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      • 방사선 조사에 의한 phospholipase D 활성화 연구

        김영래,김기환,조문준,임규,황병두,박승길 충남대학교 의과대학 의학연구소 2002 충남의대잡지 Vol.29 No.1

        Activation of oleate-dependent phospholipase D (PLD) isozyme by irradiation was reported previously. However, the effects of irradiation on other PLD isotypes (PLD1 and PLD2) have not been studied. There are several kinds of PLD isozymes in a cell. Therefore, it is difficult to study PLD isotype-specific activation in a cell by irradiation. We tested which isotype of PLD responds to irradiation. We used the fibroblasts cell lines overexpressing PLDl or PLD2 by introducing recombinant PLD1 or PLD2 cDNA. Phospholipids in cells were labelled with [(3)^H] myristic acid. Before irradiation, l-butanol was added. After irradiation with doses of 1, 2, and 10 Gray, we measured the formed phosphatidylbutanol containing [(3)^H] myristic acid. The overexpressed PLD isotypes were functional in those cell lines. PLD2 activity was enhanced by irradiation when we compared the PLD activations between control and PLD1 or PLD2 overexpressing cells. However PLD1 was not activated by irradiation. PLD2 isozyme, but not PLD1, was activated by irradiation. One Gray irradiation showed the maximal effect on PLD2 activation. The activation mechanism and physiological significance of PLD2 activation by irradiation remain to be uncovered.

      • KCI등재

        Magnetic Resonance Imaging and Pathologic Correlation of Cerebral Fat Embolism using Oleic Acid

        박병래 THE KOREAN SOCIETY FOR BIOMEDICAL LABORATORY SCIEN 2004 Journal of biomedical laboratory sciences Vol.10 No.2

        To investigate the correlation between the magnetic resonance imaging (MRI) of cerebral fat embolism that is induced by injecting oleic acid into 10 cats, and a pathologic diagnosis. Using a microcatheter, 30 μl of oleic acid was injected into the internal carotid artery of 10 cats. MR T2-weighted image (T2WI), diffusion-weighted image (DWI) and Gadolinium-enhanced T1-weighted image (Gd-enhanced T1WI) were obtained after 30 minutes and 2 hours of embolization. After 30 minutes of the embolization, lesions of very high signal intensity were detected by T2WI in 6 cats, and of slightly high signal intensity in 2 cats; in the remaining 2 cats, signal intensity was normal. DWI showed lesions of very high intensity in 9 cats and of slightly high intensity in one cat. According to the findings of light microscopic examination, infarcted lesions mainly involved the gray matter, but also some white matter. A magnetic resonance imaging diagnosis for cerebral fat embolism that was induced by oleic acid through the internal carotid artery in cats showed high signal intensity on the T2WI and the DWI within an initial 2 hours, and with a well enhancement on the Gd-enhanced T1WI. Considering cellular edema, cerebrovascular injury and extracellular space widening, we assumed pathologically that cytotoxic and vasogenic edema exists at the same time.

      • MRAC를 이용한 로보트 매니퓰레이터의 制御性能 向上에 관한 硏究 : Model Reference Adaptive Controller

        김병수,김규로,선양래 慶熙大學校 大學院 1995 高凰論集 Vol.16 No.-

        This paper is study on trajectory property of 6 DOF robot manipulator. This paper used to adaptive control and p-d(proportional-derivated) control for control methods, Simulation robot is stanford 6-dof robot manipulatr of stanford university. Main results obtained through this paper are summarized as followings. At each links, adaptive control has more excellant control than p-d control. At 1-st link, adaptive control and p-d control has a little error at 3.0 second. At 2 nd link, adaptive control and p-d control has a little error than other links without 3-rd link, At 3-rd link, two control methods has a superiority control results than other links with two control methods. At 5-st link, p-d control error is a most great than other links. Therefore, the adaptive control applications for 6-dof robot manipulator has a very excellant capability than applying classical p-d control.

      • 복사 장치를 이용한 온도와 형상계수의 변화에 따른 방사율에 관한 실험적 연구

        김청래,정병철,강형석 강원대학교 산업기술연구소 2005 産業技術硏究 Vol.25 No.B

        Voltage of radiometer is measured experimentally using the radiation apparatus in each case of iron- and copper-plates as specimen heating device. The length between radiometer and conical shield and the temperature of specimen heating device are considered as variables. The length between radiometer and conical shield controls the amount of radiation from the specimen heating device. Emissivity for both iron-and copper-plates are calculated by using Stefan-Boltzmann equation. One of results shows that emissivity for both materials increases as the length between radiometer and conical shield increase.

