Ground-Glass Opacity in Lung Metastasis from Breast Cancer : A Case Report

Sae Byol Kim,Soo Hyeon Lee,Myoung Ju Koh,In Seon Lee,Chan Soo Moon,Sung Mo Jung,Young Ae Kang 대한결핵 및 호흡기학회 2013 Tuberculosis and Respiratory Diseases Vol.74 No.1

A 43-year-old woman with breast cancer who was on neoadjuvant chemotherapy presented with cough, sputum and mild fever. High-resolution computed tomography showed diffuse ground glass opacities in bilateral lungs and subpleural patchy consolidations. Initially, she was thought to have pneumonia or interstitial lung diseases such as drug-induced pneumonitis and treated with antibiotics and steroids. She subsequently got breast cancer surgery because of disease progression, and concurrent thoracoscopic lung biopsy revealed metastatic carcinoma of the lung from breast cancer. The diagnosis of suspected interstitial lung disease can be made without lung biopsy, but malignancy should always be considered and lung biopsy should be performed in the absence of a definitive clinical diagnosis.

Ground-Glass Opacity in Lung Metastasis from Breast Cancer: A Case Report

Sae Byol Kim,이수현,Myoung Ju Koh,In Seon Lee,Chan Soo Moon,Sungmo Jung,강영애 대한결핵및호흡기학회 2013 Tuberculosis and Respiratory Diseases Vol.74 No.1

A 43-year-old woman with breast cancer who was on neoadjuvant chemotherapy presented with cough, sputum and mild fever. High-resolution computed tomography showed diffuse ground glass opacities in bilateral lungs and subpleural patchy consolidations. Initially, she was thought to have pneumonia or interstitial lung diseases such as drug-induced pneumonitis and treated with antibiotics and steroids. She subsequently got breast cancer surgery because of disease progression, and concurrent thoracoscopic lung biopsy revealed metastatic carcinoma of the lung from breast cancer. The diagnosis of suspected interstitial lung disease can be made without lung biopsy, but malignancy should always be considered and lung biopsy should be performed in the absence of a definitive clinical diagnosis.

Body Mass Index and Fat Free Mass Index in Adults with COPD in Korea

( Sae Byol Kim ),( Joon Chang ),( Se Kyu Kim ),( Young Sam Kim ),( Moo Suk Park ),( Young Ae Kang ),( Song Yee Kim ),( Kyung Soo Jung ),( Kold Study Group ) 대한결핵 및 호흡기학회 2012 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.114 No.-

Background: Body mass index (BMI) and fat free mass index (FFMI) is known to decrease in patients with chronic obstructive lung disease (COPD), and low BMI and FFMI are associated with worse lung function and poor prognosis. Data are limited on the relationship between BMI, FFMI and COPD in Asian countries. Method: We used the data in Korean National Health and Nutrition Survey (KNHANES) in year 2008 to 2010, 822 subjects with COPD and the same number control subjects were selected. Spirometry and Dual Energy X-Ray Absorptiometry (DXA) were done for the analysis. Results: Subjected with COPD had lower mean BMI and FFMI compared with control group (23.6 vs. 23.9 kg/m2 and 17.2 vs. 17.5 kg/m2, p=0.015 and p=0.013, respectively). The BMI and FFMI values decreased significantly in subjects with severe airway obstruction (p<0.001). The proportion of subjects who are underweight (BMI <18.5 kg/m2) or with low FFMI (FFMI <5 percentile) was higher in GOLD stage 3-4 group (p<0.001). The deficit of FFMI was more prominent in the lower ex-tremities, followed by the upper extremities and the trunk. Subjects who are underweight had lower FEV1 and FEV1/FVC values compared with each subgroups (p<0.001). Conclusion: BMI and FFMI decreased in adults with severe COPD, and FFMI deficit was more prominent in the lower extremities. We suggest that the assessment of BMI and body composition is necessary in patients with severe airway ob-struction, and active rehabilitation has to be considered to preserve FFM for those patients. 보건복지부 보건의료연구개발사업 지원(A102065).

