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- 저자 : Ceylan (검색결과 44 건)
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Isil Erem Ceylan,Fatih Ceylan 세종대학교 경제통합연구소 2023 Journal of Economic Integration Vol.38 No.4
This study examined the symmetric and asymmetric effects of exchange rate changes on stock prices in the economies of India, Indonesia, Brazil, South Africa, and Turkey, collectively known as the "Fragile Five" due to their similar economic dynamics in light of the global financial crisis and pandemic period. The study uses monthly data from July 2000 to July 2022, and panel autoregressive distributive lag and panel nonlinear autoregressive distributive lag models to investigate the effects of exchange rate changes on stock prices in the Fragile Five economies. Prior to the global financial crisis, exchange rate changes have both long- and short-term asymmetric effects on stock prices in the Fragile Five economies. However, after the global financial crisis, exchange rate changes have both short- and long-term asymmetric and symmetric effects. Similarly, exchange rate changes also have asymmetric effects on stock prices during the COVID-19 period.
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Effect of polymer concentration in cryogelation of gelatin and poly (vinyl alcohol) scaffolds
Ceylan, Seda,Demir, Didem,Gul, Gulsah,Bolgen, Nimet Techno-Press 2019 Biomaterials and Biomechanics in Bioengineering Vol.4 No.1
The aim of this study was to investigate the effect of total polymer concentration on the chemical structure, morphology of pores, porosity, swelling ratio, degradation of gelatin-poly (vinyl alcohol) (Gel-PVA) cryogel scaffolds. Porous cryogels were prepared with cryogelation technique by using glutaraldehyde as a crosslinker. Functional group composition of cryogels after crosslinking was investigated by Fourier Transform Infrared (FTIR). The morphology of cryogels was characterized via scanning electron microscopy (SEM) and porosity analysis. All of the cryogels had a porous structure with an average pore size between $45.58{\pm}14.28$ and $50.14{\pm}4.26{\mu}m$. The cryogels were biodegradable and started to degrade in 14 days. As the polymer concentration increased the swelling ratio, the porosity and the degradation rate decreased. Spongy and mechanically stable Gel-PVA cryogels, with tunable properties, can be potential candidates as scaffolds for tissue engineering applications.
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A review on three dimensional scaffolds for tumor engineering
Ceylan, Seda,Bolgen, Nimet Techno-Press 2016 Biomaterials and Biomechanics in Bioengineering Vol.3 No.3
Two-dimensional (2D) cell culture and in vivo cancer model systems have been used to understand cancer biology and develop drug delivery systems for cancer therapy. Although cell culture and in vivo model studies have provided critical contribution about disease mechanism, these models present important problems. 2D tissue culture models lack of three dimensional (3D) structure, while animal models are expensive, time consuming, and inadequate to reflect human tumor biology. Up to the present, scaffolds and 3D matrices have been used for many different clinical applications in regenerative medicine such as heart valves, corneal implants and artificial cartilage. While tissue engineering has focused on clinical applications in regenerative medicine, scaffolds can be used in in vitro tumor models to better understand tumor relapse and metastasis. Because 3D in vitro models can partially mimic the tumor microenvironment as follows. This review focuses on different scaffold production techniques and polymer types for tumor model applications in cancer tissue engineering and reports recent studies about in vitro 3D polymeric tumor models including breast, ewing sarcoma, pancreas, oral, prostate and brain cancers.
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Wear behavior of irregular shape Ti6Al4V powder reinforced with carbon nanotubes
Muhammet Ceylan,İsmail Topcu 한양대학교 세라믹연구소 2020 Journal of Ceramic Processing Research Vol.21 No.5
The purpose of this study was to investigate the sintering behavior, microstructural evolution, and the effect on wear resistanceof carbon nanotubes (CNT) with the addition of a mechanical alloy (Ti6Al4V) and sintered irregular Ti64 powder. Themechanical alloy powders utilized in this study were produced through the process of CIP (Cold Isostatic Press) in order toproduce samples by compress on under various pressures within a 300 MPa floating molded press. The samples were sinteredat a high vacuum (10-5 mbar) for 60 minutes at a temperature of 1275 oC. After sintering, the materials were characterizedusing an optic microscope (OM), scanning electron microscopy (SEM) and EDX (Energy-dispersive X-ray spectroscopy) todetermine whether the materials had wear resistance, density measurement, etc. The Carbon Nanotube wear and frictionbehavior were investigated under various conditions using a pin wear tester on a disc followed by a scanning electronmicroscopy (SEM) analysis. The objective of this study was to evaluate the density, metallographic properties and hardnessof Ti64 samples supplemented with different CNT ratios as a function of sintering temperature. Theoretical density and microhardnessof mechanical alloyed and sintered irregular Ti64 powders changed with the additions to CNT under increasedsintering temperatures.
