Nanogenerators: Fully Rollable Transparent Nanogenerators Based on Graphene Electrodes (Adv. Mater. 19/2010)

Choi, Dukhyun,Choi, Min-Yeol,Choi, Won Mook,Shin, Hyeon-Jin,Park, Hyun-Kyu,Seo, Ju-Seok,Park, Jongbong,Yoon, Seon-Mi,Chae, Seung Jin,Lee, Young Hee,Kim, Sang-Woo,Choi, Jae-Young,Lee, Sang Yoon,Kim, Jo WILEY-VCH Verlag 2010 ADVANCED MATERIALS Vol.22 No.19

<B>Graphic Abstract</B> <P>The cover shows an image of fully rollable transparent nanogenerators synthesized using chemical vapor deposition grown large-scale graphene sheets as transparent electrodes and piezoelectric ZnO nanorod arrays. Sang-Woo Kim, Jae-Young Choi, and co-workers report on p. 2187 the electrical and structural stability of the nanogenerators, with excellent charge scavenging performance under external mechanical loads such as bending and rolling. This study shows that graphene-based nanogenerators are very promising for self-powered rollable transparent device applications. <img src='wiley_img_2010/09359648-2010-22-19-ADMA201090066-content.gif' alt='wiley_img_2010/09359648-2010-22-19-ADMA201090066-content'> </P>

산업단지 및 일반생활 지역의 공기 중 톨루엔에 대한 개인노출 및 생체시료의 상관성 분석

이병준(Byoungjun Lee),허 정(Jung Heo),정다영(Dayoung Jung),김순신(Sunshin Kim),류현수(Hyeon-Su Ryu),최민지(Min-Ji Choi),솨이지엔페이(Jian-Fei Shuai),임성국(Sung-Guk Im),양원호(Wonho Yang) 한국환경보건학회 2017 한국환경보건학회지 Vol.43 No.4

Objectives: The purpose of this study was to assess the correlation relationship between personal exposure and urinary hippuric acid in biological monitoring for airborne toluene in an industrial complex and in general environments. Methods: Personal exposure to toluene and its metabolite, hippuric acid, in urine were simultaneously measured in occupational environments area near an industrial complex and in general environments. The study subjects were divided into three types: 137 workers who use organic solvents in the workplace, 210 residents living near a dyeing industrial complex, and 379 residents living in general environments. The toluene exposures of workers and residents were measured by a passive sampler for four days. The urine of participants was sampled when the passive samplers of personal exposure were collected. Results: The toluene and hippuric acid concentrations of workers were the highest, followed by the concentrations of residents living near a dyeing industrial complex and residents living in general environments. The coefficient of correlation between the concentrations of toluene and hippuric acid among workers was 0.749 (p<0.01) in the workplace. On the contrary, correlations between the concentrations of toluene and hippuric acid among residents living near a dyeing industrial complex and residents living in general environments were all not significant. The relationship between the concentrations of hippuric acid and toluene in three types could be described by the exponential growth model. Conclusions: This study analyzed the relationships between toluene exposure and the concentrations of hippuric acid in urine in high, middle, and low exposure environments, and could be described by the exponential growth model.

2-Octyl Cyanoacrylate Glue Application on Split-Thickness Skin Graft for Lower Extremity Reconstruction

Choi Bu Hyeon,Cho Kyu Sang,장정우,Lee Jang Hyun 대한창상학회 2021 Journal of Wound Management and Research Vol.17 No.3

A split-thickness skin graft (STSG) is a very effective method for reconstructing skin defects in the lower extremities; however, suturing all graft margins during surgery is time-consuming. As an alternative, 2-octyl cyanoacrylate glue attaches the epidermal layer of an STSG to normal skin and functions like a suture. In this study, we assessed 2-octyl cyanoacrylate glue as a time-saving step in STSG procedures. We reviewed the charts of 87 patients who underwent STSG between May 2018 and August 2020. For the 10 patients who consented to the STSG procedure with 2-octyl cyanoacrylate glue, we evaluated the treatment site for complications and engraftment every 2 days for 14 days. The STSGs were successfully engrafted in all cases. Seroma, hematoma, wound dehiscence, or infection were not documented. No additional revision surgery was required. The use of 2-octyl cyanoacrylate glue in STSG margin fixation was safe, effective, convenient, and time-saving. This study found 2-octyl cyanoacrylate glue a good option for lower extremity skin defect reconstruction.