Pleural fluid ADA level in tuberculous pleurisy can be low in old age, critically ill patients with multi-organ failure

( Sae Byol Kim ),( Beomsu Shin ),( Ji-ho Lee ),( Seok Jeong Lee ),( Myoung Kyu Lee ),( Won-yeon Lee ),( Suk Joong Yong ),( Sang-ha Kim ) 대한결핵 및 호흡기학회 2019 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.127 No.-

Purpose: Adenosine deaminase (ADA) level in tuberculous pleural effusion (TPE) is typically elevated, but low ADA in TPE has been reported not infrequently. The characteristics of these patients are not well known. This can falsely negate the possibility of TPE, resulting in a delayed diagnosis. Method: We retrospectively reviewed patients with microbiologically or pathologically confirmed TPE between 2012 to 2018 in a tertiary hospital in South Korea. Patients were categorized into two groups: a high ADA (≥40 IU/L) and a low ADA (<40 IU/L) group. Clinical characteristics and the Sequential Organ Failure Assessment (SOFA) score were obtained and analysed. Result: A total of 192 patients with TPE were included and 36 (18.8%) had ADA <40 IU/L with a mean ADA level of 20.9 (±9.2) IU/L. Patients with low ADA were older (75.3 vs. 62.0 years, p<0.001) and showed lower lymphocyte percentage (47.6% vs. 69.9%, p<0.001) than those with high ADA. Patients in the low ADA group had significantly higher SOFA score (2.31 vs. 0.68, p<0.001), and patients with organ dysfunction were significantly more common in the low ADA group (p<0.001). Patients with 2 or ≥3 organ dysfunctions involved were 19.4% and 13.9% in the low ADA group, and 7.1% and 1.3% in the high ADA group (p<0.001). Multivariate logistic regression analysis showed that age (OR=1.030, 95% CI 1.002-1.060, p=0.038) and SOFA score (OR=1.598, 95% CI 1.239-2.060, p<0.001) were significantly associated with low ADA level in TPE. Conclusion: ADA level in TPE can be low in elderly, critically ill patients with multiorgan failure. Low ADA level cannot completely exclude the diagnosis of TPE, and physicians should be careful in interpreting pleural fluid exams.

Microorganisms in patients with endobronchial tuberculosis

( Sae Byol Kim ),( Ji-ho Lee ),( Seok Jeong Lee ),( Myoung Kyu Lee ),( Sang-ha Kim ),( Won-yeon Lee ),( Suk Joong Yong ),( Beomsu Shin ) 대한결핵 및 호흡기학회 2019 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.127 No.-

Purpose: Endobronchial tuberculosis (EBTB) is a chronic inflammatory disease characterized by destruction of tracheobronchial tree due to Mycobacterium tuberculosis (MTB). MTB can inhibit mucociliary clearance, destroy respiratory epithelium and produce biofilms. It affects the airways’ microenvironment. However, little is known about the respiratory microorganisms in patients with EBTB. Method: We retrospectively reviewed data for pathologically confirmed EBTB patients diagnosed at a tertiary referral hospital in South Korea between Jan 2013 and Jan 2019. Bronchoscopy and bacterial culture of the bronchial washing fluids were done in every patient. Result: A total of 216 patients with EBTB were included. The median age of the patients was 73 years, 142 (65.7%) were female, and 32 (14.8%) had a history of previous tuberculosis treatment. By bronchoscopic classification of EBTB, actively caseating, edematous-hyperemic, and fibrostenotic types were observed in 114 (52.8%), 32 (14.8%), and 33 (15.3%), respectively. Bacterial culture of the bronchial washing fluids showed microorganisms in 42 (19.4%) patients. Among them, 6 (2.8%) had multiple microbial species. The most common microorganisms identified were Staphylococcus aureus isolated in 14 patients (33.3%), followed by Klebsiella species in 12 (28.6%, 10 Klebsiella pneumoniae, 2 Klebsiella oxytoca), Streptococcus species in 5 (11.9%), Enterobacter species in 4 (9.5%), and Pseudomonas aeruginosa in 3 (7.1%). Conclusion: Variety of microorganisms were isolated in the bronchial washing fluids, these changes in the composition of microorganisms take place in the airways of patients with EBTB. Further studies are needed to investigate its clinical significance.

