BSA고정화를 위한 가교제의 첨가특성

김재훈,김민,김병식 한국공업화학회 2004 응용화학 Vol.8 No.2

Anion exchange groups(DEA) were introduced into porous hollow fiber membranes by radiation-induced ploymerization. A DEA group-containing polymer chain grafted onto a porous PE membrane. The BSA solution was forced to permeate across the hollow fiber DEA membrane. BSA was immobilized by the permeation of a BSA solution through the pore of the DEA membrane. The immobilized BSA was cross-linking with glutaraldehyde to prevent leakage. Afterwards, The GA 0.05 percent membrane having higher adsorption capacity than 0.025, 0.075, 0.1 percent GA concentration.

신생아에서의 HDL-C와 LDL-C 値에 관한 연구

한병길,정용헌 충남대학교 의과대학 지역사회의학연구소 1996 충남의대잡지 Vol.23 No.1

The values of serum HDL-C and LDL-C were measured in 70 newborn infants with gestational ages from 35-43 weeks, birth weight from 2000 to 4500 gm, Apgar score 7 or more at 1 & 5 minutes and normal physical examination. 1. In all newborn infants, the mean HDL-C values & ranges were 31.99 ±6.67 mg/dl, from 21.5 to 49.8mg/dl, and the mean LDL-C values & ranges were 41.42 ±21.39mg/dl from 15.1 to 94.3mg/dl. 2. In term newborns with AGA, the mean HDL-C & LDL-C values were 32.85 ±6.75mg/dl and 45.85 ±21.39mg/dl respectively. 3. The HDL-C and LDI-C values of female were significantly higher than those of male. 4. The correlation of HDL-C by weight for gestational age was not significant, but that of LDL-C value was significantly lower in SGA than those of AGA & LGA. 5. The correlations of HDL-C & LDL-C according to birth weight, gestational age and Ponderal Indices were not significant.

Glutaraldehyde로 가교시킨 BSA고정막에 의한 DL-Tryptophan의 흡착특성

김재훈,김민,김병식 한국공업화학회 2004 응용화학 Vol.8 No.1

A DEA group-containing polymer chain grafted onto a porous PE membrane. BSA was immobilized by the permeation of a BSA solution through the pore of the DEA membrane. The immobilized BSA was cross-linking with glutaraldehyde to prevent leakage. DL-tryptophan solution was forced to permeate through the BSA immobilized membrane at a flow 50mL/h. As a result, Adsorption of D-L-tryptophan increase with increasing of BSA immobilized as a function of the degree of GMA grafting.

가교제를 첨가시킨 BSA고정막의 합성 및 특성

김재훈,김민,김병식 한국공업화학회 2003 응용화학 Vol.7 No.1

Bovine serum albumin(BSA) as a chiral ligand was captured uniformly throughout a porous hollow-fiber membrane at a level of 250mg/g by the polymer chains grafted onto the membrane. Subsequetly, crosslinking of BSA with a 0.05%(w/w) of glutaraldehyde in a Tris-HCL buffer (pH 8) for 5 h was effective in stabilizing the amount of BSA immobilized at a level of 200 mg/g. A solution of 이-Tryptophan in Tris-HCI buffer asa mobile phasa permeated the crosslinked-BSA multilayered membrane. Therefore on experimentation is BAS immobilized hollow fiber is applicable for the chiral separation of enantiomers in a mobile phase with various pH values and organic modifiers.

갑상선 기능항진증에 병발된 주기성 마비 3예

최지훈,최경숙,김기훈,박병현,조정구 圓光大學校 醫科學硏究所 2001 圓光醫科學 Vol.16 No.1-2

Thyrotoxic periodic paralysis is characterized by intermittent flaccid paralysis of skeletal muscle, lasting several hours. The underlying pathophysiology of the syndrome is not yet to be well characterized and remains controversal, but reflects altered potassium and calcium dynamics as well as certain morphologic characteristics within the muscle unit itself. It occurs primarily in Asian populations with an overwhelming male preponderance and a higher association of specific HLA antigens. Precipitating factors include high carbohydrate ingestion, exercise, trauma, infection, alcohol ingestion, administration of epinephrine, thyroid hormone, or corticosteroid. If hypokalemia is present, potassium administration may help abort the attack, but the only definitive treatment is formation of euthyroid state. We discribed two patients with hypokalemic thyrotoxic periodic paralysis and one patient with normokalemic thyrotoxic periodic paralysis.

이성질체 분리를 위한 음이온교환재료의 합성

김재훈,김민,김병식 한국공업화학회 2003 응용화학 Vol.7 No.2

Anion exchange groups were introduced into porous hollow fiber membranes by radiation-induced ploymerization. The epoxy group produced in the GMA-grafted hollow fiber membrane was converted into anion-exchange groups by reaction with Diethylamine(DEA). Triethylamine(TEA). Ethanolamine(EtA). Diethanolamine(DEtA). The D-, L-Tryptophan solution was forced to permeate across the hollow fiber DEA, TEA, EtA, DEtA memberan. When measurements of anion-exchange capacity of the DEA, TEA, EtA, DEtA memberan, the DEA membrane having higher adsorption capacity than TEA, EtA, DEtA membrane.