Genetic diversity and population structure of the long-tailed goral, Naemorhedus caudatus, in South Korea.

Choi, Sung Kyoung,Chun, Suwon,An, Junghwa,Lee, Mu-Yeong,Kim, Hyeon Jeong,Min, Mi-Sook,Kwon, Soo-Wan,Choi, Tae Young,Lee, Hang,Kim, Kyung Seok Genetics Society of Japan 2015 Genes & genetic systems Vol.90 No.1

<P>The long-tailed goral, Naemorhedus caudatus, is an internationally endangered species. This species is distributed throughout Northeastern Asia including Northeastern China, the Russian Far East and the Korean peninsula. The population size of long-tailed gorals is currently decreasing in South Korea, and thus effective conservation of the animal is urgently needed. Although the evolution and phylogeny of this animal have been studied, population genetic studies are needed to design effective conservation and management strategies. To evaluate the present status of genetic diversity and genetic structure of long-tailed gorals in South Korea, we investigated genetic variability among 68 goral individuals from different regions, including 11 captive zoo animals, at 12 microsatellite loci. The level of genetic diversity was moderate in wild goral populations, but lower in the captive group. The goral population from the lower northeast region of South Korea was distinct from the upper northeast population, probably due to the natural climatic and geographic conditions. The genetic characteristics of the captive group were more similar to those of the upper northeast population than the lower northeast, confirming that the zoo animals originated in the Seorak Mountain range. Direct translocations between the upper and lower northeast populations are not currently recommended considering the natural population structure and the moderate levels of genetic diversity in the two populations. This study highlights the importance of genetic information in designing effective conservation strategies and translocations of endangered animals, including the Korean goral.</P>

Bi-modified Pt supported on carbon black as electro-oxidation catalyst for 300 W formic acid fuel cell stack

Choi, Mihwa,Ahn, Chi-Yeong,Lee, Hyunjoon,Kim, Jong Kwan,Oh, Seung-Hyeon,Hwang, Wonchan,Yang, Seugran,Kim, Jungsuk,Kim, Ok-Hee,Choi, Insoo,Sung, Yung-Eun,Cho, Yong-Hun,Rhee, Choong Kyun,Shin, Woonsup Elsevier 2019 Applied Catalysis B Vol.253 No.-

<P><B>Abstract</B></P> <P>Formic acid is a chemical with a simple molecular structure containing hydrogen. This liquid at room temperature is easy to handle and has a low toxicity, and is thus in the spotlight as a fuel. In particular, formic acid is an excellent fuel candidate because it can be operated at low temperatures when applied as a fuel in fuel cells with a high theoretical open-circuit voltage (1.48 V). However, it has a drawback in that the electrode catalyst is deactivated due to the generation of CO intermediates when formic acid is oxidized during cell operation. Therefore, to prevent this, an irreversibly adsorbed Bi on Pt catalyst is applied to a direct formic acid fuel cell (DFAFC) anode because it is easy to synthesize and economical. Physical analyses such as transmission electron microscopy (TEM), X-ray diffraction (XRD), and thermogravimetric analysis (TGA) were conducted, and electrochemical evaluations were performed through half-cell and single-cell level tests. The results revealed that the formic acid oxidation reaction activity of the Bi-modified Pt/C was 13 times higher than that of the conventional catalyst at 0.58 V. Further, a DFAFC stack was fabricated using the Bi-modified Pt/C, which yielded a power of 300 W. These results suggest that a simple synthesis method can be applied to fabricating industrially available DFAFC stacks.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Bi-modified Pt catalyst is applied to a direct formic acid fuel cell (DFAFC) anode. </LI> <LI> Bi was irreversibly adsorbed on Pt catalyst by a simple synthetic strategy. </LI> <LI> Bi-modified Pt/C showed significantly high formic acid oxidation reaction activity. </LI> <LI> A DFAFC stack fabricated using Bi-modified Pt/C yielded a power of 300 W. </LI> <LI> The simple synthetic strategy can be applied to achieving DFAFC stacks commercially. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