그림설문지를 이용한 유아 대상 영양교육 효과 분석

홍샛별(Saet Byol Hong),박혜련(Hae Ryun Park),고경아(Gyeong Ah Go),정계옥(Gye Ok Jeong),송경희(Kyung Hee Song) 대한지역사회영양학회 2010 대한지역사회영양학회지 Vol.15 No.4

The purpose of this study was to evaluate the effect of the nutrition education on preschool children`s nutrition knowledge and behaviors. The study subjects were preschool children attending J kindergarten located in Wonju. Each of the control group and the education group consisted of 49 children and the education group was exposed to nutrition education while the control group did not. The nutrition education intervention lasted 9 weeks weekly basis. The t-test for the homogeneity of each group showed no meaningful difference at the beginning point of nutrition education. After nutrition education a test of nutrition knowledge using picture-questionnaire was carried out by the researcher for the subjects of education group and control group and the caretakers of the education group were offered self-administered questionnaire on the changes in children`s dietary behaviors. The results of the study were as follows: 1. Nutrition education intervention showed a meaningful difference in children`s understanding nutrition; the kinds and function of food, the relationship between food and body, the function of nutrients and enhanced their idea on hygiene compared to the control group (p < p.005). 2. However, nutrition education intervention made no statistically meaningful difference in children`s dietary behaviors such as having breakfast, keeping balanced diet, washing hands before meals, saying “thanks” before and after meals, cleaning the table after meals, brushing teeth after meals and so on. Therefore, we found that it is hard to expect children to correct their dietary behaviors in such a short period of 9 weeks and nutrition education for preschool children should be offered to caretakers at the same time. (Korean J Community Nutrition 15(4): 475~484, 2010)

Collateral projection from the locus coeruleus to whisker-related sensory and motor brain regions of the rat

Lee, Sat-Byol,Beak, Suk K.,Park, Seung H.,Waterhouse, Barry D.,Lee, Hyun S. Wiley Subscription Services, Inc., A Wiley Company 2009 Journal of comparative neurology Vol.514 No.4

<P>The primary goal of this study was to examine whether the locus coeruleus (LC) provides collateral projections to whisker-related, sensorimotor brain regions. After injections of retrograde tracers into the primary sensory (S1) barrel field/primary whisker motor (M1) cortices, ventroposteromedial (VPM)/ventrolateral (VL) thalamic nuclei, or principal sensory trigeminal (Pr5)/facial motor (Mo7) nuclei, the distribution of double-labeled neurons within the LC was examined. Our observations indicated that a large number of individual LC cells provided axon collaterals to S1-M1 or VPM-VL regions, whereas only a few projected to Pr5-Mo7 nuclei. The laterality and the distribution of dual-projecting LC neurons were as follows. 1) The neurons projecting to the S1-M1 cortices were predominantly ipsilateral (96% ± 0.7%). Labeled neurons were located ventrally at the rostral pole but were evenly distributed along the dorsoventral aspect of the principal LC. 2) The cells projecting to the VPM-VL nuclei were bilateral, with ipsilateral (68% ± 2.3%) dominance. Neurons were observed at the rostrocaudal extent of the LC, where the labeling was most pronounced at the ventral, principal LC. 3) The neurons projecting to the Pr5-Mo7 regions exhibited slightly contralateral (56% ± 2.9%) dominance, where labeled cells were confined within the ventral margin of the principal subdivision. Taken together, the present observations demonstrate that each subdivision of the LC possesses a differential functional organization with respect to its collateral projection to whisker-related sensorimotor targets, suggesting that the nucleus might play a modulatory role in vibrissal sensorimotor integration that allows the guidance of behavioral action essential for the survival of the animal. J. Comp. Neurol. 514:387–402, 2009. © 2009 Wiley-Liss, Inc.</P>

