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Ghosh, Saptarshi,Rao, Pamidimukkala Bramhananda,Kotne, Sivasankar Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.16
Background: Although 3D image based brachytherapy is currently the standard of treatment in cervical cancer, most of the centres in developing countries still practice orthogonal intracavitary brachytherapy due to financial constraints. The quest for optimum dose and fractionation schedule in high dose rate (HDR) intracavitary brachytherapy (ICBT) is still ongoing. While the American Brachytherapy Society recommends four to eight fractions of each less than 7.5 Gy, there are some studies demonstrating similar efficacy and comparable toxicity with higher doses per fraction. Objective: To assess the treatment efficacy and late complications of HDR ICBT with 9 Gy per fraction in two fractions. Materials and Methods: This is a prospective institutional study in Southern India carried on from $1^{st}$ June 2012 to $31^{st}$ July 2014. In this period, 76 patients of cervical cancer satisfying our inclusion criteria were treated with concurrent chemo-radiation following ICBT with 9 Gy per fraction in two fractions, five to seven days apart. Results: The median follow-up period in the study was 24 months (range 10.6 - 31.2 months). The 2 year actuarial local control rate, disease-free survival and overall survival were 88.1%, 84.2% and 81.8% respectively. Although 38.2% patients suffered from late toxicity, only 3 patients had grade III late toxicity. Conclusions: In our experience, HDR brachytherapy with 9 Gy per fraction in two fractions is an effective dose fractionation for the treatment of cervical cancer with acceptable toxicity.
Sadhu, Nithya Lavanya,Teegala, Bramhananda Reddy,Marapu, Vijay Kumar The Korean Institute of Power Electronics 2020 JOURNAL OF POWER ELECTRONICS Vol.20 No.6
High amounts of harmonics cause noise and electromagnetic interference to nearby systems. Pulsewidth modulation (PWM) techniques are used to reduce the amount of harmonics near the multiples of switching frequencies. To trim down the noise and electromagnetic interference and improve the quality of the output voltages, different types of constant and variable switching frequency random PWM techniques for dual inverter-fed open-end winding induction motor drive configuration are discussed in this study. Moreover, the vector control technique is used along with random PWM techniques to improve the transient response of the dual inverter.
M. Harsha Vardhan Reddy,T. Bramhananda Reddy,B. Ravindranath Reddy,M. Suryakalavathi 전력전자학회 2015 JOURNAL OF POWER ELECTRONICS Vol.15 No.6
Conventional space vector pulse width modulation based asymmetrical dual inverter configuration produces high common mode voltage (CMV) variations. This CMV causes the flow of common mode current, which adversely affects the motor bearings and electromagnetic interference of nearby electronic systems. In this study, a simple and generalized carrier based pulse width modulation (PWM) technique is proposed for dual inverter configuration. This simple approach generates various continuous and discontinuous modulating signals based PWM algorithms. With the application of the discontinuous modulating signal based PWM algorithm to the asymmetrical dual inverter configuration, the CMV can be reduced with a slightly improved quality of output voltage. The performance of the continuous and discontinuous modulating signals based PWM algorithms is explored through both theoretical and experimental studies. Results show that the discontinuous modulating signal based PWM algorithm efficiently reduces the CMV and switching losses.
Reddy, M. Harsha Vardhan,Reddy, T. Bramhananda,Reddy, B. Ravindranath,Suryakalavathi, M. The Korean Institute of Power Electronics 2015 JOURNAL OF POWER ELECTRONICS Vol.15 No.6
Conventional space vector pulse width modulation based asymmetrical dual inverter configuration produces high common mode voltage (CMV) variations. This CMV causes the flow of common mode current, which adversely affects the motor bearings and electromagnetic interference of nearby electronic systems. In this study, a simple and generalized carrier based pulse width modulation (PWM) technique is proposed for dual inverter configuration. This simple approach generates various continuous and discontinuous modulating signals based PWM algorithms. With the application of the discontinuous modulating signal based PWM algorithm to the asymmetrical dual inverter configuration, the CMV can be reduced with a slightly improved quality of output voltage. The performance of the continuous and discontinuous modulating signals based PWM algorithms is explored through both theoretical and experimental studies. Results show that the discontinuous modulating signal based PWM algorithm efficiently reduces the CMV and switching losses.