These results indicate that CF would be effective in relaxing vascular contraction through release of endothelial nitric oxide.

초등학교에서 에너지의 합리적 사용을 위한 STS 프로그램의 개발과 적용 효과

최상길,김채복,최준섭 韓國實科敎育硏究學會 2002 實科敎育硏究 Vol.8 No.1

The purpose of this study was to develop STS teaching-learning program which focuses on real-life experiences for reasonable energy usage, and to verify how STS teaching-learning program affects the understanding knowledge concerned energy and the attitude towards saving energy. The subjects of this study were students of the 6th grade at an elementary school in Kyong-Ju. They were divided into two groups, an experimental group and a control roup. The developed STS teaching-learning program had been applied to the experimental group. However, the traditional teaching-learning process had been employed to the control group for four weeks. The main results of this study are as follows : (1) The developed STS teaching-learning program consists of following subjects ; energy resources, growing energy consumption, heat-energy transfer, energy and environment, saving energy, efficient usage of electricity and opening ‘ANABADA’ market. (2) In the understanding of knowledge concerned energy, there was no difference between the experimental group and control group. (3) In the attitude toward saving energy, there was a considerable significant difference between he experimental group and control group. However, there was no difference between male and female students, respectively.

버스안내시스템 구축을 위한 도착시간예측 알고리즘 개발

임채문,김은길,공창환,이영우 대구대학교 과학기술연구소 2001 科學技術硏究 Vol.8 No.2

This study proposed the algorithm on the estimation time of bus arrival time, using queue lengths, rules for running traffic signal and GPS position datum. The estimated values by means of proposal algorithms were done by the statistical application test. In this study, queue lengths and vehicle discharge properties based on the video photograph had been surveyed in three traffic signal intersection. The surveyed datum were analyzed that discharge headway times from one to three were about 2.5 seconds. the others were about 1.8 seconds. The datum for investigation and the calculation values by means of proposal algorithms revealed that the results based on the t-test are statistically significant.

가입자 전송장비의 특성 비교를 통한 N * 64K 회선의 품질 향상에 관한 연구

이채욱,길명환 大邱大學校 科學技術硏究所 1998 科學技術硏究 Vol.5 No.2

Subscriber network is interfaced to network user directly and very profitable to the communication company. The study of user- network is very important because of its large portions of total equipments. It takes a long time to realize FTTH(fiber to the home) generalization. Therefore using HDSL(high bit rate digital subscriber line) and FDSU(flexible data service unit), we can make effective wide bandwidth method of user network. In this paper, connection equipments that HSM, HDSL and FDSU are applied from 128Kbps to 768kbps. Characteristics of transmission line that transmission velocity, error and distance are analyzed by experiments. The analysis of this results is useful to N x 64Kbps equality promotion.