다공성 실리콘의 제작 및 특성 연구

문병훈,최석호 慶熙大學校 材料科學技術硏究所 1994 材料科學技術硏究論集 Vol.7 No.-

Microstructure, photoluminescence(PL) spectra, persistent photocurrent(PPC), adsorbates and bias effects on current, and FTIR(Fourier Transform Infrared Spectroscopy) spectra have been studied for porous silicon(PS) samples fabricated under various preparation conditions. There has been found no relation between pore size of PS and its PL peak energy, but strong relation between metastable effects such as current changes due to light, air and bias and chemical adsorption of air molecules on its surface. These experimental results are explained based upon adsorbates related band scheme.

악교정 수술 환자에서 수술부 술전소독에 사용되는 소독제의 항균성에 대한 임상적인 비교 : POVIDONE-IODINE AND CHLORHEXIDINE

엄기훈,한세우,유준영,양병은,김용관 大韓顎顔面成形再建外科學會 2003 Maxillofacial Plastic Reconstructive Surgery Vol.25 No.2

For prevention of bacteremia and surgical field contamination, various concentration are used in preoperative skin preparation. Of these, povidone(PVP)-iodine has been known as one having believable effect. But, application of PVP-Ⅰon pral and maxillofacial field has some problems-skin discoloration, hypersensitivity, corneal irritation,etc. Therefore chlorhexidine has been tried to replace PVP-Ⅰ. More recent studies of antibacterial effect of chlorhexidine and PVP-Ⅰ has been achieved on the other field. The purpose of this study was to compare the antibactreial effect of two kinds of skin disinfectants used in oral and maxillofacial surgical field.-chlorhexidine and PVP-Ⅰ. We studied the 40 patients who have taken operation of orthognathic surgery in Dept. of oral & Maxillofacial Surgery, Kangnam General Hospital Public Corp..Results of bacterial culture taken from facial skin and intraoral mucosa after application 10% PVP-Ⅰ and 0.5% chlorhexidine were compared.

CMOS 기술을 이용한 8-bit x 8-bit 2의 보수 병렬 승산기

박병헌,정강민 成均館大學校 科學技術硏究所 1988 論文集 Vol.39 No.1

In this paper we describe a 8-bit s 8-bit 2's complement parallel multiplier using CMOS technology. Multiplication is frequently the speed--limiting function in many digital signal processing chips. Therefore ahigh-speed multiplier can greatly improve the throughput and the bandwidth of mangy digital systems, like Fourier transform processors and digital filters. The multiplier in this paper implements 2's complement multiplication by the Baugh and Wooley's algorithm, in which all the partial product bit are made positive. The layout has a highly modular structure and has been designed using the 3-㎛ CMOS polysilicon gate technology. The simulation is performed using the circuit simulator SPICE and the logic simulator EDAS-P.

킬레이트 형성기로서 Ethylenediamine을 도입한 다공성 중공사막에 의한 금속이온의 흡착특성

김헌석,김민,이영기,김병식 동국대학교 산업기술연구원 1999 산업기술논문집 Vol.14 No.-

폐수나 초순수 중의 금속이온을 효율적으로 회수하기 위해 킬레이트 형성기로서 에틸렌디아민(EDA)을 방사선그래프트중합법에 의해 생성된 그래프트 체인에 도입하였다. 그래프트율에 따른 에틸렌디아민기의 밀도를 측정하였으며, 그래프트율 177%의 경우 4.25mol/kg으로 나타났다. 에틸렌디아민기가 도입된 중공사막의 금속이온에 대한 흡착용량은 투과법에 의해 측정되었다. 투과압력의 변화에 무관한 흡착용량을 나타내었으며, 흡착된 금속이온은 용리액에 의해 100% 용리가 되었다. 구리(Cu)와 카드뮴(Cd)의 2성분 흡착에서는 구리이온이 카드뮴이온을 치환흡착 하는 것을 알 수 있었다. An ethylenediamine(EDA)-group as a chelate forming group was appended onto a hollow fiber membrane for effective recovery of metal ion from waste water or ultra pure water by radiation-induced graft polymerization of an epoxy-group-containing monomer, glycidylmethacrylate(GMA), and subsequent chemical modification. The density of EDA-group was investigated as a function of the degree of GMA grafting(dg), and it was 4.25mol/kg in case of the dg 177%. The adsorption of metal-ion onto toe EDA-hollow fiber membrane was measured by the permeation method. The metal adsorption capacity during permeation of a copper solution through the EDA-hollow fiber at various flow rate demonstrated that a higher flow rate is not affected to the collection efficiency. In the binary adsorption of Cu^2+/Cd^2+, we could see that Cu^2+ ion was substituted for Cd^2+ ion and adsorbed finally.