한국사회의 고급문화와 대중문화의 상징적 경계에 대한 예비적 고찰

최샛별(Set Byol Choi) 이화여자대학교 이화사회과학원 2006 사회과학연구논총 Vol.16 No.-

상징적 경계라는 개념은 1960년대부터 상징적 체계와 간접적 형태의 권력에 대한 연구들이 수렴되면서 그 중요성이 부각되었으며, 현재 사회과학전반에 걸쳐 새롭게 부상하는 중요한 학문적 조류에서 핵심역할을 담당하고 있다. 그러나 아직 한국학계에서는 관련 연구가 많이 진행되고 있지 않으며, 특히 그 중에서도 상징적 경계가 인지적 도구로서 사람들의 사고 속에 자리 잡고 있다는 것을 강조하는 인지적 측면에서의 연구는 거의 이루어지고 있지 않다. 이 논문은 2005년 대학생 1.419명으로 대상으로 실시된 음악장르에 대한 고급스러움의 인지정도를 통하여, 상징적 경계의 인지적 차원에서의 대표적인 연구주제라고 할 수 있는 대중문화와 고급문화의 경계의 한국적 지형에 대한 기초적인 접근을 시도한다. 그 결과 2005년 한국사회 음악의 인지적인 경계는 전통적인 고급문화라고 할 수 있는 클래식을 최상위로 그리고 성인가요를 최하위로 하는 위계적 구조를 보여주고 있다. 상식적으로 가지고 있는 고급문화와 대중문화의 위계와 구별되는 특징으로는 고급문화라고 할 수 있는 클래식과 대중문화라고 할 수 있는 음악 장르와의 차이보다는 대중음악장르 내에서의 위계의 차이가 더 크게 나타났으며, 서구 또는 외국음악이 같은 장르의 국내음악보다 높은 위계를 갖는 것으로 나타났다. 이는 현대사회에서의 대중문화의 위치의 변화와 한국사회의 역사적 특수성을 반영하는 것으로 분석된다. The concept "symbolic boundaries" has gained importance since the 1960s when studies on symbolic system and indirect form of power began to converge. Now it is a core concept in a newly emerging field of social sciences. Yet, there are few studies done on symbolic boundaries in Korea, let alone on the cognitive aspect which emphasizes that symbolic boundaries are rooted in people as a cognitive tool. Analyzing 1419 college students surveyed in 2005, this study attempts to draw a Korean map of boundaries between high culture and popular culture by looking into who considers which musical genre high quality. The result shows that cognitive boundaries of Korean society in 2005 puts classical music at the top of the hierarchy with Korean adult pop at the bottom. And the hierarchical difference within popular music genres is greater than the difference between classical music and popular music. Within the same genre of music, western music or foreign music occupies higher hierarchy than domestic music. It seems to reflect changes in the position of popular culture and historical peculiarity of Korean society.

다중시기 항공사진과 현장조사를 통한 해안침식 변화 연구: 태안반도를 사례로

우한별 ( Han Byol Woo ),장동호 ( Dong Ho Jang ) 한국지형학회 2010 한국지형학회지 Vol.17 No.4

이 연구에서는 다중시기 항공사진과 현장조사를 통하여 충남 태안반도 지역의 해식애를 대상으로 해안선 후퇴량을 산정하고 계절적 지형 특성과 침식 현황을 파악하였다. 연구결과, 정사보정된 항공사진을 이용한 분석에서 파도리와 둔두리 지역은 해식애의 침식이 진행 될수록 해안선의 길이와 침식 면적이 증가하는 것으로 나타났다. 해식애의 계절별 변화 특성과 후퇴 변화량을 정량적으로 파악하기 위해 침식기준목을 설치하여 침식기준목의 상, 중, 하 위치에 해당하는 곳에서 가장 가까운 기반암과의 거리를 직각으로 반복 측정한 결과, 연구지역에서는 봄철에서 여름철까지 점차 후퇴량이 증가하다가, 가을철에 다소 감소하는 것으로 나타났다. 특히 7월에서 9월간 한반도에 직접적인 영향을 끼친 여름철 태풍의 영향으로 해식애의 후퇴가 다른 기간에 비해 급격하게 진행된 것으로 판단된다. 겨울철에는 해식애 노두가 결빙작용과 해빙작용을 반복하면서 기계적 풍화가 활발히 진행되어 후퇴량이 소폭 증가하였다. 해식애 지역의 계절별 지형 변화 양상과 침식 현황을 파악하기 위하여 매달 사진촬영과 그 양상을 분석한 결과, 연구지역에서의 해안선 후퇴는 해식애 기저부의 침식, 사태, 사면 퇴적 암설의 형성 그리고 이 암설의 침식(소멸)의 순차적인 순환에 의해 반복적으로 이루어지는 것으로 나타났다. In this study, the volume of shoreline retreat at sea-cliffs in the Taean peninsula (West Coast of Korea) was estimated and their erosion and seasonal landforms characteristics changes were investigated through multi-temporal aerial photographs and field survey. Based on the analysis of aerial photographs through ortho-correction, the results show that the length of shoreline and erosion area increase as erosion at sea-cliffs occurs in Pado-li and Dundu-li. To obtain the seasonal quantitative landforms changes and retreat of sea-cliffs, we marked top, middle, and bottom datum-points, from which the distance to the nearest bedrock was repeatedly measured. In these regions, the retreat of sea-cliffs gradually increases in spring to summer, but gradually decreases in autumn. In particular, the typhoon that has a great influence on the Korean peninsula in July to September in summer would drastically increase the retreat of sea-cliffs in comparison with other seasons. As the outcrop of sea-cliffs repeats freezing and thawing in winter, the retreat of sea-cliffs increases a little due to active mechanical weathering. To know the erosion and seasonal landforms changes of sea-cliffs, we took pictures of them in every month and then analyze their condition. The retreat of sea-cliffs was repeatedly occurred by the circulation of the erosion of sea-cliff base, landslides, the formation of slope sediment debris and their erosion, in that order.