JAG1 Intracellular Domain JICD1 Forms Novel Transcription Complex with DDX17, SMAD3, TGIF2 without Contact Notch Receptor

Hyeon Ju JEONG,Eun-Jung KIM,Jung Yun KIM,Seok Won HAM,Sang-Hun CHOI,Nayoung HONG,Min Gi PARK,Junseok JANG,Sunyoung SEO,Sung-Ok KIM,Sung-Chan KIM,Hyunggee KIM 한국생물공학회 2021 한국생물공학회 학술대회 Vol.2021 No.10

The Jagged-1 (JAG1) is a Notch ligand that contact-dependently activates Notch receptors and regulates cancer progression. When Notch receptor activate, NOTCH intracellular domain (NICD) is released through proteolytic cleavage and forms transcription complex. Here, we show that JAG1 also releases JAG1 intracellular domain (JICD1) and JICD1 forms a transcription complex with DEAD-Box Helicase 17, SMAD Family Member 3, and TGFB induced factor homeobox 2. The JICD1 transcription complex binds to the promoter of Sex determining region Y-box 2 (SOX2) and regulates transcription of SOX2. JICD1 promotes acquisition of glioblastoma (GBM) stem cell properties by JICD1 transcription complex mediated SOX2 expression. JAG1 is highly expressed in GBM and induce reverse signal via JICD1 transcription complex. By regulating transcription of SOX2, JICD1 transcription complex is an important player in the maintenance of GBM properties. The inhibition of JICD1 transcription complex may be a novel strategy to target Notch signal.

포도 ‘거봉’ 2기작재배를 위한 하계휴면타파에서 토양수분 조절과 휴면타파제 처리가 발아에 미치는 영향

Sung Do Oh(오성도),Yong Hyeon Kim(김용현),Dong Geun Choi(최동근) (사)한국생물환경조절학회 2002 시설원예‧식물공장 Vol.11 No.2

Fully Rollable Transparent Nanogenerators Based on Graphene Electrodes

Choi, Dukhyun,Choi, Min-Yeol,Choi, Won Mook,Shin, Hyeon-Jin,Park, Hyun-Kyu,Seo, Ju-Seok,Park, Jongbong,Yoon, Seon-Mi,Chae, Seung Jin,Lee, Young Hee,Kim, Sang-Woo,Choi, Jae-Young,Lee, Sang Yoon,Kim, Jo WILEY-VCH Verlag 2010 Advanced Materials Vol.22 No.19

<B>Graphic Abstract</B> <P>Fully rollable transparent nanogenerators have been developed using chemical vapor deposition-grown large-scale graphene sheets as transparent electrodes and piezoelectric ZnO-nanorod arrays. The electrical and structural stability of the nanogenerators with excellent charge scavenging performance under external mechanical loads such as bending and rolling shows that graphene-based nanogenerators are suitable for self-powered rollable transparent device applications. <img src='wiley_img_2010/09359648-2010-22-19-ADMA200903815-content.gif' alt='wiley_img_2010/09359648-2010-22-19-ADMA200903815-content'> </P>

Letter to the Editor : A Case of Capecitabine and Cisplatin-induced Cutaneous Hyperpigmentation

( Sang Hyeon Hwang ),( Ji Hye Park ),( Chong Won Choi ),( Ga Young Lee ),( Won Serk Kim ) 대한피부과학회 2014 大韓皮膚科學會誌 Vol.52 No.3