소아정신과 환자의 임상적 고찰 : 부산의 한 사립종합병원의 외래 및 입원환자의 경험

이채일,김정기,김종길 大韓神經精神醫學會 1985 신경정신의학 Vol.24 No.3

1978년 1월 1일부터 1983년 12월 31일까지 만 7년간 본원 신경정신과 외래를 방문하였던 소아환자 986명, 입원환자 76명을 대상으로 하여 다음과 같은 결과를 얻었다. 1. 신경정신과 외래 총 신환자 9326명중 소아환자는 986명으로 10.57%를 차지하였다. 입원환자의 경우 총 2,247명중 소아환자는 76명으로 3.36%였다. 2. 형제순위는 맏이가 37.59%로 가장 많았고 다음으로 중간과 막내가 각각 28.71%였다. 3. 발병후 내원시 까지의 기간은 6개월이상이 41.48%로 가장 많았고 1주이내 19.22%, 2개월에서 6개월이 17.35%의 순서였다. 4. 동반보호자의 어머니가 74.21%로 가장 많았고 부모 9.21%, 아버지 8.76%, 형제 3.04%의 순서였다. 5. 주소는 두통 19.59%, 신체증상 17.89%, 경련 9.25%, 수면장애 8.03%의 순서였다. 6. 진단은 외래의 경우 신경증 30.08%, 특수증상군 16.67%, 간질 12.89%, 정신지체 5.80%의 순서였으며 입원환자의 경우 신경증 53.32%, 일과성 상황장애 9.21%, 간질 14.47%, 정신분열증 10.53%의 순서였다. 7. 치료에 대한 반응은 투약하에 관찰한 경우가 73.36%였는데 투약없이 관찰만 한 경우보다 병원을 방문한 횟수가 유의있게 많았다. Clinical study was done for the children who visited Department of Neuropsychiatry, Maryknoll Hospital, Pusan, Korea, from Jan. 1, 1978 to Dec. 31, 1983. The results were as follows: 1. The first visiting childhood outpatients occupied 10.57% of all the first visiting psychiatric outpatients, and 3.31% of all the psychiatric inpatients were children. 2. Viewing the sibling order of the outpatients, the eldests were 35.59% of them, and the middles and the youngests were 28.71% respectively. 3. Most of the first visiting outpatients(41.48%) came to the hospital more than 6 months after onset. 4. The frequent chief complaints for which the first visiting outpatients sought medical help were headache, followed by somatic symptoms, convulsions, sleep disturbances, bizarre behaviours, in order. 5. Almost all the patients were accompanied by their mothers. 6. Among the outpatients, the most frequently encountered disease entity was neurosis, and then special symptoms, epilepsy, mental retardation, in order of frequency. Among the inpatients, the diagnosis of neurosis was also the most frequent one, followed by transient situational disturbances, epilepsy, schizophrenia, in order. 7. The number of visiting the outpatient clinc was greater in the patients whose medication were prescribed, compared with the patients whose medication were not prescribed.

국악감상수업을 위한 멀티미디어 학습자료개발 : 초등학교 3, 4학년을 중심으로

김동현,채길룡,오한숙 光州敎育大學校 初等敎育硏究所 2002 初等敎育硏究 Vol.17 No.-

Emphasis of Korean classical music has been greatly placed on the music course since the 6th curriculum, and it is more laid in the 7th curriculum; the content is more detailed and Korean classical music of materials in music textbook amounts to 38% - increased 10% compared to the 6th curriculum. Now is rather to devise data to enable 'esthetical experience' of Korean classical music by providing certain 'experience activity' program and develop data to be effectively used in the field than to discuss weight of Korean classical music education. Therefore, this study attempts to develop appreciation data with computer and multimedia to be used as teaching and learning data in the appreciation area, which specially teachers suffer from how to guide, among several areas of Korean classical music. For such objective, the music course of the third and fourth grader was analyzed to draw a teaching and learning objective and a viewpoint of appreciation, materials of Korean classical music were examined in textbook, and various multimedia data and related website to improve teaching effect were surveyed, arranged and made into PowerPoint data. In addition, students' interest in learning and results of the performance evaluation were compared by application of the produced multimedia data to the actual field class to verify effect of data use. As a result of comparison of results of students' interest in Korean classical music appreciation class before and after application of the produced data, use of the data influenced improvement of students' interest in Korean classical music class. Also, as a result of making the field teachers who are interested in Korean classical music class examine the data, they responded that the data is very useful for improvement of the field Korean classical music class. Results of this study are summarized as follows; A. In Korean classical music class, data enabling broad experience and musical practice through application of the varied multimedia dta out of monotonous listening-centered class was developed. B. Out of the limited educational environment by improvement of teaching and learning method with ICT, self-directional learning was enabled in consideration of learner's level and interest.