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Ozgur Ceylan,Aysel Ugur 대한약학회 2015 Archives of Pharmacal Research Vol.38 No.6
In this study, antimicrobial and antibiofilmactivities and the chemical composition of Thymus sipyleusBOISS. subsp. sipyleus BOISS. var. davisianus RONNIGERessential oil was evaluated. The essential oil wasobtained by hydro-distillation and analyzed by gas chromatography-mass spectrometry. Fourteen compounds werecharacterized, having as major components thymol(38.31 %) and carvacrol (37.95 %). Minimum inhibitoryconcentrations (MICs) of oil and the major componentswere calculated by serial dilution method, and anti-biofilmeffects by microplate biofilm assay against five Grampositive (Staphylococcus aureus MU 38, MU 40, MU 46,MU 47, Stahylococcus epidermidis MU 30) and five Gramnegative (Pseudomonas aeruginosa MU 187, MU 188, MU189, Pseudomonas fluorescens MU 180, MU 181) bacteria. It was found that MICs for essential oil, thymol and carvacrolwere between 5 and 50 ll/ml, 0.125–0.5 lg/ml and0.125–05 ll/ml, respectively. The results showed thatdoses of MIC produced a greater anti-biofilm influencethan 0.5, 0.25 and 0.125 MIC. In the presence of essentialoil (MIC), the mean biofilm formation value was equal to67 ± 5.5 % for P. aeruginosa MU 188, and essential oil(MIC) inhibition exceeds 60 % for P. aeruginosa biofilms. The results also showed that carvacrol (MIC) was able toinduce an inhibition 72.9 ± 4.1 % for S.aureus (MU 40)biofilm. In addition, thymol (MIC) showed 68.6 ± 5.3 %reduction in biofilm formation of P. fluorescens MU 181. This study demonstrated the antimicrobial and antibiofilmactivity of T. sipyleus BOISS. subsp. sipyleus BOISS. var. davisianus RONNIGER essential oil and points out theexceptional efficiency of thymol and carvacrol, whichcould represent candidates in the treatment of Pseudomonasand Staphylococcus biofilms.
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Cuisine culture of the pearl of Mesopotamia: Mardin, Turkey
Jiyan Aslan Ceylan,Ayse O. Ozcelik 한국식품연구원 2018 Journal of Ethnic Foods Vol.5 No.4
Background: Mardin, which is located in Southeast Anatolia and hosts the generosity of Mesopotamia, has a significant contribution to Turkey's cuisine culture. This study was conducted to investigate the cuisine cultures of the indigenous families living in the central district of Mardin. Methods: The sampling of the study consisted of 300 families living in Artuklu and described as native. The study was conducted with married women aged between 20 and 65 years who were responsible for family feeding. The data were collected through face-to-face interviews using a questionnaire form. Data analysis of the study was conducted using Statistical Package for the Social Sciences package program. Statistical significance was evaluated at p < 0.05. Results: It was found that 51.7% of the families eat their meals in the kitchen, 81.1% of the families with a high number of members eat on the floor table, and 57.6% of the families with a low number of members eat on the dining table (p < 0.05). It was determined that the cooking rate of local dishes and desserts is higher in the families of unemployed women (p < 0.05). Conclusion: As each country has a unique cuisine culture, Turkey also has a rich cuisine culture that falls into distinct forms according to the regions and provinces. Mardin, which is located in Southeast Anatolia and hosts the generosity of Mesopotamia, has a significant contribution to Turkey's cuisine culture.
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Mehmet Emin Ceylan,Bariş Önen Ünsalver,Alper Evrensel 대한정신약물학회 2018 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.16 No.1
Bipolar affective disorder (BD) diagnosis and initiation of appropriate treatment are often delayed, and this is associated with poorer outcomes, such as rapid cycling or cognitive decline. Therefore, identifying certain warning signs of a probable successive episode during the inter-episode phase is important for early intervention. We present the retrospective data of three cases of BD. Our first case had a history of alcohol use disorder (AUD), where he drank in a dipsomaniac manner, and the other two cases had dipsomaniac alcohol use before their manic attacks, and none of them had any AUD after the mood episode was over. Two brothers also had hypertensive episodes during the manic attacks. None of the cases reported increased fluid intake when they were euthymic. We suggest that polydipsia in BD may be a warning sign of an upcoming manic episode, especially in those patients with AUD. Polydipsia in BD may be caused or facilitated by a combination of hyperdopaminergic activity, hypothalamic dysfunction, and dysregulated renin-angiotensin system. To be able to prevent new episodes, a patient’s drinking habits and change in fluid intake should be asked at every visit. Those patients with a history of alcohol abuse should especially be informed about polydipsia and manic episode association.
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