The sudden appearance of multiple hyperpigmentation lesions on palms and soles is a rare phenomenon. We here report a case of focal acral hyperpigmentation in a patient undergoing chemotherapy with capecitabine and cisplatin. A 70-year-old man undergoing chemotherapy with capecitabine and cisplatin for metastatic gastric cancer was referred to our department with several pigmented macules and patches on the palms and soles (Fig. 1). The lesions appeared suddenly after the first cycle of treatment (cumulative dose, 35 g of capecitabine and 80 mg of cisplatin). Histopathological examination of the pigmented macules revealed melanocytes and melanin in the basal layer (Fig. 2). We care- fully followed the patient for any changes in color, size, and shape of the lesions, but the pigmented lesions persisted without any change until the patient died of pneumonia after sixth cycles of chemotherapy. Capecitabine is an oral antineoplastic agent, which is converted to 5-fluorouracil (5-FU) in the body. A well-known side effect of 5-FU on the skin is the hand-foot syndrome (HFS) or palmar-plantar erythrodysaesthesia1. However, acral hyperpigmentation is rarely reported. A previous report of capecitabine-induced hyperpigmentation noted a similar, but more generalized, distribution of the pigmented macules seen in this case2. Conversely, cisplatin-induced hyperpigmentation is rarely reported, and the predilection sites, such as the periungual areas, are prone to repeated irritation3. It has been proposed that a combination of altered immune surveillance and certain anatomic trophic factors present in the skin of the palms and soles play a role in the development of palmoplantar pigmented lesions4. In this case, it is thought that capecitabine contributed more to the development of the lesions on the palms and soles, although both capecitabine and cisplatin may be responsible for the development of hyperpigmentation. This case report adds novel information to the data available on capecitabine and cisplatin-induced cutaneous hyperpigmentation. Although cutaneous hyperpigmentation is not a common side effect in capecitabine and cisplatin treatment 2, 3, hyperpigmentation due to these medications may be more common than reported, and clinicians should hence be aware of this focal cutaneous adverse effect.

Comparative Outcome after Treatment for Synchronous vs. Metachronous Colorectal Cancer Liver Metastasis

Sang Min Youn,Jin Seok Heo,Dong Wook Choi,Seong Hyeon Yun,Ho Kyung Chun,Woo Yong Lee,Seong Ho Choi,Hee Cheol Kim,Yong Bum Cho 한국간담췌외과학회 2010 한국간담췌외과학회지 Vol.14 No.3

Purpose: This study was designed to compare outcomes in patients who underwent hepatectomy or radiofrequency thermal ablation (RFA) for synchronous or metachronous colorectal liver metastases (CLM). Methods: One hundred twenty-two patients who underwent hepatectomy or RFA for their first CLM between 2001 and 2004 were enrolled in this study. The patients were divided into two groups (synchronous [N=77] and metachronous [N=45] CLM). Patient characteristics, clinicopathologic features, long-term outcomes, and prognostic factors were analyzed retrospectively. Results: There were no significant differences in the 5-year disease-free and overall survival rates between the synchronous and metachronous CLM groups (36.2% vs. 37.2%, p=0.78; and 53.0% vs. 54.4%, p=0.82, respectively). Patients in the synchronous CLM group underwent more bilobar hepatic resections, intra-operative RFA, or co-modality treatments than the metachronous CLM group (p=0.035). The surgical resection group had a longer disease-free survival, but not overall survival than the RFA group. Greater N stage and female gender were associated with a worse prognosis in overall survival; N0 stage and surgical resection were good prognostic factors for disease-free survival. N stage and surgical resection were also statistically significant prognostic factors based on multivariate analysis. Conclusion: The synchronicity of CLM is not a significant prognostic factor, but the clinicopathologic characteristics that reflect more disseminated disease than metachronous metastasis are significant prognostic factors. Tumor characteristics and aggressiveness may be more important for prognosis than chronology.