대도시 男女 靑少年의 身體發育에 관한 硏究 : Using longitudial data concerning student aged 7-16 7세에서 16세까지의 종단적 자료를 이용하여

채길연,김 명 韓國保健敎育學會 1989 보건교육건강증진학회지 Vol.6 No.1

This study tries to show the physical growth patterns and various adolescent characteristics by using longitudinal data for the height, weight, chest girth and sitting height of 1,132 high school students in Seoul. And this study also tries to show what influencing factors on the physical growth of this aged population. The followings are the results. 1. The boys have their peak velocity of height when they are 12~13 years old. And the girls have when they are 10∼11 years old. Peak velocity of weight for boys is at the age of 13∼14. And for girls is at the age of 11∼12. Peak velocity of chest girth for boys is at the age of 12∼ 13. And for girls is at the age of 11∼12. Peak velocity of sitting height for boys is at the age of 13∼14. And for girls is at the age of 11~13. So girls of this period grow more rapidly by around two years than boys. 2. The menarche of girls begins at the age of 12.4. So it begins 1.4 year before peak height velocity period. 3. Of life behavior boys contingency coefficient between essential time and height and weight is .5150. and .4795. that between studying time and height and weight is .3344 and and .2912(In case of girls is .4735, .4321, .3247, .3134).

한국 핸드볼 경기의 내용분석과 미래방향 : Content Analysis and Future Directions

박천조,백상서,채병준,안길영 한국스포츠리서치 2003 한국 스포츠 리서치 Vol.20 No.1

This study is to investigate the researches with handball game by research domain and methodological aspects during its 10years (1990-2000). As results of analyzing methodological structure, characteristics of subjects by research domain and the number of articles statistical techinics by years. 1. the researches of handball games need longitudinal study with academic arena in accordance with the globalization trends. 2. The number of case and representative is to provide academic suport therefore it is nesessary to provide effect size for handball games for identify susficious questions sample sizes for students and professors in the field of measurement & evaluation 3. It is proud to acculately need to test methodological research domains in order for performing handball related researches journal to be acknowledged by scholars in other parts of the world. the focus must be on equality rather than on quantity.

모래다짐말뚝의 원심모델링

유남재,정길수,김상진,채승호 江原大學校 産業技術硏究所 2001 産業技術硏究 Vol.21 No.B

This paper is results of extensive centrifuge model experiments about design factors influencing the bearing capacity and the settlement behaviors of SCP (Sand Compaction Pile). Centrifuge model tests were carried out changing design factors for SCP method such as replacement area ratio (as= 20, 40, 70%), improvement ratio to footing width (W/B = 1, 2, 3), and amount of fines in sand pile (#200 = 5, 10, 15). Therefore, the effects of these design factors on the bearing capacity and the settlement behavior of SCP were investigated and changes of stress concentratio rato due to such an design factors were also investigated. Centrifuge model testing technique for preparing and installing centrifuge model of sand compaction pile, using freezing them, was also developed. As results of centrifuge model tests, more fines in sand compaction pile increases the bearing capacity of SCP. Optimum improvement ratio to footing width was found to be 2. Values of stress concentration ratio was in the ranges of 1.5 - 3.5. The depth of bulging in sand piles was found in the range of 2.0 - 2.5 times of pile diameter.

퉁퉁마디로부터 염에 의하여 유도되는 Aldolase 유전자의 분리 및 발현분석

차준영,네티 엘마와티,김순길,이증주,임채오,정우식,이곤호,손대영 Plant molecular biology and biotechnology research 2003 Plant molecular biology and biotechnology research Vol.2003 No.-

Soil salinity is one of the most serious abiotic stresses limiting the productivity of agricultural crops. To cope with salt stress, plants respond with physiological, developmental and biochemical changes, including the synthesis of a number of proteins and the induction of gene expression. Salicornia herbacea is a halophytic plant that grows in salt marches and on muddy seashores. In order to understand the biochemical and molecular mechanisms of salt tolerance in S. herbacea, we isolated several genes that involved in the salt tolerance by mRNA differential display.Here we report the cloning of a cDNA encoding fructose-1, 6-bisphosphate aldolase, named ShADL, which is 1293 bp long and contains an open reading frame consisted of 359 amino acids with calculated molecular mass of 39 kDa. ShADL protein showed 86% identity with Arabidopsis and 78% with aldolase of common ice plant. Northern blot analysis revealed that the transcript of ShADL gene was increased dramatically depending on the NaCI concentrations.