연구논문 : 한국의 문화자본 지형도 구성을 위한 척도개발 기초연구; 문화예술 활동과 음악선호를 중심으로

최샛별 ( Set Byol Choi ),이명진 ( Myoung Jin Lee ) 한국조사연구학회 2012 조사연구 Vol.13 No.1

본 연구는 대규모 조사 자료에 근거한 한국 사회의 문화자본 지형도를 구성하기 위한 기초 연구의 일환으로, 다른 국가들에서 집적된 기존 자료와의 비교가 가능하면서도 동시에 현재 한국 사회에 적합한 질문 문항을 제시하는 것을 목적으로 한다. 이를 위해 본 연구에서는 광범위한 국내의 문화자본 관련 문헌들에 대한 비판적 고찰을 통해 이론적 배경을 확립하고, 주요 문헌과 조사에서 사용한 척도 및 관련 질문지와 자료를 수집하였다. 이를 토대로 질문지에서 다루어야 할 주요 영역과 차원을 선정하고 선정된 각 영역과 차원을 고려하여 한국 사회에 보다 적합한 질문 문항을 개발하기 위해 각 분야별 문헌조사와 전문가 조사, 그리고 대상자 질적 조사를 수행하였다. 이상의 절차를 통해 본 연구는, 문화예술 활동과 음악장르를 주요 영역으로 선정하고 문화의 ``고급/대중`` 차원과 ``소비/생산`` 차원, 그리고 한국적 특수성을 고려하여 구체적인 항목을 구성하였다. 그리고 이렇게 구성된 각 항목들에 대해서는 그 동안 문화자본의 보유 정도를 측정함에 있어 기존의 연구들에서 일관성 없이 사용된 문화자본 측정의 세 가지 측면(선호, 참여, 인지)을 통합·보완하여, 각 항목을 좋아하는 정도(선호), 각 항목에 참여하는 정도(참여), 그리고 각 항목이 고급스럽다고 생각하는 정도(인지)와 각 항목이 멋있다고 생각하는 정도(인지)를 묻는 질문 문항을 개발하였다. 본 연구는 문화자본에 관한 기존의 연구들에서 사용된 방대한 양의 질문 문항들을 비판적으로 고찰하고, 이에 한국적 특수성을 고려한 항목들을 추가하여 보다 한국적인 문화자본을 찾아낼 수 있는 큰 틀을 마련하고, 이로써 그 동안 서구 중심적으로 진행되어 왔던 문화자본 논의에 있어서의 비서구적 공백을 메울 수 있는 기반을 제공한다는 점에서 의의를 갖는다. This research is a part of a fundamental research to form the topographic map of the South Korean society`s cultural capital, based on large scale research data. Its purpose is to suggest suitable questions for today`s Korean society as well as to compare with previous data accumulated from other nations. For this, this research is to establish theoretical background through critical study on the extensive literature on domestic and foreign cultural capital and collect measures, questionnaires, and data used in important literature and surveys. Based on this, the major domains and levels that should be dealt in the questionnaire were chosen, literature review was conducted for each field; experts were investigated in order to develop questions more suitable for the Korean society considering each domain and level, and qualitative research on the subjects were conducted. This research as seen through the above processes, music genres and culture activities were chosen as major domains, "high/popular" level and "consumption/ production" level were chosen as items, and specific items were composed considering Korea`s distinct characteristics. Each of these items combine and complement the three aspects of measuring cultural capital(preference, participation, perception), which have been used incoherently in previous researches in measuring the level of possession in cultural capital. This led to developing questions such as the level of liking each item(preference), the level of participating in each item(participation), the level of luxuriousness in each item(perception), and the level of stylishness in each item(perception). This research holds significance in that it critically examines the vast amount of questionnaires used in the past for cultural capital research, provides a large framework to find Korean cultural capital by adding items considering Korea`s distinct characteristics, and provides groundwork to fill in the non-Western gap in the discussion of cultural capital, which has been based on the West.