      • 韓國 福祉政策의 方向과 課題 : 醫療保障을 중심으로 the Medical Security system

        朴炳來 대구효성카돌릭대학교사회과학연구소 1998 사회과학연구 Vol.5 No.-

        The purpose of this study is to examine Medicare system of Korea. There are many problems in korean Medicare system, especially unreasonableness of levy a medical premium, limit and level of insurance money payment etc. This study shows that the development of Korean Medicare system was influenced by socio-structural elements and socio-economic aspects. The former is a strong bond of Korean family, nonofficial social support, nonofficial cultural solidarity etc., the latter is the phase and level of economic development. Therefore this study come to the conclusion that its demand for explanation about the relations between the policies of medical insurance and the characteristics of the phase and level of nation development.

      • 들민달팽이(Deroveras varians)의 배자발육과 난황단백질

        진병래,손흥대,박혜진,조은숙 東亞大學校附設 農業生命科學硏究所 1999 農業生命資援硏究 Vol.8 No.1

        들민달팽이의 배자발육은 해부현미경으로 관찰하였다. 산란 후 4일이 경과면서 발육이 급격하게 진전되어, 10일이 지나면서 난 내에서 들민달팽이 유충의 형태를 갖추고, 12일째 부화하였다. 들민달팽이의 배자발육에 따른 난황단백질의 변화는 산란 1일째, 3일째 및 6일째 알의 난황단백질을 전기영동방법으로 분석하였다. 그 결과 배자발육과 함께 급격히 감소되는 난황단백질 관련 밴드를 관찰할 수 있었다. We characterized embryogenesis and egg proteins of Variable field Slug, Deroceras varians. The embryogenesis was observed by light microscopy. The eggs were hatched at the twelfth day after oviposition. The egg proteins of the first day, third day and sixth day after oviposition were analyzed by native-and SDS-PAGE analyses. The results showed that yolk proteins are gradually decreased during embryogenesis.

      • Jini 기반 전자상거래 구조의 설계

        이병래,김지균,이명선 高麗大學校附設 컴퓨터科學技術硏究所 1999 JOURNAL OF COMPUTER SCIENCE & ENGINEERING TECHNOLO Vol.1 No.-

        시간이 지날수록 다양한 장소는 네트워크화 되고 있으며, 많은 종류의 전자 기계와 소프트웨어 또한 네트워크화 되고 있다. 이러한 조건하에서, 분산 환경은 필수적인 요건이 될 것이고, 전자 기계 또는 소프트웨어들의 호환성은 고려되어야 할 것이다. 이 논문에서는 Jini를 기반으로 한 전자상거래 구조를 제시한다. Jini 시스템은 Java 중심적인 분산 시스템으로서 단순성, 유연성 그리고 연합성을 특징으로 하고 있다. Jini 구조는 머신 또는 프로그램들이 연합체에 참가하여 다른 멤버들에게 리소스를 제공하고 필요한 리소스를 사용하는 기반을 제공한다. Jini 구조는 Java 언어 코드의 이동성을 취하여 service라는 개념 하에, Jini 시스템의 사용자로부터 이용되는 하드웨어에서의 소프트웨어 또는 하드웨어 자신의 컴포넌트들까지 통합한다. In the future, Countless place should be networked and Countless variety of money-related electronic requirement, and electronic machine's interoperability should be concerned. In this paper, we propose Jini based electronic commerce architecture. A Jini system is a Javatm-centric distributed system designed for simplicity, flexibility, and federation. The Jini architecture provides mechanisms for machines or programs to enter into a federation where each machine or program offers resources to other members of the federation and uses resources as needed. The design of the Jini architecture exploits the ability to move Java language code from machine to machine and unifies under the notion of a service everything from the user of a Jini system to the software available on the machines to the hardware components of the machines themselves.

      • 적응형 사용자 인터페이스가 가능한 다중 에이전트 기반 전문 분야 검색 엔진 설계

        차병래,조혁현 여수대학교 1999 論文集 Vol.14 No.2

        The requirement for information retrieval is on the increase recently by the explosive access on WWW. Existed search engines do not support the user requirement correctly. To increase the correctness on searched result, the interactive architecture between user and engine is needed. By increasing information on web and flexibility on user preference, various results are needed on a query. In order to overcome the problem, we propose the adaptive user interface on search engine. Firstly, it accumulates user preferences on the user profile. Secondly, it reorganizes the query domain. Lastly, it filters the result for user needs.

      • 베이지안 방법을 활용한 침입 탐지

        차병래,서재현 국립7개대학공동논문집간행위원회 2001 공업기술연구 Vol.1 No.-

        In this paper, we produce prior information from system environments and compute prior probability. We represent state transition processing of command execution using bayesian method. Bayesian probability transformation of system state maintained during session continuously. To session end, post-audit performed to afford a basis for probability transformation automatically. In this study, we applied bayesian method to Intrusion detection using system state and transition. Lastly, we performed simulation to reduce intrusion misuse and false positive using Shieh model.

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